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Protein Ontology report - microsomal triglyceride transfer protein large subunit
PR:000003392 - http://purl.obolibrary.org/obo/PR_000003392
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003392   
  PRO namemicrosomal triglyceride transfer protein large subunit 
  Synonyms
PRO-Short-label: EXACT:MTTP
Gene-based: RELATED:MTP
  Definition"A protein that is a translation product of the human MTTP gene or a 1:1 ortholog thereof." [MGI:106926, PRO:HJD] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification2                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF016634
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003392

microsomal triglyceride transfer protein large subunit

MTTP


"A protein that is a translation product of the human MTTP gene or a 1:1 ortholog thereof." [MGI:106926, PRO:HJD]


organism-gene



PR:A0A0R4IVV0

microsomal triglyceride transfer protein large subunit (zebrafish)

z-MTTP


"A microsomal triglyceride transfer protein large subunit that is encoded in the genome of zebrafish." [OMA:A0A0R4IVV0, PRO:DNx]


organism-gene



PR:D4A1W8

microsomal triglyceride transfer protein large subunit (rat)

rMTTP


"A microsomal triglyceride transfer protein large subunit that is encoded in the genome of rat." [OMA:D4A1W8, PRO:DNx]


organism-gene



PR:O08601

microsomal triglyceride transfer protein large subunit (mouse)

mMTTP


"A microsomal triglyceride transfer protein large subunit that is encoded in the genome of mouse." [OMA:O08601, PRO:DNx]


organism-sequence



PR:O08601-1

microsomal triglyceride transfer protein large subunit isoform 1 (mouse)

mMTTP/iso:1


"A microsomal triglyceride transfer protein large subunit isoform 1 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:O08601-2

microsomal triglyceride transfer protein large subunit isoform 2 (mouse)

mMTTP/iso:2


"A microsomal triglyceride transfer protein large subunit isoform 2 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-gene



PR:P55157

microsomal triglyceride transfer protein large subunit (human)

hMTTP


"A microsomal triglyceride transfer protein large subunit that is encoded in the genome of human." [PRO:HJD, UniProtKB:P55157]


organism-sequence



PR:P55157-1

microsomal triglyceride transfer protein large subunit isoform h1 (human)

hMTTP/iso:h1


"A microsomal triglyceride transfer protein large subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55157-1." [PRO:DNx, UniProtKB:P55157]


organism-sequence



PR:P55157-2

microsomal triglyceride transfer protein large subunit isoform h2 (human)

hMTTP/iso:h2


"A microsomal triglyceride transfer protein large subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55157-2." [PRO:DNx, UniProtKB:P55157]


organism-modification



PR:000048476

microsomal triglyceride transfer protein large subunit, signal peptide removed form (human)

hMTTP/SigPep-


"A microsomal triglyceride transfer protein large subunit (human) that has had the signal peptide removed. UniProtKB:P55157, 19-894." [PRO:DNx, Reactome:R-HSA-174688]


organism-modification



PR:000074284

microsomal triglyceride transfer protein large subunit deaminated 1 (human)

hMTTP/Deam:1


"A microsomal triglyceride transfer protein large subunit (human) that has been deaminated on the residue at the position equivalent to Asn-559 of the amino acid sequence represented by UniProtKB:P55157-1. Example: UniProtKB:P55157-1, Asn-559, MOD:00684." [IEDB_epitope:1984796, PRO:DNx]


organism-modification



PR:000084813

microsomal triglyceride transfer protein large subunit cysteinylated 1 (human)

hMTTP/Cyst:1


"A microsomal triglyceride transfer protein large subunit (human) that has been cysteinylated on the residue at the position equivalent to Cys-827 of the amino acid sequence represented by UniProtKB:P55157-1. Example: UniProtKB:P55157-1, Cys-827, MOD:00765." [IEDB_epitope:1588374, IEDB_epitope:1594146, PRO:DNx]


organism-gene



PR:Q9VIH3

microsomal triacylglycerol transfer protein (fruit fly)

fly-MTTP


"A microsomal triglyceride transfer protein large subunit that is encoded in the genome of fruit fly." [OMA:Q9VIH3, PRO:DNx]


sequence



PR:000003448

microsomal triglyceride transfer protein large subunit isoform 1

MTTP/iso:1


"A microsomal triglyceride transfer protein large subunit that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O08601-1 or a 1:1 ortholog thereof." [PMID:17312007, PRO:HJD]


organism-sequence



PR:O08601-1

microsomal triglyceride transfer protein large subunit isoform 1 (mouse)

mMTTP/iso:1


"A microsomal triglyceride transfer protein large subunit isoform 1 that is encoded in the genome of mouse." [PRO:HJD]

Yes

modification



PR:000026584

microsomal triglyceride transfer protein large subunit isoform 1, signal peptide removed form

MTTP/iso:1/SigPep-


"A microsomal triglyceride transfer protein large subunit isoform 1 that has had the signal peptide removed." [PRO:DNx]


sequence



PR:000003449

microsomal triglyceride transfer protein large subunit isoform 2

MTTP/iso:2


"A microsomal triglyceride transfer protein large subunit that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O08601-2 or a 1:1 ortholog thereof." [PMID:17312007, PRO:HJD]


organism-sequence



PR:O08601-2

microsomal triglyceride transfer protein large subunit isoform 2 (mouse)

mMTTP/iso:2


"A microsomal triglyceride transfer protein large subunit isoform 2 that is encoded in the genome of mouse." [PRO:HJD]

Yes

modification



PR:000026583

microsomal triglyceride transfer protein large subunit, signal peptide removed form

MTTP/SigPep-


"A microsomal triglyceride transfer protein large subunit that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026584

microsomal triglyceride transfer protein large subunit isoform 1, signal peptide removed form

MTTP/iso:1/SigPep-


"A microsomal triglyceride transfer protein large subunit isoform 1 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000048476

microsomal triglyceride transfer protein large subunit, signal peptide removed form (human)

hMTTP/SigPep-


"A microsomal triglyceride transfer protein large subunit (human) that has had the signal peptide removed. UniProtKB:P55157, 19-894." [PRO:DNx, Reactome:R-HSA-174688]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O08601-1 mMTTP/iso:1 acts_upstream_of_or_withinGO:0006497 protein lipidation PMID:12072432
GO:0006629 lipid metabolic process PMID:12072432
GO:0006641 triglyceride metabolic process PMID:12072432
GO:0042953 lipoprotein transport MGI_ref:3722967; PMID:17635917
enablesGO:0005515 protein binding with PR:Q8R4U2 Cgri-P4HB MGI_ref:3722967; PMID:17635917
located_inGO:0005783 endoplasmic reticulum MGI_ref:3722967; PMID:17635917
PR:O08601-2 mMTTP/iso:2 acts_upstream_of_or_withinGO:0042953 lipoprotein transport PMID:17312007
GO:0042953 lipoprotein transport PMID:17312007
enablesGO:0005515 protein binding with PR:Q8R4U2 Cgri-P4HB MGI_ref:3722967; PMID:17635917
located_inGO:0005794 Golgi apparatus PMID:17312007