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Protein Ontology report - RNA-binding protein FXR1
PR:000003390 - http://purl.obolibrary.org/obo/PR_000003390
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003390   
  PRO nameRNA-binding protein FXR1 
  Synonyms
PRO-Short-label: EXACT:FXR1
Gene-based: RELATED:Fxr1h
Other: EXACT:fragile X mental retardation syndrome-related protein 1 | FXR1p
  Definition"A fragile X-related protein that is a translation product of the human FXR1 gene or a 1:1 ortholog thereof." [MGI:104860, PRO:HJD] 
  PRO Categorygene 
  ParentPR:000003222 fragile X-related protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence7                                                  Organism-Sequence 13                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003390

RNA-binding protein FXR1

FXR1


"A fragile X-related protein that is a translation product of the human FXR1 gene or a 1:1 ortholog thereof." [MGI:104860, PRO:HJD]


organism-gene



PR:F1QLR3

RNA-binding protein FXR1 (zebrafish)

z-FXR1


"An RNA-binding protein FXR1 that is encoded in the genome of zebrafish." [PRO:HJD]


organism-sequence



PR:F1QLR3-1

RNA-binding protein FXR1 isoform 1 (zebrafish)

z-FXR1/iso:1


"An RNA-binding protein FXR1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F1QLR3-1." [PRO:DNx, UniProtKB:F1QLR3]


organism-sequence



PR:F1QLR3-2

RNA-binding protein FXR1 isoform 2 (zebrafish)

z-FXR1/iso:2


"An RNA-binding protein FXR1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F1QLR3-2." [PRO:DNx, UniProtKB:F1QLR3]


organism-sequence



PR:F1QLR3-3

RNA-binding protein FXR1 isoform 3 (zebrafish)

z-FXR1/iso:3


"An RNA-binding protein FXR1 (zebrafish) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F1QLR3-3." [PRO:DNx, UniProtKB:F1QLR3]


organism-gene



PR:P51114

RNA-binding protein FXR1 (human)

hFXR1


"An RNA-binding protein FXR1 that is encoded in the genome of human." [PRO:HJD, UniProtKB:P51114]


organism-sequence



PR:P51114-1

RNA-binding protein FXR1 isoform D (human)

hFXR1/iso:D


"An RNA-binding protein FXR1 isoform D that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:P51114-2

RNA-binding protein FXR1 isoform A (human)

hFXR1/iso:A


"An RNA-binding protein FXR1 isoform A that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:P51114-3

RNA-binding protein FXR1 isoform 3 (human)

hFXR1/iso:3


"An RNA-binding protein FXR1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51114-3." [PRO:DNx, UniProtKB:P51114]


organism-modification



PR:000045816

RNA-binding protein FXR1 phosphorylated 1 (human)

hFXR1/Phos:1


"An RNA-binding protein FXR1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-420 of the amino acid sequence represented by UniProtKB:P51114-1. Example: UniProtKB:P51114-1, Ser-420, MOD:00046." [iPTMnet:P51114, PMID:20417602]


organism-modification



PR:000073243

RNA-binding protein FXR1 methylated 1 (human)

hFXR1/Me:1


"An RNA-binding protein FXR1 (human) that has been methylated on the residue at the position equivalent to Arg-459 of the amino acid sequence represented by UniProtKB:P51114-1. Example: UniProtKB:P51114-1, Arg-459, MOD:00658." [IEDB_epitope:569116, IEDB_epitope:569117, PRO:DNx]


organism-modification



PR:000074223

RNA-binding protein FXR1 methylated 2 (human)

hFXR1/Me:2


"An RNA-binding protein FXR1 (human) that has been methylated on the residue at the position equivalent to Cys-211 of the amino acid sequence represented by UniProtKB:P51114-1. Example: UniProtKB:P51114-1, Cys-211, MOD:00660." [IEDB_epitope:1028660, PRO:DNx]


organism-modification



PR:000083483

RNA-binding protein FXR1 methylated 3 (human)

hFXR1/Me:3


"An RNA-binding protein FXR1 (human) that has been methylated on the residue at the position equivalent to Cys-157 of the amino acid sequence represented by UniProtKB:P51114-1. Example: UniProtKB:P51114-1, Cys-157, MOD:00660." [IEDB_epitope:1004976, PRO:DNx]


organism-gene



PR:Q5F3S6

uncharacterized protein, RCJMB04_7n20 translation product (chicken)

chick-FXR1


"An RNA-binding protein FXR1 that is encoded in the genome of chicken." [OMA:Q5F3S6, PRO:DNx]


organism-gene



PR:Q5XI81

RNA-binding protein FXR1 (rat)

rFXR1


"An RNA-binding protein FXR1 that is encoded in the genome of rat." [OMA:Q5XI81, PRO:DNx]


organism-gene



PR:Q61584

RNA-binding protein FXR1 (mouse)

mFXR1


"An RNA-binding protein FXR1 that is encoded in the genome of mouse." [OMA:Q61584, PRO:DNx]


organism-sequence



PR:Q61584-1

RNA-binding protein FXR1 isoform E (mouse)

mFXR1/iso:E


"An RNA-binding protein FXR1 isoform E that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:Q61584-2

RNA-binding protein FXR1 isoform A (mouse)

mFXR1/iso:A


"An RNA-binding protein FXR1 isoform A that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:Q61584-3

RNA-binding protein FXR1 isoform B (mouse)

mFXR1/iso:B


"An RNA-binding protein FXR1 isoform B that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:Q61584-4

RNA-binding protein FXR1 isoform C (mouse)

mFXR1/iso:C


"An RNA-binding protein FXR1 isoform C that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:Q61584-5

RNA-binding protein FXR1 isoform D (mouse)

mFXR1/iso:D


"An RNA-binding protein FXR1 isoform D that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:Q61584-6

RNA-binding protein FXR1 isoform F (mouse)

mFXR1/iso:F


"An RNA-binding protein FXR1 isoform F that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:Q61584-7

RNA-binding protein FXR1 isoform G (mouse)

mFXR1/iso:G


"An RNA-binding protein FXR1 isoform G that is encoded in the genome of mouse." [PRO:HJD]

Yes

sequence



PR:000003393

RNA-binding protein FXR1 isoform E

FXR1/iso:E


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-1 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:Q61584-1

RNA-binding protein FXR1 isoform E (mouse)

mFXR1/iso:E


"An RNA-binding protein FXR1 isoform E that is encoded in the genome of mouse." [PRO:HJD]

Yes

sequence



PR:000003395

RNA-binding protein FXR1 isoform A

FXR1/iso:A


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-2 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:P51114-2

RNA-binding protein FXR1 isoform A (human)

hFXR1/iso:A


"An RNA-binding protein FXR1 isoform A that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q61584-2

RNA-binding protein FXR1 isoform A (mouse)

mFXR1/iso:A


"An RNA-binding protein FXR1 isoform A that is encoded in the genome of mouse." [PRO:HJD]

Yes

sequence



PR:000003397

RNA-binding protein FXR1 isoform B

FXR1/iso:B


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-3 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:Q61584-3

RNA-binding protein FXR1 isoform B (mouse)

mFXR1/iso:B


"An RNA-binding protein FXR1 isoform B that is encoded in the genome of mouse." [PRO:HJD]


sequence



PR:000003399

RNA-binding protein FXR1 isoform C

FXR1/iso:C


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-4 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:Q61584-4

RNA-binding protein FXR1 isoform C (mouse)

mFXR1/iso:C


"An RNA-binding protein FXR1 isoform C that is encoded in the genome of mouse." [PRO:HJD]


sequence



PR:000003401

RNA-binding protein FXR1 isoform D

FXR1/iso:D


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-5 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:P51114-1

RNA-binding protein FXR1 isoform D (human)

hFXR1/iso:D


"An RNA-binding protein FXR1 isoform D that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:Q61584-5

RNA-binding protein FXR1 isoform D (mouse)

mFXR1/iso:D


"An RNA-binding protein FXR1 isoform D that is encoded in the genome of mouse." [PRO:HJD]

Yes

sequence



PR:000003403

RNA-binding protein FXR1 isoform F

FXR1/iso:F


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-6 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:Q61584-6

RNA-binding protein FXR1 isoform F (mouse)

mFXR1/iso:F


"An RNA-binding protein FXR1 isoform F that is encoded in the genome of mouse." [PRO:HJD]

Yes

sequence



PR:000003405

RNA-binding protein FXR1 isoform G

FXR1/iso:G


"An RNA-binding protein FXR1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61584-7 or a 1:1 ortholog thereof." [PMID:10409431, PRO:HJD]


organism-sequence



PR:Q61584-7

RNA-binding protein FXR1 isoform G (mouse)

mFXR1/iso:G


"An RNA-binding protein FXR1 isoform G that is encoded in the genome of mouse." [PRO:HJD]

Yes

modification



PR:000018816

RNA-binding protein FXR1, initiator methionine removed form

FXR1/InitMet-


"An RNA-binding protein FXR1 that has had the initiator methionine removed." [PRO:DNx]


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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0017148 negative regulation of translationPR:Q61584-5 mFXR1/iso:D MGI_ref:3573966; PMID:15548538

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0002151 G-quadruplex RNA bindingPR:Q61584-1 mFXR1/iso:E MGI_ref:3699977; PMID:17170008
NOT GO:0002151 G-quadruplex RNA bindingPR:Q61584-2 mFXR1/iso:A MGI_ref:3699977; PMID:17170008
PR:Q61584-5 mFXR1/iso:D MGI_ref:3699977; PMID:17170008
GO:0003730 mRNA 3'-UTR bindingPR:Q61584-5 mFXR1/iso:D MGI_ref:3573966; PMID:15548538

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:Q61584-1 mFXR1/iso:E PMID:11178106
PR:Q61584-6 mFXR1/iso:F PMID:11178106
PR:Q61584-7 mFXR1/iso:G PMID:11178106
GO:0005737 cytoplasmPR:Q61584-1 mFXR1/iso:E MGI_ref:3760313; PMID:11178106
PR:Q61584-5 mFXR1/iso:D MGI_ref:3573966; PMID:15548538
PR:Q61584-6 mFXR1/iso:F PMID:11178106
PR:Q61584-7 mFXR1/iso:G MGI_ref:3760313; PMID:11178106
GO:0005840 ribosomePR:Q61584-1 mFXR1/iso:E MGI_ref:3760313; PMID:11178106
PR:Q61584-6 mFXR1/iso:F PMID:11178106
PR:Q61584-7 mFXR1/iso:G MGI_ref:3760313; PMID:11178106
GO:0043034 costamerePR:Q61584-1 mFXR1/iso:E PMID:15128702