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Protein Ontology report - syntaxin-binding protein
PR:000003316 - http://purl.obolibrary.org/obo/PR_000003316
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003316   
  PRO namesyntaxin-binding protein 
  Definition"A protein that is a translation product of the human STXBP1, STXBP2, or STXBP3 genes, or 1:1 orthologs thereof. This class is related to the fungal sec-1 protein." [PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000003316

syntaxin-binding protein

INPP5D/iso:6


"A protein that is a translation product of the human STXBP1, STXBP2, or STXBP3 genes, or 1:1 orthologs thereof. This class is related to the fungal sec-1 protein." [PRO:CNA]


gene



PR:000003317

syntaxin-binding protein 1

STXBP1


"A syntaxin-binding protein that is a translation product of the human STXBP1 gene or a 1:1 ortholog thereof." [MGI:107363, PRO:HJD]


organism-gene



PR:O08599

syntaxin-binding protein 1 (mouse)

mSTXBP1


"A syntaxin-binding protein 1 that is encoded in the genome of mouse." [OMA:O08599, PRO:DNx]

Yes

organism-sequence



PR:O08599-1

syntaxin-binding protein 1 isoform 1 (mouse)

mSTXBP1/iso:1


"A syntaxin-binding protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:O08599-2

syntaxin-binding protein 1 isoform 2 (mouse)

mSTXBP1/iso:2


"A syntaxin-binding protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]


organism-gene



PR:P34815

acetylcholine regulator unc-18 (worm)

STXBP1 (worm)


"A syntaxin-binding protein 1 that is encoded in the genome of worm." [OMA:P34815, PRO:DNx]


organism-gene



PR:P61764

syntaxin-binding protein 1 (human)

hSTXBP1


"A syntaxin-binding protein 1 that is encoded in the genome of human." [PRO:HJD, UniProtKB:P61764]


organism-sequence



PR:P61764-1

syntaxin-binding protein 1 isoform 1 (human)

hSTXBP1/iso:1


"A syntaxin-binding protein 1 isoform 1 that is encoded in the genome of human." [PRO:HJD]


organism-sequence



PR:P61764-2

syntaxin-binding protein 1 isoform 2 (human)

hSTXBP1/iso:2


"A syntaxin-binding protein 1 isoform 2 that is encoded in the genome of human." [PRO:HJD]


organism-modification



PR:000066280

syntaxin-binding protein 1 cysteinylated 1 (human)

hSTXBP1/Cyst:1


"A syntaxin-binding protein 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-354 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-354, MOD:00765." [IEDB_epitope:1573008, PRO:DNx]


organism-modification



PR:000068899

syntaxin-binding protein 1 cysteinylated 2 (human)

hSTXBP1/Cyst:2


"A syntaxin-binding protein 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-552 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-552, MOD:00765." [IEDB_epitope:1587393, PRO:DNx]


organism-modification



PR:000076026

syntaxin-binding protein 1 methylated 1 (human)

hSTXBP1/Me:1


"A syntaxin-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-366 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-366, MOD:00660." [IEDB_epitope:1016916, PRO:DNx]


organism-modification



PR:000077554

syntaxin-binding protein 1 methylated 2 (human)

hSTXBP1/Me:2


"A syntaxin-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-110 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-110, MOD:00660." [IEDB_epitope:1004125, PRO:DNx]


organism-modification



PR:000078760

syntaxin-binding protein 1 methylated 3 (human)

hSTXBP1/Me:3


"A syntaxin-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-180 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-180, MOD:00660." [IEDB_epitope:998822, PRO:DNx]


organism-modification



PR:000079783

syntaxin-binding protein 1 cysteinylated 3 (human)

hSTXBP1/Cyst:3


"A syntaxin-binding protein 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-180 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-180, MOD:00765." [IEDB_epitope:998821, PRO:DNx]


organism-modification



PR:000081599

syntaxin-binding protein 1 methylated 4 (human)

hSTXBP1/Me:4


"A syntaxin-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-354 of the amino acid sequence represented by UniProtKB:P61764. UniProtKB:P61764, Cys-354, MOD:00660." [IEDB_epitope:1018161, PRO:DNx]


organism-gene



PR:P61765

syntaxin-binding protein 1 (rat)

rSTXBP1


"A syntaxin-binding protein 1 that is encoded in the genome of rat." [OMA:P61765, PRO:DNx]


organism-sequence



PR:P61765-1

syntaxin-binding protein 1 isoform r1 (rat)

rSTXBP1/iso:r1


"A syntaxin-binding protein 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61765-1." [PRO:DNx, UniProtKB:P61765]


organism-sequence



PR:P61765-2

syntaxin-binding protein 1 isoform r2 (rat)

rSTXBP1/iso:r2


"A syntaxin-binding protein 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61765-2." [PRO:DNx, UniProtKB:P61765]


organism-gene



PR:Q07327

protein ROP (fruit fly)

fly-STXBP1


"A syntaxin-binding protein 1 that is encoded in the genome of fruit fly." [OMA:Q07327, PRO:HJD]


sequence



PR:000003322

syntaxin-binding protein 1 isoform 1

STXBP1/iso:1


"A syntaxin-binding protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O08599-1 or a 1:1 ortholog thereof." [PRO:HJD, UniProtKB:O08599-1]


organism-sequence



PR:O08599-1

syntaxin-binding protein 1 isoform 1 (mouse)

mSTXBP1/iso:1


"A syntaxin-binding protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:HJD]

Yes

organism-sequence



PR:P61764-1

syntaxin-binding protein 1 isoform 1 (human)

hSTXBP1/iso:1


"A syntaxin-binding protein 1 isoform 1 that is encoded in the genome of human." [PRO:HJD]


sequence



PR:000003323

syntaxin-binding protein 1 isoform 2

STXBP1/iso:2


"A syntaxin-binding protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O08599-2 or a 1:1 ortholog thereof." [PRO:HJD, UniProtKB:O08599-2]


organism-sequence



PR:O08599-2

syntaxin-binding protein 1 isoform 2 (mouse)

mSTXBP1/iso:2


"A syntaxin-binding protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:HJD]


organism-sequence



PR:P61764-2

syntaxin-binding protein 1 isoform 2 (human)

hSTXBP1/iso:2


"A syntaxin-binding protein 1 isoform 2 that is encoded in the genome of human." [PRO:HJD]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O08599 mSTXBP1 acts_upstream_of_or_withinGO:0007412 axon target recognition PMID:15182301
GO:0016188 synaptic vesicle maturation PMID:15145078
PR:O08599-1 mSTXBP1/iso:1 acts_upstream_of_or_withinGO:0032229 negative regulation of synaptic transmission, GABAergic PMID:17167098
located_inGO:0005739 mitochondrion PMID:14651853