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Protein Ontology report - lymphocyte antigen 96
PR:000003296 - http://purl.obolibrary.org/obo/PR_000003296
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003296   
  PRO namelymphocyte antigen 96 
  Synonyms
PRO-Short-label: EXACT:LY96
Gene-based: RELATED:ESOP1 | MD2
Other: EXACT:ESOP-1 | ly-96 | protein MD-2
  Definition"A protein that is a translation product of the human LY96 gene or a 1:1 ortholog thereof." [TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2890
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003296
lymphocyte antigen 96
LY96
"A protein that is a translation product of the human LY96 gene or a 1:1 ortholog thereof." [TLR:AMM]

Yes
organism-gene


PR:A0A1D5NZX9
lymphocyte antigen 96 (chicken)
chick-LY96
"A lymphocyte antigen 96 that is encoded in the genome of chicken." [OMA:A0A1D5NZX9, TLR:AMM]

Yes
organism-gene


PR:Q9JHF9
lymphocyte antigen 96 (mouse)
mLY96
"A lymphocyte antigen 96 that is encoded in the genome of mouse." [OMA:Q9JHF9, TLR:AMM]
Yes
organism-sequence


PR:Q9JHF9-1
lymphocyte antigen 96 isoform 1 (mouse)
mLY96/iso:1
"A lymphocyte antigen 96 isoform 1 that is encoded in the genome of mouse." [TLR:AMM]

organism-modification


PR:000027171
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
mLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160." [PMID:17803912, PRO:CNA]
Yes
Yes
organism-gene


PR:Q9Y6Y9
lymphocyte antigen 96 (human)
hLY96
"A lymphocyte antigen 96 that is encoded in the genome of human." [TLR:AMM, UniProtKB:Q9Y6Y9]

organism-sequence


PR:Q9Y6Y9-1
lymphocyte antigen 96 isoform 1 (human)
hLY96/iso:1
"A lymphocyte antigen 96 isoform 1 that is encoded in the genome of human." [TLR:AMM]

organism-modification


PR:000025786
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
hLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160." [PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
Yes
Yes
organism-sequence


PR:Q9Y6Y9-2
lymphocyte antigen 96 isoform h2 (human)
hLY96/iso:h2
"A lymphocyte antigen 96 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Y9-2." [PRO:DNx, UniProtKB:Q9Y6Y9]

organism-modification


PR:000048277
lymphocyte antigen 96, signal peptide removed form (human)
hLY96/SigPep-
"A lymphocyte antigen 96 (human) that has had the signal peptide removed. UniProtKB:Q9Y6Y9, 19-160." [PRO:DNx, Reactome:R-HSA-2201307]

organism-modification


PR:000025786
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
hLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160." [PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
Yes
Yes
sequence


PR:000003297
lymphocyte antigen 96 isoform 1
LY96/iso:1
"A lymphocyte antigen 96 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Y9-1 or a 1:1 ortholog thereof." [TLR:AMM]

organism-sequence


PR:Q9JHF9-1
lymphocyte antigen 96 isoform 1 (mouse)
mLY96/iso:1
"A lymphocyte antigen 96 isoform 1 that is encoded in the genome of mouse." [TLR:AMM]

organism-modification


PR:000027171
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
mLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160." [PMID:17803912, PRO:CNA]
Yes
Yes
organism-sequence


PR:Q9Y6Y9-1
lymphocyte antigen 96 isoform 1 (human)
hLY96/iso:1
"A lymphocyte antigen 96 isoform 1 that is encoded in the genome of human." [TLR:AMM]

organism-modification


PR:000025786
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
hLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160." [PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
Yes
Yes
modification


PR:000021940
lymphocyte antigen 96 isoform 1, signal peptide removed form
LY96/iso:1/SigPep-
"A lymphocyte antigen 96 isoform 1 that has had the signal peptide removed." [PRO:DAN]

modification


PR:000003298
lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form
LY96/iso:1/SigPep-/GlycoRes+
"A lymphocyte antigen 96 isoform 1, signal peptide removed form that includes at least one glycosylated residue." [PRO:CNA]

Yes
modification


PR:000003299
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1
LY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form that has been N-glycosylated at positions equivalent to Asn-26 and Asn-114 of the amino acid sequence represented by UniProtKB:Q9Y6Y9-1. Example: UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160." [PMID:11593030, PMID:17569869, PRO:CNA, PRO:DAN, TLR:AMM]

Yes
organism-modification


PR:000025786
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
hLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160." [PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
Yes
Yes
organism-modification


PR:000027171
lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)
mLY96/iso:1/SigPep-/NGlyco:1
"A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160." [PMID:17803912, PRO:CNA]
Yes
Yes
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LY96 forms found in complexes   

LY96 Component
 Complexes
PR:000003296 LY96 PR:000025784 MYD88:TIRAP:activated TLR4 receptor
PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex
PR:000036003 LY96:TLR4 complex
PR:000036076 activated TLR4 complex
PR:000003298 LY96/iso:1/SigPep-/GlycoRes+ PR:000036078 TIRAP:PIP2:activated TLR4 complex
PR:000003299 LY96/iso:1/SigPep-/NGlyco:1 PR:000025495 lipopolysaccharide receptor complex 1
PR:000025496 lipopolysaccharide receptor complex 2
PR:000025497 lipopolysaccharide receptor complex 3
PR:000025498 lipopolysaccharide receptor complex 4
PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1 PR:000025773 lipopolysaccharide receptor complex 3 (human)
PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
PR:000027218 pTIRAP:PIP2:activated TLR4 complex (human)
PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
PR:000028678 ticam2:activated TLR4 complex (human)
PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000036004 LY96:TLR4 complex (human)
PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human)
PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
PR:000036135 TIRAP:PIP2:activated TLR4 complex (human)
PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037479 lipopolysaccharide receptor complex 4 (human)
PR:000044684 activated TLR4 complex (human)
PR:000027171 mLY96/iso:1/SigPep-/NGlyco:1 PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)
PR:000027175 MYD88l:TIRAP:activated TLR4 receptor (mouse)
PR:000027187 IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse)
PR:000027196 TIRAP:PIP2:activated TLR4 (mouse)
PR:000027204 ticam2:activated TLR4 complex (mouse)
PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse)
PR:000027217 pTIRAP:PIP2:activated TLR4 complex (mouse)
PR:000027220 IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027221 pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027267 IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000028683 traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036005 LY96:TLR4 complex (mouse)
PR:000036077 activated TLR4 complex (mouse)
PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036095 K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036099 ikke:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036105 pel1:rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000037476 lipopolysaccharide receptor complex 3 (mouse)
PR:000037477 TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037478 pTIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037794 MD2:GB4:TLR4 complex (mouse)
PR:A0A1D5NZX9 chick-LY96 PR:000037473 LY96:TLR4 complex (chicken)
PR:000037474 activated TLR4 complex (chicken)
PR:000037475 MYD88:TIRAP:activated TLR4 receptor (chicken)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025786 hLY96/iso:1/SigPep-/NGlyco:1
UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160		 enablesGO:0001530 lipopolysaccharide binding PMID:17569869
GO:1990458 lipooligosaccharide binding PMID:19783674
located_inGO:0005615 extracellular space PMID:19783674
GO:0005615 extracellular space PMID:19783674
GO:0005886 plasma membrane Reactome:REACT_7660
PR:000027171 mLY96/iso:1/SigPep-/NGlyco:1
UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160		 enablesNOT GO:1990458 lipooligosaccharide binding PMID:19783674
located_inGO:0005615 extracellular space PMID:19783674
PR:Q9JHF9 mLY96 enablesGO:0005515 protein binding with PR:O35716 Cish1 PMID:19296467