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Protein Ontology report - insulin receptor-related receptor
PR:000003272 - http://purl.obolibrary.org/obo/PR_000003272
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003272   
  PRO nameinsulin receptor-related receptor 
  Synonyms
Other: EXACT:insulin receptor family
  Definition"A protein that has a core domain composition consisting of a Receptor L domain (Pfam:PF01030) followed by a Furin-like cysteine rich region (Pfam:PF00757) and a second copy of the Receptor L domain (Pfam:PF01030), two to four copies of the Fibronectin type 3 domain (Pfam:PF00041) and a copy of the Protein tyrosine kinase (Pfam:PF07714) domain at the C-terminus." [PRO:JAN] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification5                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000003272

insulin receptor-related receptor

CDK1


"A protein that has a core domain composition consisting of a Receptor L domain (Pfam:PF01030) followed by a Furin-like cysteine rich region (Pfam:PF00757) and a second copy of the Receptor L domain (Pfam:PF01030), two to four copies of the Fibronectin type 3 domain (Pfam:PF00041) and a copy of the Protein tyrosine kinase (Pfam:PF07714) domain at the C-terminus." [PRO:JAN]


gene



PR:000003273

insulin-like growth factor 1 receptor

IGF1R


"An insulin receptor-related receptor that is a translation product of the human IGF1R gene or a 1:1 ortholog thereof." [PRO:JAN]


organism-gene



PR:P08069

insulin-like growth factor 1 receptor (human)

hIGF1R


"An insulin-like growth factor 1 receptor that is encoded in the genome of human." [PRO:JAN, UniProtKB:P08069]


organism-sequence



PR:P08069-1

insulin-like growth factor 1 receptor isoform 1 (human)

hIGF1R/iso:1


"An insulin-like growth factor 1 receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000054420

insulin-like growth factor 1 receptor O-glycosylated 1 (human)

hIGF1R/OGlyco:1


"An insulin-like growth factor 1 receptor (human) that has been O-glycosylated at the residue equivalent to Thr-684 of the amino acid sequence represented by UniProtKB:P08069-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P08069-1, Thr-684, MOD:00005~GNO:G43417UB." [GlyGen:P08069-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000078845

insulin-like growth factor 1 receptor deaminated 1 (human)

hIGF1R/Deam:1


"An insulin-like growth factor 1 receptor (human) that has been deaminated on the residue at the position equivalent to Asn-314 of the amino acid sequence represented by UniProtKB:P08069. UniProtKB:P08069, Asn-314, MOD:00684." [IEDB_epitope:1570003, PRO:DNx]


organism-gene



PR:P24062

insulin-like growth factor 1 receptor (rat)

rIGF1R


"An insulin-like growth factor 1 receptor that is encoded in the genome of rat." [OMA:P24062, PRO:DNx]


organism-gene



PR:Q60751

insulin-like growth factor 1 receptor (mouse)

mIGF1R


"An insulin-like growth factor 1 receptor that is encoded in the genome of mouse." [OMA:Q60751, PRO:DNx]


organism-sequence



PR:Q60751-1

insulin-like growth factor 1 receptor isoform 1 (mouse)

mIGF1R/iso:1


"An insulin-like growth factor 1 receptor isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


sequence



PR:000003274

insulin-like growth factor 1 receptor isoform 1

IGF1R/iso:1


"An insulin-like growth factor 1 receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08069-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P08069-1

insulin-like growth factor 1 receptor isoform 1 (human)

hIGF1R/iso:1


"An insulin-like growth factor 1 receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:Q60751-1

insulin-like growth factor 1 receptor isoform 1 (mouse)

mIGF1R/iso:1


"An insulin-like growth factor 1 receptor isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000021922

insulin-like growth factor 1 receptor isoform 1, signal peptide removed form

IGF1R/iso:1/SigPep-


"An insulin-like growth factor 1 receptor isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000003276

insulin-like growth factor 1 receptor isoform 1 cleaved 1

IGF1R/iso:1/Clv:1


"An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the N-terminal mature chain." [PMID:8257688, PRO:JAN]


modification



PR:000003277

insulin-like growth factor 1 receptor isoform 1 cleaved 2

IGF1R/iso:1/Clv:2


"An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the C-terminal mature chain." [PRO:JAN]


modification



PR:000018802

insulin-like growth factor 1 receptor, signal peptide removed form

IGF1R/SigPep-


"An insulin-like growth factor 1 receptor that has had the signal peptide removed." [PRO:DNx]


modification



PR:000021922

insulin-like growth factor 1 receptor isoform 1, signal peptide removed form

IGF1R/iso:1/SigPep-


"An insulin-like growth factor 1 receptor isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000003276

insulin-like growth factor 1 receptor isoform 1 cleaved 1

IGF1R/iso:1/Clv:1


"An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the N-terminal mature chain." [PMID:8257688, PRO:JAN]


modification



PR:000003277

insulin-like growth factor 1 receptor isoform 1 cleaved 2

IGF1R/iso:1/Clv:2


"An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the C-terminal mature chain." [PRO:JAN]


modification



PR:000018803

insulin-like growth factor 1 receptor proteolytic cleavage product

IGF1R/ClvPrd


"An insulin-like growth factor 1 receptor that has been processed by proteolytic cleavage." [PRO:DNx]


modification



PR:000003276

insulin-like growth factor 1 receptor isoform 1 cleaved 1

IGF1R/iso:1/Clv:1


"An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the N-terminal mature chain." [PMID:8257688, PRO:JAN]


modification



PR:000003277

insulin-like growth factor 1 receptor isoform 1 cleaved 2

IGF1R/iso:1/Clv:2


"An insulin-like growth factor 1 receptor isoform 1, signal peptide removed form that has been subsequently processed to yield the C-terminal mature chain." [PRO:JAN]