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Protein Ontology report - 14-3-3 protein zeta/delta
PR:000003236 - http://purl.obolibrary.org/obo/PR_000003236
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003236   
  PRO name14-3-3 protein zeta/delta 
  Synonyms
PRO-Short-label: EXACT:YWHAZ
Other: EXACT:SEZ-2
RELATED:KCIP-1 | protein kinase C inhibitor protein 1
  Definition"A 14-3-3 protein that is a translation product of the human YWHAZ gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000003237 14-3-3 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003236

14-3-3 protein zeta/delta

YWHAZ


"A 14-3-3 protein that is a translation product of the human YWHAZ gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P29310

14-3-3 protein zeta (fruit fly)

fly-YWHAZ


"A 14-3-3 protein zeta/delta that is encoded in the genome of fruit fly." [PRO:CNA]


organism-sequence



PR:P29310-1

14-3-3 protein zeta isoform VI (fruit fly)

fly-YWHAZ/iso:VI


"A 14-3-3 protein zeta (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29310-1." [PRO:DNx, UniProtKB:P29310]


organism-sequence



PR:P29310-2

14-3-3 protein zeta isoform VI' (fruit fly)

fly-YWHAZ/iso:VI'


"A 14-3-3 protein zeta (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29310-2." [PRO:DNx, UniProtKB:P29310]


organism-sequence



PR:P29310-3

14-3-3 protein zeta isoform C (fruit fly)

fly-YWHAZ/iso:C


"A 14-3-3 protein zeta (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29310-3." [PRO:DNx, UniProtKB:P29310]


organism-gene



PR:P63101

14-3-3 protein zeta/delta (mouse)

mYWHAZ


"A 14-3-3 protein zeta/delta that is encoded in the genome of mouse." [OMA:P63101, PRO:CNA]


organism-sequence



PR:P63101-1

14-3-3 protein zeta/delta isoform 1 (mouse)

mYWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000036165

14-3-3 protein zeta/delta acetylated 1 (mouse)

mYWHAZ/Ac:1


"A 14-3-3 protein zeta/delta (mouse) that is N-terminal Met acetylated. UniProtKB:P63101, Met-1, MOD:00058." [TDR:8875]


organism-gene



PR:P63102

14-3-3 protein zeta/delta (rat)

rYWHAZ


"A 14-3-3 protein zeta/delta that is encoded in the genome of rat." [OMA:P63102, PRO:DNx]


organism-sequence



PR:P63102-1

14-3-3 protein zeta/delta isoform 1 (rat)

rYWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P63103

14-3-3 protein zeta/delta (cow)

cow-YWHAZ


"A 14-3-3 protein zeta/delta that is encoded in the genome of cow." [OMA:P63103, PRO:DNx]


organism-gene



PR:P63104

14-3-3 protein zeta/delta (human)

hYWHAZ


"A 14-3-3 protein zeta/delta that is encoded in the genome of human." [PRO:DNx]

Yes

Yes
organism-sequence



PR:P63104-1

14-3-3 protein zeta/delta isoform 1 (human)

hYWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P63104-2

14-3-3 protein zeta/delta isoform h2 (human)

hYWHAZ/iso:h2


"A 14-3-3 protein zeta/delta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63104-2." [PRO:DNx, UniProtKB:P63104]


organism-modification



PR:000036164

14-3-3 protein zeta/delta acetylated 1 (human)

hYWHAZ/Ac:1


"A 14-3-3 protein zeta/delta (human) that is N-terminal Met acetylated. Example: UniProtKB:P63104-1, Met-1, MOD:00058." [TDR:2016]


organism-modification



PR:000044508

14-3-3 protein zeta/delta phosphorylated 1 (human)

hYWHAZ/Phos:1


"A 14-3-3 protein zeta/delta (human) that has been phosphorylated on the residue at the position equivalent to Ser-184 of the amino acid sequence represented by UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Ser-184, MOD:00046." [PMID:15696159, PRO:CNA]

Yes

organism-modification



PR:000044509

14-3-3 protein zeta/delta unphosphorylated 1 (human)

hYWHAZ/UnPhos:1


"A 14-3-3 protein zeta/delta (human) that lacks phosphorylation on the residue at the position equivalent to Ser-184 of the amino acid sequence represented by UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Ser-184, PR:000026291." [PMID:15696159, PRO:CNA]

Yes

organism-modification



PR:000045851

14-3-3 protein zeta/delta phosphorylated 2 (human)

hYWHAZ/Phos:2


"A 14-3-3 protein zeta/delta (human) that has been phosphorylated on the residue at the position equivalent to Ser-58 of the amino acid sequence represented by UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Ser-58, MOD:00046." [iPTMnet:P63104, PMID:11956222, PMID:12861023, PMID:16376338]


organism-modification



PR:000069598

14-3-3 protein zeta/delta methylated 1 (human)

hYWHAZ/Me:1


"A 14-3-3 protein zeta/delta (human) that has been methylated on the residue at the position equivalent to Cys-25 of the amino acid sequence represented by UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Cys-25, MOD:00660." [IEDB_epitope:1060806, PRO:DNx]


organism-modification



PR:000073672

14-3-3 protein zeta/delta methylated 2 (human)

hYWHAZ/Me:2


"A 14-3-3 protein zeta/delta (human) that has been methylated on the residue at the position equivalent to Cys-94 of the amino acid sequence represented by UniProtKB:P63104-1. Example: UniProtKB:P63104-1, Cys-94, MOD:00660." [IEDB_epitope:1053659, PRO:DNx]


organism-gene



PR:Q5ZKC9

14-3-3 protein zeta (chicken)

chick-YWHAZ


"A 14-3-3 protein zeta/delta that is encoded in the genome of chicken." [OMA:Q5ZKC9, PRO:DNx]


organism-sequence



PR:Q5ZKC9-1

14-3-3 protein zeta isoform 1 (chicken)

chick-YWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


sequence



PR:000040069

14-3-3 protein zeta/delta isoform 1

YWHAZ/iso:1


"A 14-3-3 protein zeta/delta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63104-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P63101-1

14-3-3 protein zeta/delta isoform 1 (mouse)

mYWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P63102-1

14-3-3 protein zeta/delta isoform 1 (rat)

rYWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P63104-1

14-3-3 protein zeta/delta isoform 1 (human)

hYWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q5ZKC9-1

14-3-3 protein zeta isoform 1 (chicken)

chick-YWHAZ/iso:1


"A 14-3-3 protein zeta/delta isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


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YWHAZ forms found in complexes   

YWHAZ Component
Complexes
PR:P63104 hYWHAZ PR:000028429 GPIb-IX-V:vWF:14-3-3-zeta:p85 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044508 hYWHAZ/Phos:1
Example: UniProtKB:P63104-1, Ser-184, MOD:00046
enablesdecreased GO:0005515 protein binding with PR:000044506 hABL1/Phos:1 PMID:15696159
PR:000044509 hYWHAZ/UnPhos:1
Example: UniProtKB:P63104-1, Ser-184, PR:000026291
enablesGO:0005515 protein binding with PR:000044506 hABL1/Phos:1 PMID:15696159
PR:P63104 hYWHAZ enablesGO:0005515 protein binding with PR:000044814 Bc phosphorylated 1 (human) PMID:10477722