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Protein Ontology report - mitogen-activated protein kinase kinase kinase 1
PR:000003215 - http://purl.obolibrary.org/obo/PR_000003215
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003215   
  PRO namemitogen-activated protein kinase kinase kinase 1 
  Synonyms
PRO-Short-label: EXACT:MAP3K1
Gene-based: RELATED:MAPKKK1 | MEKK | MEKK1
Other: EXACT:MAPK/ERK kinase kinase 1 | MEK kinase 1 | MEKK 1
  Definition"A protein that is a translation product of the human MAP3K1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification4                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2069
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003215
mitogen-activated protein kinase kinase kinase 1
MAP3K1
"A protein that is a translation product of the human MAP3K1 gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:P53349
mitogen-activated protein kinase kinase kinase 1 (mouse)
mMAP3K1
"A mitogen-activated protein kinase kinase kinase 1 that is encoded in the genome of mouse." [OMA:P53349, PRO:DNx]

organism-gene


PR:Q13233
mitogen-activated protein kinase kinase kinase 1 (human)
hMAP3K1
"A mitogen-activated protein kinase kinase kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13233]

organism-sequence


PR:Q13233-1
mitogen-activated protein kinase kinase kinase 1 isoform 1 (human)
hMAP3K1/iso:1
"A mitogen-activated protein kinase kinase kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-modification


PR:000048302
mitogen-activated protein kinase kinase kinase 1, initiator methionine removed form (human)
hMAP3K1/InitMet-
"A mitogen-activated protein kinase kinase kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q13233, 2-1512." [PRO:DNx, Reactome:R-HSA-166866]

organism-modification


PR:000048303
mitogen-activated protein kinase kinase kinase 1, initiator methionine removed phosphorylated 1 (human)
hMAP3K1/InitMet-/Phos:1
"A mitogen-activated protein kinase kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 1400 and 1412 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, 2-1512, Thr-1400/Thr-1412, MOD:00047." [PRO:DNx, Reactome:R-HSA-2685607]

organism-modification


PR:000072392
mitogen-activated protein kinase kinase kinase 1 deaminated 1 (human)
hMAP3K1/Deam:1
"A mitogen-activated protein kinase kinase kinase 1 (human) that has been deaminated on the residue at the position equivalent to Gln-681 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, Gln-681, MOD:00685." [IEDB_epitope:1362915, PRO:DNx]

organism-modification


PR:000072822
mitogen-activated protein kinase kinase kinase 1 phosphorylated 1 (human)
hMAP3K1/Phos:1
"A mitogen-activated protein kinase kinase kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1478 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, Ser-1478, MOD:00046." [IEDB_epitope:1349842, PRO:DNx]

organism-modification


PR:000075839
mitogen-activated protein kinase kinase kinase 1 cysteinylated 1 (human)
hMAP3K1/Cyst:1
"A mitogen-activated protein kinase kinase kinase 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-1257 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, Cys-1257, MOD:00765." [IEDB_epitope:1571895, PRO:DNx]

organism-modification


PR:000080181
mitogen-activated protein kinase kinase kinase 1 cysteinylated 2 (human)
hMAP3K1/Cyst:2
"A mitogen-activated protein kinase kinase kinase 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-643 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, Cys-643, MOD:00765." [IEDB_epitope:1587863, PRO:DNx]

organism-modification


PR:000082226
mitogen-activated protein kinase kinase kinase 1 methylated 1 (human)
hMAP3K1/Me:1
"A mitogen-activated protein kinase kinase kinase 1 (human) that has been methylated on the residue at the position equivalent to Cys-643 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, Cys-643, MOD:00660." [IEDB_epitope:1003836, PRO:DNx]

organism-modification


PR:000082637
mitogen-activated protein kinase kinase kinase 1 phosphorylated 2 (human)
hMAP3K1/Phos:2
"A mitogen-activated protein kinase kinase kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1472 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, Ser-1472, MOD:00046." [IEDB_epitope:1350220, PRO:DNx]

organism-gene


PR:Q62925
mitogen-activated protein kinase kinase kinase 1 (rat)
rMAP3K1
"A mitogen-activated protein kinase kinase kinase 1 that is encoded in the genome of rat." [OMA:Q62925, PRO:DNx]

sequence


PR:000003216
mitogen-activated protein kinase kinase kinase 1 isoform 1
MAP3K1/iso:1
"A mitogen-activated protein kinase kinase kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13233-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:Q13233-1
mitogen-activated protein kinase kinase kinase 1 isoform 1 (human)
hMAP3K1/iso:1
"A mitogen-activated protein kinase kinase kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]

modification


PR:000003218
mitogen-activated protein kinase kinase kinase 1 isoform 1 phosphorylated form
MAP3K1/iso:1/PhosRes+
"A mitogen-activated protein kinase kinase kinase 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]

modification


PR:000003219
mitogen-activated protein kinase kinase kinase 1 isoform 1 phosphorylated 1
MAP3K1/iso:1/Phos:1
"A mitogen-activated protein kinase kinase kinase 1 isoform 1 phosphorylated form that is the active form." [PRO:CNA]

modification


PR:000026704
mitogen-activated protein kinase kinase kinase 1 isoform 1, initiator methionine removed form
MAP3K1/iso:1/InitMet-
"A mitogen-activated protein kinase kinase kinase 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]

modification


PR:000018793
mitogen-activated protein kinase kinase kinase 1, initiator methionine removed form
MAP3K1/InitMet-
"A mitogen-activated protein kinase kinase kinase 1 that has had the initiator methionine removed." [PRO:DNx]

modification


PR:000026704
mitogen-activated protein kinase kinase kinase 1 isoform 1, initiator methionine removed form
MAP3K1/iso:1/InitMet-
"A mitogen-activated protein kinase kinase kinase 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000048302
mitogen-activated protein kinase kinase kinase 1, initiator methionine removed form (human)
hMAP3K1/InitMet-
"A mitogen-activated protein kinase kinase kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q13233, 2-1512." [PRO:DNx, Reactome:R-HSA-166866]

organism-modification


PR:000048303
mitogen-activated protein kinase kinase kinase 1, initiator methionine removed phosphorylated 1 (human)
hMAP3K1/InitMet-/Phos:1
"A mitogen-activated protein kinase kinase kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 1400 and 1412 of the amino acid sequence represented by UniProtKB:Q13233. UniProtKB:Q13233, 2-1512, Thr-1400/Thr-1412, MOD:00047." [PRO:DNx, Reactome:R-HSA-2685607]