|
|
 |
 |
|  |  |
 |  |  |  |  |  |  |
gene
 |


|
 PR:000003178 |
   shc-transforming protein 1
 |
   SHC1
 |
  "An shc-transforming protein that is a translation product of the human SHC1 gene or a 1:1 ortholog thereof." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:P29353 |
   SHC-transforming protein 1 (human)
 |
   hSHC1
 |
  "An shc-transforming protein 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P29353]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-1 |
   SHC-transforming protein 1 isoform p66Shc (human)
 |
   hSHC1/iso:p66Shc
 |
  "An shc-transforming protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000062560 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p66Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000085896 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)
 |
   hSHC1/iso:p66Shc/Phos:2
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-2 |
   SHC-transforming protein 1 isoform p52Shc (human)
 |
   hSHC1/iso:p52Shc
 |
  "An shc-transforming protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061010 |
   SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p52Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-3 |
   SHC-transforming protein 1 isoform p46Shc (human)
 |
   hSHC1/iso:p46Shc
 |
  "An shc-transforming protein 1 isoform 3 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-5 |
   SHC-transforming protein 1 isoform h5 (human)
 |
   hSHC1/iso:h5
 |
  "An SHC-transforming protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29353-5." [PRO:DNx, UniProtKB:P29353]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-6 |
   SHC-transforming protein 1 isoform h6 (human)
 |
   hSHC1/iso:h6
 |
  "An SHC-transforming protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29353-6." [PRO:DNx, UniProtKB:P29353]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-7 |
   SHC-transforming protein 1 isoform h7 (human)
 |
   hSHC1/iso:h7
 |
  "An SHC-transforming protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29353-7." [PRO:DNx, UniProtKB:P29353]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-modification
 |


|
 PR:000049233 |
   SHC-transforming protein 1 phosphotyrosine form (human)
 |
   hSHC1/PhosTyr+
 |
  "An SHC-transforming protein 1 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P29353, MOD:00048." [PRO:DNx, Reactome:R-HSA-162568]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000049230 |
   SHC-transforming protein 1 phosphorylated 1 (human)
 |
   hSHC1/Phos:1
 |
  "An SHC-transforming protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 349 and 350 of the amino acid sequence represented by UniProtKB:P29353. UniProtKB:P29353, Tyr-349/Tyr-350, MOD:00048." [PRO:DNx, Reactome:R-HSA-180276]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000049231 |
   SHC-transforming protein 1 phosphorylated 2 (human)
 |
   hSHC1/Phos:2
 |
  "An SHC-transforming protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 349, 350 and 427 of the amino acid sequence represented by UniProtKB:P29353. UniProtKB:P29353, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-912321]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000049232 |
   SHC-transforming protein 1 phosphorylated 3 (human)
 |
   hSHC1/Phos:3
 |
  "An SHC-transforming protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-427 of the amino acid sequence represented by UniProtKB:P29353. UniProtKB:P29353, Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-74684]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061010 |
   SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p52Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000062560 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p66Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000085896 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)
 |
   hSHC1/iso:p66Shc/Phos:2
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:P98083 |
   SHC-transforming protein 1 (mouse)
 |
   mSHC1
 |
  "An shc-transforming protein 1 that is encoded in the genome of mouse." [OMA:P98083, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P98083-1 |
   SHC-transforming protein 1 isoform p66Shc (mouse)
 |
   mSHC1/iso:p66Shc
 |
  "An shc-transforming protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P98083-2 |
   SHC-transforming protein 1 isoform p52Shc (mouse)
 |
   mSHC1/iso:p52Shc
 |
  "An shc-transforming protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P98083-3 |
   SHC-transforming protein 1 isoform p47Shc (mouse)
 |
   mSHC1/iso:p47Shc
 |
  "An shc-transforming protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |
organism-gene
 |


|
 PR:Q5M824 |
   SHC-transforming protein 1 (rat)
 |
   rSHC1
 |
  "An shc-transforming protein 1 that is encoded in the genome of rat." [OMA:Q5M824, PRO:DNx]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |
sequence
 |


|
 PR:000003182 |
   shc-transforming protein 1 isoform 1
 |
   SHC1/iso:1
 |
  "An shc-transforming protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98083-1 or a 1:1 ortholog thereof." [PMID:11948181, PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-1 |
   SHC-transforming protein 1 isoform p66Shc (human)
 |
   hSHC1/iso:p66Shc
 |
  "An shc-transforming protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000062560 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p66Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000085896 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)
 |
   hSHC1/iso:p66Shc/Phos:2
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P98083-1 |
   SHC-transforming protein 1 isoform p66Shc (mouse)
 |
   mSHC1/iso:p66Shc
 |
  "An shc-transforming protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
modification
 |


|
 PR:000003186 |
   shc-transforming protein 1 isoform 1 phosphorylated form
 |
   SHC1/iso:1/PhosRes+
 |
  "An shc-transforming protein 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
modification
 |


|
 PR:000003187 |
   shc-transforming protein 1 isoform 1 phosphorylated 1
 |
   SHC1/iso:1/Phos:1
 |
  "An shc-transforming protein 1 isoform 1 phosphorylated form in which the phosphorylation occurs at Ser and Tyr residues by the action of activated TGF beta receptor type 1." [PID:SHC, PMID:17673906]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000062560 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p66Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000085896 |
   SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)
 |
   hSHC1/iso:p66Shc/Phos:2
 |
  "An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |
sequence
 |


|
 PR:000003183 |
   shc-transforming protein 1 isoform 2
 |
   SHC1/iso:2
 |
  "An shc-transforming protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98083-2 or a 1:1 ortholog thereof." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-2 |
   SHC-transforming protein 1 isoform p52Shc (human)
 |
   hSHC1/iso:p52Shc
 |
  "An shc-transforming protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061010 |
   SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p52Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P98083-2 |
   SHC-transforming protein 1 isoform p52Shc (mouse)
 |
   mSHC1/iso:p52Shc
 |
  "An shc-transforming protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
modification
 |


|
 PR:000003189 |
   shc-transforming protein 1 isoform 2 phosphorylated form
 |
   SHC1/iso:2/PhosRes+
 |
  "An shc-transforming protein 1 isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
modification
 |


|
 PR:000003190 |
   shc-transforming protein 1 isoform 2 phosphorylated 1
 |
   SHC1/iso:2/Phos:1
 |
  "An shc-transforming protein 1 isoform 2 phosphorylated form in which the phosphorylation occurs at Ser and Tyr residues by the action of activated TGF beta receptor type 1." [PID:SHC, PMID:17673906]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |  |  |
 |
organism-modification
 |


|
 PR:000061010 |
   SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)
 |
   hSHC1/iso:p52Shc/Phos:1
 |
  "An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]
 |

| 
|
|
|
 |
 |
|  |  |  |  |
 |  |  |  |  |
sequence
 |


|
 PR:000003184 |
   shc-transforming protein 1 isoform 3
 |
   SHC1/iso:3
 |
  "An shc-transforming protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98083-3 or a 1:1 ortholog thereof." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P29353-3 |
   SHC-transforming protein 1 isoform p46Shc (human)
 |
   hSHC1/iso:p46Shc
 |
  "An shc-transforming protein 1 isoform 3 that is encoded in the genome of human." [PRO:CNA]
 |

| 
|
|
|
 |
 |
|  |  |  |  |  |  |
 |  |  |
organism-sequence
 |


|
 PR:P98083-3 |
   SHC-transforming protein 1 isoform p47Shc (mouse)
 |
   mSHC1/iso:p47Shc
 |
  "An shc-transforming protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]
 |

| 
|
|
|