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Protein Ontology report - shc-transforming protein 1
PR:000003178 - http://purl.obolibrary.org/obo/PR_000003178
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003178   
  PRO nameshc-transforming protein 1 
  Synonyms
PRO-Short-label: EXACT:SHC1
Gene-based: RELATED:SHC | SHCA
Other: EXACT:SH2 domain protein C1 | src homology 2 domain-containing-transforming protein C1
RELATED:SHC-transforming protein 3 | SHC-transforming protein A
  Definition"An shc-transforming protein that is a translation product of the human SHC1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000003177 shc-transforming protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 9                                        
         Modification4                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003178

shc-transforming protein 1

SHC1


"An shc-transforming protein that is a translation product of the human SHC1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P29353

SHC-transforming protein 1 (human)

hSHC1


"An shc-transforming protein 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P29353]


organism-sequence



PR:P29353-1

SHC-transforming protein 1 isoform p66Shc (human)

hSHC1/iso:p66Shc


"An shc-transforming protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000062560

SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)

hSHC1/iso:p66Shc/Phos:1


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]


organism-modification



PR:000085896

SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)

hSHC1/iso:p66Shc/Phos:2


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]


organism-sequence



PR:P29353-2

SHC-transforming protein 1 isoform p52Shc (human)

hSHC1/iso:p52Shc


"An shc-transforming protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000061010

SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)

hSHC1/iso:p52Shc/Phos:1


"An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]


organism-sequence



PR:P29353-3

SHC-transforming protein 1 isoform p46Shc (human)

hSHC1/iso:p46Shc


"An shc-transforming protein 1 isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P29353-5

SHC-transforming protein 1 isoform h5 (human)

hSHC1/iso:h5


"An SHC-transforming protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29353-5." [PRO:DNx, UniProtKB:P29353]


organism-sequence



PR:P29353-6

SHC-transforming protein 1 isoform h6 (human)

hSHC1/iso:h6


"An SHC-transforming protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29353-6." [PRO:DNx, UniProtKB:P29353]


organism-sequence



PR:P29353-7

SHC-transforming protein 1 isoform h7 (human)

hSHC1/iso:h7


"An SHC-transforming protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29353-7." [PRO:DNx, UniProtKB:P29353]


organism-modification



PR:000049233

SHC-transforming protein 1 phosphotyrosine form (human)

hSHC1/PhosTyr+


"An SHC-transforming protein 1 (human) that includes at least one phosphorylated tyrosine. UniProtKB:P29353, MOD:00048." [PRO:DNx, Reactome:R-HSA-162568]


organism-modification



PR:000049230

SHC-transforming protein 1 phosphorylated 1 (human)

hSHC1/Phos:1


"An SHC-transforming protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 349 and 350 of the amino acid sequence represented by UniProtKB:P29353. UniProtKB:P29353, Tyr-349/Tyr-350, MOD:00048." [PRO:DNx, Reactome:R-HSA-180276]


organism-modification



PR:000049231

SHC-transforming protein 1 phosphorylated 2 (human)

hSHC1/Phos:2


"An SHC-transforming protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 349, 350 and 427 of the amino acid sequence represented by UniProtKB:P29353. UniProtKB:P29353, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-912321]


organism-modification



PR:000049232

SHC-transforming protein 1 phosphorylated 3 (human)

hSHC1/Phos:3


"An SHC-transforming protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-427 of the amino acid sequence represented by UniProtKB:P29353. UniProtKB:P29353, Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-74684]


organism-modification



PR:000061010

SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)

hSHC1/iso:p52Shc/Phos:1


"An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]


organism-modification



PR:000062560

SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)

hSHC1/iso:p66Shc/Phos:1


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]


organism-modification



PR:000085896

SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)

hSHC1/iso:p66Shc/Phos:2


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]


organism-gene



PR:P98083

SHC-transforming protein 1 (mouse)

mSHC1


"An shc-transforming protein 1 that is encoded in the genome of mouse." [OMA:P98083, PRO:DNx]


organism-sequence



PR:P98083-1

SHC-transforming protein 1 isoform p66Shc (mouse)

mSHC1/iso:p66Shc


"An shc-transforming protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P98083-2

SHC-transforming protein 1 isoform p52Shc (mouse)

mSHC1/iso:p52Shc


"An shc-transforming protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P98083-3

SHC-transforming protein 1 isoform p47Shc (mouse)

mSHC1/iso:p47Shc


"An shc-transforming protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:Q5M824

SHC-transforming protein 1 (rat)

rSHC1


"An shc-transforming protein 1 that is encoded in the genome of rat." [OMA:Q5M824, PRO:DNx]


sequence



PR:000003182

shc-transforming protein 1 isoform 1

SHC1/iso:1


"An shc-transforming protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98083-1 or a 1:1 ortholog thereof." [PMID:11948181, PRO:CNA]


organism-sequence



PR:P29353-1

SHC-transforming protein 1 isoform p66Shc (human)

hSHC1/iso:p66Shc


"An shc-transforming protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000062560

SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)

hSHC1/iso:p66Shc/Phos:1


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]


organism-modification



PR:000085896

SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)

hSHC1/iso:p66Shc/Phos:2


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]


organism-sequence



PR:P98083-1

SHC-transforming protein 1 isoform p66Shc (mouse)

mSHC1/iso:p66Shc


"An shc-transforming protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000003186

shc-transforming protein 1 isoform 1 phosphorylated form

SHC1/iso:1/PhosRes+


"An shc-transforming protein 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003187

shc-transforming protein 1 isoform 1 phosphorylated 1

SHC1/iso:1/Phos:1


"An shc-transforming protein 1 isoform 1 phosphorylated form in which the phosphorylation occurs at Ser and Tyr residues by the action of activated TGF beta receptor type 1." [PID:SHC, PMID:17673906]


organism-modification



PR:000062560

SHC-transforming protein 1 isoform p66Shc phosphorylated 1 (human)

hSHC1/iso:p66Shc/Phos:1


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Ser-139, Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Ser-139, MOD:00046|Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-8934452]


organism-modification



PR:000085896

SHC-transforming protein 1 isoform p66Shc phosphorylated 2 (human)

hSHC1/iso:p66Shc/Phos:2


"An SHC-transforming protein 1 isoform p66Shc (human) that has been phosphorylated on the residues at the positions equivalent to Tyr-349, Tyr-350, and Tyr-427 of the amino acid sequence represented by UniProtKB:P29353-1. UniProtKB:P29353-1, Tyr-349/Tyr-350/Tyr-427, MOD:00048." [PRO:DNx, Reactome:R-HSA-2404176]


sequence



PR:000003183

shc-transforming protein 1 isoform 2

SHC1/iso:2


"An shc-transforming protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98083-2 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P29353-2

SHC-transforming protein 1 isoform p52Shc (human)

hSHC1/iso:p52Shc


"An shc-transforming protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000061010

SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)

hSHC1/iso:p52Shc/Phos:1


"An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]


organism-sequence



PR:P98083-2

SHC-transforming protein 1 isoform p52Shc (mouse)

mSHC1/iso:p52Shc


"An shc-transforming protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000003189

shc-transforming protein 1 isoform 2 phosphorylated form

SHC1/iso:2/PhosRes+


"An shc-transforming protein 1 isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003190

shc-transforming protein 1 isoform 2 phosphorylated 1

SHC1/iso:2/Phos:1


"An shc-transforming protein 1 isoform 2 phosphorylated form in which the phosphorylation occurs at Ser and Tyr residues by the action of activated TGF beta receptor type 1." [PID:SHC, PMID:17673906]


organism-modification



PR:000061010

SHC-transforming protein 1 isoform p52Shc phosphorylated 1 (human)

hSHC1/iso:p52Shc/Phos:1


"An SHC-transforming protein 1 isoform p52Shc (human) that has been phosphorylated on the residue at the position equivalent to Tyr-317 of the amino acid sequence represented by UniProtKB:P29353-2. UniProtKB:P29353-2, Tyr-317, MOD:00048." [PRO:DNx, Reactome:R-HSA-8851895]


sequence



PR:000003184

shc-transforming protein 1 isoform 3

SHC1/iso:3


"An shc-transforming protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P98083-3 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P29353-3

SHC-transforming protein 1 isoform p46Shc (human)

hSHC1/iso:p46Shc


"An shc-transforming protein 1 isoform 3 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P98083-3

SHC-transforming protein 1 isoform p47Shc (mouse)

mSHC1/iso:p47Shc


"An shc-transforming protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]