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Protein Ontology report - E3 ubiquitin-protein ligase pellino homolog 1
PR:000003141 - http://purl.obolibrary.org/obo/PR_000003141
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000003141   
  PRO nameE3 ubiquitin-protein ligase pellino homolog 1 
  Synonyms
PRO-Short-label: EXACT:PELI1
Gene-based: RELATED:PRISM
Other: EXACT:pellino-1 | pellino-related intracellular-signaling molecule | RING-type E3 ubiquitin transferase pellino homolog 1
  Definition"A protein pellino that is a translation product of the human PELI1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000003140 protein pellino
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003141

E3 ubiquitin-protein ligase pellino homolog 1

PELI1


"A protein pellino that is a translation product of the human PELI1 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q8C669

E3 ubiquitin-protein ligase pellino homolog 1 (mouse)

mPELI1


"An E3 ubiquitin-protein ligase pellino homolog 1 that is encoded in the genome of mouse." [OMA:Q8C669, PRO:CNA]


Yes
organism-sequence



PR:Q8C669-1

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 (mouse)

mPELI1/iso:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:Q96FA3

E3 ubiquitin-protein ligase pellino homolog 1 (human)

hPELI1


"An E3 ubiquitin-protein ligase pellino homolog 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96FA3]


organism-sequence



PR:Q96FA3-1

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 (human)

hPELI1/iso:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000027047

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1 (human)

hPELI1/iso:1/Phos:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1 in human." [PMID:19264966, PRO:CNA]


organism-modification



PR:000063871

E3 ubiquitin-protein ligase pellino homolog 1 phosphorylated form (human)

hPELI1/PhosRes+


"An E3 ubiquitin-protein ligase pellino homolog 1 (human) that includes at least one phosphorylated residue. UniProtKB:Q96FA3, MOD:00696." [PRO:DNx, Reactome:R-HSA-450815]


organism-modification



PR:000064634

E3 ubiquitin-protein ligase pellino homolog 1 phosphorylated 1 (human)

hPELI1/Phos:1


"An E3 ubiquitin-protein ligase pellino homolog 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-39 of the amino acid sequence represented by UniProtKB:Q96FA3. UniProtKB:Q96FA3, Ser-39, MOD:00046." [IEDB_epitope:611631, PRO:DNx]


organism-modification



PR:000075404

E3 ubiquitin-protein ligase pellino homolog 1 methylated 1 (human)

hPELI1/Me:1


"An E3 ubiquitin-protein ligase pellino homolog 1 (human) that has been methylated on the residue at the position equivalent to Cys-61 of the amino acid sequence represented by UniProtKB:Q96FA3. UniProtKB:Q96FA3, Cys-61, MOD:00660." [IEDB_epitope:1004337, PRO:DNx]


organism-modification



PR:000075594

E3 ubiquitin-protein ligase pellino homolog 1 methylated 2 (human)

hPELI1/Me:2


"An E3 ubiquitin-protein ligase pellino homolog 1 (human) that has been methylated on the residue at the position equivalent to Cys-282 of the amino acid sequence represented by UniProtKB:Q96FA3. UniProtKB:Q96FA3, Cys-282, MOD:00660." [IEDB_epitope:1044348, PRO:DNx]


sequence



PR:000003142

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1

PELI1/iso:1


"An E3 ubiquitin-protein ligase pellino homolog 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8C669-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q8C669-1

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 (mouse)

mPELI1/iso:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:Q96FA3-1

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 (human)

hPELI1/iso:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000027047

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1 (human)

hPELI1/iso:1/Phos:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1 in human." [PMID:19264966, PRO:CNA]


modification



PR:000003144

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated form

PELI1/iso:1/PhosRes+


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003145

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1

PELI1/iso:1/Phos:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated form in which the phosphorylation occurs at the seven residues whose phosphorylation are critical for activation. Five of these residues are located in the region of antiparallel beta-sheet, termed the wing; whereas the other two are just N-terminal to the RING-like domain that carries the E3 ligase activity." [PMID:19264966, TLR:AMM]


organism-modification



PR:000027047

E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1 (human)

hPELI1/iso:1/Phos:1


"An E3 ubiquitin-protein ligase pellino homolog 1 isoform 1 phosphorylated 1 in human." [PMID:19264966, PRO:CNA]


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PELI1 forms found in complexes   

PELI1 Component
Complexes
PR:Q8C669 mPELI1 PR:000036105 pel1:rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)