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Protein Ontology report - Bcl-2-binding component 3
PR:000003124 - http://purl.obolibrary.org/obo/PR_000003124
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003124   
  PRO nameBcl-2-binding component 3 
  Synonyms
PRO-Short-label: EXACT:BBC3
Other: EXACT:JFY-1 | p53 up-regulated modulator of apoptosis
RELATED:PUMA
  Definition"A protein that is a translation product of the human BBC3 gene or a 1:1 ortholog thereof." [PRO:JAN] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 1                                        
         Sequence4                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003124
Bcl-2-binding component 3
BBC3
"A protein that is a translation product of the human BBC3 gene or a 1:1 ortholog thereof." [PRO:JAN]

organism-gene


PR:000030023
Bcl-2-binding component 3 (human)
hBBC3
"A Bcl-2-binding component 3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96PG8]

organism-seqgroup


PR:Q96PG8
Bcl-2-binding component 3 isoforms 4/3 (human)
hBBC3/iso:[4/3]
"A Bcl-2-binding component 3 (human), isoforms 4 and 3." [PRO:DAN, UniProtKB:Q96PG8]





PR:Q96PG8-1
Bcl-2-binding component 3 isoform 3 (human)










PR:Q96PG8-2
Bcl-2-binding component 3 isoform 4 (human)






organism-sequence


PR:Q96PG8-1
Bcl-2-binding component 3 isoform 3 (human)
hBBC3/iso:3
"A Bcl-2-binding component 3 isoform 3 that is encoded in the genome of human." [PRO:JAN]

organism-sequence


PR:Q96PG8-2
Bcl-2-binding component 3 isoform 4 (human)
hBBC3/iso:4
"A Bcl-2-binding component 3 isoform 4 that is encoded in the genome of human." [PRO:JAN]

organism-seqgroup


PR:Q9BXH1
Bcl-2-binding component 3 isoforms 1/2 (human)
hBBC3/iso:[1/2]
"A Bcl-2-binding component 3 (human), isoforms 1 and 2." [PRO:DAN, UniProtKB:Q9BXH1]





PR:Q9BXH1-1
Bcl-2-binding component 3 isoform 1 (human)










PR:Q9BXH1-2
Bcl-2-binding component 3 isoform 2 (human)






organism-sequence


PR:Q9BXH1-1
Bcl-2-binding component 3 isoform 1 (human)
hBBC3/iso:1
"A Bcl-2-binding component 3 isoform 1 that is encoded in the genome of human." [PRO:JAN]
Yes
organism-sequence


PR:Q9BXH1-2
Bcl-2-binding component 3 isoform 2 (human)
hBBC3/iso:2
"A Bcl-2-binding component 3 isoform 2 that is encoded in the genome of human." [PRO:JAN]

sequence


PR:000003125
Bcl-2-binding component 3 isoform 1
BBC3/iso:1
"A Bcl-2-binding component 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXH1-1 or a 1:1 ortholog thereof." [PMID:11463391, PMID:11463392, PRO:JAN]

organism-sequence


PR:Q99ML1-1
Bcl-2-binding component 3 isoform 1 (mouse)
mBBC3/iso:1
"A Bcl-2-binding component 3 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
Yes
organism-sequence


PR:Q9BXH1-1
Bcl-2-binding component 3 isoform 1 (human)
hBBC3/iso:1
"A Bcl-2-binding component 3 isoform 1 that is encoded in the genome of human." [PRO:JAN]
Yes
sequence


PR:000003126
Bcl-2-binding component 3 isoform 2
BBC3/iso:2
"A Bcl-2-binding component 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BXH1-2 or a 1:1 ortholog thereof." [PMID:11463392, PRO:JAN]

organism-sequence


PR:Q9BXH1-2
Bcl-2-binding component 3 isoform 2 (human)
hBBC3/iso:2
"A Bcl-2-binding component 3 isoform 2 that is encoded in the genome of human." [PRO:JAN]

sequence


PR:000030106
Bcl-2-binding component 3 isoform 4
BBC3/iso:4
"A Bcl-2-binding component 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PG8-2 or a 1:1 ortholog thereof." [PMID:11463392, PRO:JAN]

organism-sequence


PR:Q96PG8-2
Bcl-2-binding component 3 isoform 4 (human)
hBBC3/iso:4
"A Bcl-2-binding component 3 isoform 4 that is encoded in the genome of human." [PRO:JAN]

sequence


PR:000032603
Bcl-2-binding component 3 isoform 3
BBC3/iso:3
"A Bcl-2-binding component 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96PG8-1 or a 1:1 ortholog thereof." [PMID:11463391, PMID:11463392, PRO:JAN]

organism-sequence


PR:Q96PG8-1
Bcl-2-binding component 3 isoform 3 (human)
hBBC3/iso:3
"A Bcl-2-binding component 3 isoform 3 that is encoded in the genome of human." [PRO:JAN]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q99ML1-1 mBBC3/iso:1 enablesGO:0005515 protein binding with PR:P63168 8 kDa dynein light chain (mouse) PMID:10198631
PR:Q9BXH1-1 hBBC3/iso:1 acts_upstream_of_or_withinGO:0001836 release of cytochrome c from mitochondria PMID:11463392
GO:0006915 apoptotic process PMID:11463392
GO:0006915 apoptotic process PMID:11463392
enablesGO:0005515 protein binding with PR:P10415 BCL2 PMID:11463391
GO:0005515 protein binding with PR:Q07817-1 PMID:11463391
located_inGO:0005739 mitochondrion PMID:11463392
GO:0005739 mitochondrion PMID:11463392