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Protein Ontology report - proto-oncogene vav
PR:000003118 - http://purl.obolibrary.org/obo/PR_000003118
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000003118   
  PRO nameproto-oncogene vav 
  Synonyms
PRO-Short-label: EXACT:VAV1
Gene-based: RELATED:VAV
Other: EXACT:p95vav
  Definition"A protein that is a translation product of the human VAV1 gene or a 1:1 ortholog thereof. Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation." [PRO:CL, UniProtKB:P15498
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000003118

proto-oncogene vav

VAV1


"A protein that is a translation product of the human VAV1 gene or a 1:1 ortholog thereof. Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation." [PRO:CL, UniProtKB:P15498]


organism-gene



PR:P15498

proto-oncogene vav (human)

hVAV1


"A proto-oncogene vav that is encoded in the genome of human." [PRO:CL, UniProtKB:P15498]


organism-sequence



PR:P15498-1

proto-oncogene vav isoform 1 (human)

hVAV1/iso:1


"A proto-oncogene vav isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P15498-2

proto-oncogene vav isoform h2 (human)

hVAV1/iso:h2


"A proto-oncogene vav (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15498-2." [PRO:DNx, UniProtKB:P15498]


organism-modification



PR:000045684

proto-oncogene vav phosphorylated 1 (human)

hVAV1/Phos:1


"A proto-oncogene vav (human) that has been phosphorylated on the residue at the position equivalent to Tyr-267 of the amino acid sequence represented by UniProtKB:P15498-1. Example: UniProtKB:P15498-1, Tyr-267, MOD:00048." [iPTMnet:P15498, PMID:23325923]


organism-modification



PR:000049642

proto-oncogene vav phosphorylated 2 (human)

hVAV1/Phos:2


"A proto-oncogene vav (human) that has been post-translationally modified to include phosphotyrosine at positions 142, 160 and 174 of the amino acid sequence represented by UniProtKB:P15498. UniProtKB:P15498, Tyr-142/Tyr-160/Tyr-174, MOD:00048." [PRO:DNx, Reactome:R-HSA-389323]


organism-modification



PR:000049643

proto-oncogene vav phosphorylated 3 (human)

hVAV1/Phos:3


"A proto-oncogene vav (human) that has been phosphorylated on the residue at the position equivalent to Tyr-174 of the amino acid sequence represented by UniProtKB:P15498. UniProtKB:P15498, Tyr-174, MOD:00048." [PRO:DNx, Reactome:R-HSA-437946]


organism-modification



PR:000061375

proto-oncogene vav phosphotyrosine form (human)

hVAV1/PhosTyr+


"A proto-oncogene vav (human) that includes at least one phosphorylated tyrosine. UniProtKB:P15498, MOD:00048." [PRO:DNx, Reactome:R-HSA-9029087]


organism-modification



PR:000071059

proto-oncogene vav phosphorylated 4 (human)

hVAV1/Phos:4


"A proto-oncogene vav (human) that has been phosphorylated on the residue at the position equivalent to Thr-574 of the amino acid sequence represented by UniProtKB:P15498-1. Example: UniProtKB:P15498-1, Thr-574, MOD:00047." [IEDB_epitope:2146512, PRO:DNx]


organism-modification



PR:000071499

proto-oncogene vav methylated 1 (human)

hVAV1/Me:1


"A proto-oncogene vav (human) that has been methylated on the residue at the position equivalent to Cys-652 of the amino acid sequence represented by UniProtKB:P15498-1. Example: UniProtKB:P15498-1, Cys-652, MOD:00660." [IEDB_epitope:1008039, PRO:DNx]


organism-gene



PR:P27870

proto-oncogene vav (mouse)

mVAV1


"A proto-oncogene vav that is encoded in the genome of mouse." [OMA:P27870, PRO:DNx]


organism-sequence



PR:P27870-1

proto-oncogene vav isoform 1 (mouse)

mVAV1/iso:1


"A proto-oncogene vav isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P54100

proto-oncogene vav (rat)

rVAV1


"A proto-oncogene vav that is encoded in the genome of rat." [OMA:P54100, PRO:DNx]


sequence



PR:000038933

proto-oncogene vav isoform 1

VAV1/iso:1


"A proto-oncogene vav that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15498-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P15498-1

proto-oncogene vav isoform 1 (human)

hVAV1/iso:1


"A proto-oncogene vav isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P27870-1

proto-oncogene vav isoform 1 (mouse)

mVAV1/iso:1


"A proto-oncogene vav isoform 1 that is encoded in the genome of mouse." [PRO:DNx]