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Protein Ontology report - map kinase p38
PR:000003106 - http://purl.obolibrary.org/obo/PR_000003106
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003106   
  PRO namemap kinase p38 
  Synonyms
PRO-Short-label: EXACT:fam:MAPKp38
  Definition"A protein that is a serine/threonine-specific protein kinase that responds to extracellular stimuli (environmental stress, pro-inflammatory cytokines and lipopolysaccharide) and regulates cellular activities such as gene expression, mitosis, differentiation, and cell survival/apoptosis. The activated form phosphorylates target substrates on Ser or Thr residues followed by a proline. A distinguishing feature is the conserved sequence TxY." [PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 13                                        
         Sequence4                                                  Organism-Sequence 18                                        
         Modification3                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500943
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000003106 map kinase p38
fam:MAPKp38

gene


PR:000003107 mitogen-activated protein kinase 14
MAPK14

organism-gene


PR:P47811 mitogen-activated protein kinase 14 (mouse)
mMAPK14

organism-sequence


PR:P47811-1 mitogen-activated protein kinase 14 isoform 1 (mouse)
mMAPK14/iso:1
Yes
organism-sequence


PR:P47811-2 mitogen-activated protein kinase 14 isoform m2 (mouse)
mMAPK14/iso:m2

organism-sequence


PR:P47811-3 mitogen-activated protein kinase 14 isoform 3 (mouse)
mMAPK14/iso:3

organism-sequence


PR:P47811-4 mitogen-activated protein kinase 14 isoform m4 (mouse)
mMAPK14/iso:m4

organism-gene


PR:Q16539 mitogen-activated protein kinase 14 (human)
hMAPK14

organism-sequence


PR:Q16539-1 mitogen-activated protein kinase 14 isoform CSBP2 (human)
hMAPK14/iso:CSBP2

organism-sequence


PR:Q16539-2 mitogen-activated protein kinase 14 isoform CSBP1 (human)
hMAPK14/iso:CSBP1

organism-sequence


PR:Q16539-3 mitogen-activated protein kinase 14 isoform hMxi2 (human)
hMAPK14/iso:hMxi2

organism-sequence


PR:Q16539-4 mitogen-activated protein kinase 14 isoform Exip (human)
hMAPK14/iso:Exip

organism-sequence


PR:Q16539-5 mitogen-activated protein kinase 14 isoform h5 (human)
hMAPK14/iso:h5

organism-modification


PR:000036637 mitogen-activated protein kinase 14 phosphorylated 1 (human)
hMAPK14/Phos:1
Yes
organism-modification


PR:000048319 mitogen-activated protein kinase 14, initiator methionine removed form (human)
hMAPK14/InitMet-

organism-modification


PR:000048320 mitogen-activated protein kinase 14, initiator methionine removed phosphorylated 1 (human)
hMAPK14/InitMet-/Phos:1

organism-modification


PR:000067949 mitogen-activated protein kinase 14 deaminated 1 (human)
hMAPK14/Deam:1

sequence


PR:000040708 mitogen-activated protein kinase 14 isoform 1
MAPK14/iso:1

organism-sequence


PR:P47811-1 mitogen-activated protein kinase 14 isoform 1 (mouse)
mMAPK14/iso:1
Yes
organism-sequence


PR:Q16539-1 mitogen-activated protein kinase 14 isoform CSBP2 (human)
hMAPK14/iso:CSBP2

sequence


PR:000040709 mitogen-activated protein kinase 14 isoform 2
MAPK14/iso:2

organism-sequence


PR:P47811-3 mitogen-activated protein kinase 14 isoform 3 (mouse)
mMAPK14/iso:3

organism-sequence


PR:Q16539-2 mitogen-activated protein kinase 14 isoform CSBP1 (human)
hMAPK14/iso:CSBP1

modification


PR:000003108 mitogen-activated protein kinase 14 phosphorylated form
MAPK14/PhosRes+

modification


PR:000003109 mitogen-activated protein kinase 14 phosphorylated 1
MAPK14/Phos:1

organism-modification


PR:000036637 mitogen-activated protein kinase 14 phosphorylated 1 (human)
hMAPK14/Phos:1
Yes
organism-modification


PR:000048320 mitogen-activated protein kinase 14, initiator methionine removed phosphorylated 1 (human)
hMAPK14/InitMet-/Phos:1

modification


PR:000018784 mitogen-activated protein kinase 14, initiator methionine removed form
MAPK14/InitMet-

organism-modification


PR:000048319 mitogen-activated protein kinase 14, initiator methionine removed form (human)
hMAPK14/InitMet-

organism-modification


PR:000048320 mitogen-activated protein kinase 14, initiator methionine removed phosphorylated 1 (human)
hMAPK14/InitMet-/Phos:1

gene


PR:000010152 mitogen-activated protein kinase 11
MAPK11

organism-gene


PR:Q15759 mitogen-activated protein kinase 11 (human)
hMAPK11

organism-sequence


PR:Q15759-1 mitogen-activated protein kinase 11 isoform 1 (human)
hMAPK11/iso:1

organism-sequence


PR:Q15759-3 mitogen-activated protein kinase 11 isoform h2 (human)
hMAPK11/iso:h2

organism-modification


PR:000048316 mitogen-activated protein kinase 11 phosphorylated 1 (human)
hMAPK11/Phos:1

organism-gene


PR:Q17446 mitogen-activated protein kinase pmk-1 (worm)
MAPK11 (worm)

organism-gene


PR:Q9WUI1 mitogen-activated protein kinase 11 (mouse)
mMAPK11

organism-sequence


PR:Q9WUI1-1 mitogen-activated protein kinase 11 isoform 1 (mouse)
mMAPK11/iso:1

sequence


PR:000040668 mitogen-activated protein kinase 11 isoform 1
MAPK11/iso:1

organism-sequence


PR:Q15759-1 mitogen-activated protein kinase 11 isoform 1 (human)
hMAPK11/iso:1

organism-sequence


PR:Q9WUI1-1 mitogen-activated protein kinase 11 isoform 1 (mouse)
mMAPK11/iso:1

gene


PR:000010153 mitogen-activated protein kinase 12
MAPK12

organism-gene


PR:O08911 mitogen-activated protein kinase 12 (mouse)
mMAPK12

organism-sequence


PR:O08911-1 mitogen-activated protein kinase 12 isoform 1 (mouse)
mMAPK12/iso:1

organism-gene


PR:P53778 mitogen-activated protein kinase 12 (human)
hMAPK12

organism-sequence


PR:P53778-1 mitogen-activated protein kinase 12 isoform 1 (human)
hMAPK12/iso:1

organism-sequence


PR:P53778-2 mitogen-activated protein kinase 12 isoform h2 (human)
hMAPK12/iso:h2

organism-modification


PR:000048317 mitogen-activated protein kinase 12 phosphorylated 1 (human)
hMAPK12/Phos:1

organism-gene


PR:Q63538 mitogen-activated protein kinase 12 (rat)
rMAPK12

organism-sequence


PR:Q63538-1 mitogen-activated protein kinase 12 isoform 1 (rat)
rMAPK12/iso:1

sequence


PR:000039745 mitogen-activated protein kinase 12 isoform 1
MAPK12/iso:1

organism-sequence


PR:O08911-1 mitogen-activated protein kinase 12 isoform 1 (mouse)
mMAPK12/iso:1

organism-sequence


PR:P53778-1 mitogen-activated protein kinase 12 isoform 1 (human)
hMAPK12/iso:1

organism-sequence


PR:Q63538-1 mitogen-activated protein kinase 12 isoform 1 (rat)
rMAPK12/iso:1

gene


PR:000010154 mitogen-activated protein kinase 13
MAPK13

organism-gene


PR:O15264 mitogen-activated protein kinase 13 (human)
hMAPK13

organism-sequence


PR:O15264-1 mitogen-activated protein kinase 13 isoform 1 (human)
hMAPK13/iso:1

organism-sequence


PR:O15264-2 mitogen-activated protein kinase 13 isoform h2 (human)
hMAPK13/iso:h2

organism-modification


PR:000048318 mitogen-activated protein kinase 13 phosphorylated 1 (human)
hMAPK13/Phos:1

organism-gene


PR:Q9WTY9 mitogen-activated protein kinase 13 (rat)
rMAPK13

organism-gene


PR:Q9Z1B7 mitogen-activated protein kinase 13 (mouse)
mMAPK13

organism-gene


PR:Q9DGE1 mitogen-activated protein kinase 14B (zebrafish)
z-mapk14b

organism-gene


PR:Q9DGE2 mitogen-activated protein kinase 14A (zebrafish)
z-mapk14a

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036637 hMAPK14/Phos:1
Example: UniProtKB:Q16539-1, Thr-180, MOD:00047|Tyr-182, MOD:00048		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:15642743
enablesGO:0004707 MAP kinase activity PMID:15642743
GO:0005515 protein binding PMID:15642743
PR:P47811-1 mMAPK14/iso:1 acts_upstream_of_or_withinGO:0014835 myoblast differentiation involved in skeletal muscle regeneration MGI_ref:4838005; PMID:20610565