|
|
 |
|
| | |
| | | | | | | |
gene
|
|
PR:000003090 |
cyclin-dependent kinase inhibitor 1B
|
CDKN1B
|
"A protein that is a translation product of the human CDKN1B gene or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P46414 |
cyclin-dependent kinase inhibitor 1B (mouse)
|
mCDKN1B
|
"A cyclin-dependent kinase inhibitor 1B that is encoded in the genome of mouse." [OMA:P46414, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P46414-1 |
cyclin-dependent kinase inhibitor 1B isoform 1 (mouse)
|
mCDKN1B/iso:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046182 |
cyclin-dependent kinase inhibitor 1B phosphorylated 1 (mouse)
|
mCDKN1B/Phos:1
|
"A cyclin-dependent kinase inhibitor 1B (mouse) that has been phosphorylated at Ser-10. UniProtKB:P46414, Ser-10, MOD:00046." [iPTMnet:P46414, PMID:15010468]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P46527 |
cyclin-dependent kinase inhibitor 1B (human)
|
hCDKN1B
|
"A cyclin-dependent kinase inhibitor 1B that is encoded in the genome of human." [PRO:CNA, UniProtKB:P46527]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P46527-1 |
cyclin-dependent kinase inhibitor 1B isoform 1 (human)
|
hCDKN1B/iso:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000025750 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
|
hCDKN1B/iso:1/Phos:2
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000025752 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 (human)
|
hCDKN1B/iso:1/Phos:3
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 in human. UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036634 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human)
|
hCDKN1B/iso:1/Phos:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 in human. UniProtKB:P46527-1, Thr-157, MOD:00047." [PMID:12244301, PMID:15057270, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000045370 |
cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human)
|
hCDKN1B/iso:1/UnPhos:2
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 (human) that lacks phosphorylation at Tyr-88. UniProtKB:P46527-1, Tyr-88, PR:000026291." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000045790 |
cyclin-dependent kinase inhibitor 1B phosphorylated 1 (human)
|
hCDKN1B/Phos:1
|
"A cyclin-dependent kinase inhibitor 1B (human) that has been phosphorylated at Thr-198. UniProtKB:P46527, Thr-198, MOD:00047." [iPTMnet:P46527, PMID:15280662]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046682 |
cyclin-dependent kinase inhibitor 1B phosphorylated 4 (human)
|
hCDKN1B/Phos:4
|
"A cyclin-dependent kinase inhibitor 1B (human) that has been phosphorylated on the residue at the position equivalent to Thr-187 of the amino acid sequence represented by UniProtKB:P46527. UniProtKB:P46527, Thr-187, MOD:00047." [PRO:DNx, Reactome:R-HSA-187525]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000046683 |
cyclin-dependent kinase inhibitor 1B phosphorylated 2 (human)
|
hCDKN1B/Phos:2
|
"A cyclin-dependent kinase inhibitor 1B (human) that has been phosphorylated on the residue at the position equivalent to Tyr-88 of the amino acid sequence represented by UniProtKB:P46527. UniProtKB:P46527, Tyr-88, MOD:00048." [PRO:DNx, Reactome:R-HSA-8848438]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000060524 |
cyclin-dependent kinase inhibitor 1B phosphorylated 3 (human)
|
hCDKN1B/Phos:3
|
"A cyclin-dependent kinase inhibitor 1B (human) that has been phosphorylated on the residue at the position equivalent to Ser-10 of the amino acid sequence represented by UniProtKB:P46527. UniProtKB:P46527, Ser-10, MOD:00046." [PRO:DNx, Reactome:R-HSA-9632829, Reactome:R-HSA-9632832]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000062722 |
cyclin-dependent kinase inhibitor 1B phosphorylated 5 (human)
|
hCDKN1B/Phos:5
|
"A cyclin-dependent kinase inhibitor 1B (human) that has been phosphorylated on the residue at the position equivalent to Thr-157 of the amino acid sequence represented by UniProtKB:P46527. UniProtKB:P46527, Thr-157, MOD:00047." [PRO:DNx, Reactome:R-HSA-198629]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000073909 |
cyclin-dependent kinase inhibitor 1B methylated 1 (human)
|
hCDKN1B/Me:1
|
"A cyclin-dependent kinase inhibitor 1B (human) that has been methylated on the residue at the position equivalent to Cys-29 of the amino acid sequence represented by UniProtKB:P46527. UniProtKB:P46527, Cys-29, MOD:00660." [IEDB_epitope:1018732, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
sequence
|
|
PR:000003091 |
cyclin-dependent kinase inhibitor 1B isoform 1
|
CDKN1B/iso:1
|
"A cyclin-dependent kinase inhibitor 1B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46527-1 or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P46414-1 |
cyclin-dependent kinase inhibitor 1B isoform 1 (mouse)
|
mCDKN1B/iso:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P46527-1 |
cyclin-dependent kinase inhibitor 1B isoform 1 (human)
|
hCDKN1B/iso:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000025750 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
|
hCDKN1B/iso:1/Phos:2
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000025752 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 (human)
|
hCDKN1B/iso:1/Phos:3
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 in human. UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036634 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human)
|
hCDKN1B/iso:1/Phos:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 in human. UniProtKB:P46527-1, Thr-157, MOD:00047." [PMID:12244301, PMID:15057270, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000045370 |
cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human)
|
hCDKN1B/iso:1/UnPhos:2
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 (human) that lacks phosphorylation at Tyr-88. UniProtKB:P46527-1, Tyr-88, PR:000026291." [PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000003092 |
cyclin-dependent kinase inhibitor 1B isoform 1 unmodified form
|
CDKN1B/iso:1/UnMod
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000003093 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form
|
CDKN1B/iso:1/PhosRes+
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000003094 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1
|
CDKN1B/iso:1/Phos:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs within the nuclear localization sequence (NLS)." [PMID:15057270, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036634 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human)
|
hCDKN1B/iso:1/Phos:1
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 in human. UniProtKB:P46527-1, Thr-157, MOD:00047." [PMID:12244301, PMID:15057270, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000025749 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2
|
CDKN1B/iso:1/Phos:2
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000025750 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
|
hCDKN1B/iso:1/Phos:2
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000025751 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3
|
CDKN1B/iso:1/Phos:3
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain, and phosphorylated by CDK2 on a Thr residue in the C-terminal region. Phosphorylation by CDK2 promotes degradation by the SCF-Skp2 ubiquitin-proteasome pathway. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000025752 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 (human)
|
hCDKN1B/iso:1/Phos:3
|
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 in human. UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA]
|
|
|
|
|
