|
|
 |
|
| | |
| | | | | | | |
gene
|
|
PR:000003064 |
tyrosine-protein kinase ZAP-70
|
ZAP70
|
"A SYK/ZAP-70 family tyrosine-protein kinase that is a translation product of the human ZAP70 gene or a 1:1 ortholog thereof." [PRO:CL]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:A0A0R4J8U1 |
tyrosine-protein kinase (rat)
|
rZAP70
|
"A tyrosine-protein kinase ZAP-70 that is encoded in the genome of rat." [PRO:CL]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P43403 |
tyrosine-protein kinase ZAP-70 (human)
|
hZAP70
|
"A tyrosine-protein kinase ZAP-70 that is encoded in the genome of human." [PRO:CL, UniProtKB:P43403]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43403-1 |
tyrosine-protein kinase ZAP-70 isoform 1 (human)
|
hZAP70/iso:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036629 |
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human)
|
hZAP70/iso:1/Phos:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 in human." [PMID:9269777, PRO:CL]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43403-2 |
tyrosine-protein kinase ZAP-70 isoform 2 (human)
|
hZAP70/iso:2
|
"A tyrosine-protein kinase ZAP-70 isoform 2 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43403-3 |
tyrosine-protein kinase ZAP-70 isoform h3 (human)
|
hZAP70/iso:h3
|
"A tyrosine-protein kinase ZAP-70 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43403-3." [PRO:DNx, UniProtKB:P43403]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000045788 |
tyrosine-protein kinase ZAP-70 phosphorylated 1 (human)
|
hZAP70/Phos:1
|
"A tyrosine-protein kinase ZAP-70 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-319 of the amino acid sequence represented by UniProtKB:P43403-1. Example: UniProtKB:P43403-1, Tyr-319, MOD:00048." [iPTMnet:P43403, PMID:10202147, PMID:10318843, PMID:15292262]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049722 |
tyrosine-protein kinase ZAP-70 phosphorylated 2 (human)
|
hZAP70/Phos:2
|
"A tyrosine-protein kinase ZAP-70 (human) that has been phosphorylated on residues at positions equivalent to Thr-315 and Thr-493 of the amino acid sequence represented by UniProtKB:P43403-1. Example: UniProtKB:P43403-1, Tyr-315/Tyr-493, MOD:00048." [PRO:DNx, Reactome:R-HSA-202252]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000049723 |
tyrosine-protein kinase ZAP-70 phosphorylated 3 (human)
|
hZAP70/Phos:3
|
"A tyrosine-protein kinase ZAP-70 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-493 of the amino acid sequence represented by UniProtKB:P43403-1. Example: UniProtKB:P43403-1, Tyr-493, MOD:00048." [PRO:DNx, Reactome:R-HSA-202368]
|
|
|
|
|
|
|
| | | | |
| | | | | |
organism-gene
|
|
PR:P43404 |
tyrosine-protein kinase ZAP-70 (mouse)
|
mZAP70
|
"A tyrosine-protein kinase ZAP-70 that is encoded in the genome of mouse." [OMA:P43404, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43404-1 |
tyrosine-protein kinase ZAP-70 isoform 1 (mouse)
|
mZAP70/iso:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43404-2 |
tyrosine-protein kinase ZAP-70 isoform 2 (mouse)
|
mZAP70/iso:2
|
"A tyrosine-protein kinase ZAP-70 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43404-3 |
tyrosine-protein kinase ZAP-70 isoform m3 (mouse)
|
mZAP70/iso:m3
|
"A tyrosine-protein kinase ZAP-70 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43404-3." [PRO:DNx, UniProtKB:P43404]
|
|
|
|
|
|
|
| | | | |
| | | | | |
sequence
|
|
PR:000003066 |
tyrosine-protein kinase ZAP-70 isoform 1
|
ZAP70/iso:1
|
"A tyrosine-protein kinase ZAP-70 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43403-1 or a 1:1 ortholog thereof." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43403-1 |
tyrosine-protein kinase ZAP-70 isoform 1 (human)
|
hZAP70/iso:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036629 |
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human)
|
hZAP70/iso:1/Phos:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 in human." [PMID:9269777, PRO:CL]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43404-1 |
tyrosine-protein kinase ZAP-70 isoform 1 (mouse)
|
mZAP70/iso:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000003067 |
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated form
|
ZAP70/iso:1/PhosRes+
|
"A tyrosine-protein kinase ZAP-70 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000003068 |
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1
|
ZAP70/iso:1/Phos:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated form in which the phosphorylation occurs on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck, following TCR engagement. Tyrosine phosphorylation correlates with increased Zap-70 kinase activity and downstream signaling events. It has been shown that Tyr-319 in the human sequence is required for the positive regulation of ZAP-70 function." [PMID:10037717, PRO:CL]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036629 |
tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 (human)
|
hZAP70/iso:1/Phos:1
|
"A tyrosine-protein kinase ZAP-70 isoform 1 phosphorylated 1 in human." [PMID:9269777, PRO:CL]
|
Yes |
|
|
|
|
|
| | | | |
| | | | | |
sequence
|
|
PR:000039469 |
tyrosine-protein kinase ZAP-70 isoform 2
|
ZAP70/iso:2
|
"A tyrosine-protein kinase ZAP-70 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43403-2 or a 1:1 ortholog thereof." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43403-2 |
tyrosine-protein kinase ZAP-70 isoform 2 (human)
|
hZAP70/iso:2
|
"A tyrosine-protein kinase ZAP-70 isoform 2 that is encoded in the genome of human." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-sequence
|
|
PR:P43404-2 |
tyrosine-protein kinase ZAP-70 isoform 2 (mouse)
|
mZAP70/iso:2
|
"A tyrosine-protein kinase ZAP-70 isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
|
|
|
|
|
