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Protein Ontology report - protein kinase C beta type
PR:000003059 - http://purl.obolibrary.org/obo/PR_000003059
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003059   
  PRO nameprotein kinase C beta type 
  Synonyms
PRO-Short-label: EXACT:PRKCB
Gene-based: RELATED:PKCB | PRKCB1
Other: EXACT:PKC-B | PKC-beta
  Definition"A conventional protein kinase C that is a translation product of the human PRKCB gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000003057 conventional protein kinase C
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 6                                        
         Modification2                                                  Organism-Modification 16                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1483
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003059
protein kinase C beta type
PRKCB
"A conventional protein kinase C that is a translation product of the human PRKCB gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:P05771
protein kinase C beta type (human)
hPRKCB
"A protein kinase C beta type that is encoded in the genome of human." [PRO:CNA, UniProtKB:P05771]

organism-sequence


PR:P05771-1
protein kinase C beta type isoform Beta-I (human)
hPRKCB/iso:Beta-I
"A protein kinase C beta type isoform 1 that is encoded in the genome of human." [PRO:DNx]
Yes
organism-sequence


PR:P05771-2
protein kinase C beta type isoform Beta-II (human)
hPRKCB/iso:Beta-II
"A protein kinase C beta type isoform 2 that is encoded in the genome of human." [PRO:DNx]
Yes
organism-modification


PR:000049853
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049854
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and lacks a phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000049855
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the activation loop, and phosphothreonine at position 641 and phosphoserine at position 660 of the Pkinase_C domain (Pfam:PF00433). UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049856
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500,a phosphothreonine at position 641 and a phosphoserine at position 660. UniProtKB:P05771-2, 2-673, Thr-500/Thr-641/Ser-660, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000048913
protein kinase C beta type, initiator methionine removed form (human)
hPRKCB/InitMet-
"A protein kinase C beta type (human) that has had the initiator methionine removed. UniProtKB:P05771, 2-671." [PRO:DNx, Reactome:R-HSA-156467, Reactome:R-HSA-58198]

organism-modification


PR:000048914
protein kinase C beta type, initiator methionine removed phosphorylated 1 (human)
hPRKCB/InitMet-/Phos:1
"A protein kinase C beta type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the amino acid sequence represented by UniProtKB:P05771. UniProtKB:P05771, 2-671, Thr-500, MOD:00047." [PRO:DNx, Reactome:R-HSA-5218728]

organism-modification


PR:000048915
protein kinase C beta type, initiator methionine removed phosphorylated 2 (human)
hPRKCB/InitMet-/Phos:2
"A protein kinase C beta type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 500 and 642, and phosphoserine at position 661 of the amino acid sequence represented by UniProtKB:P05771. UniProtKB:P05771, 2-671, Thr-500/Thr-642, MOD:00047|Ser-661, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218706, Reactome:R-HSA-5223294]

organism-modification


PR:000049853
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049854
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and lacks a phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000049855
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the activation loop, and phosphothreonine at position 641 and phosphoserine at position 660 of the Pkinase_C domain (Pfam:PF00433). UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049856
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500,a phosphothreonine at position 641 and a phosphoserine at position 660. UniProtKB:P05771-2, 2-673, Thr-500/Thr-641/Ser-660, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000049887
protein kinase C beta type phosphorylated 1 (human)
hPRKCB/Phos:1
"A protein kinase C beta type phosphorylated 1 in human. UniProtKB:P05771, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]

organism-gene


PR:P68403
protein kinase C beta type (rat)
rPRKCB
"A protein kinase C beta type that is encoded in the genome of rat." [OMA:P68403, PRO:DNx]

organism-sequence


PR:P68403-1
protein kinase C beta type isoform Beta-I (rat)
rPRKCB/iso:Beta-I
"A protein kinase C beta type (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P68403-1." [PRO:DNx, UniProtKB:P68403]

organism-sequence


PR:P68403-2
protein kinase C beta type isoform Beta-II (rat)
rPRKCB/iso:Beta-II
"A protein kinase C beta type (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P68403-2." [PRO:DNx, UniProtKB:P68403]

organism-gene


PR:P68404
protein kinase C beta type (mouse)
mPRKCB
"A protein kinase C beta type that is encoded in the genome of mouse." [OMA:MOUSE21322, PRO:DNx]

organism-sequence


PR:P68404-1
protein kinase C beta type isoform Beta-I (mouse)
mPRKCB/iso:Beta-I
"A protein kinase C beta type isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000049880
protein kinase C beta type isoform Beta-I phosphorylated 1 (mouse)
mPRKCB/iso:Beta-I/Phos:1
"A protein kinase C beta type isoform Beta-I (mouse) that has been phosphorylated at position Thr-642. UniProtKB:P68404-1, Thr-642, MOD:00047." [PMID:21183079, PRO:DAN, PRO:HJD]

organism-sequence


PR:P68404-2
protein kinase C beta type isoform Beta-II (mouse)
mPRKCB/iso:Beta-II
"A protein kinase C beta type isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000049876
protein kinase C beta type isoform Beta-II phosphorylated 1 (mouse)
mPRKCB/iso:Beta-II/Phos:1
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at position Thr-641. UniProtKB:P68404-2, Thr-641, MOD:00047." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049877
protein kinase C beta type isoform Beta-II phosphorylated 2 (mouse)
mPRKCB/iso:Beta-II/Phos:2
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at Ser-654 and Ser-660. UniProtKB:P68404-2, Ser-654/Ser-660, MOD:00046." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049878
protein kinase C beta type isoform Beta-II phosphorylated 3 (mouse)
mPRKCB/iso:Beta-II/Phos:3
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at Ser-660 and Ser-664. UniProtKB:P68404-2, Ser-660/Ser-664, MOD:00046." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049879
protein kinase C beta type isoform Beta-II phosphorylated 4 (mouse)
mPRKCB/iso:Beta-II/Phos:4
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at Ser-660 and Ser-673. UniProtKB:P68404-2, Ser-660/Ser-673, MOD:00046." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049881
protein kinase C beta type phosphorylated 2 (mouse)
mPRKCB/Phos:2
"A protein kinase C beta type (mouse) that has been phosphorylated on the residue at the position equivalent to Ser-206 of the amino acid sequence represented by UniProtKB:P68404-1. Example: UniProtKB:P68404-1, Ser-206, MOD:00046." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049882
protein kinase C beta type phosphorylated 1 (mouse)
mPRKCB/Phos:1
"A protein kinase C beta type phosphorylated 1 in mouse. Example: UniProtKB:P68404-1, Thr-500, MOD:00047." [PMID:21183079, PRO:DAN, PRO:HJD]

organism-modification


PR:000049883
protein kinase C beta type phosphorylated 3 (mouse)
mPRKCB/Phos:3
"A protein kinase C beta type (mouse) that has been phosphorylated on the residue at the position equivalent to Thr-504 of the amino acid sequence represented by UniProtKB:P68404-1. Example: UniProtKB:P68404-1, Thr-504, MOD:00047." [PMID:21183079, PRO:HJD]

organism-gene


PR:Q7SY24
protein kinase C beta type (zebrafish)
z-PRKCB
"A protein kinase C beta type that is encoded in the genome of zebrafish." [PRO:CNA]

sequence


PR:000038682
protein kinase C beta type isoform 1
PRKCB/iso:1
"A protein kinase C beta type that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05771-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P05771-1
protein kinase C beta type isoform Beta-I (human)
hPRKCB/iso:Beta-I
"A protein kinase C beta type isoform 1 that is encoded in the genome of human." [PRO:DNx]
Yes
organism-sequence


PR:P68404-1
protein kinase C beta type isoform Beta-I (mouse)
mPRKCB/iso:Beta-I
"A protein kinase C beta type isoform 1 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000049880
protein kinase C beta type isoform Beta-I phosphorylated 1 (mouse)
mPRKCB/iso:Beta-I/Phos:1
"A protein kinase C beta type isoform Beta-I (mouse) that has been phosphorylated at position Thr-642. UniProtKB:P68404-1, Thr-642, MOD:00047." [PMID:21183079, PRO:DAN, PRO:HJD]

sequence


PR:000038683
protein kinase C beta type isoform 2
PRKCB/iso:2
"A protein kinase C beta type that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05771-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P05771-2
protein kinase C beta type isoform Beta-II (human)
hPRKCB/iso:Beta-II
"A protein kinase C beta type isoform 2 that is encoded in the genome of human." [PRO:DNx]
Yes
organism-modification


PR:000049853
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049854
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and lacks a phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000049855
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the activation loop, and phosphothreonine at position 641 and phosphoserine at position 660 of the Pkinase_C domain (Pfam:PF00433). UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049856
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500,a phosphothreonine at position 641 and a phosphoserine at position 660. UniProtKB:P05771-2, 2-673, Thr-500/Thr-641/Ser-660, PR:000026291." [PMID:8749392, PRO:KER]

organism-sequence


PR:P68404-2
protein kinase C beta type isoform Beta-II (mouse)
mPRKCB/iso:Beta-II
"A protein kinase C beta type isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-modification


PR:000049876
protein kinase C beta type isoform Beta-II phosphorylated 1 (mouse)
mPRKCB/iso:Beta-II/Phos:1
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at position Thr-641. UniProtKB:P68404-2, Thr-641, MOD:00047." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049877
protein kinase C beta type isoform Beta-II phosphorylated 2 (mouse)
mPRKCB/iso:Beta-II/Phos:2
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at Ser-654 and Ser-660. UniProtKB:P68404-2, Ser-654/Ser-660, MOD:00046." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049878
protein kinase C beta type isoform Beta-II phosphorylated 3 (mouse)
mPRKCB/iso:Beta-II/Phos:3
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at Ser-660 and Ser-664. UniProtKB:P68404-2, Ser-660/Ser-664, MOD:00046." [PMID:21183079, PRO:HJD]

organism-modification


PR:000049879
protein kinase C beta type isoform Beta-II phosphorylated 4 (mouse)
mPRKCB/iso:Beta-II/Phos:4
"A protein kinase C beta type isoform Beta-II (mouse) that has been phosphorylated at Ser-660 and Ser-673. UniProtKB:P68404-2, Ser-660/Ser-673, MOD:00046." [PMID:21183079, PRO:HJD]

modification


PR:000018783
protein kinase C beta type, initiator methionine removed form
PRKCB/InitMet-
"A protein kinase C beta type that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000048913
protein kinase C beta type, initiator methionine removed form (human)
hPRKCB/InitMet-
"A protein kinase C beta type (human) that has had the initiator methionine removed. UniProtKB:P05771, 2-671." [PRO:DNx, Reactome:R-HSA-156467, Reactome:R-HSA-58198]

organism-modification


PR:000048914
protein kinase C beta type, initiator methionine removed phosphorylated 1 (human)
hPRKCB/InitMet-/Phos:1
"A protein kinase C beta type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the amino acid sequence represented by UniProtKB:P05771. UniProtKB:P05771, 2-671, Thr-500, MOD:00047." [PRO:DNx, Reactome:R-HSA-5218728]

organism-modification


PR:000048915
protein kinase C beta type, initiator methionine removed phosphorylated 2 (human)
hPRKCB/InitMet-/Phos:2
"A protein kinase C beta type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 500 and 642, and phosphoserine at position 661 of the amino acid sequence represented by UniProtKB:P05771. UniProtKB:P05771, 2-671, Thr-500/Thr-642, MOD:00047|Ser-661, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218706, Reactome:R-HSA-5223294]

organism-modification


PR:000049853
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049854
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and lacks a phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000049855
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the activation loop, and phosphothreonine at position 641 and phosphoserine at position 660 of the Pkinase_C domain (Pfam:PF00433). UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049856
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500,a phosphothreonine at position 641 and a phosphoserine at position 660. UniProtKB:P05771-2, 2-673, Thr-500/Thr-641/Ser-660, PR:000026291." [PMID:8749392, PRO:KER]

modification


PR:000049888
protein kinase C beta type phosphorylated 1
PRKCB/Phos:1
"A protein kinase C beta type that has been phosphorylated on the residue at the position equivalent to Thr-500 of the amino acid sequence represented by UniProtKB:P05771-2. Example: UniProtKB:P05771-2, Thr-500, MOD:00047." [PMID:21183079, PMID:8749392, PRO:HJD, PRO:KER]

organism-modification


PR:000049882
protein kinase C beta type phosphorylated 1 (mouse)
mPRKCB/Phos:1
"A protein kinase C beta type phosphorylated 1 in mouse. Example: UniProtKB:P68404-1, Thr-500, MOD:00047." [PMID:21183079, PRO:DAN, PRO:HJD]

organism-modification


PR:000049887
protein kinase C beta type phosphorylated 1 (human)
hPRKCB/Phos:1
"A protein kinase C beta type phosphorylated 1 in human. UniProtKB:P05771, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000049853 hPRKCB/iso:Beta-II/InitMet-/Phos:1
UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047		 enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000049854 hPRKCB/iso:Beta-II/InitMet-/UnPhos:1 PMID:8749392
located_inGO:0005737 cytoplasm PMID:9756933
GO:0005886 plasma membrane PMID:9756933
PR:000049855 hPRKCB/iso:Beta-II/InitMet-/Phos:2
UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046		 acts_upstream_of_or_withinincreased GO:0006468 protein phosphorylation relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:8749392
enablesincreased GO:0001786 phosphatidylserine binding relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9218480
increased GO:0005509 calcium ion binding relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9218480
located_inincreased GO:0005737 cytoplasm relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9756933
PR:P05771-1 hPRKCB/iso:Beta-I acts_upstream_of_or_withinNOT GO:0001666 response to hypoxia MGI_ref:3847400; PMID:18323529
located_inGO:0016020 membrane MGI_ref:3847400; PMID:18323529
PR:P05771-2 hPRKCB/iso:Beta-II acts_upstream_of_or_withinGO:0001666 response to hypoxia MGI_ref:3847400; PMID:18323529
located_inGO:0016020 membrane MGI_ref:3847400; PMID:18323529