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Protein Ontology report - focal adhesion kinase
PR:000003030 - http://purl.obolibrary.org/obo/PR_000003030
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003030   
  PRO namefocal adhesion kinase 
  Synonyms
PRO-Short-label: EXACT:fam:FAK
  Definition"A protein that is a translation product of the human PTK2 or PTK2B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:CNA, PRO:DAN] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 7                                        
         Sequence4                                                  Organism-Sequence 22                                        
         Modification6                                                  Organism-Modification 34                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038851
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000003030

focal adhesion kinase

fam:FAK


"A protein that is a translation product of the human PTK2 or PTK2B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:CNA, PRO:DAN]


gene



PR:000003031

focal adhesion kinase 1

PTK2


"A focal adhesion kinase that is a translation product of the human PTK2 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:O35346

focal adhesion kinase 1 (rat)

rPTK2


"A focal adhesion kinase 1 that is encoded in the genome of rat." [OMA:O35346, PRO:DNx]


organism-sequence



PR:O35346-1

focal adhesion kinase 1 isoform 1 (rat)

rPTK2/iso:1


"A focal adhesion kinase 1 isoform 4 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000049946

focal adhesion kinase 1 isoform 1 phosphorylated 1 (rat)

rPTK2/iso:1/Phos:1


"A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated on the residue at the position equivalent to Tyr-397. UniProtKB:O35346-1, Tyr-397, MOD:00048." [PMID:27994061, PRO:LN]


organism-modification



PR:000049947

focal adhesion kinase 1 isoform 1 unphosphorylated 1 (rat)

rPTK2/iso:1/UnPhos:1


"A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at the position equivalent to Tyr-397. UniProtKB:O35346-1, Tyr-397, PR:000026291." [PMID:27994061, PRO:LN]


organism-modification



PR:000049948

focal adhesion kinase 1 isoform 1 phosphorylated 2 (rat)

rPTK2/iso:1/Phos:2


"A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated at positions equivalent to Tyr-576 and Tyr-577. UniProtKB:O35346-1, Tyr-576/Tyr-577, MOD:00048." [PMID:27994061, PRO:LN]


organism-modification



PR:000049949

focal adhesion kinase 1 isoform 1 unphosphorylated 2 (rat)

rPTK2/iso:1/UnPhos:2


"A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at positions equivalent to Tyr-576 and Tyr-577. UniProtKB:O35346-1, Tyr-576/Tyr-577, PR:000026291." [PMID:27994061, PRO:LN]


organism-modification



PR:000049950

focal adhesion kinase 1 isoform 1 phosphorylated 3 (rat)

rPTK2/iso:1/Phos:3


"A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated on the residue at the position equivalent to Tyr-928. UniProtKB:O35346-1, Tyr-928, MOD:00048." [PMID:27994061, PRO:LN]


organism-modification



PR:000049951

focal adhesion kinase 1 isoform 1 unphosphorylated 3 (rat)

rPTK2/iso:1/UnPhos:3


"A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at the position equivalent to Tyr-928. UniProtKB:O35346-1, Tyr-928, PR:000026291." [PMID:27994061, PRO:LN]


organism-sequence



PR:O35346-2

focal adhesion kinase 1 isoform r2 (rat)

rPTK2/iso:r2


"A focal adhesion kinase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35346-2." [PRO:DNx, UniProtKB:O35346]


organism-gene



PR:P34152

focal adhesion kinase 1 (mouse)

mPTK2


"A focal adhesion kinase 1 that is encoded in the genome of mouse." [OMA:P34152, PRO:DNx]


organism-sequence



PR:P34152-2

focal adhesion kinase 1 isoform m2 (mouse)

mPTK2/iso:m2


"A focal adhesion kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-2." [PRO:DNx, UniProtKB:P34152]


organism-sequence



PR:P34152-3

focal adhesion kinase 1 isoform 1 (mouse)

mPTK2/iso:1


"A focal adhesion kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P34152]


organism-sequence



PR:P34152-4

focal adhesion kinase 1 isoform 4 (mouse)

mPTK2/iso:4


"A focal adhesion kinase 1 isoform 4 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P34152-5

focal adhesion kinase 1 isoform m5 (mouse)

mPTK2/iso:m5


"A focal adhesion kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-5." [PRO:DNx, UniProtKB:P34152]


organism-sequence



PR:P34152-6

focal adhesion kinase 1 isoform m6 (mouse)

mPTK2/iso:m6


"A focal adhesion kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-6." [PRO:DNx, UniProtKB:P34152]


organism-sequence



PR:P34152-7

focal adhesion kinase 1 isoform m7 (mouse)

mPTK2/iso:m7


"A focal adhesion kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-7." [PRO:DNx, UniProtKB:P34152]


organism-sequence



PR:P34152-8

focal adhesion kinase 1 isoform m8 (mouse)

mPTK2/iso:m8


"A focal adhesion kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-8." [PRO:DNx, UniProtKB:P34152]


organism-sequence



PR:P34152-9

focal adhesion kinase 1 isoform m9 (mouse)

mPTK2/iso:m9


"A focal adhesion kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-9." [PRO:DNx, UniProtKB:P34152]


organism-modification



PR:000049943

focal adhesion kinase 1, initiator methionine removed form (mouse)

mPTK2/InitMet-


"A focal adhesion kinase 1 (mouse) that has had the initiator methionine removed. UniProtKB:P34152, 2-1052." [PRO:CNA, UniProtKB:P34152]


organism-modification



PR:000049944

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (mouse)

mPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in mouse. UniProtKB:P34152, 2-1052, Tyr-397, MOD:00048." [PMID:27994061, PRO:DAN, PRO:LN]


organism-modification



PR:000049945

focal adhesion kinase 1, initiator methionine removed unphosphorylated 1 (mouse)

mPTK2/InitMet-/UnPhos:1


"A focal adhesion kinase 1, initiator methionine removed form (mouse) that lacks phosphorylation on the residue at the position equivalent to Tyr-397 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397, PR:000026291." [PMID:27994061, PRO:LN]


organism-gene



PR:Q00944

focal adhesion kinase 1 (chicken)

chick-PTK2


"A focal adhesion kinase 1 that is encoded in the genome of chicken." [PRO:CNA]


organism-gene



PR:Q05397

focal adhesion kinase 1 (human)

hPTK2


"A focal adhesion kinase 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q05397]


organism-sequence



PR:Q05397-1

focal adhesion kinase 1 isoform 1 (human)

hPTK2/iso:1


"A focal adhesion kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]


organism-sequence



PR:Q05397-2

focal adhesion kinase 1 isoform h2 (human)

hPTK2/iso:h2


"A focal adhesion kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-2." [PRO:DNx, UniProtKB:Q05397]


organism-sequence



PR:Q05397-3

focal adhesion kinase 1 isoform h3 (human)

hPTK2/iso:h3


"A focal adhesion kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-3." [PRO:DNx, UniProtKB:Q05397]


organism-sequence



PR:Q05397-4

focal adhesion kinase 1 isoform h4 (human)

hPTK2/iso:h4


"A focal adhesion kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-4." [PRO:DNx, UniProtKB:Q05397]


organism-sequence



PR:Q05397-5

focal adhesion kinase 1 isoform h5 (human)

hPTK2/iso:h5


"A focal adhesion kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-5." [PRO:DNx, UniProtKB:Q05397]


organism-sequence



PR:Q05397-6

focal adhesion kinase 1 isoform h6 (human)

hPTK2/iso:h6


"A focal adhesion kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-6." [PRO:DNx, UniProtKB:Q05397]


organism-sequence



PR:Q05397-7

focal adhesion kinase 1 isoform h7 (human)

hPTK2/iso:h7


"A focal adhesion kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-7." [PRO:DNx, UniProtKB:Q05397]


organism-modification



PR:000048949

focal adhesion kinase 1, initiator methionine removed form (human)

hPTK2/InitMet-


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q05397, 2-1052." [PRO:DNx, Reactome:R-HSA-201621]


organism-modification



PR:000062510

focal adhesion kinase 1, initiator methionine removed phosphotyrosine form (human)

hPTK2/InitMet-/PhosTyr+


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that includes at least one phosphorylated tyrosine. Example: UniProtKB:Q05397-1, 2-1052, MOD:00048." [PRO:DNx, Reactome:R-HSA-9632393]


organism-modification



PR:000026218

focal adhesion kinase 1, initiator methionine removed phosphorylated 2 (human)

hPTK2/InitMet-/Phos:2


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 2 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-354128]


organism-modification



PR:000026219

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (human)

hPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397, MOD:00048." [PRO:CNx, Reactome:R-HSA-354068]


organism-modification



PR:000048950

focal adhesion kinase 1, initiator methionine removed phosphorylated 3 (human)

hPTK2/InitMet-/Phos:3


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 407, 576, 577, 861 and 925, and phosphoserine at position 732 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048|Ser-732, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218694]


organism-modification



PR:000048951

focal adhesion kinase 1, initiator methionine removed phosphorylated 4 (human)

hPTK2/InitMet-/Phos:4


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 576, 577, 861 and 925 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218711]


organism-modification



PR:000048952

focal adhesion kinase 1, initiator methionine removed phosphorylated 5 (human)

hPTK2/InitMet-/Phos:5


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 576, 577, 861 and 925, and phosphoserine at position 732 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048|Ser-732, MOD:00046." [PRO:DNx, Reactome:R-HSA-5229006]


organism-modification



PR:000062394

focal adhesion kinase 1, initiator methionine removed phosphorylated 6 (human)

hPTK2/InitMet-/Phos:6


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-194 and Tyr-397 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-194/Tyr-397, MOD:00048." [PRO:DNx, Reactome:R-HSA-8874600]


organism-modification



PR:000063617

focal adhesion kinase 1, initiator methionine removed phosphorylated 7 (human)

hPTK2/InitMet-/Phos:7


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-194, Tyr-397, Tyr-576, and Tyr-577 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-194/Tyr-397/Tyr-576/Tyr-577, MOD:00048." [PRO:DNx, Reactome:R-HSA-8874613]


organism-modification



PR:000062510

focal adhesion kinase 1, initiator methionine removed phosphotyrosine form (human)

hPTK2/InitMet-/PhosTyr+


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that includes at least one phosphorylated tyrosine. Example: UniProtKB:Q05397-1, 2-1052, MOD:00048." [PRO:DNx, Reactome:R-HSA-9632393]


organism-modification



PR:000026218

focal adhesion kinase 1, initiator methionine removed phosphorylated 2 (human)

hPTK2/InitMet-/Phos:2


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 2 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-354128]


organism-modification



PR:000026219

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (human)

hPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397, MOD:00048." [PRO:CNx, Reactome:R-HSA-354068]


organism-modification



PR:000048950

focal adhesion kinase 1, initiator methionine removed phosphorylated 3 (human)

hPTK2/InitMet-/Phos:3


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 407, 576, 577, 861 and 925, and phosphoserine at position 732 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048|Ser-732, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218694]


organism-modification



PR:000048951

focal adhesion kinase 1, initiator methionine removed phosphorylated 4 (human)

hPTK2/InitMet-/Phos:4


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 576, 577, 861 and 925 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218711]


organism-modification



PR:000048952

focal adhesion kinase 1, initiator methionine removed phosphorylated 5 (human)

hPTK2/InitMet-/Phos:5


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 576, 577, 861 and 925, and phosphoserine at position 732 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048|Ser-732, MOD:00046." [PRO:DNx, Reactome:R-HSA-5229006]


organism-modification



PR:000062394

focal adhesion kinase 1, initiator methionine removed phosphorylated 6 (human)

hPTK2/InitMet-/Phos:6


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-194 and Tyr-397 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-194/Tyr-397, MOD:00048." [PRO:DNx, Reactome:R-HSA-8874600]


organism-modification



PR:000063617

focal adhesion kinase 1, initiator methionine removed phosphorylated 7 (human)

hPTK2/InitMet-/Phos:7


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-194, Tyr-397, Tyr-576, and Tyr-577 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-194/Tyr-397/Tyr-576/Tyr-577, MOD:00048." [PRO:DNx, Reactome:R-HSA-8874613]


organism-modification



PR:000067330

focal adhesion kinase 1 cysteinylated 1 (human)

hPTK2/Cyst:1


"A focal adhesion kinase 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-647 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, Cys-647, MOD:00765." [IEDB_epitope:1578274, PRO:DNx]


organism-modification



PR:000073284

focal adhesion kinase 1 phosphorylated 1 (human)

hPTK2/Phos:1


"A focal adhesion kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-963 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, Thr-963, MOD:00047." [IEDB_epitope:843725, PRO:DNx]


sequence



PR:000026197

focal adhesion kinase 1 isoform 1

PTK2/iso:1


"A focal adhesion kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05397-1 or a 1:1 ortholog thereof." [PRO:CNx]


organism-sequence



PR:P34152-3

focal adhesion kinase 1 isoform 1 (mouse)

mPTK2/iso:1


"A focal adhesion kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA, UniProtKB:P34152]


organism-sequence



PR:Q05397-1

focal adhesion kinase 1 isoform 1 (human)

hPTK2/iso:1


"A focal adhesion kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]


modification



PR:000026628

focal adhesion kinase 1 isoform 1, initiator methionine removed form

PTK2/iso:1/InitMet-


"A focal adhesion kinase 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]


sequence



PR:000039313

focal adhesion kinase 1 isoform 4

PTK2/iso:4


"A focal adhesion kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P34152-4 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O35346-1

focal adhesion kinase 1 isoform 1 (rat)

rPTK2/iso:1


"A focal adhesion kinase 1 isoform 4 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000049946

focal adhesion kinase 1 isoform 1 phosphorylated 1 (rat)

rPTK2/iso:1/Phos:1


"A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated on the residue at the position equivalent to Tyr-397. UniProtKB:O35346-1, Tyr-397, MOD:00048." [PMID:27994061, PRO:LN]


organism-modification



PR:000049947

focal adhesion kinase 1 isoform 1 unphosphorylated 1 (rat)

rPTK2/iso:1/UnPhos:1


"A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at the position equivalent to Tyr-397. UniProtKB:O35346-1, Tyr-397, PR:000026291." [PMID:27994061, PRO:LN]


organism-modification



PR:000049948

focal adhesion kinase 1 isoform 1 phosphorylated 2 (rat)

rPTK2/iso:1/Phos:2


"A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated at positions equivalent to Tyr-576 and Tyr-577. UniProtKB:O35346-1, Tyr-576/Tyr-577, MOD:00048." [PMID:27994061, PRO:LN]


organism-modification



PR:000049949

focal adhesion kinase 1 isoform 1 unphosphorylated 2 (rat)

rPTK2/iso:1/UnPhos:2


"A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at positions equivalent to Tyr-576 and Tyr-577. UniProtKB:O35346-1, Tyr-576/Tyr-577, PR:000026291." [PMID:27994061, PRO:LN]


organism-modification



PR:000049950

focal adhesion kinase 1 isoform 1 phosphorylated 3 (rat)

rPTK2/iso:1/Phos:3


"A focal adhesion kinase 1 isoform 1 (rat) that has been phosphorylated on the residue at the position equivalent to Tyr-928. UniProtKB:O35346-1, Tyr-928, MOD:00048." [PMID:27994061, PRO:LN]


organism-modification



PR:000049951

focal adhesion kinase 1 isoform 1 unphosphorylated 3 (rat)

rPTK2/iso:1/UnPhos:3


"A focal adhesion kinase 1 isoform 1 (rat) that lacks phosphorylation at the position equivalent to Tyr-928. UniProtKB:O35346-1, Tyr-928, PR:000026291." [PMID:27994061, PRO:LN]


organism-sequence



PR:P34152-4

focal adhesion kinase 1 isoform 4 (mouse)

mPTK2/iso:4


"A focal adhesion kinase 1 isoform 4 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000018781

focal adhesion kinase 1, initiator methionine removed form

PTK2/InitMet-


"A focal adhesion kinase 1 that has had the initiator methionine removed." [PRO:DNx]


modification



PR:000026199

focal adhesion kinase 1, initiator methionine removed phosphorylated 1

PTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed form that has been phosphorylated on a residue at the position equivalent to Tyr-397 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, Tyr-397, MOD:00048." [PRO:CNx, Reactome:R-HSA-354068]


organism-modification



PR:000026219

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (human)

hPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397, MOD:00048." [PRO:CNx, Reactome:R-HSA-354068]


organism-modification



PR:000049944

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (mouse)

mPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in mouse. UniProtKB:P34152, 2-1052, Tyr-397, MOD:00048." [PMID:27994061, PRO:DAN, PRO:LN]


modification



PR:000026200

focal adhesion kinase 1, initiator methionine removed phosphorylated 2

PTK2/InitMet-/Phos:2


"A focal adhesion kinase 1, initiator methionine removed form that has been phosphorylated on residues at positions equivalent to Tyr-407, Tyr-576, Tyr-577, Tyr-861, and Tyr-925 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-354128]


organism-modification



PR:000026218

focal adhesion kinase 1, initiator methionine removed phosphorylated 2 (human)

hPTK2/InitMet-/Phos:2


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 2 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-354128]


modification



PR:000026628

focal adhesion kinase 1 isoform 1, initiator methionine removed form

PTK2/iso:1/InitMet-


"A focal adhesion kinase 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000048949

focal adhesion kinase 1, initiator methionine removed form (human)

hPTK2/InitMet-


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed. UniProtKB:Q05397, 2-1052." [PRO:DNx, Reactome:R-HSA-201621]


organism-modification



PR:000062510

focal adhesion kinase 1, initiator methionine removed phosphotyrosine form (human)

hPTK2/InitMet-/PhosTyr+


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that includes at least one phosphorylated tyrosine. Example: UniProtKB:Q05397-1, 2-1052, MOD:00048." [PRO:DNx, Reactome:R-HSA-9632393]


organism-modification



PR:000026218

focal adhesion kinase 1, initiator methionine removed phosphorylated 2 (human)

hPTK2/InitMet-/Phos:2


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 2 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:CNA, PRO:DAN, Reactome:R-HSA-354128]


organism-modification



PR:000026219

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (human)

hPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in human. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397, MOD:00048." [PRO:CNx, Reactome:R-HSA-354068]


organism-modification



PR:000048950

focal adhesion kinase 1, initiator methionine removed phosphorylated 3 (human)

hPTK2/InitMet-/Phos:3


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 407, 576, 577, 861 and 925, and phosphoserine at position 732 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-407/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048|Ser-732, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218694]


organism-modification



PR:000048951

focal adhesion kinase 1, initiator methionine removed phosphorylated 4 (human)

hPTK2/InitMet-/Phos:4


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 576, 577, 861 and 925 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218711]


organism-modification



PR:000048952

focal adhesion kinase 1, initiator methionine removed phosphorylated 5 (human)

hPTK2/InitMet-/Phos:5


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at positions 397, 576, 577, 861 and 925, and phosphoserine at position 732 of the amino acid sequence represented by UniProtKB:Q05397. UniProtKB:Q05397, 2-1052, Tyr-397/Tyr-576/Tyr-577/Tyr-861/Tyr-925, MOD:00048|Ser-732, MOD:00046." [PRO:DNx, Reactome:R-HSA-5229006]


organism-modification



PR:000062394

focal adhesion kinase 1, initiator methionine removed phosphorylated 6 (human)

hPTK2/InitMet-/Phos:6


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-194 and Tyr-397 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-194/Tyr-397, MOD:00048." [PRO:DNx, Reactome:R-HSA-8874600]


organism-modification



PR:000063617

focal adhesion kinase 1, initiator methionine removed phosphorylated 7 (human)

hPTK2/InitMet-/Phos:7


"A focal adhesion kinase 1 (human) that has had the initiator methionine removed and that has been phosphorylated on the residues at the positions equivalent to Tyr-194, Tyr-397, Tyr-576, and Tyr-577 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-194/Tyr-397/Tyr-576/Tyr-577, MOD:00048." [PRO:DNx, Reactome:R-HSA-8874613]


organism-modification



PR:000049943

focal adhesion kinase 1, initiator methionine removed form (mouse)

mPTK2/InitMet-


"A focal adhesion kinase 1 (mouse) that has had the initiator methionine removed. UniProtKB:P34152, 2-1052." [PRO:CNA, UniProtKB:P34152]


organism-modification



PR:000049944

focal adhesion kinase 1, initiator methionine removed phosphorylated 1 (mouse)

mPTK2/InitMet-/Phos:1


"A focal adhesion kinase 1, initiator methionine removed phosphorylated 1 in mouse. UniProtKB:P34152, 2-1052, Tyr-397, MOD:00048." [PMID:27994061, PRO:DAN, PRO:LN]


organism-modification



PR:000049945

focal adhesion kinase 1, initiator methionine removed unphosphorylated 1 (mouse)

mPTK2/InitMet-/UnPhos:1


"A focal adhesion kinase 1, initiator methionine removed form (mouse) that lacks phosphorylation on the residue at the position equivalent to Tyr-397 of the amino acid sequence represented by UniProtKB:Q05397-1. Example: UniProtKB:Q05397-1, 2-1052, Tyr-397, PR:000026291." [PMID:27994061, PRO:LN]


gene



PR:000003032

focal adhesion kinase 2

PTK2B


"A focal adhesion kinase that is a translation product of the human PTK2B gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P70600

protein-tyrosine kinase 2-beta (rat)

rPTK2B


"A focal adhesion kinase 2 that is encoded in the genome of rat." [OMA:P70600, PRO:DNx]


organism-sequence



PR:P70600-1

protein-tyrosine kinase 2-beta isoform r1 (rat)

rPTK2B/iso:r1


"A protein-tyrosine kinase 2-beta (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70600-1." [PRO:DNx, UniProtKB:P70600]


organism-sequence



PR:P70600-2

protein-tyrosine kinase 2-beta isoform r2 (rat)

rPTK2B/iso:r2


"A protein-tyrosine kinase 2-beta (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70600-2." [PRO:DNx, UniProtKB:P70600]


organism-sequence



PR:P70600-3

protein-tyrosine kinase 2-beta isoform 3 (rat)

rPTK2B/iso:3


"A focal adhesion kinase 2 isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q14289

protein-tyrosine kinase 2-beta (human)

hPTK2B


"A focal adhesion kinase 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q14289]


organism-sequence



PR:Q14289-1

protein-tyrosine kinase 2-beta isoform 1 (human)

hPTK2B/iso:1


"A focal adhesion kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036642

focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)

hPTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]

Yes

organism-sequence



PR:Q14289-2

protein-tyrosine kinase 2-beta isoform 2 (human)

hPTK2B/iso:2


"A focal adhesion kinase 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000048954

protein-tyrosine kinase 2-beta phosphotyrosine form (human)

hPTK2B/PhosTyr+


"A protein-tyrosine kinase 2-beta (human) that includes at least one phosphorylated tyrosine. UniProtKB:Q14289, MOD:00048." [PRO:DNx, Reactome:R-HSA-508515]


organism-modification



PR:000036642

focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)

hPTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]

Yes

organism-modification



PR:000048953

protein-tyrosine kinase 2-beta phosphorylated 2 (human)

hPTK2B/Phos:2


"A protein-tyrosine kinase 2-beta (human) that has been phosphorylated on the residue at the position equivalent to Tyr-402 of the amino acid sequence represented by UniProtKB:Q14289. UniProtKB:Q14289, Tyr-402, MOD:00048." [PRO:DNx, Reactome:R-HSA-5218721]


organism-modification



PR:000065247

protein-tyrosine kinase 2-beta methylated 1 (human)

hPTK2B/Me:1


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-246 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-246, MOD:00660." [IEDB_epitope:1002474, PRO:DNx]


organism-modification



PR:000070234

protein-tyrosine kinase 2-beta cysteinylated 1 (human)

hPTK2B/Cyst:1


"A protein-tyrosine kinase 2-beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-246 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-246, MOD:00765." [IEDB_epitope:1587468, PRO:DNx]


organism-modification



PR:000071896

protein-tyrosine kinase 2-beta deaminated 1 (human)

hPTK2B/Deam:1


"A protein-tyrosine kinase 2-beta (human) that has been deaminated on the residue at the position equivalent to Gln-329 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Gln-329, MOD:00685." [IEDB_epitope:1349689, PRO:DNx]


organism-modification



PR:000077476

protein-tyrosine kinase 2-beta deaminated 2 (human)

hPTK2B/Deam:2


"A protein-tyrosine kinase 2-beta (human) that has been deaminated on the residue at the position equivalent to Asn-193 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Asn-193, MOD:00684." [IEDB_epitope:635229, PRO:DNx]


organism-modification



PR:000078700

protein-tyrosine kinase 2-beta methylated 2 (human)

hPTK2B/Me:2


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-534 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-534, MOD:00660." [IEDB_epitope:1058353, PRO:DNx]


organism-modification



PR:000079503

protein-tyrosine kinase 2-beta methylated 3 (human)

hPTK2B/Me:3


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-120 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-120, MOD:00660." [IEDB_epitope:1010336, IEDB_epitope:1015039, PRO:DNx]


organism-modification



PR:000081549

protein-tyrosine kinase 2-beta methylated 4 (human)

hPTK2B/Me:4


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-298 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-298, MOD:00660." [IEDB_epitope:1051088, PRO:DNx]


organism-modification



PR:000083633

protein-tyrosine kinase 2-beta cysteinylated 2 (human)

hPTK2B/Cyst:2


"A protein-tyrosine kinase 2-beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-534 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-534, MOD:00765." [IEDB_epitope:1031252, IEDB_epitope:638607, PRO:DNx]


organism-modification



PR:000083918

protein-tyrosine kinase 2-beta phosphorylated 1 (human)

hPTK2B/Phos:1


"A protein-tyrosine kinase 2-beta (human) that has been phosphorylated on the residue at the position equivalent to Ser-530 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Ser-530, MOD:00046." [IEDB_epitope:1374869, PRO:DNx]


organism-modification



PR:000085313

protein-tyrosine kinase 2-beta methylated 5 (human)

hPTK2B/Me:5


"A protein-tyrosine kinase 2-beta (human) that has been methylated on the residue at the position equivalent to Cys-310 of the amino acid sequence represented by UniProtKB:Q14289-1. Example: UniProtKB:Q14289-1, Cys-310, MOD:00660." [IEDB_epitope:1026113, PRO:DNx]


organism-gene



PR:Q9QVP9

protein-tyrosine kinase 2-beta (mouse)

mPTK2B


"A focal adhesion kinase 2 that is encoded in the genome of mouse." [OMA:Q9QVP9, PRO:DNx]


organism-modification



PR:000079444

protein-tyrosine kinase 2-beta cysteinylated 1 (mouse)

mPTK2B/Cyst:1


"A protein-tyrosine kinase 2-beta (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-545 of the amino acid sequence represented by UniProtKB:Q9QVP9. UniProtKB:Q9QVP9, Cys-545, MOD:00765." [IEDB_epitope:2089144, IEDB_epitope:2115153, PRO:DNx]


sequence



PR:000003239

focal adhesion kinase 2 isoform 1

PTK2B/iso:1


"A focal adhesion kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14289-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:Q14289-1

protein-tyrosine kinase 2-beta isoform 1 (human)

hPTK2B/iso:1


"A focal adhesion kinase 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000036642

focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)

hPTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]

Yes

modification



PR:000003241

focal adhesion kinase 2 isoform 1 phosphorylated form

PTK2B/iso:1/PhosRes+


"A focal adhesion kinase 2 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003242

focal adhesion kinase 2 isoform 1 phosphorylated 1

PTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated form in which the phosphorylation occurs at the Tyr residues that yield the active kinase. Example: UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]


organism-modification



PR:000036642

focal adhesion kinase 2 isoform 1 phosphorylated 1 (human)

hPTK2B/iso:1/Phos:1


"A focal adhesion kinase 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048." [PMID:11698270, PRO:CL]

Yes

sequence



PR:000040522

focal adhesion kinase 2 isoform 2

PTK2B/iso:2


"A focal adhesion kinase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14289-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P70600-3

protein-tyrosine kinase 2-beta isoform 3 (rat)

rPTK2B/iso:3


"A focal adhesion kinase 2 isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q14289-2

protein-tyrosine kinase 2-beta isoform 2 (human)

hPTK2B/iso:2


"A focal adhesion kinase 2 isoform 2 that is encoded in the genome of human." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036642 hPTK2B/iso:1/Phos:1
UniProtKB:Q14289-1, Tyr-402/Tyr-579/Tyr-580/Tyr-881, MOD:00048
acts_upstream_of_or_withinGO:0070098 chemokine-mediated signaling pathway PMID:11698270