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Protein Ontology report - caspase-8 isoform 1
PR:000002412 - http://purl.obolibrary.org/obo/PR_000002412
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002412   
  PRO namecaspase-8 isoform 1 
  Synonyms
PRO-Short-label: EXACT:CASP8/iso:1
Other: EXACT:caspase-8 isoform alpha-1
  Definition"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-1 or a 1:1 ortholog thereof." [PRO:JAN] 
  PRO Categorysequence 
  ParentPR:000002317 caspase-8
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000002412
caspase-8 isoform 1
CASP8/iso:1
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-1 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:O89110-1
caspase-8 isoform 1 (mouse)
mCASP8/iso:1
"A caspase-8 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]

organism-sequence


PR:Q14790-1
caspase-8 isoform 1 (human)
hCASP8/iso:1
"A caspase-8 isoform 1 that is encoded in the genome of human." [PRO:JAN]

organism-modification


PR:000036063
caspase-8 isoform 1 cleaved 1 (human)
hCASP8/iso:1/Clv:1
"A caspase-8 isoform 1 cleaved 1 in human. UniProtKB:Q14790-1, 217-374." [PMID:9184224, PRO:CNA]

Yes
organism-modification


PR:000036065
caspase-8 isoform 1 cleaved 2 (human)
hCASP8/iso:1/Clv:2
"A caspase-8 isoform 1 cleaved 2 in human. UniProtKB:Q14790-1, 385-479." [PMID:9184224, PRO:CNA]

Yes
modification


PR:000036062
caspase-8 isoform 1 cleaved 1
CASP8/iso:1/Clv:1
"A caspase-8 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-8 subunit p18." [PRO:CNA]

organism-modification


PR:000036063
caspase-8 isoform 1 cleaved 1 (human)
hCASP8/iso:1/Clv:1
"A caspase-8 isoform 1 cleaved 1 in human. UniProtKB:Q14790-1, 217-374." [PMID:9184224, PRO:CNA]

Yes
modification


PR:000036064
caspase-8 isoform 1 cleaved 2
CASP8/iso:1/Clv:2
"A caspase-8 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-8 subunit p10." [PRO:CNA]

organism-modification


PR:000036065
caspase-8 isoform 1 cleaved 2 (human)
hCASP8/iso:1/Clv:2
"A caspase-8 isoform 1 cleaved 2 in human. UniProtKB:Q14790-1, 385-479." [PMID:9184224, PRO:CNA]

Yes
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CASP8/iso:1 forms found in complexes   

CASP8/iso:1 Component
 Complexes
PR:000036063 hCASP8/iso:1/Clv:1 PR:000036068 caspase-8 complex (human)
PR:000036065 hCASP8/iso:1/Clv:2 PR:000036068 caspase-8 complex (human)