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Protein Ontology report - caspase-2 isoform 1
PR:000002400 - http://purl.obolibrary.org/obo/PR_000002400
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000002400   
  PRO namecaspase-2 isoform 1 
  Synonyms
PRO-Short-label: EXACT:CASP2/iso:1
Other: EXACT:caspase-2 isoform ICH-1L
  Definition"A caspase-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-1 or a 1:1 ortholog thereof. This isoform acts as a positive regulator of apoptosis." [PRO:JAN] 
  PRO Categorysequence 
  ParentPR:000002311 caspase-2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000002400

caspase-2 isoform 1

CASP2/iso:1


"A caspase-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-1 or a 1:1 ortholog thereof. This isoform acts as a positive regulator of apoptosis." [PRO:JAN]


organism-sequence



PR:P29594-1

caspase-2 isoform 1 (mouse)

mCASP2/iso:1


"A caspase-2 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]


organism-sequence



PR:P42575-1

caspase-2 isoform 1 (human)

hCASP2/iso:1


"A caspase-2 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000050110

caspase-2 subunit p18 (human)

hCASP2/p18


"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]


organism-modification



PR:000050111

caspase-2 subunit p13 (human)

hCASP2/p13


"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]


organism-modification



PR:000050112

caspase-2 subunit p12 (human)

hCASP2/p12


"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]


modification



PR:000002451

caspase-2 subunit p18

CASP2/p18


"A caspase-2 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P42575-1, 170-325." [PMID:8654923, PRO:DAN, PRO:JAN]


organism-modification



PR:000050110

caspase-2 subunit p18 (human)

hCASP2/p18


"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]


modification



PR:000002452

caspase-2 subunit p13

CASP2/p13


"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. UniProtKB:P42575-1, 334-452." [PMID:8654923, PRO:DAN, PRO:JAN]


organism-modification



PR:000050111

caspase-2 subunit p13 (human)

hCASP2/p13


"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]


modification



PR:000002453

caspase-2 subunit p12

CASP2/p12


"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides and a short intersubunit linker (in humans, the N-terminal-most 14 amino acids of the p13 form). UniProtKB:P42575-1, 348-452." [PMID:8654923, PRO:DAN, PRO:JAN]


organism-modification



PR:000050112

caspase-2 subunit p12 (human)

hCASP2/p12


"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]