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Protein Ontology report - caspase-3
PR:000002312 - http://purl.obolibrary.org/obo/PR_000002312
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002312   
  PRO namecaspase-3 
  Synonyms
PRO-Short-label: EXACT:CASP3
Gene-based: RELATED:CPP32
Other: EXACT:apopain | CASP-3 | CPP-32 | cysteine protease CPP32 | LICE | protein Yama | SREBP cleavage activity 1
RELATED:SCA-1
  Definition"A caspase-3-like protease that is a translation product of the human CASP3 gene or a 1:1 ortholog thereof." [PRO:JAN] 
  PRO Categorygene 
  ParentPR:000002196 caspase-3-like protease
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1619
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000002312

caspase-3

CASP3


"A caspase-3-like protease that is a translation product of the human CASP3 gene or a 1:1 ortholog thereof." [PRO:JAN]


organism-gene



PR:P42574

caspase-3 (human)

hCASP3


"A caspase-3 that is encoded in the genome of human." [PRO:JAN, UniProtKB:P42574]


organism-sequence



PR:P42574-1

caspase-3 isoform 1 (human)

hCASP3/iso:1


"A caspase-3 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000026876

caspase-3 isoform 1 cleaved 1 (human)

hCASP3/iso:1/Clv:1


"A caspase-3 isoform 1 cleaved 1 in human. UniProtKB:P42574-1, 176-277." [PMID:11931755, PRO:CNA]


Yes
organism-modification



PR:000026877

caspase-3 isoform 1 cleaved 2 (human)

hCASP3/iso:1/Clv:2


"A caspase-3 isoform 1 cleaved 2 in human. UniProtKB:P42574-1, 29-175." [PRO:CNA]


Yes
organism-modification



PR:000082245

caspase-3 cysteinylated 1 (human)

hCASP3/Cyst:1


"A caspase-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-148 of the amino acid sequence represented by UniProtKB:P42574. UniProtKB:P42574, Cys-148, MOD:00765." [IEDB_epitope:925902, PRO:DNx]


organism-gene



PR:P55213

caspase-3 (rat)

rCASP3


"A caspase-3 that is encoded in the genome of rat." [OMA:P55213, PRO:DNx]


organism-gene



PR:P70677

caspase-3 (mouse)

mCASP3


"A caspase-3 that is encoded in the genome of mouse." [OMA:P70677, PRO:DNx]


organism-sequence



PR:P70677-1

caspase-3 isoform 1 (mouse)

mCASP3/iso:1


"A caspase-3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


organism-gene



PR:Q8MKI5

caspase-3 (dog)

dog-CASP3


"A caspase-3 that is encoded in the genome of dog." [OMA:Q8MKI5, PRO:DNx]


sequence



PR:000002402

caspase-3 isoform 1

CASP3/iso:1


"A caspase-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70677-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P42574-1

caspase-3 isoform 1 (human)

hCASP3/iso:1


"A caspase-3 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000026876

caspase-3 isoform 1 cleaved 1 (human)

hCASP3/iso:1/Clv:1


"A caspase-3 isoform 1 cleaved 1 in human. UniProtKB:P42574-1, 176-277." [PMID:11931755, PRO:CNA]


Yes
organism-modification



PR:000026877

caspase-3 isoform 1 cleaved 2 (human)

hCASP3/iso:1/Clv:2


"A caspase-3 isoform 1 cleaved 2 in human. UniProtKB:P42574-1, 29-175." [PRO:CNA]


Yes
organism-sequence



PR:P70677-1

caspase-3 isoform 1 (mouse)

mCASP3/iso:1


"A caspase-3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]


modification



PR:000002454

caspase-3 isoform 1 cleaved 1

CASP3/iso:1/Clv:1


"A caspase-3 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-3 subunit p12." [PRO:CNA]


Yes
organism-modification



PR:000026876

caspase-3 isoform 1 cleaved 1 (human)

hCASP3/iso:1/Clv:1


"A caspase-3 isoform 1 cleaved 1 in human. UniProtKB:P42574-1, 176-277." [PMID:11931755, PRO:CNA]


Yes
modification



PR:000002455

caspase-3 isoform 1 cleaved 2

CASP3/iso:1/Clv:2


"A caspase-3 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-3 subunit p17." [PRO:CNA]


Yes
organism-modification



PR:000026877

caspase-3 isoform 1 cleaved 2 (human)

hCASP3/iso:1/Clv:2


"A caspase-3 isoform 1 cleaved 2 in human. UniProtKB:P42574-1, 29-175." [PRO:CNA]


Yes
modification



PR:000018762

caspase-3 proteolytic cleavage product

CASP3/ClvPrd


"A caspase-3 that has been processed by proteolytic cleavage." [PRO:DNx]


modification



PR:000002454

caspase-3 isoform 1 cleaved 1

CASP3/iso:1/Clv:1


"A caspase-3 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-3 subunit p12." [PRO:CNA]


Yes
organism-modification



PR:000026876

caspase-3 isoform 1 cleaved 1 (human)

hCASP3/iso:1/Clv:1


"A caspase-3 isoform 1 cleaved 1 in human. UniProtKB:P42574-1, 176-277." [PMID:11931755, PRO:CNA]


Yes
modification



PR:000002455

caspase-3 isoform 1 cleaved 2

CASP3/iso:1/Clv:2


"A caspase-3 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-3 subunit p17." [PRO:CNA]


Yes
organism-modification



PR:000026877

caspase-3 isoform 1 cleaved 2 (human)

hCASP3/iso:1/Clv:2


"A caspase-3 isoform 1 cleaved 2 in human. UniProtKB:P42574-1, 29-175." [PRO:CNA]


Yes
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CASP3 forms found in complexes   

CASP3 Component
Complexes
PR:000002454 CASP3/iso:1/Clv:1 PR:000026878 caspase-3 complex
PR:000002455 CASP3/iso:1/Clv:2 PR:000026878 caspase-3 complex
PR:000026876 hCASP3/iso:1/Clv:1 PR:000026879 caspase-3 complex (human)
PR:000026877 hCASP3/iso:1/Clv:2 PR:000026879 caspase-3 complex (human)