|
|
 |
|
| | |
| | | | | | |
gene
|
|
PR:000002311 |
caspase-2
|
CASP2
|
"A caspase-1-like protease that is a translation product of the human CASP2 gene or a 1:1 ortholog thereof. This protein is involved in the activation cascade of caspases responsible for apoptosis execution." [PRO:WCB]
|
|
|
|
|
|
|
| | | | |
| | | | |
organism-gene
|
|
PR:P29594 |
caspase-2 (mouse)
|
mCASP2
|
"A caspase-2 that is encoded in the genome of mouse." [OMA:P29594, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P29594-1 |
caspase-2 isoform 1 (mouse)
|
mCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | |
| | | | |
organism-gene
|
|
PR:P42575 |
caspase-2 (human)
|
hCASP2
|
"A caspase-2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P42575-1 |
caspase-2 isoform 1 (human)
|
hCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P42575-2 |
caspase-2 isoform 2 (human)
|
hCASP2/iso:2
|
"A caspase-2 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P42575-3 |
caspase-2 isoform h3 (human)
|
hCASP2/iso:h3
|
"A caspase-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-3." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-modification
|
|
PR:000045782 |
caspase-2 phosphorylated 1 (human)
|
hCASP2/Phos:1
|
"A caspase-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-157 of the amino acid sequence represented by UniProtKB:P42575-1. Example: UniProtKB:P42575-1, Ser-157, MOD:00046." [iPTMnet:P42575, PMID:16193064]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-modification
|
|
PR:000046570 |
caspase-2, initiator methionine removed form (human)
|
hCASP2/InitMet-
|
"A caspase-2 (human) that has had the initiator methionine removed. UniProtKB:P42575, 2-452." [PRO:DNx, Reactome:R-HSA-622412]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-modification
|
|
PR:000070230 |
caspase-2 methylated 1 (human)
|
hCASP2/Me:1
|
"A caspase-2 (human) that has been methylated on the residue at the position equivalent to Cys-436 of the amino acid sequence represented by UniProtKB:P42575-1. Example: UniProtKB:P42575-1, Cys-436, MOD:00660." [IEDB_epitope:1023721, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-modification
|
|
PR:000080352 |
caspase-2 methylated 2 (human)
|
hCASP2/Me:2
|
"A caspase-2 (human) that has been methylated on the residue at the position equivalent to Cys-270 of the amino acid sequence represented by UniProtKB:P42575-1. Example: UniProtKB:P42575-1, Cys-270, MOD:00660." [IEDB_epitope:1059558, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | |
organism-gene
|
|
PR:P55215 |
caspase-2 (rat)
|
rCASP2
|
"A caspase-2 that is encoded in the genome of rat." [OMA:P55215, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P55215-1 |
caspase-2 isoform r1 (rat)
|
rCASP2/iso:r1
|
"A caspase-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55215-1." [PRO:DNx, UniProtKB:P55215]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P55215-2 |
caspase-2 isoform r2 (rat)
|
rCASP2/iso:r2
|
"A caspase-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55215-2." [PRO:DNx, UniProtKB:P55215]
|
|
|
|
|
|
|
| | | | |
| | | | |
organism-gene
|
|
PR:Q98943 |
caspase-2 (chicken)
|
chick-CASP2
|
"A caspase-2 that is encoded in the genome of chicken." [OMA:Q98943, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:Q98943-1 |
caspase-2 isoform ICH-1L (chicken)
|
chick-CASP2/iso:ICH-1L
|
"A caspase-2 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q98943-1." [PRO:DNx, UniProtKB:Q98943]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:Q98943-2 |
caspase-2 isoform ICH-1S (chicken)
|
chick-CASP2/iso:ICH-1S
|
"A caspase-2 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q98943-2." [PRO:DNx, UniProtKB:Q98943]
|
|
|
|
|
|
|
| | | | |
| | | | |
organism-gene
|
|
PR:Q9XYF4 |
caspase Dronc (fruit fly)
|
fly-CASP2
|
"A caspase-2 that is encoded in the genome of fruit fly." [OMA:Q9XYF4, PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | |
sequence
|
|
PR:000002400 |
caspase-2 isoform 1
|
CASP2/iso:1
|
"A caspase-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-1 or a 1:1 ortholog thereof. This isoform acts as a positive regulator of apoptosis." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P29594-1 |
caspase-2 isoform 1 (mouse)
|
mCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P42575-1 |
caspase-2 isoform 1 (human)
|
hCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
modification
|
|
PR:000002451 |
caspase-2 subunit p18
|
CASP2/p18
|
"A caspase-2 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P42575-1, 170-325." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
modification
|
|
PR:000002452 |
caspase-2 subunit p13
|
CASP2/p13
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. UniProtKB:P42575-1, 334-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
modification
|
|
PR:000002453 |
caspase-2 subunit p12
|
CASP2/p12
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides and a short intersubunit linker (in humans, the N-terminal-most 14 amino acids of the p13 form). UniProtKB:P42575-1, 348-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | |
| | | | |
sequence
|
|
PR:000002401 |
caspase-2 isoform 2
|
CASP2/iso:2
|
"A caspase-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-2 or a 1:1 ortholog thereof. This isoform acts as a negative regulator of apoptosis." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-sequence
|
|
PR:P42575-2 |
caspase-2 isoform 2 (human)
|
hCASP2/iso:2
|
"A caspase-2 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | |
| | | | |
modification
|
|
PR:000018760 |
caspase-2, initiator methionine removed form
|
CASP2/InitMet-
|
"A caspase-2 that has had the initiator methionine removed." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
organism-modification
|
|
PR:000046570 |
caspase-2, initiator methionine removed form (human)
|
hCASP2/InitMet-
|
"A caspase-2 (human) that has had the initiator methionine removed. UniProtKB:P42575, 2-452." [PRO:DNx, Reactome:R-HSA-622412]
|
|
|
|
|
|
|
| | | | |
| | | | |
modification
|
|
PR:000018761 |
caspase-2 proteolytic cleavage product
|
CASP2/ClvPrd
|
"A caspase-2 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | |
modification
|
|
PR:000002451 |
caspase-2 subunit p18
|
CASP2/p18
|
"A caspase-2 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P42575-1, 170-325." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
modification
|
|
PR:000002452 |
caspase-2 subunit p13
|
CASP2/p13
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. UniProtKB:P42575-1, 334-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | |
modification
|
|
PR:000002453 |
caspase-2 subunit p12
|
CASP2/p12
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides and a short intersubunit linker (in humans, the N-terminal-most 14 amino acids of the p13 form). UniProtKB:P42575-1, 348-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
|
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
