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gene
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PR:000002309 |
caspase-1
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CASP1
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"A caspase-1-like protease that is a translation product of the human CASP1 gene or a 1:1 ortholog thereof. The active form of this protein proteolytically cleaves pro-IL-1beta to its mature, active form. The holoenzyme is a homodimer of catalytic domains, each of which contains the cleaved products caspase-1 p20 and p10 subunits." [PMID:8044845, PRO:WCB]
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organism-gene
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PR:P29452 |
caspase-1 (mouse)
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mCASP1
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"A caspase-1 that is encoded in the genome of mouse." [OMA:P29452, PRO:DNx]
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organism-sequence
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PR:P29452-1 |
caspase-1 isoform 1 (mouse)
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mCASP1/iso:1
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"A caspase-1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
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organism-modification
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PR:000078346 |
caspase-1 cysteinylated 1 (mouse)
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mCASP1/Cyst:1
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"A caspase-1 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-168 of the amino acid sequence represented by UniProtKB:P29452. UniProtKB:P29452, Cys-168, MOD:00765." [IEDB_epitope:2089306, PRO:DNx]
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organism-gene
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PR:P29466 |
caspase-1 (human)
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hCASP1
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"A caspase-1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P29466]
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organism-sequence
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PR:P29466-1 |
caspase-1 isoform alpha (human)
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hCASP1/iso:alpha
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"A caspase-1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
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organism-sequence
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PR:P29466-2 |
caspase-1 isoform beta (human)
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hCASP1/iso:beta
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"A caspase-1 isoform 2 that is encoded in the genome of human." [PRO:JAN]
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organism-sequence
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PR:P29466-3 |
caspase-1 isoform gamma (human)
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hCASP1/iso:gamma
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"A caspase-1 isoform 3 that is encoded in the genome of human." [PRO:JAN]
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organism-sequence
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PR:P29466-4 |
caspase-1 isoform delta (human)
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hCASP1/iso:delta
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"A caspase-1 isoform 4 that is encoded in the genome of human." [PRO:JAN]
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organism-sequence
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PR:P29466-5 |
caspase-1 isoform epsilon (human)
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hCASP1/iso:epsilon
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"A caspase-1 isoform 5 that is encoded in the genome of human." [PRO:JAN]
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organism-modification
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PR:000079348 |
caspase-1 cysteinylated 1 (human)
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hCASP1/Cyst:1
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"A caspase-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-136 of the amino acid sequence represented by UniProtKB:P29466-1. Example: UniProtKB:P29466-1, Cys-136, MOD:00765." [IEDB_epitope:924947, PRO:DNx]
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organism-gene
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PR:P43527 |
caspase-1 (rat)
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rCASP1
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"A caspase-1 that is encoded in the genome of rat." [OMA:P43527, PRO:DNx]
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sequence
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PR:000002390 |
caspase-1 isoform 1
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CASP1/iso:1
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"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-1 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
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PR:P29452-1 |
caspase-1 isoform 1 (mouse)
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mCASP1/iso:1
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"A caspase-1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
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organism-sequence
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PR:P29466-1 |
caspase-1 isoform alpha (human)
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hCASP1/iso:alpha
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"A caspase-1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
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modification
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PR:000002449 |
caspase-1 isoform 1 cleaved 1
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CASP1/iso:1/Clv:1
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"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p20." [PMID:8044845, PRO:JAN]
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modification
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PR:000002450 |
caspase-1 isoform 1 cleaved 2
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CASP1/iso:1/Clv:2
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"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p10." [PMID:8044845, PRO:JAN]
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sequence
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PR:000002391 |
caspase-1 isoform 2
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CASP1/iso:2
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"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-2 or a 1:1 ortholog thereof." [PMID:15489334, PRO:JAN]
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organism-sequence
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PR:P29466-2 |
caspase-1 isoform beta (human)
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hCASP1/iso:beta
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"A caspase-1 isoform 2 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002392 |
caspase-1 isoform 3
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CASP1/iso:3
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"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-3 or a 1:1 ortholog thereof." [PMID:15489334, PRO:JAN]
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organism-sequence
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PR:P29466-3 |
caspase-1 isoform gamma (human)
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hCASP1/iso:gamma
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"A caspase-1 isoform 3 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002393 |
caspase-1 isoform 4
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CASP1/iso:4
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"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-4 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
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PR:P29466-4 |
caspase-1 isoform delta (human)
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hCASP1/iso:delta
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"A caspase-1 isoform 4 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002394 |
caspase-1 isoform 5
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CASP1/iso:5
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"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-5 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
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PR:P29466-5 |
caspase-1 isoform epsilon (human)
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hCASP1/iso:epsilon
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"A caspase-1 isoform 5 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002395 |
caspase-1 isoform 6
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CASP1/iso:6
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"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-1, 40-404 or a 1:1 ortholog thereof." [PMID:15498465, PRO:JAN]
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modification
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PR:000018758 |
caspase-1 proteolytic cleavage product
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CASP1/ClvPrd
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"A caspase-1 that has been processed by proteolytic cleavage." [PRO:DNx]
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modification
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PR:000002449 |
caspase-1 isoform 1 cleaved 1
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CASP1/iso:1/Clv:1
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"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p20." [PMID:8044845, PRO:JAN]
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modification
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PR:000002450 |
caspase-1 isoform 1 cleaved 2
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CASP1/iso:1/Clv:2
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"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p10." [PMID:8044845, PRO:JAN]
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