back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - Bcl-2-like protein 1
PR:000002308 - http://purl.obolibrary.org/obo/PR_000002308
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002308   
  PRO nameBcl-2-like protein 1 
  Synonyms
PRO-Short-label: EXACT:BCL2L1
Gene-based: RELATED:BCL2L | BCLX
Other: EXACT:apoptosis regulator Bcl-X | Bcl2-L-1
  Definition"A Bcl-2-like apoptosis inhibitor that is a translation product of the human BCL2L1 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000002186 Bcl-2-like apoptosis inhibitor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence5                                                  Organism-Sequence 12                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:2845
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002308
Bcl-2-like protein 1
BCL2L1
"A Bcl-2-like apoptosis inhibitor that is a translation product of the human BCL2L1 gene or a 1:1 ortholog thereof." [PRO:WCB]

organism-gene


PR:P53563
Bcl-2-like protein 1 (rat)
rBCL2L1
"A Bcl-2-like protein 1 that is encoded in the genome of rat." [PRO:WCB]

organism-sequence


PR:P53563-1
Bcl-2-like protein 1 isoform Bcl-X(L) (rat)
rBcl2l1/iso:Bcl-X(L)
"A Bcl-2-like protein 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53563-1." [PRO:DNx, UniProtKB:P53563]

organism-sequence


PR:P53563-2
Bcl-2-like protein 1 isoform Bcl-X(S) (rat)
rBCL2L1/iso:Bcl-X(S)
"A Bcl-2-like protein 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53563-2." [PRO:DNx, UniProtKB:P53563]

organism-sequence


PR:P53563-3
Bcl-2-like protein 1 isoform Bcl-X(beta) (rat)
rBCL2L1/iso:Bcl-X(beta)
"A Bcl-2-like protein 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P53563-3." [PRO:DNx, UniProtKB:P53563]

organism-gene


PR:Q07816
Bcl-2-like protein 1 (chicken)
chick-BCL2L1
"A Bcl-2-like protein 1 that is encoded in the genome of chicken." [OMA:Q07816, PRO:DNx]

organism-sequence


PR:Q07816-1
Bcl-2-like protein 1 isoform Long (chicken)
chick-BCL2L1/iso:Long
"A Bcl-2-like protein 1 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07816-1." [PRO:DNx, UniProtKB:Q07816]

organism-sequence


PR:Q07816-2
Bcl-2-like protein 1 isoform Short (chicken)
chick-BCL2L1/iso:Short
"A Bcl-2-like protein 1 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07816-2." [PRO:DNx, UniProtKB:Q07816]

organism-gene


PR:Q07817
Bcl-2-like protein 1 (human)
hBCL2L1
"A Bcl-2-like protein 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q07817]

organism-sequence


PR:Q07817-1
Bcl-2-like protein 1 isoform 1 (human)
hBCL2L1/iso:1
"A Bcl-2-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-sequence


PR:Q07817-2
Bcl-2-like protein 1 isoform Bcl-X(S) (human)
hBCL2L1/iso:Bcl-X(S)
"A Bcl-2-like protein 1 isoform 2 that is encoded in the genome of human." [PRO:JAN]

organism-sequence


PR:Q07817-3
Bcl-2-like protein 1 isoform Bcl-X(beta) (human)
hBCL2L1/iso:Bcl-X(beta)
"A Bcl-2-like protein 1 isoform 3 that is encoded in the genome of human." [PRO:JAN]

organism-modification


PR:000045887
Bcl-2-like protein 1 phosphorylated 1 (human)
hBCL2L1/Phos:1
"A Bcl-2-like protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-62 of the amino acid sequence represented by UniProtKB:Q07817-1. Example: UniProtKB:Q07817-1, Ser-62, MOD:00046." [iPTMnet:Q07817, PMID:12633850]

organism-gene


PR:Q64373
Bcl-2-like protein 1 (mouse)
mBCL2L1
"A Bcl-2-like protein 1 that is encoded in the genome of mouse." [OMA:Q64373, PRO:DNx]

organism-sequence


PR:Q64373-1
Bcl-2-like protein 1 isoform Bcl-X(L) (mouse)
mBCL2L1/iso:Bcl-X(L)
"A Bcl-2-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
Yes
organism-sequence


PR:Q64373-2
Bcl-2-like protein 1 isoform Bcl-X(S) (mouse)
mBCL2L1/iso:Bcl-X(S)
"A Bcl-2-like protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:JAN]
Yes
organism-sequence


PR:Q64373-3
Bcl-2-like protein 1 isoform Bcl-X(beta) (mouse)
mBCL2L1/iso:Bcl-X(beta)
"A Bcl-2-like protein 1 isoform 4 that is encoded in the genome of mouse." [PRO:JAN]

organism-sequence


PR:Q64373-4
Bcl-2-like protein 1 isoform Bcl-X(delta-TM) (mouse)
mBCL2L1/iso:Bcl-X(delta-TM)
"A Bcl-2-like protein 1 isoform 5 that is encoded in the genome of mouse." [PRO:JAN]

sequence


PR:000002385
Bcl-2-like protein 1 isoform 1
BCL2L1/iso:1
"A Bcl-2-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64373-1 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q07817-1
Bcl-2-like protein 1 isoform 1 (human)
hBCL2L1/iso:1
"A Bcl-2-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
Yes
organism-sequence


PR:Q64373-1
Bcl-2-like protein 1 isoform Bcl-X(L) (mouse)
mBCL2L1/iso:Bcl-X(L)
"A Bcl-2-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
Yes
sequence


PR:000002386
Bcl-2-like protein 1 isoform 2
BCL2L1/iso:2
"A Bcl-2-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64373-2 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q07817-2
Bcl-2-like protein 1 isoform Bcl-X(S) (human)
hBCL2L1/iso:Bcl-X(S)
"A Bcl-2-like protein 1 isoform 2 that is encoded in the genome of human." [PRO:JAN]

organism-sequence


PR:Q64373-2
Bcl-2-like protein 1 isoform Bcl-X(S) (mouse)
mBCL2L1/iso:Bcl-X(S)
"A Bcl-2-like protein 1 isoform 2 that is encoded in the genome of mouse." [PRO:JAN]
Yes
sequence


PR:000002387
Bcl-2-like protein 1 isoform 3
BCL2L1/iso:3
"A Bcl-2-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07817-3 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q07817-3
Bcl-2-like protein 1 isoform Bcl-X(beta) (human)
hBCL2L1/iso:Bcl-X(beta)
"A Bcl-2-like protein 1 isoform 3 that is encoded in the genome of human." [PRO:JAN]

sequence


PR:000002388
Bcl-2-like protein 1 isoform 4
BCL2L1/iso:4
"A Bcl-2-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64373-3 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q64373-3
Bcl-2-like protein 1 isoform Bcl-X(beta) (mouse)
mBCL2L1/iso:Bcl-X(beta)
"A Bcl-2-like protein 1 isoform 4 that is encoded in the genome of mouse." [PRO:JAN]

sequence


PR:000002389
Bcl-2-like protein 1 isoform 5
BCL2L1/iso:5
"A Bcl-2-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64373-4 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q64373-4
Bcl-2-like protein 1 isoform Bcl-X(delta-TM) (mouse)
mBCL2L1/iso:Bcl-X(delta-TM)
"A Bcl-2-like protein 1 isoform 5 that is encoded in the genome of mouse." [PRO:JAN]

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q07817-1 hBCL2L1/iso:1 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:10949026
GO:0043066 negative regulation of apoptotic process PMID:8596636
enablesNOT GO:0005515 protein binding with PR:000028379 hBID/iso:1/Clv:1 PMID:10949026
NOT GO:0005515 protein binding with PR:O54918 Bcl2-interacting mediator of cell death (mouse) PMID:10949026
NOT GO:0005515 protein binding with PR:Q07812 BAX PMID:10949026
NOT GO:0005515 protein binding with PR:Q16611 apoptosis regulator BAK (human) PMID:10949026
NOT GO:0005515 protein binding with PR:Q61337 Bad PMID:10949026
NOT GO:0005515 protein binding with PR:Q92934-1 PMID:10949026
NOT GO:0005515 protein binding with PR:000026167 mBAD/iso:1/Phos:1 PMID:10949026
NOT GO:0005515 protein binding with PR:000026133 mBAD/iso:1/Phos:2 PMID:10949026
PR:Q64373-1 mBCL2L1/iso:Bcl-X(L) acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process MGI_ref:81233; PMID:8798158
GO:0043066 negative regulation of apoptotic process MGI_ref:81233; PMID:8798158
associated_with_disease_progressionDO:162 cancer PMID:16403219
enablesGO:0005515 protein binding with PR:O08734 apoptosis regulator BAK (mouse) MGI_ref:3804133; PMID:16705087
GO:0046982 protein heterodimerization activity MGI_ref:82784; PMID:8798452
PR:Q64373-2 mBCL2L1/iso:Bcl-X(S) acts_upstream_of_or_withinGO:0043065 positive regulation of apoptotic process MGI_ref:81233; PMID:8798158