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Protein Ontology report - Bcl2-associated agonist of cell death isoform 2
PR:000002281 - http://purl.obolibrary.org/obo/PR_000002281
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002281   
  PRO nameBcl2-associated agonist of cell death isoform 2 
  Synonyms
PRO-Short-label: EXACT:BAD/iso:2
  Definition"A Bcl2-associated agonist of cell death that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92934-1 or a 1:1 ortholog thereof." [PRO:JAN] 
  PRO Categorysequence 
  ParentPR:000002184 Bcl2-associated agonist of cell death
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification3                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000002281

Bcl2-associated agonist of cell death isoform 2

BAD/iso:2


"A Bcl2-associated agonist of cell death that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92934-1 or a 1:1 ortholog thereof." [PRO:JAN]


organism-sequence



PR:Q3U9H3

Bcl2-associated agonist of cell death isoform 2 (mouse)

mBAD/iso:2


"A Bcl2-associated agonist of cell death isoform 2 that is encoded in the genome of mouse." [PRO:JAN]


organism-sequence



PR:Q92934-1

Bcl2-associated agonist of cell death isoform 1 (human)

hBAD/iso:1


"A Bcl2-associated agonist of cell death isoform 2 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000026140

Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human)

hBAD/iso:2/Phos:1


"A Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 in human. UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046." [PMID:10195903, PMID:16932738, PRO:JAN]

Yes

organism-modification



PR:000044749

Bcl2-associated agonist of cell death isoform 2 unmodified form (human)

hBAD/iso:2/UnMod


"A Bcl2-associated agonist of cell death isoform 2 unmodified form in human." [PRO:DNx]

Yes

modification



PR:000002844

Bcl2-associated agonist of cell death isoform 2 unmodified form

BAD/iso:2/UnMod


"A Bcl2-associated agonist of cell death isoform 2 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]


organism-modification



PR:000044749

Bcl2-associated agonist of cell death isoform 2 unmodified form (human)

hBAD/iso:2/UnMod


"A Bcl2-associated agonist of cell death isoform 2 unmodified form in human." [PRO:DNx]

Yes

modification



PR:000003231

Bcl2-associated agonist of cell death isoform 2 phosphorylated form

BAD/iso:2/PhosRes+


"A Bcl2-associated agonist of cell death isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]


modification



PR:000003232

Bcl2-associated agonist of cell death isoform 2 phosphorylated 1

BAD/iso:2/Phos:1


"A Bcl2-associated agonist of cell death isoform 2 phosphorylated form in which the phosphorylation occurs on the indicated Ser residues within each of two RxRxxSxP motifs in the BH3 domain. The latter site is the major PKA phosphorylation site. Phosphorylation on these residues favors binding to 14-3-3 proteins. Example: UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046." [PRO:DAN, PRO:JAN]


organism-modification



PR:000026140

Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human)

hBAD/iso:2/Phos:1


"A Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 in human. UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046." [PMID:10195903, PMID:16932738, PRO:JAN]

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026140 hBAD/iso:2/Phos:1
UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046
enablesdecreased GO:0005515 protein binding with PR:Q07817-1 PMID:10195903
GO:0005829 cytosol PMID:10195903
GO:0019902 phosphatase binding PMID:10195903
GO:0071889 14-3-3 protein binding PMID:16932738
located_inGO:0005829 cytosol PMID:10195903
PR:000044749 hBAD/iso:2/UnMod enablesGO:0005515 protein binding with PR:Q07817-1 PMID:10195903
located_inGO:0005739 mitochondrion PMID:10195903