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 |
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family
|
|
PR:000002195 |
caspase-1-like protease
|
APAF1
|
"A protein that is a translation product of a family of genes that includes CASP1, CASP2, CASP4, CASP5, CASP9 and others. The core architecture consists of a Caspase recruitment domain (Pfam:PF00619), Caspase domain (Pfam:PF00656) and a PAAD/DAPIN/Pyrin domain (Pfam:PF02758). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis." [PRO:WCB]
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gene
|
|
PR:000002309 |
caspase-1
|
CASP1
|
"A caspase-1-like protease that is a translation product of the human CASP1 gene or a 1:1 ortholog thereof. The active form of this protein proteolytically cleaves pro-IL-1beta to its mature, active form. The holoenzyme is a homodimer of catalytic domains, each of which contains the cleaved products caspase-1 p20 and p10 subunits." [PMID:8044845, PRO:WCB]
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organism-gene
|
|
PR:P29452 |
caspase-1 (mouse)
|
mCASP1
|
"A caspase-1 that is encoded in the genome of mouse." [OMA:P29452, PRO:DNx]
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| |
organism-sequence
|
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PR:P29452-1 |
caspase-1 isoform 1 (mouse)
|
mCASP1/iso:1
|
"A caspase-1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
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| |
organism-modification
|
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PR:000078346 |
caspase-1 cysteinylated 1 (mouse)
|
mCASP1/Cyst:1
|
"A caspase-1 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-168 of the amino acid sequence represented by UniProtKB:P29452. UniProtKB:P29452, Cys-168, MOD:00765." [IEDB_epitope:2089306, PRO:DNx]
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organism-gene
|
|
PR:P29466 |
caspase-1 (human)
|
hCASP1
|
"A caspase-1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P29466]
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| |
organism-sequence
|
|
PR:P29466-1 |
caspase-1 isoform alpha (human)
|
hCASP1/iso:alpha
|
"A caspase-1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-2 |
caspase-1 isoform beta (human)
|
hCASP1/iso:beta
|
"A caspase-1 isoform 2 that is encoded in the genome of human." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-3 |
caspase-1 isoform gamma (human)
|
hCASP1/iso:gamma
|
"A caspase-1 isoform 3 that is encoded in the genome of human." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-4 |
caspase-1 isoform delta (human)
|
hCASP1/iso:delta
|
"A caspase-1 isoform 4 that is encoded in the genome of human." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-5 |
caspase-1 isoform epsilon (human)
|
hCASP1/iso:epsilon
|
"A caspase-1 isoform 5 that is encoded in the genome of human." [PRO:JAN]
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| |
organism-modification
|
|
PR:000079348 |
caspase-1 cysteinylated 1 (human)
|
hCASP1/Cyst:1
|
"A caspase-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-136 of the amino acid sequence represented by UniProtKB:P29466-1. Example: UniProtKB:P29466-1, Cys-136, MOD:00765." [IEDB_epitope:924947, PRO:DNx]
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organism-gene
|
|
PR:P43527 |
caspase-1 (rat)
|
rCASP1
|
"A caspase-1 that is encoded in the genome of rat." [OMA:P43527, PRO:DNx]
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| | | |
sequence
|
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PR:000002390 |
caspase-1 isoform 1
|
CASP1/iso:1
|
"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-1 or a 1:1 ortholog thereof." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29452-1 |
caspase-1 isoform 1 (mouse)
|
mCASP1/iso:1
|
"A caspase-1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
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| |
organism-sequence
|
|
PR:P29466-1 |
caspase-1 isoform alpha (human)
|
hCASP1/iso:alpha
|
"A caspase-1 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
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| | | | | | | | |
| |
modification
|
|
PR:000002449 |
caspase-1 isoform 1 cleaved 1
|
CASP1/iso:1/Clv:1
|
"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p20." [PMID:8044845, PRO:JAN]
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| |
modification
|
|
PR:000002450 |
caspase-1 isoform 1 cleaved 2
|
CASP1/iso:1/Clv:2
|
"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p10." [PMID:8044845, PRO:JAN]
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| | | |
sequence
|
|
PR:000002391 |
caspase-1 isoform 2
|
CASP1/iso:2
|
"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-2 or a 1:1 ortholog thereof." [PMID:15489334, PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-2 |
caspase-1 isoform beta (human)
|
hCASP1/iso:beta
|
"A caspase-1 isoform 2 that is encoded in the genome of human." [PRO:JAN]
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| | | |
sequence
|
|
PR:000002392 |
caspase-1 isoform 3
|
CASP1/iso:3
|
"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-3 or a 1:1 ortholog thereof." [PMID:15489334, PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-3 |
caspase-1 isoform gamma (human)
|
hCASP1/iso:gamma
|
"A caspase-1 isoform 3 that is encoded in the genome of human." [PRO:JAN]
|
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| | | | | | |
| | | |
sequence
|
|
PR:000002393 |
caspase-1 isoform 4
|
CASP1/iso:4
|
"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-4 or a 1:1 ortholog thereof." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-4 |
caspase-1 isoform delta (human)
|
hCASP1/iso:delta
|
"A caspase-1 isoform 4 that is encoded in the genome of human." [PRO:JAN]
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| | | |
sequence
|
|
PR:000002394 |
caspase-1 isoform 5
|
CASP1/iso:5
|
"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-5 or a 1:1 ortholog thereof." [PRO:JAN]
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| |
organism-sequence
|
|
PR:P29466-5 |
caspase-1 isoform epsilon (human)
|
hCASP1/iso:epsilon
|
"A caspase-1 isoform 5 that is encoded in the genome of human." [PRO:JAN]
|
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| | | | | | |
| | | |
sequence
|
|
PR:000002395 |
caspase-1 isoform 6
|
CASP1/iso:6
|
"A caspase-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P29466-1, 40-404 or a 1:1 ortholog thereof." [PMID:15498465, PRO:JAN]
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| | | |
modification
|
|
PR:000018758 |
caspase-1 proteolytic cleavage product
|
CASP1/ClvPrd
|
"A caspase-1 that has been processed by proteolytic cleavage." [PRO:DNx]
|
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| |
modification
|
|
PR:000002449 |
caspase-1 isoform 1 cleaved 1
|
CASP1/iso:1/Clv:1
|
"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p20." [PMID:8044845, PRO:JAN]
|
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| | | | | | | | |
| |
modification
|
|
PR:000002450 |
caspase-1 isoform 1 cleaved 2
|
CASP1/iso:1/Clv:2
|
"A caspase-1 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-1 subunit p10." [PMID:8044845, PRO:JAN]
|
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gene
|
|
PR:000002311 |
caspase-2
|
CASP2
|
"A caspase-1-like protease that is a translation product of the human CASP2 gene or a 1:1 ortholog thereof. This protein is involved in the activation cascade of caspases responsible for apoptosis execution." [PRO:WCB]
|
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| | | |
organism-gene
|
|
PR:P29594 |
caspase-2 (mouse)
|
mCASP2
|
"A caspase-2 that is encoded in the genome of mouse." [OMA:P29594, PRO:DNx]
|
|
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|
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|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:P29594-1 |
caspase-2 isoform 1 (mouse)
|
mCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
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| | | |
organism-gene
|
|
PR:P42575 |
caspase-2 (human)
|
hCASP2
|
"A caspase-2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P42575]
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:P42575-1 |
caspase-2 isoform 1 (human)
|
hCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
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|
| | | | | | | | | | |
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
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|
| | | | | | | | | | |
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
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|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:P42575-2 |
caspase-2 isoform 2 (human)
|
hCASP2/iso:2
|
"A caspase-2 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P42575-3 |
caspase-2 isoform h3 (human)
|
hCASP2/iso:h3
|
"A caspase-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-3." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000045782 |
caspase-2 phosphorylated 1 (human)
|
hCASP2/Phos:1
|
"A caspase-2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-157 of the amino acid sequence represented by UniProtKB:P42575-1. Example: UniProtKB:P42575-1, Ser-157, MOD:00046." [iPTMnet:P42575, PMID:16193064]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000046570 |
caspase-2, initiator methionine removed form (human)
|
hCASP2/InitMet-
|
"A caspase-2 (human) that has had the initiator methionine removed. UniProtKB:P42575, 2-452." [PRO:DNx, Reactome:R-HSA-622412]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000070230 |
caspase-2 methylated 1 (human)
|
hCASP2/Me:1
|
"A caspase-2 (human) that has been methylated on the residue at the position equivalent to Cys-436 of the amino acid sequence represented by UniProtKB:P42575-1. Example: UniProtKB:P42575-1, Cys-436, MOD:00660." [IEDB_epitope:1023721, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000080352 |
caspase-2 methylated 2 (human)
|
hCASP2/Me:2
|
"A caspase-2 (human) that has been methylated on the residue at the position equivalent to Cys-270 of the amino acid sequence represented by UniProtKB:P42575-1. Example: UniProtKB:P42575-1, Cys-270, MOD:00660." [IEDB_epitope:1059558, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P55215 |
caspase-2 (rat)
|
rCASP2
|
"A caspase-2 that is encoded in the genome of rat." [OMA:P55215, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55215-1 |
caspase-2 isoform r1 (rat)
|
rCASP2/iso:r1
|
"A caspase-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55215-1." [PRO:DNx, UniProtKB:P55215]
|
|
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|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55215-2 |
caspase-2 isoform r2 (rat)
|
rCASP2/iso:r2
|
"A caspase-2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55215-2." [PRO:DNx, UniProtKB:P55215]
|
|
|
|
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|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q98943 |
caspase-2 (chicken)
|
chick-CASP2
|
"A caspase-2 that is encoded in the genome of chicken." [OMA:Q98943, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q98943-1 |
caspase-2 isoform ICH-1L (chicken)
|
chick-CASP2/iso:ICH-1L
|
"A caspase-2 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q98943-1." [PRO:DNx, UniProtKB:Q98943]
|
|
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|
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|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q98943-2 |
caspase-2 isoform ICH-1S (chicken)
|
chick-CASP2/iso:ICH-1S
|
"A caspase-2 (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q98943-2." [PRO:DNx, UniProtKB:Q98943]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9XYF4 |
caspase Dronc (fruit fly)
|
fly-CASP2
|
"A caspase-2 that is encoded in the genome of fruit fly." [OMA:Q9XYF4, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002400 |
caspase-2 isoform 1
|
CASP2/iso:1
|
"A caspase-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-1 or a 1:1 ortholog thereof. This isoform acts as a positive regulator of apoptosis." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P29594-1 |
caspase-2 isoform 1 (mouse)
|
mCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P42575-1 |
caspase-2 isoform 1 (human)
|
hCASP2/iso:1
|
"A caspase-2 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002451 |
caspase-2 subunit p18
|
CASP2/p18
|
"A caspase-2 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P42575-1, 170-325." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002452 |
caspase-2 subunit p13
|
CASP2/p13
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. UniProtKB:P42575-1, 334-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002453 |
caspase-2 subunit p12
|
CASP2/p12
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides and a short intersubunit linker (in humans, the N-terminal-most 14 amino acids of the p13 form). UniProtKB:P42575-1, 348-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002401 |
caspase-2 isoform 2
|
CASP2/iso:2
|
"A caspase-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42575-2 or a 1:1 ortholog thereof. This isoform acts as a negative regulator of apoptosis." [PRO:JAN]
|
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:P42575-2 |
caspase-2 isoform 2 (human)
|
hCASP2/iso:2
|
"A caspase-2 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
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|
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| | | | | | |
| | | |
modification
|
|
PR:000018760 |
caspase-2, initiator methionine removed form
|
CASP2/InitMet-
|
"A caspase-2 that has had the initiator methionine removed." [PRO:DNx]
|
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| | | | | | | | |
| |
organism-modification
|
|
PR:000046570 |
caspase-2, initiator methionine removed form (human)
|
hCASP2/InitMet-
|
"A caspase-2 (human) that has had the initiator methionine removed. UniProtKB:P42575, 2-452." [PRO:DNx, Reactome:R-HSA-622412]
|
|
|
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|
|
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| | | | | | |
| | | |
modification
|
|
PR:000018761 |
caspase-2 proteolytic cleavage product
|
CASP2/ClvPrd
|
"A caspase-2 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
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|
| | | | | | | | |
| |
modification
|
|
PR:000002451 |
caspase-2 subunit p18
|
CASP2/p18
|
"A caspase-2 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P42575-1, 170-325." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
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|
| | | | | | | | | | |
organism-modification
|
|
PR:000050110 |
caspase-2 subunit p18 (human)
|
hCASP2/p18
|
"A caspase-2 subunit p18 in human. Example: UniProtKB:P42575-1, 170-325." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002452 |
caspase-2 subunit p13
|
CASP2/p13
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. UniProtKB:P42575-1, 334-452." [PMID:8654923, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050111 |
caspase-2 subunit p13 (human)
|
hCASP2/p13
|
"A caspase-2 subunit p13 in human. Example: UniProtKB:P42575-1, 334-452." [PRO:DNx, UniProtKB:P42575]
|
|
|
|
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| | | | | | | | |
| |
modification
|
|
PR:000002453 |
caspase-2 subunit p12
|
CASP2/p12
|
"A caspase-2 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides and a short intersubunit linker (in humans, the N-terminal-most 14 amino acids of the p13 form). UniProtKB:P42575-1, 348-452." [PMID:8654923, PRO:DAN, PRO:JAN]
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| | | | | | | | | | |
organism-modification
|
|
PR:000050112 |
caspase-2 subunit p12 (human)
|
hCASP2/p12
|
"A caspase-2 subunit p12 in human. Example: UniProtKB:P42575-1, 348-452." [PRO:DAN, UniProtKB:P42575]
|
|
|
|
|
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| | | | |
| | | | | |
gene
|
|
PR:000002313 |
caspase-4
|
CASP4
|
"A caspase-1-like protease that is a translation product of the human CASP4 gene or a 1:1 ortholog thereof." [PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P49662 |
caspase-4 (human)
|
hCASP4
|
"A caspase-4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P49662]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P49662-1 |
caspase-4 isoform 1 (human)
|
hCASP4/iso:1
|
"A caspase-4 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P49662-2 |
caspase-4 isoform h2 (human)
|
hCASP4/iso:h2
|
"A caspase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49662-2." [PRO:DNx, UniProtKB:P49662]
|
|
|
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:P49662-3 |
caspase-4 isoform h3 (human)
|
hCASP4/iso:h3
|
"A caspase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49662-3." [PRO:DNx, UniProtKB:P49662]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P49662-4 |
caspase-4 isoform h4 (human)
|
hCASP4/iso:h4
|
"A caspase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49662-4." [PRO:DNx, UniProtKB:P49662]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P49662-5 |
caspase-4 isoform h5 (human)
|
hCASP4/iso:h5
|
"A caspase-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49662-5." [PRO:DNx, UniProtKB:P49662]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000065529 |
caspase-4 methylated 1 (human)
|
hCASP4/Me:1
|
"A caspase-4 (human) that has been methylated on the residue at the position equivalent to Cys-109 of the amino acid sequence represented by UniProtKB:P49662-1. Example: UniProtKB:P49662-1, Cys-109, MOD:00660." [IEDB_epitope:1024634, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P70343 |
caspase-4 (mouse)
|
mCASP4
|
"A caspase-4 that is encoded in the genome of mouse." [OMA:P70343, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P70343-1 |
caspase-4 isoform 1 (mouse)
|
mCASP4/iso:1
|
"A caspase-4 isoform 2 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P70343-2 |
caspase-4 isoform m2 (mouse)
|
mCASP4/iso:m2
|
"A caspase-4 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70343-2." [PRO:DNx, UniProtKB:P70343]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002403 |
caspase-4 isoform 1
|
CASP4/iso:1
|
"A caspase-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49662-1 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P49662-1 |
caspase-4 isoform 1 (human)
|
hCASP4/iso:1
|
"A caspase-4 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002404 |
caspase-4 isoform 2
|
CASP4/iso:2
|
"A caspase-4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70343-1 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P70343-1 |
caspase-4 isoform 1 (mouse)
|
mCASP4/iso:1
|
"A caspase-4 isoform 2 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000018763 |
caspase-4 proteolytic cleavage product
|
CASP4/ClvPrd
|
"A caspase-4 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000002314 |
caspase-5
|
CASP5
|
"A caspase-1-like protease that is a translation product of the human CASP5 gene or a 1:1 ortholog thereof." [PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P51878 |
caspase-5 (human)
|
hCASP5
|
"A caspase-5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P51878]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-1 |
caspase-5 isoform 1 (human)
|
hCASP5/iso:1
|
"A caspase-5 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-2 |
caspase-5 isoform h2 (human)
|
hCASP5/iso:h2
|
"A caspase-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51878-2." [PRO:DNx, UniProtKB:P51878]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-3 |
caspase-5 isoform h3 (human)
|
hCASP5/iso:h3
|
"A caspase-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51878-3." [PRO:DNx, UniProtKB:P51878]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-4 |
caspase-5 isoform h4 (human)
|
hCASP5/iso:h4
|
"A caspase-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51878-4." [PRO:DNx, UniProtKB:P51878]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-5 |
caspase-5 isoform h5 (human)
|
hCASP5/iso:h5
|
"A caspase-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51878-5." [PRO:DNx, UniProtKB:P51878]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-6 |
caspase-5 isoform h6 (human)
|
hCASP5/iso:h6
|
"A caspase-5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51878-6." [PRO:DNx, UniProtKB:P51878]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000070225 |
caspase-5 cysteinylated 1 (human)
|
hCASP5/Cyst:1
|
"A caspase-5 (human) that has been cysteinylated on the residue at the position equivalent to Cys-361 of the amino acid sequence represented by UniProtKB:P51878-1. Example: UniProtKB:P51878-1, Cys-361, MOD:00765." [IEDB_epitope:924956, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002405 |
caspase-5 isoform 1
|
CASP5/iso:1
|
"A caspase-5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51878-1 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P51878-1 |
caspase-5 isoform 1 (human)
|
hCASP5/iso:1
|
"A caspase-5 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000018764 |
caspase-5 proteolytic cleavage product
|
CASP5/ClvPrd
|
"A caspase-5 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | |
| | | | | |
gene
|
|
PR:000002318 |
caspase-9
|
CASP9
|
"A caspase-1-like protease that is a translation product of the human CASP9 gene or a 1:1 ortholog thereof." [PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:F1NL59 |
caspase (chicken)
|
chick-CASP9
|
"A caspase-9 that is encoded in the genome of chicken." [OMA:F1NL59, PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:P55211 |
caspase-9 (human)
|
hCASP9
|
"A caspase-9 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P55211]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55211-1 |
caspase-9 isoform 1 (human)
|
hCASP9/iso:1
|
"A caspase-9 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55211-2 |
caspase-9 isoform 2 (human)
|
hCASP9/iso:2
|
"A caspase-9 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55211-3 |
caspase-9 isoform h3 (human)
|
hCASP9/iso:h3
|
"A caspase-9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55211-3." [PRO:DNx, UniProtKB:P55211]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55211-4 |
caspase-9 isoform h4 (human)
|
hCASP9/iso:h4
|
"A caspase-9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55211-4." [PRO:DNx, UniProtKB:P55211]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000045839 |
caspase-9 phosphorylated 1 (human)
|
hCASP9/Phos:1
|
"A caspase-9 (human) that has been phosphorylated on the residue at the position equivalent to Thr-125 of the amino acid sequence represented by UniProtKB:P55211-1. Example: UniProtKB:P55211-1, Thr-125, MOD:00047." [iPTMnet:P55211, PMID:12792650, PMID:17466630]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000046571 |
caspase-9 phosphorylated 2 (human)
|
hCASP9/Phos:2
|
"A caspase-9 (human) that has been phosphorylated on the residue at the position equivalent to Ser-196 of the amino acid sequence represented by UniProtKB:P55211. UniProtKB:P55211, Ser-196, MOD:00046." [PRO:DNx, Reactome:R-HSA-198636]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050095 |
caspase-9 subunit p35 (human)
|
hCASP9/p35
|
"A caspase-9 subunit p35 in human. Example: UniProtKB:P55211-1, ?-315." [PRO:DNx, UniProtKB:P55211]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000050096 |
caspase-9 subunit p10 (human)
|
hCASP9/p10
|
"A caspase-9 subunit p10 in human. Example: UniProtKB:P55211-1, 331-416." [PRO:DNx, UniProtKB:P55211]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q8C3Q9 |
caspase-9 (mouse)
|
mCASP9
|
"A caspase-9 that is encoded in the genome of mouse." [OMA:Q8C3Q9, PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9JHK1 |
caspase (rat)
|
rCASP9
|
"A caspase-9 that is encoded in the genome of rat." [OMA:Q9JHK1, PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002421 |
caspase-9 isoform 1
|
CASP9/iso:1
|
"A caspase-9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55211-1 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55211-1 |
caspase-9 isoform 1 (human)
|
hCASP9/iso:1
|
"A caspase-9 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002460 |
caspase-9 isoform 1 subunit p35
|
CASP9/iso:1/p35
|
"A caspase-9 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P55211-1, ?-315." [PMID:8900201, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002461 |
caspase-9 isoform 1 subunit p10
|
CASP9/iso:1/p10
|
"A caspase-9 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. Example: UniProtKB:P55211-1, 331-416." [PMID:8900201, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002422 |
caspase-9 isoform 2
|
CASP9/iso:2
|
"A caspase-9 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P55211-2 or a 1:1 ortholog thereof." [PMID:9890966, PRO:DAN, PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:P55211-2 |
caspase-9 isoform 2 (human)
|
hCASP9/iso:2
|
"A caspase-9 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
modification
|
|
PR:000018769 |
caspase-9 proteolytic cleavage product
|
CASP9/ClvPrd
|
"A caspase-9 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002460 |
caspase-9 isoform 1 subunit p35
|
CASP9/iso:1/p35
|
"A caspase-9 isoform 1 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P55211-1, ?-315." [PMID:8900201, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000002461 |
caspase-9 isoform 1 subunit p10
|
CASP9/iso:1/p10
|
"A caspase-9 isoform 1 that corresponds to the C-terminal portion after removal of the propeptides. Example: UniProtKB:P55211-1, 331-416." [PMID:8900201, PRO:CNA, PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000050089 |
caspase-9 subunit p35
|
CASP9/p35
|
"A caspase-9 that corresponds to the N-terminal portion after removal of the propeptides. Example: UniProtKB:P55211-1, ?-315." [PRO:DAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000050095 |
caspase-9 subunit p35 (human)
|
hCASP9/p35
|
"A caspase-9 subunit p35 in human. Example: UniProtKB:P55211-1, ?-315." [PRO:DNx, UniProtKB:P55211]
|
|
|
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000050090 |
caspase-9 subunit p10
|
CASP9/p10
|
"A caspase-9 that corresponds to the C-terminal portion after removal of the propeptides. Example: UniProtKB:P55211-1, 331-416." [PRO:DAN]
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organism-modification
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PR:000050096 |
caspase-9 subunit p10 (human)
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hCASP9/p10
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"A caspase-9 subunit p10 in human. Example: UniProtKB:P55211-1, 331-416." [PRO:DNx, UniProtKB:P55211]
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