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Protein Ontology report - caspase-1-like protease

PR:000002195 - http://purl.obolibrary.org/obo/PR_000002195

Protein Forms

Ontology Information

Show OBO stanza

PRO ID

PR:000002195

PRO name

caspase-1-like protease

Definition

"A protein that is a translation product of a family of genes that includes CASP1, CASP2, CASP4, CASP5, CASP9 and others. The core architecture consists of a Caspase recruitment domain (Pfam:PF00619), Caspase domain (Pfam:PF00656) and a PAAD/DAPIN/Pyrin domain (Pfam:PF02758). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis." [PRO:WCB]

PRO Category

family

Parent

PR:000000001 protein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Family	1	Organism-Family	0
Gene	5	Organism-Gene	15
Sequence	13	Organism-Sequence	31
Modification	15	Organism-Modification	15

Term Hierarchy
Visualization

DAG:

OLS:

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Related Cross References
Db identifiers	PIRSF:PIRSF038001

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

family

PR:000002195 caspase-1-like protease

APAF1

gene

PR:000002309 caspase-1

CASP1

organism-gene

PR:P29452 caspase-1 (mouse)

mCASP1

organism-sequence

PR:P29452-1 caspase-1 isoform 1 (mouse)

mCASP1/iso:1

organism-modification

PR:000078346 caspase-1 cysteinylated 1 (mouse)

mCASP1/Cyst:1

organism-gene

PR:P29466 caspase-1 (human)

hCASP1

organism-sequence

PR:P29466-1 caspase-1 isoform alpha (human)

hCASP1/iso:alpha

organism-sequence

PR:P29466-2 caspase-1 isoform beta (human)

hCASP1/iso:beta

organism-sequence

PR:P29466-3 caspase-1 isoform gamma (human)

hCASP1/iso:gamma

organism-sequence

PR:P29466-4 caspase-1 isoform delta (human)

hCASP1/iso:delta

organism-sequence

PR:P29466-5 caspase-1 isoform epsilon (human)

hCASP1/iso:epsilon

organism-modification

PR:000079348 caspase-1 cysteinylated 1 (human)

hCASP1/Cyst:1

organism-gene

PR:P43527 caspase-1 (rat)

rCASP1

sequence

PR:000002390 caspase-1 isoform 1

CASP1/iso:1

organism-sequence

PR:P29452-1 caspase-1 isoform 1 (mouse)

mCASP1/iso:1

organism-sequence

PR:P29466-1 caspase-1 isoform alpha (human)

hCASP1/iso:alpha

modification

PR:000002449 caspase-1 isoform 1 cleaved 1

CASP1/iso:1/Clv:1

modification

PR:000002450 caspase-1 isoform 1 cleaved 2

CASP1/iso:1/Clv:2

sequence

PR:000002391 caspase-1 isoform 2

CASP1/iso:2

organism-sequence

PR:P29466-2 caspase-1 isoform beta (human)

hCASP1/iso:beta

sequence

PR:000002392 caspase-1 isoform 3

CASP1/iso:3

organism-sequence

PR:P29466-3 caspase-1 isoform gamma (human)

hCASP1/iso:gamma

sequence

PR:000002393 caspase-1 isoform 4

CASP1/iso:4

organism-sequence

PR:P29466-4 caspase-1 isoform delta (human)

hCASP1/iso:delta

sequence

PR:000002394 caspase-1 isoform 5

CASP1/iso:5

organism-sequence

PR:P29466-5 caspase-1 isoform epsilon (human)

hCASP1/iso:epsilon

sequence

PR:000002395 caspase-1 isoform 6

CASP1/iso:6

modification

PR:000018758 caspase-1 proteolytic cleavage product

CASP1/ClvPrd

modification

PR:000002449 caspase-1 isoform 1 cleaved 1

CASP1/iso:1/Clv:1

modification

PR:000002450 caspase-1 isoform 1 cleaved 2

CASP1/iso:1/Clv:2

gene

PR:000002311 caspase-2

CASP2

organism-gene

PR:P29594 caspase-2 (mouse)

mCASP2

organism-sequence

PR:P29594-1 caspase-2 isoform 1 (mouse)

mCASP2/iso:1

organism-gene

PR:P42575 caspase-2 (human)

hCASP2

organism-sequence

PR:P42575-1 caspase-2 isoform 1 (human)

hCASP2/iso:1

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

organism-sequence

PR:P42575-2 caspase-2 isoform 2 (human)

hCASP2/iso:2

organism-sequence

PR:P42575-3 caspase-2 isoform h3 (human)

hCASP2/iso:h3

organism-modification

PR:000045782 caspase-2 phosphorylated 1 (human)

hCASP2/Phos:1

organism-modification

PR:000046570 caspase-2, initiator methionine removed form (human)

hCASP2/InitMet-

organism-modification

PR:000070230 caspase-2 methylated 1 (human)

hCASP2/Me:1

organism-modification

PR:000080352 caspase-2 methylated 2 (human)

hCASP2/Me:2

organism-gene

PR:P55215 caspase-2 (rat)

rCASP2

organism-sequence

PR:P55215-1 caspase-2 isoform r1 (rat)

rCASP2/iso:r1

organism-sequence

PR:P55215-2 caspase-2 isoform r2 (rat)

rCASP2/iso:r2

organism-gene

PR:Q98943 caspase-2 (chicken)

chick-CASP2

organism-sequence

PR:Q98943-1 caspase-2 isoform ICH-1L (chicken)

chick-CASP2/iso:ICH-1L

organism-sequence

PR:Q98943-2 caspase-2 isoform ICH-1S (chicken)

chick-CASP2/iso:ICH-1S

organism-gene

PR:Q9XYF4 caspase Dronc (fruit fly)

fly-CASP2

sequence

PR:000002400 caspase-2 isoform 1

CASP2/iso:1

organism-sequence

PR:P29594-1 caspase-2 isoform 1 (mouse)

mCASP2/iso:1

organism-sequence

PR:P42575-1 caspase-2 isoform 1 (human)

hCASP2/iso:1

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

modification

PR:000002451 caspase-2 subunit p18

CASP2/p18

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

modification

PR:000002452 caspase-2 subunit p13

CASP2/p13

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

modification

PR:000002453 caspase-2 subunit p12

CASP2/p12

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

sequence

PR:000002401 caspase-2 isoform 2

CASP2/iso:2

organism-sequence

PR:P42575-2 caspase-2 isoform 2 (human)

hCASP2/iso:2

modification

PR:000018760 caspase-2, initiator methionine removed form

CASP2/InitMet-

organism-modification

PR:000046570 caspase-2, initiator methionine removed form (human)

hCASP2/InitMet-

modification

PR:000018761 caspase-2 proteolytic cleavage product

CASP2/ClvPrd

modification

PR:000002451 caspase-2 subunit p18

CASP2/p18

organism-modification

PR:000050110 caspase-2 subunit p18 (human)

hCASP2/p18

modification

PR:000002452 caspase-2 subunit p13

CASP2/p13

organism-modification

PR:000050111 caspase-2 subunit p13 (human)

hCASP2/p13

modification

PR:000002453 caspase-2 subunit p12

CASP2/p12

organism-modification

PR:000050112 caspase-2 subunit p12 (human)

hCASP2/p12

gene

PR:000002313 caspase-4

CASP4

organism-gene

PR:P49662 caspase-4 (human)

hCASP4

organism-sequence

PR:P49662-1 caspase-4 isoform 1 (human)

hCASP4/iso:1

organism-sequence

PR:P49662-2 caspase-4 isoform h2 (human)

hCASP4/iso:h2

organism-sequence

PR:P49662-3 caspase-4 isoform h3 (human)

hCASP4/iso:h3

organism-sequence

PR:P49662-4 caspase-4 isoform h4 (human)

hCASP4/iso:h4

organism-sequence

PR:P49662-5 caspase-4 isoform h5 (human)

hCASP4/iso:h5

organism-modification

PR:000065529 caspase-4 methylated 1 (human)

hCASP4/Me:1

organism-gene

PR:P70343 caspase-4 (mouse)

mCASP4

organism-sequence

PR:P70343-1 caspase-4 isoform 1 (mouse)

mCASP4/iso:1

organism-sequence

PR:P70343-2 caspase-4 isoform m2 (mouse)

mCASP4/iso:m2

sequence

PR:000002403 caspase-4 isoform 1

CASP4/iso:1

organism-sequence

PR:P49662-1 caspase-4 isoform 1 (human)

hCASP4/iso:1

sequence

PR:000002404 caspase-4 isoform 2

CASP4/iso:2

organism-sequence

PR:P70343-1 caspase-4 isoform 1 (mouse)

mCASP4/iso:1

modification

PR:000018763 caspase-4 proteolytic cleavage product

CASP4/ClvPrd

gene

PR:000002314 caspase-5

CASP5

organism-gene

PR:P51878 caspase-5 (human)

hCASP5

organism-sequence

PR:P51878-1 caspase-5 isoform 1 (human)

hCASP5/iso:1

organism-sequence

PR:P51878-2 caspase-5 isoform h2 (human)

hCASP5/iso:h2

organism-sequence

PR:P51878-3 caspase-5 isoform h3 (human)

hCASP5/iso:h3

organism-sequence

PR:P51878-4 caspase-5 isoform h4 (human)

hCASP5/iso:h4

organism-sequence

PR:P51878-5 caspase-5 isoform h5 (human)

hCASP5/iso:h5

organism-sequence

PR:P51878-6 caspase-5 isoform h6 (human)

hCASP5/iso:h6

organism-modification

PR:000070225 caspase-5 cysteinylated 1 (human)

hCASP5/Cyst:1

sequence

PR:000002405 caspase-5 isoform 1

CASP5/iso:1

organism-sequence

PR:P51878-1 caspase-5 isoform 1 (human)

hCASP5/iso:1

modification

PR:000018764 caspase-5 proteolytic cleavage product

CASP5/ClvPrd

gene

PR:000002318 caspase-9

CASP9

organism-gene

PR:F1NL59 caspase (chicken)

chick-CASP9

organism-gene

PR:P55211 caspase-9 (human)

hCASP9

organism-sequence

PR:P55211-1 caspase-9 isoform 1 (human)

hCASP9/iso:1

organism-sequence

PR:P55211-2 caspase-9 isoform 2 (human)

hCASP9/iso:2

organism-sequence

PR:P55211-3 caspase-9 isoform h3 (human)

hCASP9/iso:h3

organism-sequence

PR:P55211-4 caspase-9 isoform h4 (human)

hCASP9/iso:h4

organism-modification

PR:000045839 caspase-9 phosphorylated 1 (human)

hCASP9/Phos:1

organism-modification

PR:000046571 caspase-9 phosphorylated 2 (human)

hCASP9/Phos:2

organism-modification

PR:000050095 caspase-9 subunit p35 (human)

hCASP9/p35

organism-modification

PR:000050096 caspase-9 subunit p10 (human)

hCASP9/p10

organism-gene

PR:Q8C3Q9 caspase-9 (mouse)

mCASP9

organism-gene

PR:Q9JHK1 caspase (rat)

rCASP9

sequence

PR:000002421 caspase-9 isoform 1

CASP9/iso:1

organism-sequence

PR:P55211-1 caspase-9 isoform 1 (human)

hCASP9/iso:1

modification

PR:000002460 caspase-9 isoform 1 subunit p35

CASP9/iso:1/p35

modification

PR:000002461 caspase-9 isoform 1 subunit p10

CASP9/iso:1/p10

sequence

PR:000002422 caspase-9 isoform 2

CASP9/iso:2

organism-sequence

PR:P55211-2 caspase-9 isoform 2 (human)

hCASP9/iso:2

modification

PR:000018769 caspase-9 proteolytic cleavage product

CASP9/ClvPrd

modification

PR:000002460 caspase-9 isoform 1 subunit p35

CASP9/iso:1/p35

modification

PR:000002461 caspase-9 isoform 1 subunit p10

CASP9/iso:1/p10

modification

PR:000050089 caspase-9 subunit p35

CASP9/p35

organism-modification

PR:000050095 caspase-9 subunit p35 (human)

hCASP9/p35

modification

PR:000050090 caspase-9 subunit p10

CASP9/p10

organism-modification

PR:000050096 caspase-9 subunit p10 (human)

hCASP9/p10