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gene
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 PR:000002193 |
   apoptosis regulator BAX
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   BAX
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  "A protein that is a translation product of the human BAX gene or a 1:1 ortholog thereof. In this class the Bcl-2 domain is characterized by the presence of the BH3, BH1, and BH2 motifs." [PRO:SY, PRO:WCB]
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organism-gene
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 PR:Q07812 |
   apoptosis regulator BAX (human)
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   hBAX
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  "An apoptosis regulator BAX that is encoded in the genome of human." [PRO:SY, UniProtKB:Q07812]
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organism-sequence
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 PR:Q07812-1 |
   apoptosis regulator BAX isoform alpha (human)
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   hBAX/iso:alpha
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  "An apoptosis regulator BAX isoform 1 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-2 |
   apoptosis regulator BAX isoform beta (human)
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   hBAX/iso:beta
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  "An apoptosis regulator BAX isoform 2 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-3 |
   apoptosis regulator BAX isoform gamma (human)
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   hBAX/iso:gamma
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  "An apoptosis regulator BAX isoform 3 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-4 |
   apoptosis regulator BAX isoform delta (human)
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   hBAX/iso:delta
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  "An apoptosis regulator BAX isoform 4 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-5 |
   apoptosis regulator BAX isoform epsilon (human)
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   hBAX/iso:epsilon
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  "An apoptosis regulator BAX isoform 5 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-6 |
   apoptosis regulator BAX isoform zeta (human)
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   hBAX/iso:zeta
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  "An apoptosis regulator BAX isoform 6 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-7 |
   apoptosis regulator BAX isoform psi (human)
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   hBAX/iso:psi
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  "An apoptosis regulator BAX isoform 7 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-8 |
   apoptosis regulator BAX isoform sigma (human)
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   hBAX/iso:sigma
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  "An apoptosis regulator BAX isoform 8 that is encoded in the genome of human." [PRO:SY]
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organism-modification
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 PR:000036214 |
   apoptosis regulator BAX acetylated 1 (human)
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   hBAX/Ac:1
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  "An apoptosis regulator BAX (human) that is N-terminal Met acetylated. Example: UniProtKB:Q07812-1, Met-1, MOD:00058." [TDR:1457]
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organism-modification
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 PR:000045886 |
   apoptosis regulator BAX phosphorylated 1 (human)
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   hBAX/Phos:1
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  "An apoptosis regulator BAX (human) that has been phosphorylated on the residue at the position equivalent to Thr-167 of the amino acid sequence represented by UniProtKB:Q07812-1. Example: UniProtKB:Q07812-1, Thr-167, MOD:00047." [iPTMnet:Q07812, PMID:19182807]
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organism-modification
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 PR:000081293 |
   apoptosis regulator BAX methylated 1 (human)
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   hBAX/Me:1
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  "An apoptosis regulator BAX (human) that has been methylated on the residue at the position equivalent to Cys-126 of the amino acid sequence represented by UniProtKB:Q07812-1. Example: UniProtKB:Q07812-1, Cys-126, MOD:00660." [IEDB_epitope:1000223, PRO:DNx]
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organism-gene
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 PR:Q07813 |
   apoptosis regulator BAX (mouse)
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   mBAX
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  "An apoptosis regulator BAX that is encoded in the genome of mouse." [OMA:Q07813, PRO:SY, PRO:WCB]
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organism-sequence
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 PR:Q07813-1 |
   apoptosis regulator BAX isoform Alpha (mouse)
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   mBAX/iso:Alpha
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  "An apoptosis regulator BAX isoform 1 that is encoded in the genome of mouse." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07813-2 |
   apoptosis regulator BAX isoform Beta (mouse)
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   mBAX/iso:Beta
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  "An apoptosis regulator BAX (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07813-2." [PRO:DNx, UniProtKB:Q07813]
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organism-sequence
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 PR:Q07813-3 |
   apoptosis regulator BAX isoform Gamma (mouse)
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   mBAX/iso:Gamma
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  "An apoptosis regulator BAX (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07813-3." [PRO:DNx, UniProtKB:Q07813]
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organism-sequence
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 PR:Q8K3J2 |
   Bcl2-associated X protein kappa isoform (mouse)
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   mBAX/iso:7
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  "An apoptosis regulator BAX isoform 7 that is encoded in the genome of mouse." [PRO:JAN, PRO:SY]
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organism-modification
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 PR:000036213 |
   apoptosis regulator BAX acetylated 1 (mouse)
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   mBAX/Ac:1
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  "An apoptosis regulator BAX (mouse) that is N-terminal Met acetylated. Example: UniProtKB:Q07813-1, Met-1, MOD:00058." [TDR:9284]
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organism-gene
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 PR:Q63690 |
   apoptosis regulator BAX (rat)
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   rBAX
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  "An apoptosis regulator BAX that is encoded in the genome of rat." [OMA:Q63690, PRO:DNx]
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organism-sequence
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 PR:Q63690-1 |
   apoptosis regulator BAX isoform Alpha (rat)
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   rBAX/iso:Alpha
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  "An apoptosis regulator BAX (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63690-1." [PRO:DNx, UniProtKB:Q63690]
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organism-sequence
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 PR:Q63690-2 |
   apoptosis regulator BAX isoform Beta (rat)
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   rBAX/iso:Beta
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  "An apoptosis regulator BAX (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63690-2." [PRO:DNx, UniProtKB:Q63690]
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organism-sequence
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 PR:Q63690-3 |
   apoptosis regulator BAX isoform Gamma (rat)
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   rBAX/iso:Gamma
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  "An apoptosis regulator BAX (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q63690-3." [PRO:DNx, UniProtKB:Q63690]
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sequence
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 PR:000002299 |
   apoptosis regulator BAX isoform 1
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   BAX/iso:1
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-1 or a 1:1 ortholog thereof. It contains one copy of the Bcl-2 domain, and a C-terminal single transmembrane domain." [PMID:8358790, PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-1 |
   apoptosis regulator BAX isoform alpha (human)
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   hBAX/iso:alpha
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  "An apoptosis regulator BAX isoform 1 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07813-1 |
   apoptosis regulator BAX isoform Alpha (mouse)
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   mBAX/iso:Alpha
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  "An apoptosis regulator BAX isoform 1 that is encoded in the genome of mouse." [PRO:JAN, PRO:SY]
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modification
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 PR:000003267 |
   apoptosis regulator BAX isoform 1 phosphorylated form
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   BAX/iso:1/PhosRes+
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  "An apoptosis regulator BAX isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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 PR:000003268 |
   apoptosis regulator BAX isoform 1 phosphorylated 1
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   BAX/iso:1/Phos:1
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  "An apoptosis regulator BAX isoform 1 phosphorylated form in which the phosphorylation occurs at a Ser residue upon AKT activation. Example: UniProtKB:Q07813-1, Ser-184, MOD:00046." [PMID:14766748, PRO:JAN]
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sequence
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 PR:000002300 |
   apoptosis regulator BAX isoform 2
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   BAX/iso:2
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-2 or a 1:1 ortholog thereof. It lacks the transmembrane domain due to the presence of a longer and distinct C-terminal sequence compared to isoform 1." [PMID:8358790, PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-2 |
   apoptosis regulator BAX isoform beta (human)
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   hBAX/iso:beta
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  "An apoptosis regulator BAX isoform 2 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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sequence
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 PR:000002301 |
   apoptosis regulator BAX isoform 3
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   BAX/iso:3
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-3 or a 1:1 ortholog thereof. Isoform 3 is about 40 residues long comprising the first 11 N-terminal residues in common to isoform 1 and a unique C-terminal sequence." [PMID:8358790, PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-3 |
   apoptosis regulator BAX isoform gamma (human)
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   hBAX/iso:gamma
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  "An apoptosis regulator BAX isoform 3 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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sequence
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 PR:000002302 |
   apoptosis regulator BAX isoform 4
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   BAX/iso:4
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-4 or a 1:1 ortholog thereof. Isoform 4 has in common with isoform 1 the N-terminal (first 30 residues) and C-terminal regions, but differs from isoform 1 in that the former lacks a region of about 50 residues, that includes the BH3 motif region, therefore isoform 4 contains a partial copy of the Bcl-2 domain." [PMID:7607685, PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-4 |
   apoptosis regulator BAX isoform delta (human)
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   hBAX/iso:delta
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  "An apoptosis regulator BAX isoform 4 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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sequence
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 PR:000002303 |
   apoptosis regulator BAX isoform 5
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   BAX/iso:5
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-5 or a 1:1 ortholog thereof. Isoform 5 differs from isoform 1 in that the former lacks the BH2 motif region, because it contains a different C-terminal sequence." [PMID:9920818, PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-5 |
   apoptosis regulator BAX isoform epsilon (human)
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   hBAX/iso:epsilon
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  "An apoptosis regulator BAX isoform 5 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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sequence
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 PR:000002304 |
   apoptosis regulator BAX isoform 6
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   BAX/iso:6
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-6 or a 1:1 ortholog thereof. It lacks the N-terminal region up to the end of the BH3 motif. Isoform 6 contains a partial copy of the Bcl-2 domain." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-6 |
   apoptosis regulator BAX isoform zeta (human)
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   hBAX/iso:zeta
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  "An apoptosis regulator BAX isoform 6 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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sequence
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 PR:000002305 |
   apoptosis regulator BAX isoform 7
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   BAX/iso:7
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-7 or a 1:1 ortholog thereof. Isoform 7 is missing the N-terminal region of about 20 residues compared to isoform 1." [PMID:11912183, PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q07812-7 |
   apoptosis regulator BAX isoform psi (human)
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   hBAX/iso:psi
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  "An apoptosis regulator BAX isoform 7 that is encoded in the genome of human." [PRO:JAN, PRO:SY]
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organism-sequence
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 PR:Q8K3J2 |
   Bcl2-associated X protein kappa isoform (mouse)
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   mBAX/iso:7
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  "An apoptosis regulator BAX isoform 7 that is encoded in the genome of mouse." [PRO:JAN, PRO:SY]
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sequence
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 PR:000002306 |
   apoptosis regulator BAX isoform 8
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   BAX/iso:8
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  "An apoptosis regulator BAX that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q07812-8 or a 1:1 ortholog thereof. Isoform 8 differs from isoform 1 in that the former lacks the region between the BH2 motif region and the transmembrane domain." [PMID:10200554, PRO:SY]
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organism-sequence
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 PR:Q07812-8 |
   apoptosis regulator BAX isoform sigma (human)
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   hBAX/iso:sigma
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  "An apoptosis regulator BAX isoform 8 that is encoded in the genome of human." [PRO:SY]
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