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Protein Ontology report - tyrosine-protein kinase ITK/TSK
PR:000002111 - http://purl.obolibrary.org/obo/PR_000002111
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000002111   
  PRO nametyrosine-protein kinase ITK/TSK 
  Synonyms
PRO-Short-label: EXACT:ITK
Gene-based: RELATED:EMT | LYK | Tlk | Tsk
Other: EXACT:IL-2-inducible T-cell kinase | kinase EMT | kinase TLK | T-cell-specific kinase | tyrosine-protein kinase Lyk
  Definition"A TEC-type tyrosine-protein kinase that is a translation product of the human ITK gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001967 TEC-type tyrosine-protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence2                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500766;IUPHARobj:2046
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002111
tyrosine-protein kinase ITK/TSK
ITK
"A TEC-type tyrosine-protein kinase that is a translation product of the human ITK gene or a 1:1 ortholog thereof." [PRO:WCB]

organism-gene


PR:P08630
tyrosine-protein kinase Btk (fruit fly)
fly-ITK
"A tyrosine-protein kinase ITK/TSK that is encoded in the genome of fruit fly." [OMA:P08630, PRO:DNx]

organism-sequence


PR:P08630-1
tyrosine-protein kinase Btk isoform B (fruit fly)
fly-ITK/iso:B
"A tyrosine-protein kinase Btk (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08630-1." [PRO:DNx, UniProtKB:P08630]

organism-sequence


PR:P08630-2
tyrosine-protein kinase Btk isoform A (fruit fly)
fly-ITK/iso:A
"A tyrosine-protein kinase Btk (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08630-2." [PRO:DNx, UniProtKB:P08630]

organism-gene


PR:Q03526
tyrosine-protein kinase ITK/TSK (mouse)
mITK
"A tyrosine-protein kinase ITK/TSK that is encoded in the genome of mouse." [OMA:Q03526, PRO:DNx]

organism-sequence


PR:Q03526-1
tyrosine-protein kinase ITK/TSK isoform 1 (mouse)
mITK/iso:1
"A tyrosine-protein kinase ITK/TSK isoform 1 that is encoded in the genome of mouse." [PRO:JAN]

organism-sequence


PR:Q5STT8
tyrosine-protein kinase ITK/TSK isoform 2 (mouse)
mITK/iso:2
"A tyrosine-protein kinase ITK/TSK isoform 2 that is encoded in the genome of mouse." [PRO:JAN]

organism-gene


PR:Q08881
tyrosine-protein kinase ITK/TSK (human)
hITK
"A tyrosine-protein kinase ITK/TSK that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q08881]

organism-sequence


PR:Q08881-1
tyrosine-protein kinase ITK/TSK isoform 1 (human)
hITK/iso:1
"A tyrosine-protein kinase ITK/TSK isoform 2 that is encoded in the genome of human." [PRO:JAN]

organism-modification


PR:000048074
tyrosine-protein kinase ITK/TSK phosphorylated 1 (human)
hITK/Phos:1
"A tyrosine-protein kinase ITK/TSK (human) that has been post-translationally modified to include phosphotyrosine at positions 180 and 512 of the amino acid sequence represented by UniProtKB:Q08881. UniProtKB:Q08881, Tyr-180/Tyr-512, MOD:00048." [PRO:DNx, Reactome:R-HSA-2685616]

organism-modification


PR:000048075
tyrosine-protein kinase ITK/TSK phosphorylated 2 (human)
hITK/Phos:2
"A tyrosine-protein kinase ITK/TSK (human) that has been phosphorylated on the residue at the position equivalent to Tyr-512 of the amino acid sequence represented by UniProtKB:Q08881. UniProtKB:Q08881, Tyr-512, MOD:00048." [PMID:9312162, PRO:DNx, Reactome:R-HSA-422519]

organism-modification


PR:000068201
tyrosine-protein kinase ITK/TSK cysteinylated 1 (human)
hITK/Cyst:1
"A tyrosine-protein kinase ITK/TSK (human) that has been cysteinylated on the residue at the position equivalent to Cys-432 of the amino acid sequence represented by UniProtKB:Q08881. UniProtKB:Q08881, Cys-432, MOD:00765." [IEDB_epitope:1568633, PRO:DNx]

organism-modification


PR:000069845
tyrosine-protein kinase ITK/TSK cysteinylated 2 (human)
hITK/Cyst:2
"A tyrosine-protein kinase ITK/TSK (human) that has been cysteinylated on the residue at the position equivalent to Cys-594 of the amino acid sequence represented by UniProtKB:Q08881. UniProtKB:Q08881, Cys-594, MOD:00765." [IEDB_epitope:932736, PRO:DNx]

organism-gene


PR:Q19726
non-specific protein-tyrosine kinase (worm)
ITK (worm)
"A tyrosine-protein kinase ITK/TSK that is encoded in the genome of worm." [PRO:WCB]

sequence


PR:000002238
tyrosine-protein kinase ITK/TSK isoform 1
ITK/iso:1
"A tyrosine-protein kinase ITK/TSK that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03526-1 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q03526-1
tyrosine-protein kinase ITK/TSK isoform 1 (mouse)
mITK/iso:1
"A tyrosine-protein kinase ITK/TSK isoform 1 that is encoded in the genome of mouse." [PRO:JAN]

sequence


PR:000002239
tyrosine-protein kinase ITK/TSK isoform 2
ITK/iso:2
"A tyrosine-protein kinase ITK/TSK that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08881-1 or a 1:1 ortholog thereof." [PRO:JAN]

organism-sequence


PR:Q08881-1
tyrosine-protein kinase ITK/TSK isoform 1 (human)
hITK/iso:1
"A tyrosine-protein kinase ITK/TSK isoform 2 that is encoded in the genome of human." [PRO:JAN]

organism-sequence


PR:Q5STT8
tyrosine-protein kinase ITK/TSK isoform 2 (mouse)
mITK/iso:2
"A tyrosine-protein kinase ITK/TSK isoform 2 that is encoded in the genome of mouse." [PRO:JAN]