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Protein Ontology report - tyrosine-protein kinase BTK
PR:000002110 - http://purl.obolibrary.org/obo/PR_000002110
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002110   
  PRO nametyrosine-protein kinase BTK 
  Synonyms
PRO-Short-label: EXACT:BTK
Gene-based: RELATED:AGMX1 | ATK | BPK
Other: EXACT:agammaglobulinaemia tyrosine kinase | agammaglobulinemia tyrosine kinase | B-cell progenitor kinase | bruton tyrosine kinase | kinase EMB
  Definition"A TEC-type tyrosine-protein kinase that is a translation product of the human BTK gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001967 TEC-type tyrosine-protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification2                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF500765;IUPHARobj:1948
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002110 tyrosine-protein kinase BTK
BTK

organism-gene


PR:P35991 tyrosine-protein kinase BTK (mouse)
mBTK

Yes
organism-sequence


PR:P35991-1 tyrosine-protein kinase BTK isoform 1 (mouse)
mBTK/iso:1

organism-modification


PR:000037482 tyrosine-protein kinase BTK phosphorylated 1 (mouse)
mBTK/Phos:1

organism-gene


PR:Q06187 tyrosine-protein kinase BTK (human)
hBTK

organism-sequence


PR:Q06187-1 tyrosine-protein kinase BTK isoform BTK-A (human)
hBTK/iso:BTK-A

organism-sequence


PR:Q06187-2 tyrosine-protein kinase BTK isoform BTK-C (human)
hBTK/iso:BTK-C

organism-modification


PR:000044351 tyrosine-protein kinase BTK, initiator methionine removed form (human)
hBTK/InitMet-

Yes
organism-modification


PR:000046518 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 2 (human)
hBTK/InitMet-/Phos:2

organism-modification


PR:000046519 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 1 (human)
hBTK/InitMet-/Phos:1

organism-modification


PR:000045882 tyrosine-protein kinase BTK phosphorylated 1 (human)
hBTK/Phos:1

organism-modification


PR:000069637 tyrosine-protein kinase BTK deaminated 1 (human)
hBTK/Deam:1

organism-modification


PR:000070839 tyrosine-protein kinase BTK deaminated 2 (human)
hBTK/Deam:2

organism-modification


PR:000077962 tyrosine-protein kinase BTK methylated 1 (human)
hBTK/Me:1

sequence


PR:000002236 tyrosine-protein kinase BTK isoform 1
BTK/iso:1

organism-sequence


PR:P35991-1 tyrosine-protein kinase BTK isoform 1 (mouse)
mBTK/iso:1

organism-sequence


PR:Q06187-1 tyrosine-protein kinase BTK isoform BTK-A (human)
hBTK/iso:BTK-A

modification


PR:000026589 tyrosine-protein kinase BTK isoform 1, initiator methionine removed form
BTK/iso:1/InitMet-

modification


PR:000018724 tyrosine-protein kinase BTK, initiator methionine removed form
BTK/InitMet-

modification


PR:000026589 tyrosine-protein kinase BTK isoform 1, initiator methionine removed form
BTK/iso:1/InitMet-

organism-modification


PR:000044351 tyrosine-protein kinase BTK, initiator methionine removed form (human)
hBTK/InitMet-

Yes
organism-modification


PR:000046518 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 2 (human)
hBTK/InitMet-/Phos:2

organism-modification


PR:000046519 tyrosine-protein kinase BTK, initiator methionine removed phosphorylated 1 (human)
hBTK/InitMet-/Phos:1

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BTK forms found in complexes   

BTK Component
 Complexes
PR:000044351 hBTK/InitMet- PR:000037446 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037447 TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037448 pTIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:P35991 mBTK PR:000037477 TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037478 pTIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse)