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Protein Ontology report - integrin beta-3
PR:000002042 - http://purl.obolibrary.org/obo/PR_000002042
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000002042   
  PRO nameintegrin beta-3 
  Synonyms
PRO-Short-label: EXACT:ITGB3
Gene-based: RELATED:GP3A
Other: EXACT:CD61 | GPIIIa | platelet membrane glycoprotein IIIa
  Definition"An integrin beta that is a translation product of the human ITGB3 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001861 integrin beta
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2457
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000002042

integrin beta-3

ITGB3


"An integrin beta that is a translation product of the human ITGB3 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:O54890

integrin beta-3 (mouse)

mITGB3


"An integrin beta-3 that is encoded in the genome of mouse." [PRO:WCB]


organism-gene



PR:P05106

integrin beta-3 (human)

hITGB3


"An integrin beta-3 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P05106-1

integrin beta-3 isoform hBeta-3A (human)

hITGB3/iso:hBeta-3A


"An integrin beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05106-1." [PRO:DNx, UniProtKB:P05106]


organism-sequence



PR:P05106-2

integrin beta-3 isoform hBeta-3B (human)

hITGB3/iso:hBeta-3B


"An integrin beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05106-2." [PRO:DNx, UniProtKB:P05106]


organism-sequence



PR:P05106-3

integrin beta-3 isoform hBeta-3C (human)

hITGB3/iso:hBeta-3C


"An integrin beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05106-3." [PRO:DNx, UniProtKB:P05106]


organism-modification



PR:000041631

integrin beta-3, signal peptide removed form (human)

hITGB3/SigPep-


"An integrin beta-3 (human) that has the signal peptide removed. Example: UniProtKB:P05106-1, 27-788." [PRO:DAN]


Yes
organism-modification



PR:000048069

integrin beta-3, signal peptide removed phosphorylated 1 (human)

hITGB3/SigPep-/Phos:1


"An integrin beta-3, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Thr-779 of the amino acid sequence represented by UniProtKB:P05106. UniProtKB:P05106, 27-788, Thr-779, MOD:00047." [PRO:DNx, Reactome:R-HSA-432107]


organism-modification



PR:000053450

integrin beta-3 N-glycosylated 1 (human)

hITGB3/NGlyco:1


"An integrin beta-3 (human) that has been N-glycosylated at the residue equivalent to Asn-125 of the amino acid sequence represented by UniProtKB:P05106-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P05106-1, Asn-125, MOD:00160~GNO:G00912UN." [GlyGen:P05106-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000053451

integrin beta-3 N-glycosylated 2 (human)

hITGB3/NGlyco:2


"An integrin beta-3 (human) that has been N-glycosylated at the residue equivalent to Asn-125 of the amino acid sequence represented by UniProtKB:P05106-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P05106-1, Asn-125, MOD:00160~GNO:G59626AS." [GlyGen:P05106-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000076948

integrin beta-3 cysteinylated 1 (human)

hITGB3/Cyst:1


"An integrin beta-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-75 of the amino acid sequence represented by UniProtKB:P05106-1. Example: UniProtKB:P05106-1, Cys-75, MOD:00765." [IEDB_epitope:1581339, PRO:DNx]


organism-gene



PR:Q8R2H2

integrin beta-3 (rat)

rITGB3


"An integrin beta-3 that is encoded in the genome of rat." [PRO:WCB]


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ITGB3 forms found in complexes   

ITGB3 Component
Complexes
PR:000041631 hITGB3/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)