back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - beta-type platelet-derived growth factor receptor
PR:000002035 - http://purl.obolibrary.org/obo/PR_000002035
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002035   
  PRO namebeta-type platelet-derived growth factor receptor 
  Synonyms
PRO-Short-label: EXACT:PDGFRB
Gene-based: RELATED:PDGFR1
Other: EXACT:beta platelet-derived growth factor receptor | CD140 antigen-like family member B | CD140b | PDGF-R-beta | PDGFR-1 | PDGFR-beta | platelet-derived growth factor receptor 1
RELATED:Pdgfr
  Definition"A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human PDGFRB gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence2                                                  Organism-Sequence 4                                        
         Modification4                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF500948;IUPHARobj:1804
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002035 beta-type platelet-derived growth factor receptor
PDGFRB

organism-gene


PR:P05622 platelet-derived growth factor receptor beta (mouse)
mPDGFRB

organism-sequence


PR:P05622-1 platelet-derived growth factor receptor beta isoform 1 (mouse)
mPDGFRB/iso:1

organism-sequence


PR:P05622-2 platelet-derived growth factor receptor beta isoform m2 (mouse)
mPDGFRB/iso:m2

organism-gene


PR:P09619 platelet-derived growth factor receptor beta (human)
hPDGFRB

organism-sequence


PR:P09619-1 platelet-derived growth factor receptor beta isoform 1 (human)
hPDGFRB/iso:1

organism-sequence


PR:P09619-2 platelet-derived growth factor receptor beta isoform h2 (human)
hPDGFRB/iso:h2

organism-modification


PR:000048725 platelet-derived growth factor receptor beta, signal peptide removed form (human)
hPDGFRB/SigPep-

organism-modification


PR:000048726 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 1 (human)
hPDGFRB/SigPep-/Phos:1

organism-modification


PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
hPDGFRB/SigPep-/Phos:2
Yes
organism-modification


PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human)
hPDGFRB/SigPep-/Phos:3
Yes
organism-modification


PR:000049848 platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human)
hPDGFRB/SigPep-/UnPhos:2
Yes
organism-modification


PR:000064602 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 4 (human)
hPDGFRB/SigPep-/Phos:4

organism-gene


PR:Q05030 platelet-derived growth factor receptor beta (rat)
rPDGFRB

sequence


PR:000002136 beta-type platelet-derived growth factor receptor isoform 1
PDGFRB/iso:1

organism-sequence


PR:P05622-1 platelet-derived growth factor receptor beta isoform 1 (mouse)
mPDGFRB/iso:1

modification


PR:000026683 beta-type platelet-derived growth factor receptor isoform 1, signal peptide removed form
PDGFRB/iso:1/SigPep-

sequence


PR:000002137 beta-type platelet-derived growth factor receptor isoform 2
PDGFRB/iso:2

organism-sequence


PR:P09619-1 platelet-derived growth factor receptor beta isoform 1 (human)
hPDGFRB/iso:1

modification


PR:000002143 beta-type platelet-derived growth factor receptor isoform 2, signal peptide removed form
PDGFRB/iso:2/SigPep-

modification


PR:000018702 beta-type platelet-derived growth factor receptor, signal peptide removed form
PDGFRB/SigPep-

modification


PR:000002143 beta-type platelet-derived growth factor receptor isoform 2, signal peptide removed form
PDGFRB/iso:2/SigPep-

modification


PR:000026683 beta-type platelet-derived growth factor receptor isoform 1, signal peptide removed form
PDGFRB/iso:1/SigPep-

organism-modification


PR:000048725 platelet-derived growth factor receptor beta, signal peptide removed form (human)
hPDGFRB/SigPep-

organism-modification


PR:000048726 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 1 (human)
hPDGFRB/SigPep-/Phos:1

organism-modification


PR:000049846 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 2 (human)
hPDGFRB/SigPep-/Phos:2
Yes
organism-modification


PR:000049847 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human)
hPDGFRB/SigPep-/Phos:3
Yes
organism-modification


PR:000049848 platelet-derived growth factor receptor beta, signal peptide removed unphosphorylated 2 (human)
hPDGFRB/SigPep-/UnPhos:2
Yes
organism-modification


PR:000064602 platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 4 (human)
hPDGFRB/SigPep-/Phos:4

modification


PR:000025415 beta-type platelet-derived growth factor receptor proteolytic cleavage product
PDGFRB/ClvPrd

Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
increased GO:0018108 peptidyl-tyrosine phosphorylationPR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:1653029; PMID:9642269
GO:0038083 peptidyl-tyrosine autophosphorylationPR:000049848 hPDGFRB/SigPep-/UnPhos:2 PMID:9642269
decreased GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transductionPR:000049847 hPDGFRB/SigPep-/Phos:3 PMID:15271984

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0004713 protein tyrosine kinase activityPR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15994317; PMID:9642269
PR:000049847 hPDGFRB/SigPep-/Phos:3 PMID:15271984
GO:0005515 protein bindingPR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:1653029
PR:000049847 hPDGFRB/SigPep-/Phos:3 PMID:15271984