back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - integrin beta
PR:000001861 - http://purl.obolibrary.org/obo/PR_000001861
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001861   
  PRO nameintegrin beta 
  Definition"A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725)." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene8                                                  Organism-Gene 20                                        
         Sequence7                                                  Organism-Sequence 23                                        
         Modification4                                                  Organism-Modification 47                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF002512
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001861

integrin beta

ICOS


"A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725)." [PRO:WCB]


gene



PR:000002040

integrin beta-1

ITGB1


"An integrin beta that is a translation product of the human ITGB1 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P05556

integrin beta-1 (human)

hITGB1


"An integrin beta-1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P05556]


organism-sequence



PR:P05556-1

integrin beta-1 isoform beta-1A (human)

hITGB1/iso:beta-1A


"An integrin beta-1 isoform beta-1A that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P05556-2

integrin beta-1 isoform beta-1B (human)

hITGB1/iso:beta-1B


"An integrin beta-1 isoform beta-1B that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P05556-3

integrin beta-1 isoform beta-1C (human)

hITGB1/iso:beta-1C


"An integrin beta-1 isoform beta-1C that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P05556-4

integrin beta-1 isoform beta-1C-2 (human)

hITGB1/iso:beta-1C-2


"An integrin beta-1 isoform beta-1C-2 that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P05556-5

integrin beta-1 isoform beta-1D (human)

hITGB1/iso:beta-1D


"An integrin beta-1 isoform beta-1D that is encoded in the genome of human." [PRO:CNA, UniProtKB:P05556]


organism-modification



PR:000028415

integrin beta-1, signal peptide removed form (human)

hITGB1/SigPep-


"An integrin beta-1, signal peptide removed form in human. Example: UniProtKB:P05556-1, 21-798." [PRO:DNx]


Yes
organism-modification



PR:000053565

integrin beta-1 N-glycosylated 1 (human)

hITGB1/NGlyco:1


"An integrin beta-1 (human) that has been N-glycosylated at the residue equivalent to Asn-212 of the amino acid sequence represented by UniProtKB:P05556-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P05556-1, Asn-212, MOD:00160~GNO:G25079LO." [GlyGen:P05556-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000053566

integrin beta-1 N-glycosylated 2 (human)

hITGB1/NGlyco:2


"An integrin beta-1 (human) that has been N-glycosylated at the residue equivalent to Asn-212 of the amino acid sequence represented by UniProtKB:P05556-1, in which the glycan composition is represented by GlyTouCan:G43769HG. Example: UniProtKB:P05556-1, Asn-212, MOD:00160~GNO:G43769HG." [GlyGen:P05556-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000053567

integrin beta-1 N-glycosylated 3 (human)

hITGB1/NGlyco:3


"An integrin beta-1 (human) that has been N-glycosylated at the residue equivalent to Asn-669 of the amino acid sequence represented by UniProtKB:P05556-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P05556-1, Asn-669, MOD:00160~GNO:G25079LO." [GlyGen:P05556-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000053568

integrin beta-1 N-glycosylated 4 (human)

hITGB1/NGlyco:4


"An integrin beta-1 (human) that has been N-glycosylated at the residue equivalent to Asn-97 of the amino acid sequence represented by UniProtKB:P05556-1, in which the glycan composition is represented by GlyTouCan:G25987BV. Example: UniProtKB:P05556-1, Asn-97, MOD:00160~GNO:G25987BV." [GlyGen:P05556-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000066244

integrin beta-1 deaminated 1 (human)

hITGB1/Deam:1


"An integrin beta-1 (human) that has been deaminated on the residue at the position equivalent to Asn-386 of the amino acid sequence represented by UniProtKB:P05556-1. Example: UniProtKB:P05556-1, Asn-386, MOD:00684." [IEDB_epitope:1994650, PRO:DNx]


organism-modification



PR:000066932

integrin beta-1 methylated 1 (human)

hITGB1/Me:1


"An integrin beta-1 (human) that has been methylated on the residue at the position equivalent to Cys-301 of the amino acid sequence represented by UniProtKB:P05556-1. Example: UniProtKB:P05556-1, Cys-301, MOD:00660." [IEDB_epitope:1016149, PRO:DNx]


organism-modification



PR:000070391

integrin beta-1 cysteinylated 1 (human)

hITGB1/Cyst:1


"An integrin beta-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-261 of the amino acid sequence represented by UniProtKB:P05556-1. Example: UniProtKB:P05556-1, Cys-261, MOD:00765." [IEDB_epitope:1331071, PRO:DNx]


organism-modification



PR:000072780

integrin beta-1 cysteinylated 2 (human)

hITGB1/Cyst:2


"An integrin beta-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-435 of the amino acid sequence represented by UniProtKB:P05556-1. Example: UniProtKB:P05556-1, Cys-435, MOD:00765." [IEDB_epitope:2120158, IEDB_epitope:2122640, IEDB_epitope:2122641, IEDB_epitope:2130035, PRO:DNx]


organism-modification



PR:000075713

integrin beta-1 cysteinylated 3 (human)

hITGB1/Cyst:3


"An integrin beta-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-415 of the amino acid sequence represented by UniProtKB:P05556-1. Example: UniProtKB:P05556-1, Cys-415, MOD:00765." [IEDB_epitope:2121254, PRO:DNx]


organism-modification



PR:000083387

integrin beta-1 cysteinylated 4 (human)

hITGB1/Cyst:4


"An integrin beta-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-207 of the amino acid sequence represented by UniProtKB:P05556-1. Example: UniProtKB:P05556-1, Cys-207, MOD:00765." [IEDB_epitope:2126186, PRO:DNx]


organism-gene



PR:P09055

integrin beta-1 (mouse)

mITGB1


"An integrin beta-1 that is encoded in the genome of mouse." [OMA:P09055, PRO:DNx]


organism-sequence



PR:P09055-1

integrin beta-1 isoform beta-1A (mouse)

mITGB1/iso:beta-1A


"An integrin beta-1 isoform beta-1A that is encoded in the genome of mouse." [PMID:8870969, PMID:9553049, PRO:KRC]

Yes

organism-sequence



PR:P09055-2

integrin beta-1 isoform beta-1D (mouse)

mITGB1/iso:beta-1D


"An integrin beta-1 isoform beta-1D that is encoded in the genome of mouse. This isoform contains a unique alternatively spliced cytoplasmic domain of 50 amino acids, with the last 24 amino acids encoded by an additional exon, 11 of these are in common with the isoform beta-1A." [PMID:8567725, PMID:8870969, PMID:9553049, PRO:KRC]

Yes

organism-gene



PR:P11584

integrin beta-PS (fruit fly)

fly-ITGB1


"An integrin beta-1 that is encoded in the genome of fruit fly." [OMA:P11584, PRO:DNx]


organism-gene



PR:P49134

integrin beta-1 (rat)

rITGB1


"An integrin beta-1 that is encoded in the genome of rat." [OMA:P49134, PRO:DNx]


organism-gene



PR:Q27874

integrin beta pat-3 (worm)

ITGB1 (worm)


"An integrin beta-1 that is encoded in the genome of worm." [OMA:Q27874, PRO:WCB]


sequence



PR:000037153

integrin beta-1 isoform beta-1A

ITGB1/iso:beta-1A


"An integrin beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05556-1 or a 1:1 ortholog thereof." [PRO:CNA, UniProtKB:P05556]


organism-sequence



PR:P05556-1

integrin beta-1 isoform beta-1A (human)

hITGB1/iso:beta-1A


"An integrin beta-1 isoform beta-1A that is encoded in the genome of human." [PRO:CNA]


organism-sequence



PR:P09055-1

integrin beta-1 isoform beta-1A (mouse)

mITGB1/iso:beta-1A


"An integrin beta-1 isoform beta-1A that is encoded in the genome of mouse." [PMID:8870969, PMID:9553049, PRO:KRC]

Yes

sequence



PR:000037155

integrin beta-1 isoform beta-1B

ITGB1/iso:beta-1B


"An integrin beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05556-2 or a 1:1 ortholog thereof." [PRO:CNA, UniProtKB:P05556]


organism-sequence



PR:P05556-2

integrin beta-1 isoform beta-1B (human)

hITGB1/iso:beta-1B


"An integrin beta-1 isoform beta-1B that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000037157

integrin beta-1 isoform beta-1C

ITGB1/iso:beta-1C


"An integrin beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05556-3 or a 1:1 ortholog thereof." [PRO:CNA, UniProtKB:P05556]


organism-sequence



PR:P05556-3

integrin beta-1 isoform beta-1C (human)

hITGB1/iso:beta-1C


"An integrin beta-1 isoform beta-1C that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000037159

integrin beta-1 isoform beta-1C-2

ITGB1/iso:beta-1C-2


"An integrin beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05556-4 or a 1:1 ortholog thereof." [PRO:CNA, UniProtKB:P05556]


organism-sequence



PR:P05556-4

integrin beta-1 isoform beta-1C-2 (human)

hITGB1/iso:beta-1C-2


"An integrin beta-1 isoform beta-1C-2 that is encoded in the genome of human." [PRO:CNA]


sequence



PR:000037161

integrin beta-1 isoform beta-1D

ITGB1/iso:beta-1D


"An integrin beta-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05556-5 or a 1:1 ortholog thereof." [PRO:CNA, UniProtKB:P05556]


organism-sequence



PR:P05556-5

integrin beta-1 isoform beta-1D (human)

hITGB1/iso:beta-1D


"An integrin beta-1 isoform beta-1D that is encoded in the genome of human." [PRO:CNA, UniProtKB:P05556]


organism-sequence



PR:P09055-2

integrin beta-1 isoform beta-1D (mouse)

mITGB1/iso:beta-1D


"An integrin beta-1 isoform beta-1D that is encoded in the genome of mouse. This isoform contains a unique alternatively spliced cytoplasmic domain of 50 amino acids, with the last 24 amino acids encoded by an additional exon, 11 of these are in common with the isoform beta-1A." [PMID:8567725, PMID:8870969, PMID:9553049, PRO:KRC]

Yes

modification



PR:000018706

integrin beta-1, signal peptide removed form

ITGB1/SigPep-


"An integrin beta-1 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000028415

integrin beta-1, signal peptide removed form (human)

hITGB1/SigPep-


"An integrin beta-1, signal peptide removed form in human. Example: UniProtKB:P05556-1, 21-798." [PRO:DNx]


Yes
gene



PR:000002041

integrin beta-2

ITGB2


"An integrin beta that is a translation product of the human ITGB2 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P05107

integrin beta-2 (human)

hITGB2


"An integrin beta-2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P05107]


organism-modification



PR:000027392

integrin beta-2, signal peptide removed form (human)

hITGB2/SigPep-


"An integrin beta-2, signal peptide removed form in human. UniProtKB:P05107, 23-769." [PRO:DNx]


Yes
organism-modification



PR:000045640

integrin beta-2 phosphorylated 1 (human)

hITGB2/Phos:1


"An integrin beta-2 (human) that has been phosphorylated at Tyr-735. UniProtKB:P05107, Tyr-735, MOD:00048." [iPTMnet:P05107, PMID:22990843]


organism-modification



PR:000065133

integrin beta-2 deaminated 1 (human)

hITGB2/Deam:1


"An integrin beta-2 (human) that has been deaminated on the residue at the position equivalent to Gln-101 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Gln-101, MOD:00685." [IEDB_epitope:778238, PRO:DNx]


organism-modification



PR:000067365

integrin beta-2 methylated 1 (human)

hITGB2/Me:1


"An integrin beta-2 (human) that has been methylated on the residue at the position equivalent to Cys-647 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-647, MOD:00660." [IEDB_epitope:1047261, PRO:DNx]


organism-modification



PR:000067820

integrin beta-2 methylated 2 (human)

hITGB2/Me:2


"An integrin beta-2 (human) that has been methylated on the residue at the position equivalent to Cys-695 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-695, MOD:00660." [IEDB_epitope:1040724, IEDB_epitope:1040725, IEDB_epitope:1062780, PRO:DNx]


organism-modification



PR:000068275

integrin beta-2 cysteinylated 1 (human)

hITGB2/Cyst:1


"An integrin beta-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-695 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-695, MOD:00765." [IEDB_epitope:885790, PRO:DNx]


organism-modification



PR:000068460

integrin beta-2 methylated 3 (human)

hITGB2/Me:3


"An integrin beta-2 (human) that has been methylated on the residue at the position equivalent to Cys-386 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-386, MOD:00660." [IEDB_epitope:1006140, PRO:DNx]


organism-modification



PR:000068638

integrin beta-2 deaminated 2 (human)

hITGB2/Deam:2


"An integrin beta-2 (human) that has been deaminated on the residue at the position equivalent to Asn-116 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Asn-116, MOD:00684." [IEDB_epitope:1593875, PRO:DNx]


organism-modification



PR:000069019

integrin beta-2 methylated 4 (human)

hITGB2/Me:4


"An integrin beta-2 (human) that has been methylated on the residue at the position equivalent to Cys-286 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-286, MOD:00660." [IEDB_epitope:1055053, PRO:DNx]


organism-modification



PR:000072514

integrin beta-2 cysteinylated 2 (human)

hITGB2/Cyst:2


"An integrin beta-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-286 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-286, MOD:00765." [IEDB_epitope:1859035, IEDB_epitope:2117920, IEDB_epitope:2118331, IEDB_epitope:2121234, IEDB_epitope:2126704, IEDB_epitope:2126705, IEDB_epitope:884732, PRO:DNx]


organism-modification



PR:000075467

integrin beta-2 methylated 5 (human)

hITGB2/Me:5


"An integrin beta-2 (human) that has been methylated on the residue at the position equivalent to Cys-198 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-198, MOD:00660." [IEDB_epitope:1007385, PRO:DNx]


organism-modification



PR:000083963

integrin beta-2 cysteinylated 3 (human)

hITGB2/Cyst:3


"An integrin beta-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-386 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-386, MOD:00765." [IEDB_epitope:876423, PRO:DNx]


organism-modification



PR:000084585

integrin beta-2 deaminated 3 (human)

hITGB2/Deam:3


"An integrin beta-2 (human) that has been deaminated on the residue at the position equivalent to Gln-317 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Gln-317, MOD:00685." [IEDB_epitope:770094, PRO:DNx]


organism-modification



PR:000085443

integrin beta-2 cysteinylated 4 (human)

hITGB2/Cyst:4


"An integrin beta-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-647 of the amino acid sequence represented by UniProtKB:P05107. UniProtKB:P05107, Cys-647, MOD:00765." [IEDB_epitope:1047260, PRO:DNx]


organism-gene



PR:P11835

integrin beta-2 (mouse)

mITGB2


"An integrin beta-2 that is encoded in the genome of mouse." [OMA:P11835, PRO:DNx]


modification



PR:000018708

integrin beta-2, signal peptide removed form

ITGB2/SigPep-


"An integrin beta-2 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000027392

integrin beta-2, signal peptide removed form (human)

hITGB2/SigPep-


"An integrin beta-2, signal peptide removed form in human. UniProtKB:P05107, 23-769." [PRO:DNx]


Yes
gene



PR:000002042

integrin beta-3

ITGB3


"An integrin beta that is a translation product of the human ITGB3 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:O54890

integrin beta-3 (mouse)

mITGB3


"An integrin beta-3 that is encoded in the genome of mouse." [PRO:WCB]


organism-gene



PR:P05106

integrin beta-3 (human)

hITGB3


"An integrin beta-3 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P05106-1

integrin beta-3 isoform hBeta-3A (human)

hITGB3/iso:hBeta-3A


"An integrin beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05106-1." [PRO:DNx, UniProtKB:P05106]


organism-sequence



PR:P05106-2

integrin beta-3 isoform hBeta-3B (human)

hITGB3/iso:hBeta-3B


"An integrin beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05106-2." [PRO:DNx, UniProtKB:P05106]


organism-sequence



PR:P05106-3

integrin beta-3 isoform hBeta-3C (human)

hITGB3/iso:hBeta-3C


"An integrin beta-3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05106-3." [PRO:DNx, UniProtKB:P05106]


organism-modification



PR:000041631

integrin beta-3, signal peptide removed form (human)

hITGB3/SigPep-


"An integrin beta-3 (human) that has the signal peptide removed. Example: UniProtKB:P05106-1, 27-788." [PRO:DAN]


Yes
organism-modification



PR:000048069

integrin beta-3, signal peptide removed phosphorylated 1 (human)

hITGB3/SigPep-/Phos:1


"An integrin beta-3, signal peptide removed form (human) that has been phosphorylated on the residue at the position equivalent to Thr-779 of the amino acid sequence represented by UniProtKB:P05106. UniProtKB:P05106, 27-788, Thr-779, MOD:00047." [PRO:DNx, Reactome:R-HSA-432107]


organism-modification



PR:000053450

integrin beta-3 N-glycosylated 1 (human)

hITGB3/NGlyco:1


"An integrin beta-3 (human) that has been N-glycosylated at the residue equivalent to Asn-125 of the amino acid sequence represented by UniProtKB:P05106-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P05106-1, Asn-125, MOD:00160~GNO:G00912UN." [GlyGen:P05106-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000053451

integrin beta-3 N-glycosylated 2 (human)

hITGB3/NGlyco:2


"An integrin beta-3 (human) that has been N-glycosylated at the residue equivalent to Asn-125 of the amino acid sequence represented by UniProtKB:P05106-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P05106-1, Asn-125, MOD:00160~GNO:G59626AS." [GlyGen:P05106-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000076948

integrin beta-3 cysteinylated 1 (human)

hITGB3/Cyst:1


"An integrin beta-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-75 of the amino acid sequence represented by UniProtKB:P05106-1. Example: UniProtKB:P05106-1, Cys-75, MOD:00765." [IEDB_epitope:1581339, PRO:DNx]


organism-gene



PR:Q8R2H2

integrin beta-3 (rat)

rITGB3


"An integrin beta-3 that is encoded in the genome of rat." [PRO:WCB]


gene



PR:000009141

integrin beta-5

ITGB5


"An integrin beta that is a translation product of the human ITGB5 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O70309

integrin beta-5 (mouse)

mITGB5


"An integrin beta-5 that is encoded in the genome of mouse." [OMA:O70309, PRO:DNx]


organism-sequence



PR:O70309-1

integrin beta-5 isoform mBeta-5A (mouse)

mITGB5/iso:mBeta-5A


"An integrin beta-5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70309-1." [PRO:DNx, UniProtKB:O70309]


organism-sequence



PR:O70309-2

integrin beta-5 isoform mBeta-5B (mouse)

mITGB5/iso:mBeta-5B


"An integrin beta-5 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O70309-2." [PRO:DNx, UniProtKB:O70309]


organism-modification



PR:000074127

integrin beta-5 cysteinylated 1 (mouse)

mITGB5/Cyst:1


"An integrin beta-5 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-64 of the amino acid sequence represented by UniProtKB:O70309-1. Example: UniProtKB:O70309-1, Cys-64, MOD:00765." [IEDB_epitope:2089290, PRO:DNx]


organism-gene



PR:P18084

integrin beta-5 (human)

hITGB5


"An integrin beta-5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P18084]


organism-modification



PR:000048071

integrin beta-5, signal peptide removed form (human)

hITGB5/SigPep-


"An integrin beta-5 (human) that has had the signal peptide removed. UniProtKB:P18084, 24-799." [PRO:DNx, Reactome:R-HSA-1236749, Reactome:R-HSA-215948]


organism-modification



PR:000070822

integrin beta-5 methylated 1 (human)

hITGB5/Me:1


"An integrin beta-5 (human) that has been methylated on the residue at the position equivalent to Cys-211 of the amino acid sequence represented by UniProtKB:P18084. UniProtKB:P18084, Cys-211, MOD:00660." [IEDB_epitope:1024785, PRO:DNx]


organism-modification



PR:000073361

integrin beta-5 deaminated 1 (human)

hITGB5/Deam:1


"An integrin beta-5 (human) that has been deaminated on the residue at the position equivalent to Asn-505 of the amino acid sequence represented by UniProtKB:P18084. UniProtKB:P18084, Asn-505, MOD:00684." [IEDB_epitope:1979925, PRO:DNx]


organism-modification



PR:000073676

integrin beta-5 cysteinylated 1 (human)

hITGB5/Cyst:1


"An integrin beta-5 (human) that has been cysteinylated on the residue at the position equivalent to Cys-211 of the amino acid sequence represented by UniProtKB:P18084. UniProtKB:P18084, Cys-211, MOD:00765." [IEDB_epitope:1024784, PRO:DNx]


organism-modification



PR:000075136

integrin beta-5 cysteinylated 2 (human)

hITGB5/Cyst:2


"An integrin beta-5 (human) that has been cysteinylated on the residue at the position equivalent to Cys-202 of the amino acid sequence represented by UniProtKB:P18084. UniProtKB:P18084, Cys-202, MOD:00765." [IEDB_epitope:2127968, PRO:DNx]


organism-modification



PR:000080829

integrin beta-5 deaminated 2 (human)

hITGB5/Deam:2


"An integrin beta-5 (human) that has been deaminated on the residue at the position equivalent to Asn-117 of the amino acid sequence represented by UniProtKB:P18084. UniProtKB:P18084, Asn-117, MOD:00684." [IEDB_epitope:1582201, PRO:DNx]


gene



PR:000009142

integrin beta-6

ITGB6


"An integrin beta that is a translation product of the human ITGB6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P18564

integrin beta-6 (human)

hITGB6


"An integrin beta-6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P18564]


organism-sequence



PR:P18564-1

integrin beta-6 isoform h1 (human)

hITGB6/iso:h1


"An integrin beta-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18564-1." [PRO:DNx, UniProtKB:P18564]


organism-sequence



PR:P18564-2

integrin beta-6 isoform h2 (human)

hITGB6/iso:h2


"An integrin beta-6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18564-2." [PRO:DNx, UniProtKB:P18564]


organism-modification



PR:000048072

integrin beta-6, signal peptide removed form (human)

hITGB6/SigPep-


"An integrin beta-6 (human) that has had the signal peptide removed. UniProtKB:P18564, 22-788." [PRO:DNx, Reactome:R-HSA-215951]


organism-gene



PR:Q6AYF4

integrin beta-6 (rat)

rITGB6


"An integrin beta-6 that is encoded in the genome of rat." [OMA:Q6AYF4, PRO:DNx]


organism-sequence



PR:Q6AYF4-1

integrin beta-6 isoform 1 (rat)

rITGB6/iso:1


"An integrin beta-6 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q9Z0T9

integrin beta-6 (mouse)

mITGB6


"An integrin beta-6 that is encoded in the genome of mouse." [OMA:Q9Z0T9, PRO:DNx]


organism-sequence



PR:Q9Z0T9-1

integrin beta-6 isoform 1 (mouse)

mITGB6/iso:1


"An integrin beta-6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000044323

integrin beta-6 isoform 1

ITGB6/iso:1


"An integrin beta-6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z0T9-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:Q6AYF4-1

integrin beta-6 isoform 1 (rat)

rITGB6/iso:1


"An integrin beta-6 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q9Z0T9-1

integrin beta-6 isoform 1 (mouse)

mITGB6/iso:1


"An integrin beta-6 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000009143

integrin beta-7

ITGB7


"An integrin beta that is a translation product of the human ITGB7 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P26010

integrin beta-7 (human)

hITGB7


"An integrin beta-7 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P26010]


organism-sequence



PR:P26010-1

integrin beta-7 isoform 1 (human)

hITGB7/iso:1


"An integrin beta-7 isoform 1 that is encoded in the genome of human." [PRO:CNx]


organism-modification



PR:000026923

integrin beta-7 isoform 1, signal peptide removed form (human)

hITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1, signal peptide removed form in human. UniProtKB:P26010-1, 20-798." [PRO:CNx]


organism-sequence



PR:P26010-2

integrin beta-7 isoform Short (human)

hITGB7/iso:Short


"An integrin beta-7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26010-2." [PRO:DNx, UniProtKB:P26010]


organism-modification



PR:000068022

integrin beta-7 methylated 1 (human)

hITGB7/Me:1


"An integrin beta-7 (human) that has been methylated on the residue at the position equivalent to Cys-654 of the amino acid sequence represented by UniProtKB:P26010-1. Example: UniProtKB:P26010-1, Cys-654, MOD:00660." [IEDB_epitope:998090, IEDB_epitope:998091, PRO:DNx]


organism-modification



PR:000068991

integrin beta-7 methylated 2 (human)

hITGB7/Me:2


"An integrin beta-7 (human) that has been methylated on the residue at the position equivalent to Cys-537 of the amino acid sequence represented by UniProtKB:P26010-1. Example: UniProtKB:P26010-1, Cys-537, MOD:00660." [IEDB_epitope:1016802, PRO:DNx]


organism-modification



PR:000072991

integrin beta-7 methylated 3 (human)

hITGB7/Me:3


"An integrin beta-7 (human) that has been methylated on the residue at the position equivalent to Cys-670 of the amino acid sequence represented by UniProtKB:P26010-1. Example: UniProtKB:P26010-1, Cys-670, MOD:00660." [IEDB_epitope:1053100, PRO:DNx]


organism-modification



PR:000078799

integrin beta-7 methylated 4 (human)

hITGB7/Me:4


"An integrin beta-7 (human) that has been methylated on the residue at the position equivalent to Cys-448 of the amino acid sequence represented by UniProtKB:P26010-1. Example: UniProtKB:P26010-1, Cys-448, MOD:00660." [IEDB_epitope:1054013, IEDB_epitope:1054014, PRO:DNx]


organism-modification



PR:000083766

integrin beta-7 methylated 5 (human)

hITGB7/Me:5


"An integrin beta-7 (human) that has been methylated on the residue at the position equivalent to Cys-271 of the amino acid sequence represented by UniProtKB:P26010-1. Example: UniProtKB:P26010-1, Cys-271, MOD:00660." [IEDB_epitope:1000219, PRO:DNx]


organism-modification



PR:000083855

integrin beta-7 deaminated 1 (human)

hITGB7/Deam:1


"An integrin beta-7 (human) that has been deaminated on the residue at the position equivalent to Asn-434 of the amino acid sequence represented by UniProtKB:P26010-1. Example: UniProtKB:P26010-1, Asn-434, MOD:00684." [IEDB_epitope:495837, IEDB_epitope:495838, IEDB_epitope:760936, IEDB_epitope:893155, PRO:DNx]


organism-modification



PR:000085844

integrin beta-7, signal peptide removed form (human)

hITGB7/SigPep-


"An integrin beta-7 (human) that has had the signal peptide removed. Example: UniProtKB:P26010-1, 20-798." [PRO:DNx, Reactome:R-HSA-3006427]


organism-modification



PR:000026923

integrin beta-7 isoform 1, signal peptide removed form (human)

hITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1, signal peptide removed form in human. UniProtKB:P26010-1, 20-798." [PRO:CNx]


organism-gene



PR:P26011

integrin beta-7 (mouse)

mITGB7


"An integrin beta-7 that is encoded in the genome of mouse." [OMA:P26011, PRO:DNx]


sequence



PR:000026920

integrin beta-7 isoform 1

ITGB7/iso:1


"An integrin beta-7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26010-1 or a 1:1 ortholog thereof." [PRO:CNx]


organism-sequence



PR:P26010-1

integrin beta-7 isoform 1 (human)

hITGB7/iso:1


"An integrin beta-7 isoform 1 that is encoded in the genome of human." [PRO:CNx]


organism-modification



PR:000026923

integrin beta-7 isoform 1, signal peptide removed form (human)

hITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1, signal peptide removed form in human. UniProtKB:P26010-1, 20-798." [PRO:CNx]


modification



PR:000026922

integrin beta-7 isoform 1, signal peptide removed form

ITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1 that has had the signal peptide removed. Example: UniProtKB:P26010-1, 20-798." [PRO:CNx]


organism-modification



PR:000026923

integrin beta-7 isoform 1, signal peptide removed form (human)

hITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1, signal peptide removed form in human. UniProtKB:P26010-1, 20-798." [PRO:CNx]


modification



PR:000020347

integrin beta-7, signal peptide removed form

ITGB7/SigPep-


"An integrin beta-7 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026922

integrin beta-7 isoform 1, signal peptide removed form

ITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1 that has had the signal peptide removed. Example: UniProtKB:P26010-1, 20-798." [PRO:CNx]


organism-modification



PR:000026923

integrin beta-7 isoform 1, signal peptide removed form (human)

hITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1, signal peptide removed form in human. UniProtKB:P26010-1, 20-798." [PRO:CNx]


organism-modification



PR:000085844

integrin beta-7, signal peptide removed form (human)

hITGB7/SigPep-


"An integrin beta-7 (human) that has had the signal peptide removed. Example: UniProtKB:P26010-1, 20-798." [PRO:DNx, Reactome:R-HSA-3006427]


organism-modification



PR:000026923

integrin beta-7 isoform 1, signal peptide removed form (human)

hITGB7/iso:1/SigPep-


"An integrin beta-7 isoform 1, signal peptide removed form in human. UniProtKB:P26010-1, 20-798." [PRO:CNx]


gene



PR:000009144

integrin beta-8

ITGB8


"An integrin beta that is a translation product of the human ITGB8 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P26012

integrin beta-8 (human)

hITGB8


"An integrin beta-8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P26012]


organism-sequence



PR:P26012-1

integrin beta-8 isoform h1 (human)

hITGB8/iso:h1


"An integrin beta-8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26012-1." [PRO:DNx, UniProtKB:P26012]


organism-sequence



PR:P26012-2

integrin beta-8 isoform h2 (human)

hITGB8/iso:h2


"An integrin beta-8 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P26012-2." [PRO:DNx, UniProtKB:P26012]


organism-modification



PR:000048073

integrin beta-8, signal peptide removed form (human)

hITGB8/SigPep-


"An integrin beta-8 (human) that has had the signal peptide removed. UniProtKB:P26012, 43-769." [PRO:DNx, Reactome:R-HSA-216318]


organism-gene



PR:Q0VBD0

integrin beta-8 (mouse)

mITGB8


"An integrin beta-8 that is encoded in the genome of mouse." [OMA:Q0VBD0, PRO:DNx]


gene



PR:000009192

integrin beta-2-like protein

Itgb2l


"An integrin beta that is a translation product of the mouse Itgb2l gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q3UV74

integrin beta-2-like protein (mouse)

mItgb2l


"An integrin beta-2-like protein that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:Q3UV74]


organism-sequence



PR:Q3UV74-1

integrin beta-2-like protein isoform m1 (mouse)

mItgb2l/iso:m1


"An integrin beta-2-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UV74-1." [PRO:DNx, UniProtKB:Q3UV74]


organism-sequence



PR:Q3UV74-2

integrin beta-2-like protein isoform m2 (mouse)

mItgb2l/iso:m2


"An integrin beta-2-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UV74-2." [PRO:DNx, UniProtKB:Q3UV74]


organism-sequence



PR:Q3UV74-3

integrin beta-2-like protein isoform m3 (mouse)

mItgb2l/iso:m3


"An integrin beta-2-like protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3UV74-3." [PRO:DNx, UniProtKB:Q3UV74]


Back to top
ICOS forms found in complexes   

ICOS Component
Complexes
PR:000027392 hITGB2/SigPep- PR:000027308 alphaM-beta2 integrin complex (human)
PR:000028431 integrin alphaMbeta2:JAM3 (human)
PR:000028447 LFA-1:JAM-A (human)
PR:000028415 hITGB1/SigPep- PR:000028448 ILK:integrin beta-1 (human)
PR:000041631 hITGB3/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P09055-1 mITGB1/iso:beta-1A acts_upstream_of_or_withinGO:0016477 cell migration MGI_ref:1203253; PMID:9553049
PR:P09055-2 mITGB1/iso:beta-1D
This isoform contains a unique alternatively spliced cytoplasmic domain of 50 amino acids, with the last 24 amino acids encoded by an additional exon, 11 of these are in common with the isoform beta-1A
acts_upstream_of_or_withinGO:0048738 cardiac muscle tissue development MGI_ref:1203253; PMID:9553049