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Protein Ontology report - integrin beta
PR:000001861 - http://purl.obolibrary.org/obo/PR_000001861
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001861   
  PRO nameintegrin beta 
  Definition"A protein with core architecture consisting of a large extracellular region containing one Integrin, beta chain domain (Pfam:PF00362), up to four EGF-like domains (Pfam:PF07974), and an Integrin beta tail domain (Pfam:PF07965), followed by a single-pass transmembrane region and a small cytoplasmic region often containing an Integrin beta cytoplasmic domain (Pfam:PF08725)." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene8                                                  Organism-Gene 20                                        
         Sequence7                                                  Organism-Sequence 23                                        
         Modification4                                                  Organism-Modification 47                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002512
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001861 integrin beta
ICOS

gene


PR:000002040 integrin beta-1
ITGB1

organism-gene


PR:P05556 integrin beta-1 (human)
hITGB1

organism-sequence


PR:P05556-1 integrin beta-1 isoform beta-1A (human)
hITGB1/iso:beta-1A

organism-sequence


PR:P05556-2 integrin beta-1 isoform beta-1B (human)
hITGB1/iso:beta-1B

organism-sequence


PR:P05556-3 integrin beta-1 isoform beta-1C (human)
hITGB1/iso:beta-1C

organism-sequence


PR:P05556-4 integrin beta-1 isoform beta-1C-2 (human)
hITGB1/iso:beta-1C-2

organism-sequence


PR:P05556-5 integrin beta-1 isoform beta-1D (human)
hITGB1/iso:beta-1D

organism-modification


PR:000028415 integrin beta-1, signal peptide removed form (human)
hITGB1/SigPep-

Yes
organism-modification


PR:000053565 integrin beta-1 N-glycosylated 1 (human)
hITGB1/NGlyco:1

organism-modification


PR:000053566 integrin beta-1 N-glycosylated 2 (human)
hITGB1/NGlyco:2

organism-modification


PR:000053567 integrin beta-1 N-glycosylated 3 (human)
hITGB1/NGlyco:3

organism-modification


PR:000053568 integrin beta-1 N-glycosylated 4 (human)
hITGB1/NGlyco:4

organism-modification


PR:000066244 integrin beta-1 deaminated 1 (human)
hITGB1/Deam:1

organism-modification


PR:000066932 integrin beta-1 methylated 1 (human)
hITGB1/Me:1

organism-modification


PR:000070391 integrin beta-1 cysteinylated 1 (human)
hITGB1/Cyst:1

organism-modification


PR:000072780 integrin beta-1 cysteinylated 2 (human)
hITGB1/Cyst:2

organism-modification


PR:000075713 integrin beta-1 cysteinylated 3 (human)
hITGB1/Cyst:3

organism-modification


PR:000083387 integrin beta-1 cysteinylated 4 (human)
hITGB1/Cyst:4

organism-gene


PR:P09055 integrin beta-1 (mouse)
mITGB1

organism-sequence


PR:P09055-1 integrin beta-1 isoform beta-1A (mouse)
mITGB1/iso:beta-1A
Yes
organism-sequence


PR:P09055-2 integrin beta-1 isoform beta-1D (mouse)
mITGB1/iso:beta-1D
Yes
organism-gene


PR:P11584 integrin beta-PS (fruit fly)
fly-ITGB1

organism-gene


PR:P49134 integrin beta-1 (rat)
rITGB1

organism-gene


PR:Q27874 integrin beta pat-3 (worm)
ITGB1 (worm)

sequence


PR:000037153 integrin beta-1 isoform beta-1A
ITGB1/iso:beta-1A

organism-sequence


PR:P05556-1 integrin beta-1 isoform beta-1A (human)
hITGB1/iso:beta-1A

organism-sequence


PR:P09055-1 integrin beta-1 isoform beta-1A (mouse)
mITGB1/iso:beta-1A
Yes
sequence


PR:000037155 integrin beta-1 isoform beta-1B
ITGB1/iso:beta-1B

organism-sequence


PR:P05556-2 integrin beta-1 isoform beta-1B (human)
hITGB1/iso:beta-1B

sequence


PR:000037157 integrin beta-1 isoform beta-1C
ITGB1/iso:beta-1C

organism-sequence


PR:P05556-3 integrin beta-1 isoform beta-1C (human)
hITGB1/iso:beta-1C

sequence


PR:000037159 integrin beta-1 isoform beta-1C-2
ITGB1/iso:beta-1C-2

organism-sequence


PR:P05556-4 integrin beta-1 isoform beta-1C-2 (human)
hITGB1/iso:beta-1C-2

sequence


PR:000037161 integrin beta-1 isoform beta-1D
ITGB1/iso:beta-1D

organism-sequence


PR:P05556-5 integrin beta-1 isoform beta-1D (human)
hITGB1/iso:beta-1D

organism-sequence


PR:P09055-2 integrin beta-1 isoform beta-1D (mouse)
mITGB1/iso:beta-1D
Yes
modification


PR:000018706 integrin beta-1, signal peptide removed form
ITGB1/SigPep-

organism-modification


PR:000028415 integrin beta-1, signal peptide removed form (human)
hITGB1/SigPep-

Yes
gene


PR:000002041 integrin beta-2
ITGB2

organism-gene


PR:P05107 integrin beta-2 (human)
hITGB2

organism-modification


PR:000027392 integrin beta-2, signal peptide removed form (human)
hITGB2/SigPep-

Yes
organism-modification


PR:000045640 integrin beta-2 phosphorylated 1 (human)
hITGB2/Phos:1

organism-modification


PR:000065133 integrin beta-2 deaminated 1 (human)
hITGB2/Deam:1

organism-modification


PR:000067365 integrin beta-2 methylated 1 (human)
hITGB2/Me:1

organism-modification


PR:000067820 integrin beta-2 methylated 2 (human)
hITGB2/Me:2

organism-modification


PR:000068275 integrin beta-2 cysteinylated 1 (human)
hITGB2/Cyst:1

organism-modification


PR:000068460 integrin beta-2 methylated 3 (human)
hITGB2/Me:3

organism-modification


PR:000068638 integrin beta-2 deaminated 2 (human)
hITGB2/Deam:2

organism-modification


PR:000069019 integrin beta-2 methylated 4 (human)
hITGB2/Me:4

organism-modification


PR:000072514 integrin beta-2 cysteinylated 2 (human)
hITGB2/Cyst:2

organism-modification


PR:000075467 integrin beta-2 methylated 5 (human)
hITGB2/Me:5

organism-modification


PR:000083963 integrin beta-2 cysteinylated 3 (human)
hITGB2/Cyst:3

organism-modification


PR:000084585 integrin beta-2 deaminated 3 (human)
hITGB2/Deam:3

organism-modification


PR:000085443 integrin beta-2 cysteinylated 4 (human)
hITGB2/Cyst:4

organism-gene


PR:P11835 integrin beta-2 (mouse)
mITGB2

modification


PR:000018708 integrin beta-2, signal peptide removed form
ITGB2/SigPep-

organism-modification


PR:000027392 integrin beta-2, signal peptide removed form (human)
hITGB2/SigPep-

Yes
gene


PR:000002042 integrin beta-3
ITGB3

organism-gene


PR:O54890 integrin beta-3 (mouse)
mITGB3

organism-gene


PR:P05106 integrin beta-3 (human)
hITGB3

organism-sequence


PR:P05106-1 integrin beta-3 isoform hBeta-3A (human)
hITGB3/iso:hBeta-3A

organism-sequence


PR:P05106-2 integrin beta-3 isoform hBeta-3B (human)
hITGB3/iso:hBeta-3B

organism-sequence


PR:P05106-3 integrin beta-3 isoform hBeta-3C (human)
hITGB3/iso:hBeta-3C

organism-modification


PR:000041631 integrin beta-3, signal peptide removed form (human)
hITGB3/SigPep-

Yes
organism-modification


PR:000048069 integrin beta-3, signal peptide removed phosphorylated 1 (human)
hITGB3/SigPep-/Phos:1

organism-modification


PR:000053450 integrin beta-3 N-glycosylated 1 (human)
hITGB3/NGlyco:1

organism-modification


PR:000053451 integrin beta-3 N-glycosylated 2 (human)
hITGB3/NGlyco:2

organism-modification


PR:000076948 integrin beta-3 cysteinylated 1 (human)
hITGB3/Cyst:1

organism-gene


PR:Q8R2H2 integrin beta-3 (rat)
rITGB3

gene


PR:000009141 integrin beta-5
ITGB5

organism-gene


PR:O70309 integrin beta-5 (mouse)
mITGB5

organism-sequence


PR:O70309-1 integrin beta-5 isoform mBeta-5A (mouse)
mITGB5/iso:mBeta-5A

organism-sequence


PR:O70309-2 integrin beta-5 isoform mBeta-5B (mouse)
mITGB5/iso:mBeta-5B

organism-modification


PR:000074127 integrin beta-5 cysteinylated 1 (mouse)
mITGB5/Cyst:1

organism-gene


PR:P18084 integrin beta-5 (human)
hITGB5

organism-modification


PR:000048071 integrin beta-5, signal peptide removed form (human)
hITGB5/SigPep-

organism-modification


PR:000070822 integrin beta-5 methylated 1 (human)
hITGB5/Me:1

organism-modification


PR:000073361 integrin beta-5 deaminated 1 (human)
hITGB5/Deam:1

organism-modification


PR:000073676 integrin beta-5 cysteinylated 1 (human)
hITGB5/Cyst:1

organism-modification


PR:000075136 integrin beta-5 cysteinylated 2 (human)
hITGB5/Cyst:2

organism-modification


PR:000080829 integrin beta-5 deaminated 2 (human)
hITGB5/Deam:2

gene


PR:000009142 integrin beta-6
ITGB6

organism-gene


PR:P18564 integrin beta-6 (human)
hITGB6

organism-sequence


PR:P18564-1 integrin beta-6 isoform h1 (human)
hITGB6/iso:h1

organism-sequence


PR:P18564-2 integrin beta-6 isoform h2 (human)
hITGB6/iso:h2

organism-modification


PR:000048072 integrin beta-6, signal peptide removed form (human)
hITGB6/SigPep-

organism-gene


PR:Q6AYF4 integrin beta-6 (rat)
rITGB6

organism-sequence


PR:Q6AYF4-1 integrin beta-6 isoform 1 (rat)
rITGB6/iso:1

organism-gene


PR:Q9Z0T9 integrin beta-6 (mouse)
mITGB6

organism-sequence


PR:Q9Z0T9-1 integrin beta-6 isoform 1 (mouse)
mITGB6/iso:1

sequence


PR:000044323 integrin beta-6 isoform 1
ITGB6/iso:1

organism-sequence


PR:Q6AYF4-1 integrin beta-6 isoform 1 (rat)
rITGB6/iso:1

organism-sequence


PR:Q9Z0T9-1 integrin beta-6 isoform 1 (mouse)
mITGB6/iso:1

gene


PR:000009143 integrin beta-7
ITGB7

organism-gene


PR:P26010 integrin beta-7 (human)
hITGB7

organism-sequence


PR:P26010-1 integrin beta-7 isoform 1 (human)
hITGB7/iso:1

organism-modification


PR:000026923 integrin beta-7 isoform 1, signal peptide removed form (human)
hITGB7/iso:1/SigPep-

organism-sequence


PR:P26010-2 integrin beta-7 isoform Short (human)
hITGB7/iso:Short

organism-modification


PR:000068022 integrin beta-7 methylated 1 (human)
hITGB7/Me:1

organism-modification


PR:000068991 integrin beta-7 methylated 2 (human)
hITGB7/Me:2

organism-modification


PR:000072991 integrin beta-7 methylated 3 (human)
hITGB7/Me:3

organism-modification


PR:000078799 integrin beta-7 methylated 4 (human)
hITGB7/Me:4

organism-modification


PR:000083766 integrin beta-7 methylated 5 (human)
hITGB7/Me:5

organism-modification


PR:000083855 integrin beta-7 deaminated 1 (human)
hITGB7/Deam:1

organism-modification


PR:000085844 integrin beta-7, signal peptide removed form (human)
hITGB7/SigPep-

organism-modification


PR:000026923 integrin beta-7 isoform 1, signal peptide removed form (human)
hITGB7/iso:1/SigPep-

organism-gene


PR:P26011 integrin beta-7 (mouse)
mITGB7

sequence


PR:000026920 integrin beta-7 isoform 1
ITGB7/iso:1

organism-sequence


PR:P26010-1 integrin beta-7 isoform 1 (human)
hITGB7/iso:1

organism-modification


PR:000026923 integrin beta-7 isoform 1, signal peptide removed form (human)
hITGB7/iso:1/SigPep-

modification


PR:000026922 integrin beta-7 isoform 1, signal peptide removed form
ITGB7/iso:1/SigPep-

organism-modification


PR:000026923 integrin beta-7 isoform 1, signal peptide removed form (human)
hITGB7/iso:1/SigPep-

modification


PR:000020347 integrin beta-7, signal peptide removed form
ITGB7/SigPep-

modification


PR:000026922 integrin beta-7 isoform 1, signal peptide removed form
ITGB7/iso:1/SigPep-

organism-modification


PR:000026923 integrin beta-7 isoform 1, signal peptide removed form (human)
hITGB7/iso:1/SigPep-

organism-modification


PR:000085844 integrin beta-7, signal peptide removed form (human)
hITGB7/SigPep-

organism-modification


PR:000026923 integrin beta-7 isoform 1, signal peptide removed form (human)
hITGB7/iso:1/SigPep-

gene


PR:000009144 integrin beta-8
ITGB8

organism-gene


PR:P26012 integrin beta-8 (human)
hITGB8

organism-sequence


PR:P26012-1 integrin beta-8 isoform h1 (human)
hITGB8/iso:h1

organism-sequence


PR:P26012-2 integrin beta-8 isoform h2 (human)
hITGB8/iso:h2

organism-modification


PR:000048073 integrin beta-8, signal peptide removed form (human)
hITGB8/SigPep-

organism-gene


PR:Q0VBD0 integrin beta-8 (mouse)
mITGB8

gene


PR:000009192 integrin beta-2-like protein
Itgb2l

organism-gene


PR:Q3UV74 integrin beta-2-like protein (mouse)
mItgb2l

organism-sequence


PR:Q3UV74-1 integrin beta-2-like protein isoform m1 (mouse)
mItgb2l/iso:m1

organism-sequence


PR:Q3UV74-2 integrin beta-2-like protein isoform m2 (mouse)
mItgb2l/iso:m2

organism-sequence


PR:Q3UV74-3 integrin beta-2-like protein isoform m3 (mouse)
mItgb2l/iso:m3

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ICOS forms found in complexes   

ICOS Component
 Complexes
PR:000027392 hITGB2/SigPep- PR:000027308 alphaM-beta2 integrin complex (human)
PR:000028431 integrin alphaMbeta2:JAM3 (human)
PR:000028447 LFA-1:JAM-A (human)
PR:000028415 hITGB1/SigPep- PR:000028448 ILK:integrin beta-1 (human)
PR:000041631 hITGB3/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P09055-1 mITGB1/iso:beta-1A acts_upstream_of_or_withinGO:0016477 cell migration MGI_ref:1203253; PMID:9553049
PR:P09055-2 mITGB1/iso:beta-1D
This isoform contains a unique alternatively spliced cytoplasmic domain of 50 amino acids, with the last 24 amino acids encoded by an additional exon, 11 of these are in common with the isoform beta-1A		 acts_upstream_of_or_withinGO:0048738 cardiac muscle tissue development MGI_ref:1203253; PMID:9553049