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Protein Ontology report - inducible T-cell costimulator
PR:000001860 - http://purl.obolibrary.org/obo/PR_000001860
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001860   
  PRO nameinducible T-cell costimulator 
  Synonyms
PRO-Short-label: EXACT:ICOS
Gene-based: RELATED:AILIM
Other: EXACT:activation-inducible lymphocyte immunomediatory molecule | CCLP | CD278 | CD28 and CTLA-4-like protein | CD28-related protein 1
RELATED:CRP-1
  Definition"A protein that is a translation product of the human ICOS gene or a 1:1 ortholog thereof." [PRO:WCB] 
  CommentRequested by=CL. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2939
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001860
inducible T-cell costimulator
ICOS
"A protein that is a translation product of the human ICOS gene or a 1:1 ortholog thereof." [PRO:WCB]

organism-gene


PR:Q9R1T7
inducible T-cell costimulator (rat)
rICOS
"An inducible T-cell costimulator that is encoded in the genome of rat." [OMA:Q9R1T7, PRO:DNx]

organism-sequence


PR:Q9R1T7-1
inducible T-cell costimulator isoform r1 (rat)
rICOS/iso:r1
"An inducible T-cell costimulator (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R1T7-1." [PRO:DNx, UniProtKB:Q9R1T7]

organism-sequence


PR:Q9R1T7-2
inducible T-cell costimulator isoform r2 (rat)
rICOS/iso:r2
"An inducible T-cell costimulator (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9R1T7-2." [PRO:DNx, UniProtKB:Q9R1T7]

organism-gene


PR:Q9WVS0
inducible T-cell costimulator (mouse)
mICOS
"An inducible T-cell costimulator that is encoded in the genome of mouse." [OMA:Q9WVS0, PRO:DNx]

organism-sequence


PR:Q9WVS0-1
inducible T-cell costimulator isoform 1 (mouse)
mICOS/iso:1
"An inducible T-cell costimulator isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

organism-gene


PR:Q9Y6W8
inducible T-cell costimulator (human)
hICOS
"An inducible T-cell costimulator that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9Y6W8]

organism-sequence


PR:Q9Y6W8-1
inducible T-cell costimulator isoform 1 (human)
hICOS/iso:1
"An inducible T-cell costimulator isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026927
inducible T-cell costimulator isoform 1, signal peptide removed form (human)
hICOS/iso:1/SigPep-
"An inducible T-cell costimulator isoform 1, signal peptide removed form in human. UniProtKB:Q9Y6W8-1, 21-199." [PRO:CNx, Reactome:R-HSA-198144]

organism-modification


PR:000060797
inducible T-cell costimulator isoform 1, signal peptide removed phosphorylated 1 (human)
hICOS/iso:1/SigPep-/Phos:1
"An inducible T-cell costimulator isoform 1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Tyr-180 of the amino acid sequence represented by UniProtKB:Q9Y6W8-1. UniProtKB:Q9Y6W8-1, 21-199, Tyr-180, MOD:00048." [PRO:DNx, Reactome:R-HSA-389927]

organism-sequence


PR:Q9Y6W8-2
inducible T-cell costimulator isoform h2 (human)
hICOS/iso:h2
"An inducible T-cell costimulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6W8-2." [PRO:DNx, UniProtKB:Q9Y6W8]

organism-modification


PR:000085947
inducible T-cell costimulator, signal peptide removed form (human)
hICOS/SigPep-
"An inducible T-cell costimulator (human) that has had the signal peptide removed. Example: UniProtKB:Q9Y6W8-1, 21-199." [PRO:DNx, Reactome:R-HSA-9845023]

organism-modification


PR:000026927
inducible T-cell costimulator isoform 1, signal peptide removed form (human)
hICOS/iso:1/SigPep-
"An inducible T-cell costimulator isoform 1, signal peptide removed form in human. UniProtKB:Q9Y6W8-1, 21-199." [PRO:CNx, Reactome:R-HSA-198144]

organism-modification


PR:000060797
inducible T-cell costimulator isoform 1, signal peptide removed phosphorylated 1 (human)
hICOS/iso:1/SigPep-/Phos:1
"An inducible T-cell costimulator isoform 1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Tyr-180 of the amino acid sequence represented by UniProtKB:Q9Y6W8-1. UniProtKB:Q9Y6W8-1, 21-199, Tyr-180, MOD:00048." [PRO:DNx, Reactome:R-HSA-389927]

sequence


PR:000026924
inducible T-cell costimulator isoform 1
ICOS/iso:1
"An inducible T-cell costimulator that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6W8-1 or a 1:1 ortholog thereof." [PRO:CNx]

organism-sequence


PR:Q9WVS0-1
inducible T-cell costimulator isoform 1 (mouse)
mICOS/iso:1
"An inducible T-cell costimulator isoform 1 that is encoded in the genome of mouse." [PRO:CNx]

organism-sequence


PR:Q9Y6W8-1
inducible T-cell costimulator isoform 1 (human)
hICOS/iso:1
"An inducible T-cell costimulator isoform 1 that is encoded in the genome of human." [PRO:CNx]

organism-modification


PR:000026927
inducible T-cell costimulator isoform 1, signal peptide removed form (human)
hICOS/iso:1/SigPep-
"An inducible T-cell costimulator isoform 1, signal peptide removed form in human. UniProtKB:Q9Y6W8-1, 21-199." [PRO:CNx, Reactome:R-HSA-198144]

organism-modification


PR:000060797
inducible T-cell costimulator isoform 1, signal peptide removed phosphorylated 1 (human)
hICOS/iso:1/SigPep-/Phos:1
"An inducible T-cell costimulator isoform 1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Tyr-180 of the amino acid sequence represented by UniProtKB:Q9Y6W8-1. UniProtKB:Q9Y6W8-1, 21-199, Tyr-180, MOD:00048." [PRO:DNx, Reactome:R-HSA-389927]

modification


PR:000026926
inducible T-cell costimulator isoform 1, signal peptide removed form
ICOS/iso:1/SigPep-
"An inducible T-cell costimulator isoform 1 that has had the signal peptide removed. Example: UniProtKB:Q9Y6W8-1, 21-199." [PRO:CNx]

organism-modification


PR:000026927
inducible T-cell costimulator isoform 1, signal peptide removed form (human)
hICOS/iso:1/SigPep-
"An inducible T-cell costimulator isoform 1, signal peptide removed form in human. UniProtKB:Q9Y6W8-1, 21-199." [PRO:CNx, Reactome:R-HSA-198144]

organism-modification


PR:000060797
inducible T-cell costimulator isoform 1, signal peptide removed phosphorylated 1 (human)
hICOS/iso:1/SigPep-/Phos:1
"An inducible T-cell costimulator isoform 1 (human) that has had the signal peptide removed and that has been phosphorylated on the residue at the position equivalent to Tyr-180 of the amino acid sequence represented by UniProtKB:Q9Y6W8-1. UniProtKB:Q9Y6W8-1, 21-199, Tyr-180, MOD:00048." [PRO:DNx, Reactome:R-HSA-389927]