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Protein Ontology report - interleukin-1 receptor-associated kinase-like 2
PR:000001783 - http://purl.obolibrary.org/obo/PR_000001783
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001783   
  PRO nameinterleukin-1 receptor-associated kinase-like 2 
  Synonyms
PRO-Short-label: EXACT:IRAK2
Other: EXACT:IRAK-2 | mu-IRAK-2
  Definition"An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK2 gene or a 1:1 ortholog thereof. This protein class is inactive as a kinase due to a change of an Asn instead of an Asp redisue in a catalytic site." [PMID:9374458, PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001781 interleukin-1 receptor-associated kinase IRAK1/3
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2043
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001783

interleukin-1 receptor-associated kinase-like 2

IRAK2


"An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK2 gene or a 1:1 ortholog thereof. This protein class is inactive as a kinase due to a change of an Asn instead of an Asp redisue in a catalytic site." [PMID:9374458, PRO:CNA]


organism-gene



PR:F1N826

uncharacterized protein, IRAK2 translation product (chicken)

chick-IRAK2


"An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of chicken." [OMA:F1N826, PRO:DNx]


organism-gene



PR:O43187

interleukin-1 receptor-associated kinase-like 2 (human)

hIRAK2


"An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O43187]


organism-modification



PR:000048045

interleukin-1 receptor-associated kinase-like 2 phosphorylated form (human)

hIRAK2/PhosRes+


"An interleukin-1 receptor-associated kinase-like 2 (human) that includes at least one phosphorylated residue. UniProtKB:O43187, MOD:00696." [PRO:DNx, Reactome:R-HSA-446636, Reactome:R-HSA-936949, Reactome:R-HSA-975187]


organism-modification



PR:000081167

interleukin-1 receptor-associated kinase-like 2 cysteinylated 1 (human)

hIRAK2/Cyst:1


"An interleukin-1 receptor-associated kinase-like 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-470 of the amino acid sequence represented by UniProtKB:O43187. UniProtKB:O43187, Cys-470, MOD:00765." [IEDB_epitope:1578132, PRO:DNx]


organism-modification



PR:000081833

interleukin-1 receptor-associated kinase-like 2 cysteinylated 2 (human)

hIRAK2/Cyst:2


"An interleukin-1 receptor-associated kinase-like 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-261 of the amino acid sequence represented by UniProtKB:O43187. UniProtKB:O43187, Cys-261, MOD:00765." [IEDB_epitope:1857096, PRO:DNx]


organism-modification



PR:000082521

interleukin-1 receptor-associated kinase-like 2 cysteinylated 3 (human)

hIRAK2/Cyst:3


"An interleukin-1 receptor-associated kinase-like 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-79 of the amino acid sequence represented by UniProtKB:O43187. UniProtKB:O43187, Cys-79, MOD:00765." [IEDB_epitope:1333187, PRO:DNx]


organism-gene



PR:Q4QQS0

interleukin-1 receptor-associated kinase-like 2 (rat)

rIRAK2


"An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of rat." [OMA:Q4QQS0, PRO:DNx]


organism-gene



PR:Q8CFA1

interleukin-1 receptor-associated kinase-like 2 (mouse)

mIRAK2


"An interleukin-1 receptor-associated kinase-like 2 that is encoded in the genome of mouse." [OMA:Q8CFA1, PRO:DNx]


organism-sequence



PR:Q8CFA1-1

interleukin-1 receptor-associated kinase-like 2 isoform m1 (mouse)

mIRAK2/iso:m1


"An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-1." [PRO:DNx, UniProtKB:Q8CFA1]


organism-sequence



PR:Q8CFA1-2

interleukin-1 receptor-associated kinase-like 2 isoform m2 (mouse)

mIRAK2/iso:m2


"An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-2." [PRO:DNx, UniProtKB:Q8CFA1]


organism-sequence



PR:Q8CFA1-3

interleukin-1 receptor-associated kinase-like 2 isoform m3 (mouse)

mIRAK2/iso:m3


"An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-3." [PRO:DNx, UniProtKB:Q8CFA1]


organism-sequence



PR:Q8CFA1-4

interleukin-1 receptor-associated kinase-like 2 isoform m4 (mouse)

mIRAK2/iso:m4


"An interleukin-1 receptor-associated kinase-like 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CFA1-4." [PRO:DNx, UniProtKB:Q8CFA1]