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gene
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PR:000001782 |
interleukin-1 receptor-associated kinase 1
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IRAK1
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"An interleukin-1 receptor-associated kinase IRAK1/3 that is a translation product of the human IRAK1 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
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PR:P51617 |
interleukin-1 receptor-associated kinase 1 (human)
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hIRAK1
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"An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:P51617-1 |
interleukin-1 receptor-associated kinase 1 isoform 1 (human)
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hIRAK1/iso:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000027492 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
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hIRAK1/iso:1/Phos:3
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
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Yes |
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organism-modification
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PR:000027493 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
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hIRAK1/iso:1/Phos:4
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
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Yes |
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organism-modification
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PR:000027494 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
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hIRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
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Yes |
Yes |
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organism-modification
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PR:000061935 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human)
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hIRAK1/iso:1/pSerThr+
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"An interleukin-1 receptor-associated kinase 1 isoform 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617-1, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-193904]
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organism-sequence
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PR:P51617-2 |
interleukin-1 receptor-associated kinase 1 isoform h2 (human)
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hIRAK1/iso:h2
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"An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-2." [PRO:DNx, UniProtKB:P51617]
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organism-sequence
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PR:P51617-3 |
interleukin-1 receptor-associated kinase 1 isoform h3 (human)
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hIRAK1/iso:h3
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"An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-3." [PRO:DNx, UniProtKB:P51617]
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organism-sequence
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PR:P51617-4 |
interleukin-1 receptor-associated kinase 1 isoform h4 (human)
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hIRAK1/iso:h4
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"An interleukin-1 receptor-associated kinase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-4." [PRO:DNx, UniProtKB:P51617]
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organism-modification
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PR:000048042 |
interleukin-1 receptor-associated kinase 1 phosphorylated 5 (human)
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hIRAK1/Phos:5
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"An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-376, and phosphothreonine at position 387 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Ser-376, MOD:00046|Thr-387, MOD:00047." [PRO:DNx, Reactome:R-HSA-446687]
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organism-modification
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PR:000048043 |
interleukin-1 receptor-associated kinase 1 phosphorylated 1 (human)
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hIRAK1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-209 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Thr-209, MOD:00047." [PRO:DNx, Reactome:R-HSA-937031, Reactome:R-HSA-975189]
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organism-modification
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PR:000048044 |
interleukin-1 receptor-associated kinase 1 phosphorylated 3 (human)
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hIRAK1/Phos:3
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"An interleukin-1 receptor-associated kinase 1 (human) that has been post-translationally modified to include phosphothreonine at positions 209 and 387 of the amino acid sequence represented by UniProtKB:P51617. UniProtKB:P51617, Thr-209/Thr-387, MOD:00047." [PRO:DNx, Reactome:R-HSA-166279, Reactome:R-HSA-975117]
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organism-modification
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PR:000062298 |
interleukin-1 receptor-associated kinase 1 phosphorylated 2 (human)
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hIRAK1/Phos:2
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"An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-209, Ser-376, and Thr-387 of the amino acid sequence represented by UniProtKB:P51617-1 and that includes at least one additional phosphorylated threonine and at least two additional phosphorylated serines. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|Ser-376, MOD:00046|MOD:00046(2+)|MOD:00047." [PRO:DNx, Reactome:R-HSA-446682, Reactome:R-HSA-937011, Reactome:R-HSA-975157]
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organism-modification
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PR:000064197 |
interleukin-1 receptor-associated kinase 1 phosphoserine and phosphothreonine form (human)
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hIRAK1/pSerThr+
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"An interleukin-1 receptor-associated kinase 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-3149574]
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organism-modification
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PR:000064772 |
interleukin-1 receptor-associated kinase 1 phosphorylated and ubiquitinated 1 (human)
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hIRAK1/PhosUbiq:1
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"An interleukin-1 receptor-associated kinase 1 (human) that has been phosphorylated on the residues at the positions equivalent to Thr-209, Ser-376 and Thr-387, and ubiquitinated on the residues at the positions equivalent to Lys-134 and Lys-180 of the amino acid sequence represented by UniProtKB:P51617-1 and that includes at least one additional phosphorylated threonine and at least two additional phosphorylated serines. Example: UniProtKB:P51617-1, Lys-134/Lys-180, MOD:01148|Thr-209/Thr-387, MOD:00047|Ser-376, MOD:00046|MOD:00046(2+)|MOD:00047." [PRO:DNx, Reactome:R-HSA-975112]
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organism-gene
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PR:Q62406 |
interleukin-1 receptor-associated kinase 1 (mouse)
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mIRAK1
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"An interleukin-1 receptor-associated kinase 1 that is encoded in the genome of mouse." [OMA:Q62406, PRO:CNA]
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Yes |
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organism-sequence
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PR:Q62406-1 |
interleukin-1 receptor-associated kinase 1 isoform 1 (mouse)
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mIRAK1/iso:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000027178 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse)
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mIRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q62406-1, Thr-209, MOD:00047." [PMID:12538665, TLR:AMM]
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Yes |
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organism-modification
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PR:000027179 |
interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form (mouse)
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mIRAK1/iso:1/UnMod
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"An interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form in mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q62406-2 |
interleukin-1 receptor-associated kinase 1 isoform m2 (mouse)
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mIRAK1/iso:m2
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"An interleukin-1 receptor-associated kinase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q62406-2." [PRO:DNx, UniProtKB:Q62406]
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sequence
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PR:000021973 |
interleukin-1 receptor-associated kinase 1 isoform 1
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IRAK1/iso:1
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"An interleukin-1 receptor-associated kinase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P51617-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:P51617-1 |
interleukin-1 receptor-associated kinase 1 isoform 1 (human)
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hIRAK1/iso:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-modification
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PR:000027492 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
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hIRAK1/iso:1/Phos:3
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
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Yes |
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organism-modification
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PR:000027493 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
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hIRAK1/iso:1/Phos:4
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
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Yes |
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organism-modification
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PR:000027494 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
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hIRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
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Yes |
Yes |
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organism-modification
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PR:000061935 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human)
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hIRAK1/iso:1/pSerThr+
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"An interleukin-1 receptor-associated kinase 1 isoform 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617-1, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-193904]
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organism-sequence
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PR:Q62406-1 |
interleukin-1 receptor-associated kinase 1 isoform 1 (mouse)
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mIRAK1/iso:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-modification
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PR:000027178 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse)
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mIRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q62406-1, Thr-209, MOD:00047." [PMID:12538665, TLR:AMM]
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Yes |
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organism-modification
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PR:000027179 |
interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form (mouse)
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mIRAK1/iso:1/UnMod
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"An interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form in mouse." [PRO:CNA]
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Yes |
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modification
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PR:000021971 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form
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IRAK1/iso:1/PhosRes+
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"An interleukin-1 receptor-associated kinase 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000021975 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1
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IRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation by interleukin-1 receptor-associated kinase 4 (IRAK-4) occurs on the conserved Thr residue (Thr-209 in human) located at the N terminus of the kinase domain. This is the first step following the activation of the TLR/IL-1 receptor complex. This phosphorylation results in a conformational change of the kinase domain. Example: UniProtKB:P51617-1, Thr-209, MOD:00047." [PMID:11960013, PMID:14625308, PRO:CNA, TLR:AMM]
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organism-modification
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PR:000027178 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (mouse)
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mIRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in mouse. UniProtKB:Q62406-1, Thr-209, MOD:00047." [PMID:12538665, TLR:AMM]
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Yes |
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organism-modification
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PR:000027494 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 (human)
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hIRAK1/iso:1/Phos:1
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 1 in human. UniProtKB:P51617-1, Thr-209, MOD:00047." [PRO:DNx, UniProtKB:P51617]
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Yes |
Yes |
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modification
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PR:000021977 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3
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IRAK1/iso:1/Phos:3
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation by interleukin-1 receptor-associated kinase 4 (IRAK-4) occurs on the conserved Thr residue (Thr-209 in human) located near the N terminus of the kinase domain, and on a Thr residue located in the activation loop (Thr-387 in human). The latter phosphorylation is the second step following the activation of the TLR/IL-1 receptor complex. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA, PRO:DAN]
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organism-modification
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PR:000027492 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 (human)
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hIRAK1/iso:1/Phos:3
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 3 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047." [PMID:14625308, PRO:CNA]
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Yes |
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modification
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PR:000021978 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4
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IRAK1/iso:1/Phos:4
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated form in which the phosphorylation occurs by interleukin-1 receptor-associated kinase 4 (IRAK-4) and extensively autophosphorylated in the Pro-, Ser-, and Thr-rich ProST region between the N-terminal death domain and kinase domain. Example: UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA, PRO:DAN]
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organism-modification
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PR:000027493 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 (human)
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hIRAK1/iso:1/Phos:4
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"An interleukin-1 receptor-associated kinase 1 isoform 1 phosphorylated 4 in human. UniProtKB:P51617-1, Thr-209/Thr-387, MOD:00047|MOD:00046." [PMID:14625308, PRO:CNA]
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Yes |
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organism-modification
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PR:000061935 |
interleukin-1 receptor-associated kinase 1 isoform 1 phosphoserine and phosphothreonine form (human)
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hIRAK1/iso:1/pSerThr+
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"An interleukin-1 receptor-associated kinase 1 isoform 1 (human) that includes at least one phosphorylated serine and at least one phosphorylated threonine. UniProtKB:P51617-1, MOD:00046|MOD:00047." [PRO:DNx, Reactome:R-HSA-193904]
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modification
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PR:000021974 |
interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form
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IRAK1/iso:1/UnMod
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"An interleukin-1 receptor-associated kinase 1 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
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organism-modification
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PR:000027179 |
interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form (mouse)
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mIRAK1/iso:1/UnMod
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"An interleukin-1 receptor-associated kinase 1 isoform 1 unmodified form in mouse." [PRO:CNA]
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Yes |
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