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family
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PR:000001777 |
IKK-related kinase
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IKBKB
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"A protein that has a core domain composition consisting of one copy of the Protein kinase domain (Pfam:PF00069) at the N terminus, and with average length of about 720 residues. Members of this class have essential roles in innate immunity through signal-induced activation of IRF3 and IRF7." [PMID:18353649, PRO:CNA]
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gene
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PR:000001778 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon
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IKBKE
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"An IKK-related kinase that is a translation product of the human IKBKE gene or a 1:1 ortholog thereof. Members of this class are part of the PMA-inducible IkappaB kinase complex." [PMID:10882136, PRO:CNA]
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organism-gene
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PR:Q14164 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon (human)
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hIKBKE
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is encoded in the genome of human." [PMID:10882136, PMID:17327220, PRO:CNA, UniProtKB:Q14164]
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organism-sequence
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PR:Q14164-1 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 (human)
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hIKBKE/iso:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q14164-2 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform h2 (human)
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hIKBKE/iso:h2
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14164-2." [PRO:DNx, UniProtKB:Q14164]
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organism-modification
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PR:000028691 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1 (human)
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hIKBKE/Phos:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1 in human. Example: UniProtKB:Q14164-1, Ser-172, MOD:00046." [PMID:10421793, PRO:CNA, Reactome:R-HSA-450278]
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Yes |
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organism-modification
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PR:000064755 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated and sumoylated 1 (human)
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hIKBKE/PhosSumo:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon (human) that has been phosphorylated on the residue at the position equivalent to Ser-172 and sumoylated on the residue at the position equivalent to Lys-231 of the amino acid sequence represented by UniProtKB:Q14164-1. Example: UniProtKB:Q14164-1, Ser-172, MOD:00046|Lys-231, MOD:01149." [PRO:DNx, Reactome:R-HSA-4755535]
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organism-gene
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PR:Q9R0T8 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon (mouse)
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mIKBKE
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is encoded in the genome of mouse." [OMA:Q9R0T8, PRO:CNA]
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Yes |
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sequence
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PR:000028688 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1
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IKBKE/iso:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14164-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:Q14164-1 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 (human)
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hIKBKE/iso:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 that is encoded in the genome of human." [PRO:CNA]
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modification
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PR:000028690 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1
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IKBKE/Phos:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon that has been phosphorylated on the residue at the position equivalent to Ser-172 of the amino acid sequence represented by UniProtKB:Q14164-1. Example: UniProtKB:Q14164-1, Ser-172, MOD:00046." [PRO:CNA, PRO:DAN, Reactome:R-HSA-450278]
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organism-modification
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PR:000028691 |
inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1 (human)
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hIKBKE/Phos:1
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"An inhibitor of nuclear factor kappa-B kinase subunit epsilon phosphorylated 1 in human. Example: UniProtKB:Q14164-1, Ser-172, MOD:00046." [PMID:10421793, PRO:CNA, Reactome:R-HSA-450278]
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Yes |
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gene
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PR:000001779 |
serine/threonine-protein kinase TBK1
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TBK1
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"An IKK-related kinase that is a translation product of the human TBK1 gene or a 1:1 ortholog thereof." [PRO:CNA]
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organism-gene
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PR:Q9UHD2 |
serine/threonine-protein kinase TBK1 (human)
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hTBK1
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"A serine/threonine-protein kinase TBK1 that is encoded in the genome of human." [PMID:17327220, PRO:CNA, Reactome:R-HSA-166267]
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organism-sequence
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PR:Q9UHD2-1 |
serine/threonine-protein kinase TBK1 isoform 1 (human)
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hTBK1/iso:1
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"A serine/threonine-protein kinase TBK1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000028695 |
serine/threonine-protein kinase TBK1 phosphorylated 1 (human)
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hTBK1/Phos:1
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"A serine/threonine-protein kinase TBK1 phosphorylated 1 in human. UniProtKB:Q9UHD2, Ser-172, MOD:00046." [PRO:CNA]
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Yes |
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organism-modification
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PR:000045519 |
serine/threonine-protein kinase TBK1 phosphorylated 2 (human)
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hTBK1/Phos:2
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"A serine/threonine-protein kinase TBK1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-527 in UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Ser-527, MOD:00046." [PMID:26407194, PRO:CNA]
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organism-modification
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PR:000064841 |
serine/threonine-protein kinase TBK1 phosphorylated and ubiquitinated 1 (human)
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hTBK1/PhosUbiq:1
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"A serine/threonine-protein kinase TBK1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-172 and ubiquitinated on the residue at the position equivalent to Lys-670 of the amino acid sequence represented by UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Ser-172, MOD:00046|Lys-670, MOD:01148." [PRO:DNx, Reactome:R-HSA-3249397]
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organism-modification
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PR:000066943 |
serine/threonine-protein kinase TBK1 methylated 1 (human)
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hTBK1/Me:1
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"A serine/threonine-protein kinase TBK1 (human) that has been methylated on the residue at the position equivalent to Cys-605 of the amino acid sequence represented by UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Cys-605, MOD:00660." [IEDB_epitope:1013457, PRO:DNx]
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organism-modification
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PR:000068123 |
serine/threonine-protein kinase TBK1 deaminated 1 (human)
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hTBK1/Deam:1
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"A serine/threonine-protein kinase TBK1 (human) that has been deaminated on the residue at the position equivalent to Asn-330 of the amino acid sequence represented by UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Asn-330, MOD:00684." [IEDB_epitope:635471, PRO:DNx]
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organism-modification
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PR:000070007 |
serine/threonine-protein kinase TBK1 cysteinylated 1 (human)
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hTBK1/Cyst:1
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"A serine/threonine-protein kinase TBK1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-605 of the amino acid sequence represented by UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Cys-605, MOD:00765." [IEDB_epitope:878347, PRO:DNx]
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organism-modification
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PR:000075441 |
serine/threonine-protein kinase TBK1 deaminated 2 (human)
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hTBK1/Deam:2
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"A serine/threonine-protein kinase TBK1 (human) that has been deaminated on the residue at the position equivalent to Asn-66 of the amino acid sequence represented by UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Asn-66, MOD:00684." [IEDB_epitope:1800864, PRO:DNx]
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organism-modification
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PR:000077131 |
serine/threonine-protein kinase TBK1 deaminated 3 (human)
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hTBK1/Deam:3
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"A serine/threonine-protein kinase TBK1 (human) that has been deaminated on the residue at the position equivalent to Asn-557 of the amino acid sequence represented by UniProtKB:Q9UHD2. UniProtKB:Q9UHD2, Asn-557, MOD:00684." [IEDB_epitope:1984490, PRO:DNx]
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organism-gene
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PR:Q9WUN2 |
serine/threonine-protein kinase TBK1 (mouse)
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mTBK1
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"A serine/threonine-protein kinase TBK1 that is encoded in the genome of mouse." [OMA:Q9WUN2, PRO:CNA]
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Yes |
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organism-modification
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PR:000080978 |
serine/threonine-protein kinase TBK1 cysteinylated 1 (mouse)
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mTBK1/Cyst:1
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"A serine/threonine-protein kinase TBK1 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-728 of the amino acid sequence represented by UniProtKB:Q9WUN2. UniProtKB:Q9WUN2, Cys-728, MOD:00765." [IEDB_epitope:2094575, PRO:DNx]
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sequence
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PR:000028692 |
serine/threonine-protein kinase TBK1 isoform 1
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TBK1/iso:1
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"A serine/threonine-protein kinase TBK1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UHD2-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:Q9UHD2-1 |
serine/threonine-protein kinase TBK1 isoform 1 (human)
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hTBK1/iso:1
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"A serine/threonine-protein kinase TBK1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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modification
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PR:000028694 |
serine/threonine-protein kinase TBK1 phosphorylated 1
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TBK1/Phos:1
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"A serine/threonine-protein kinase TBK1 that has been phosphorylated on a conserved Ser residue within the Protein Kinase domain (Pfam:PF00069). Example: UniProtKB:Q9UHD2, Ser-172, MOD:00046." [PRO:CNA, Reactome:R-HSA-450290]
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organism-modification
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PR:000028695 |
serine/threonine-protein kinase TBK1 phosphorylated 1 (human)
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hTBK1/Phos:1
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"A serine/threonine-protein kinase TBK1 phosphorylated 1 in human. UniProtKB:Q9UHD2, Ser-172, MOD:00046." [PRO:CNA]
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Yes |
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