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Protein Ontology report - TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
PR:000001770 - http://purl.obolibrary.org/obo/PR_000001770
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000001770   
  PRO nameTGF-beta-activated kinase 1 and MAP3K7-binding protein 1 
  Synonyms
PRO-Short-label: EXACT:TAB1
Gene-based: RELATED:MAP3K7IP1
Other: EXACT:mitogen-activated protein kinase kinase kinase 7-interacting protein 1 | TAK1-binding protein 1 | TGF-beta-activated kinase 1-binding protein 1
  Definition"A protein that is a translation product of the human TAB1 gene or a 1:1 ortholog thereof. It contains a copy of the Protein phosphatase 2C (Pfam:PF00481) domain." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF038188
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001770

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

TAB1


"A protein that is a translation product of the human TAB1 gene or a 1:1 ortholog thereof. It contains a copy of the Protein phosphatase 2C (Pfam:PF00481) domain." [PRO:CNA]


organism-gene



PR:F1NEQ2

uncharacterized protein, TAB1 translation product (chicken)

chick-TAB1


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 that is encoded in the genome of chicken." [OMA:F1NEQ2, PRO:DNx]


organism-gene



PR:G5EEM6

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (worm)

TAB1 (worm)


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 that is encoded in the genome of worm." [OMA:G5EEM6, PRO:DNx]


organism-gene



PR:Q15750

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (human)

hTAB1


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-sequence



PR:Q15750-1

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform h1 (human)

hTAB1/iso:h1


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15750-1." [PRO:DNx, UniProtKB:Q15750]


organism-sequence



PR:Q15750-2

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform h2 (human)

hTAB1/iso:h2


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15750-2." [PRO:DNx, UniProtKB:Q15750]


organism-modification



PR:000073459

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 methylated 1 (human)

hTAB1/Me:1


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-62 of the amino acid sequence represented by UniProtKB:Q15750-1. Example: UniProtKB:Q15750-1, Cys-62, MOD:00660." [IEDB_epitope:1045425, PRO:DNx]


organism-gene



PR:Q8CF89

TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (mouse)

mTAB1


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 that is encoded in the genome of mouse." [OMA:Q8CF89, PRO:CNA]


Yes
organism-gene



PR:Q9LUS8

probable protein phosphatase 2C 40 (Arabidopsis thaliana)

At-TAB1


"A TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9LUS8, PRO:DNx]


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TAB1 forms found in complexes   

TAB1 Component
Complexes
PR:Q15750 hTAB1 PR:000035730 TAK1 kinase complex (human)
PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
PR:000035740 free K63-linked pUb:activated TAK1 complex:pUbtraf6 complex (human)
PR:000037338 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:activated TLR3 complex (human)
PR:000037342 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human)
PR:Q8CF89 mTAB1 PR:000027102 TAK1 kinase complex (mouse)
PR:000027105 TRIKA2 complex (mouse)
PR:000036111 K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036114 IkappaB kinase:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036117 pIKBK:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)