back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - lysophospholipid (S1P) receptor
PR:000001673 - http://purl.obolibrary.org/obo/PR_000001673
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001673   
  PRO namelysophospholipid (S1P) receptor 
  Synonyms
Other: EXACT:sphingosine 1-phosphate receptor 1-5
  Definition"An LPAR1/S1PR1-like lysophospholipid receptor that is a translation product of the human S1PR1, S1PR2, S1PR3, S1PR4, or S1PR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues." [PRO:DAN, PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000001427 LPAR1/S1PR1-like lysophospholipid receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene5                                                  Organism-Gene 15                                        
         Sequence3                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF501018;IUPHARfam:135
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001673

lysophospholipid (S1P) receptor

SSTR5


"An LPAR1/S1PR1-like lysophospholipid receptor that is a translation product of the human S1PR1, S1PR2, S1PR3, S1PR4, or S1PR5 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues." [PRO:DAN, PRO:WCB]


gene



PR:000001706

sphingosine 1-phosphate receptor 1

S1PR1


"A lysophospholipid (S1P) receptor that is a translation product of the human S1PR1 gene or a 1:1 ortholog thereof. The receptor is specifically expressed in endothelial cells, and to a lesser extent, in vascular smooth muscle cells, fibroblasts, melanocytes, and cells of epithelioid origin." [PRO:WCB, UniProtKB:P21453]


organism-gene



PR:O08530

sphingosine 1-phosphate receptor 1 (mouse)

mS1PR1


"A sphingosine 1-phosphate receptor 1 that is encoded in the genome of mouse." [OMA:O08530, PRO:DNx]


organism-sequence



PR:O08530-1

sphingosine 1-phosphate receptor 1 isoform 1 (mouse)

mS1PR1/iso:1


"A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P21453

sphingosine 1-phosphate receptor 1 (human)

hS1PR1


"A sphingosine 1-phosphate receptor 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P21453]


organism-sequence



PR:P21453-1

sphingosine 1-phosphate receptor 1 isoform 1 (human)

hS1PR1/iso:1


"A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045710

sphingosine 1-phosphate receptor 1 phosphorylated 1 (human)

hS1PR1/Phos:1


"A sphingosine 1-phosphate receptor 1 (human) that has been phosphorylated at Thr-236. UniProtKB:P21453, Thr-236, MOD:00047." [iPTMnet:P21453, PMID:11583630]


organism-gene



PR:P48303

sphingosine 1-phosphate receptor 1 (rat)

rS1PR1


"A sphingosine 1-phosphate receptor 1 that is encoded in the genome of rat." [OMA:P48303, PRO:DNx]


organism-modification



PR:000058963

sphingosine 1-phosphate receptor 1 N-glycosylated 1 (rat)

rS1PR1/NGlyco:1


"A sphingosine 1-phosphate receptor 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-31 of the amino acid sequence represented by UniProtKB:P48303-1, in which the glycan structure is represented by GlyTouCan:G30159WR. Example: UniProtKB:P48303-1, Asn-31, MOD:00160~GNO:G30159WR." [GlyGen:P48303-1, PMID:24090084, PRO:DNx]


organism-modification



PR:000058964

sphingosine 1-phosphate receptor 1 N-glycosylated 2 (rat)

rS1PR1/NGlyco:2


"A sphingosine 1-phosphate receptor 1 (rat) that has been N-glycosylated at the residue equivalent to Asn-31 of the amino acid sequence represented by UniProtKB:P48303-1, in which the glycan composition is represented by GlyTouCan:G88725PI. Example: UniProtKB:P48303-1, Asn-31, MOD:00160~GNO:G88725PI." [GlyGen:P48303-1, PMID:24090084, PRO:DNx]


organism-gene



PR:Q9DDK4

sphingosine 1-phosphate receptor 1 (zebrafish)

z-S1PR1


"A sphingosine 1-phosphate receptor 1 that is encoded in the genome of zebrafish." [PRO:WCB]


sequence



PR:000039053

sphingosine 1-phosphate receptor 1 isoform 1

S1PR1/iso:1


"A sphingosine 1-phosphate receptor 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P21453-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O08530-1

sphingosine 1-phosphate receptor 1 isoform 1 (mouse)

mS1PR1/iso:1


"A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P21453-1

sphingosine 1-phosphate receptor 1 isoform 1 (human)

hS1PR1/iso:1


"A sphingosine 1-phosphate receptor 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


gene



PR:000001707

sphingosine 1-phosphate receptor 2

S1PR2


"A lysophospholipid (S1P) receptor that is a translation product of the human S1PR2 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:O95136

sphingosine 1-phosphate receptor 2 (human)

hS1PR2


"A sphingosine 1-phosphate receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O95136]


organism-gene



PR:P47752

sphingosine 1-phosphate receptor 2 (rat)

rS1PR2


"A sphingosine 1-phosphate receptor 2 that is encoded in the genome of rat." [OMA:P47752, PRO:DNx]


organism-sequence



PR:P47752-1

sphingosine 1-phosphate receptor 2 isoform 1 (rat)

rS1PR2/iso:1


"A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P52592

sphingosine 1-phosphate receptor 2 (mouse)

mS1PR2


"A sphingosine 1-phosphate receptor 2 that is encoded in the genome of mouse." [OMA:P52592, PRO:DNx]


organism-sequence



PR:P52592-1

sphingosine 1-phosphate receptor 2 isoform 1 (mouse)

mS1PR2/iso:1


"A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q9I8K8

sphingosine 1-phosphate receptor 2 (zebrafish)

z-S1PR2


"A sphingosine 1-phosphate receptor 2 that is encoded in the genome of zebrafish." [OMA:Q9I8K8, PRO:DNx]


sequence



PR:000039703

sphingosine 1-phosphate receptor 2 isoform 1

S1PR2/iso:1


"A sphingosine 1-phosphate receptor 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52592-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P47752-1

sphingosine 1-phosphate receptor 2 isoform 1 (rat)

rS1PR2/iso:1


"A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P52592-1

sphingosine 1-phosphate receptor 2 isoform 1 (mouse)

mS1PR2/iso:1


"A sphingosine 1-phosphate receptor 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000001708

sphingosine 1-phosphate receptor 3

S1PR3


"A lysophospholipid (S1P) receptor that is a translation product of the human S1PR3 gene or a 1:1 ortholog thereof. It is expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver." [PRO:WCB, UniProtKB:Q99500]


organism-gene



PR:Q99500

sphingosine 1-phosphate receptor 3 (human)

hS1PR3


"A sphingosine 1-phosphate receptor 3 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q99500]


organism-gene



PR:Q9Z0U9

sphingosine 1-phosphate receptor 3 (mouse)

mS1PR3


"A sphingosine 1-phosphate receptor 3 that is encoded in the genome of mouse." [OMA:Q9Z0U9, PRO:DNx]


gene



PR:000001709

sphingosine 1-phosphate receptor 4

S1PR4


"A lysophospholipid (S1P) receptor that is a translation product of the human S1PR4 gene or a 1:1 ortholog thereof. This receptor is specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung." [PRO:WCB, UniProtKB:O95977]


organism-gene



PR:O95977

sphingosine 1-phosphate receptor 4 (human)

hS1PR4


"A sphingosine 1-phosphate receptor 4 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O95977]


organism-modification



PR:000067409

sphingosine 1-phosphate receptor 4 methylated 1 (human)

hS1PR4/Me:1


"A sphingosine 1-phosphate receptor 4 (human) that has been methylated on the residue at the position equivalent to Cys-315 of the amino acid sequence represented by UniProtKB:O95977. UniProtKB:O95977, Cys-315, MOD:00660." [IEDB_epitope:1009903, PRO:DNx]


organism-modification



PR:000070735

sphingosine 1-phosphate receptor 4 deaminated 1 (human)

hS1PR4/Deam:1


"A sphingosine 1-phosphate receptor 4 (human) that has been deaminated on the residue at the position equivalent to Asn-64 of the amino acid sequence represented by UniProtKB:O95977. UniProtKB:O95977, Asn-64, MOD:00684." [IEDB_epitope:2141148, PRO:DNx]


organism-modification



PR:000084347

sphingosine 1-phosphate receptor 4 cysteinylated 1 (human)

hS1PR4/Cyst:1


"A sphingosine 1-phosphate receptor 4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-315 of the amino acid sequence represented by UniProtKB:O95977. UniProtKB:O95977, Cys-315, MOD:00765." [IEDB_epitope:1582571, PRO:DNx]


organism-gene



PR:Q9Z0L1

sphingosine 1-phosphate receptor 4 (mouse)

mS1PR4


"A sphingosine 1-phosphate receptor 4 that is encoded in the genome of mouse." [OMA:Q9Z0L1, PRO:DNx]


gene



PR:000001710

sphingosine 1-phosphate receptor 5

S1PR5


"A lysophospholipid (S1P) receptor that is a translation product of the human S1PR5 gene or a 1:1 ortholog thereof. Although widely expressed in the brain, most prominently in the corpus callosum, it is detected at a low level in most tissues." [PRO:WCB, UniProtKB:Q9H228]


organism-gene



PR:Q91X56

sphingosine 1-phosphate receptor 5 (mouse)

mS1PR5


"A sphingosine 1-phosphate receptor 5 that is encoded in the genome of mouse." [OMA:Q91X56, PRO:DNx]


organism-sequence



PR:Q91X56-1

sphingosine 1-phosphate receptor 5 isoform 1 (mouse)

mS1PR5/iso:1


"A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q9H228

sphingosine 1-phosphate receptor 5 (human)

hS1PR5


"A sphingosine 1-phosphate receptor 5 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9H228]


organism-sequence



PR:Q9H228-1

sphingosine 1-phosphate receptor 5 isoform h1 (human)

hS1PR5/iso:h1


"A sphingosine 1-phosphate receptor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H228-1." [PRO:DNx, UniProtKB:Q9H228]


organism-sequence



PR:Q9H228-2

sphingosine 1-phosphate receptor 5 isoform h2 (human)

hS1PR5/iso:h2


"A sphingosine 1-phosphate receptor 5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H228-2." [PRO:DNx, UniProtKB:Q9H228]


organism-modification



PR:000066925

sphingosine 1-phosphate receptor 5 phosphorylated 1 (human)

hS1PR5/Phos:1


"A sphingosine 1-phosphate receptor 5 (human) that has been phosphorylated on the residue at the position equivalent to Ser-246 of the amino acid sequence represented by UniProtKB:Q9H228-1. Example: UniProtKB:Q9H228-1, Ser-246, MOD:00046." [IEDB_epitope:912348, PRO:DNx]


organism-gene



PR:Q9JKM5

sphingosine 1-phosphate receptor 5 (rat)

rS1PR5


"A sphingosine 1-phosphate receptor 5 that is encoded in the genome of rat." [OMA:Q9JKM5, PRO:DNx]


organism-sequence



PR:Q9JKM5-1

sphingosine 1-phosphate receptor 5 isoform 1 (rat)

rS1PR5/iso:1


"A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


sequence



PR:000042251

sphingosine 1-phosphate receptor 5 isoform 1

S1PR5/iso:1


"A sphingosine 1-phosphate receptor 5 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91X56-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:Q91X56-1

sphingosine 1-phosphate receptor 5 isoform 1 (mouse)

mS1PR5/iso:1


"A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q9JKM5-1

sphingosine 1-phosphate receptor 5 isoform 1 (rat)

rS1PR5/iso:1


"A sphingosine 1-phosphate receptor 5 isoform 1 that is encoded in the genome of rat." [PRO:DNx]