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RACE-PRO
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Protein Ontology report - proteinase-activated receptor 2
PR:000001662 -
http://purl.obolibrary.org/obo/PR_000001662
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000001662
PRO name
proteinase-activated receptor 2
Synonyms
PRO-Short-label
:
EXACT:
F2RL1
Gene-based
:
RELATED:
Gpcr11 | GPR11 | PAR2
Other
:
EXACT:
coagulation factor II receptor-like 1 | G-protein coupled receptor 11 | PAR-2 | thrombin receptor-like 1
Definition
"A proteinase-activated receptor that is a translation product of the human F2RL1 gene or a 1:1 ortholog thereof. It is activated by trypsin and trypsin-like proteinases, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." [
PMID:7556175
, PRO:WCB]
PRO Category
gene
Parent
PR:000001550
proteinase-activated receptor
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
1
Organism-Gene
3
Sequence
0
Organism-Sequence
0
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
IUPHARobj:348
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
gene
PR:000001662
proteinase-activated receptor 2
F2RL1
"A proteinase-activated receptor that is a translation product of the human F2RL1 gene or a 1:1 ortholog thereof. It is activated by trypsin and trypsin-like proteinases, which cleave the mature peptide, exposing a new amino end. The six new N-terminal residues act as a tethered ligand that induces activity." [PMID:7556175, PRO:WCB]
organism-gene
PR:P55085
proteinase-activated receptor 2 (human)
hF2RL1
"A proteinase-activated receptor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P55085]
organism-gene
PR:P55086
proteinase-activated receptor 2 (mouse)
mF2RL1
"A proteinase-activated receptor 2 that is encoded in the genome of mouse." [OMA:P55086, PRO:DNx]
organism-gene
PR:Q63645
proteinase-activated receptor 2 (rat)
rF2RL1
"A proteinase-activated receptor 2 that is encoded in the genome of rat." [OMA:Q63645, PRO:DNx]
