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Protein Ontology report - prostaglandin E2 receptor EP3 subtype
PR:000001659 - http://purl.obolibrary.org/obo/PR_000001659
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001659   
  PRO nameprostaglandin E2 receptor EP3 subtype 
  Synonyms
PRO-Short-label: EXACT:PTGER3
Gene-based: RELATED:Ptgerep3
Other: EXACT:PGE receptor EP3 subtype | PGE2 receptor EP3 subtype | PGE2-R | prostaglandin E2 receptor EP3 | prostanoid EP3 receptor
  Definition"A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney." [PMID:7938166, PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001549 prostanoid receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 18                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:342
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001659
prostaglandin E2 receptor EP3 subtype
PTGER3
"A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney." [PMID:7938166, PRO:WCB]

organism-gene


PR:P30557
prostaglandin E2 receptor EP3 subtype (mouse)
mPTGER3
"A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of mouse." [OMA:P30557, PRO:DNx]

organism-sequence


PR:P30557-1
prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)
mPTGER3/iso:Alpha
"A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
Yes
organism-sequence


PR:P30557-2
prostaglandin E2 receptor EP3 subtype isoform Beta (mouse)
mPTGER3/iso:Beta
"A prostaglandin E2 receptor EP3 subtype isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P30557-3
prostaglandin E2 receptor EP3 subtype isoform Gamma (mouse)
mPTGER3/iso:Gamma
"A prostaglandin E2 receptor EP3 subtype isoform 3 that is encoded in the genome of mouse." [PRO:DNx]

organism-gene


PR:P34980
prostaglandin E2 receptor EP3 subtype (rat)
rPTGER3
"A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of rat." [OMA:P34980, PRO:DNx]

organism-sequence


PR:P34980-1
prostaglandin E2 receptor EP3 subtype isoform Alpha (rat)
rPTGER3/iso:Alpha
"A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:P34980-2
prostaglandin E2 receptor EP3 subtype isoform Beta (rat)
rPTGER3/iso:Beta
"A prostaglandin E2 receptor EP3 subtype isoform 2 that is encoded in the genome of rat." [PRO:DNx]

organism-sequence


PR:P34980-3
prostaglandin E2 receptor EP3 subtype isoform Gamma (rat)
rPTGER3/iso:Gamma
"A prostaglandin E2 receptor EP3 subtype isoform 3 that is encoded in the genome of rat." [PRO:DNx]

organism-gene


PR:P43115
prostaglandin E2 receptor EP3 subtype (human)
hPTGER3
"A prostaglandin E2 receptor EP3 subtype that is encoded in the genome of human." [PRO:WCB, UniProtKB:P43115]

organism-sequence


PR:P43115-1
prostaglandin E2 receptor EP3 subtype isoform hEP3A (human)
hPTGER3/iso:hEP3A
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-1." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-10
prostaglandin E2 receptor EP3 subtype isoform hEP3-V (human)
hPTGER3/iso:hEP3-V
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-10." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-11
prostaglandin E2 receptor EP3 subtype isoform hEP3E2 (human)
hPTGER3/iso:hEP3E2
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-11." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-12
prostaglandin E2 receptor EP3 subtype isoform h12 (human)
hPTGER3/iso:h12
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-12." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-2
prostaglandin E2 receptor EP3 subtype isoform hEP3C (human)
hPTGER3/iso:hEP3C
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-2." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-3
prostaglandin E2 receptor EP3 subtype isoform hEP3B (human)
hPTGER3/iso:hEP3B
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-3." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-4
prostaglandin E2 receptor EP3 subtype isoform hEP3D (human)
hPTGER3/iso:hEP3D
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-4." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-5
prostaglandin E2 receptor EP3 subtype isoform hEP3E (human)
hPTGER3/iso:hEP3E
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-5." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-6
prostaglandin E2 receptor EP3 subtype isoform hEP3F (human)
hPTGER3/iso:hEP3F
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-6." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-7
prostaglandin E2 receptor EP3 subtype isoform hEP3G (human)
hPTGER3/iso:hEP3G
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-7." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-8
prostaglandin E2 receptor EP3 subtype isoform hEP3-III (human)
hPTGER3/iso:hEP3-III
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-8." [PRO:DNx, UniProtKB:P43115]

organism-sequence


PR:P43115-9
prostaglandin E2 receptor EP3 subtype isoform hEP3-IV (human)
hPTGER3/iso:hEP3-IV
"A prostaglandin E2 receptor EP3 subtype (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43115-9." [PRO:DNx, UniProtKB:P43115]

sequence


PR:000039252
prostaglandin E2 receptor EP3 subtype isoform 1
PTGER3/iso:1
"A prostaglandin E2 receptor EP3 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30557-1 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P30557-1
prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)
mPTGER3/iso:Alpha
"A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
Yes
organism-sequence


PR:P34980-1
prostaglandin E2 receptor EP3 subtype isoform Alpha (rat)
rPTGER3/iso:Alpha
"A prostaglandin E2 receptor EP3 subtype isoform 1 that is encoded in the genome of rat." [PRO:DNx]

sequence


PR:000039253
prostaglandin E2 receptor EP3 subtype isoform 2
PTGER3/iso:2
"A prostaglandin E2 receptor EP3 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30557-2 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P30557-2
prostaglandin E2 receptor EP3 subtype isoform Beta (mouse)
mPTGER3/iso:Beta
"A prostaglandin E2 receptor EP3 subtype isoform 2 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P34980-2
prostaglandin E2 receptor EP3 subtype isoform Beta (rat)
rPTGER3/iso:Beta
"A prostaglandin E2 receptor EP3 subtype isoform 2 that is encoded in the genome of rat." [PRO:DNx]

sequence


PR:000039254
prostaglandin E2 receptor EP3 subtype isoform 3
PTGER3/iso:3
"A prostaglandin E2 receptor EP3 subtype that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30557-3 or a 1:1 ortholog thereof." [PRO:DNx]

organism-sequence


PR:P30557-3
prostaglandin E2 receptor EP3 subtype isoform Gamma (mouse)
mPTGER3/iso:Gamma
"A prostaglandin E2 receptor EP3 subtype isoform 3 that is encoded in the genome of mouse." [PRO:DNx]

organism-sequence


PR:P34980-3
prostaglandin E2 receptor EP3 subtype isoform Gamma (rat)
rPTGER3/iso:Gamma
"A prostaglandin E2 receptor EP3 subtype isoform 3 that is encoded in the genome of rat." [PRO:DNx]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P30557-1 mPTGER3/iso:Alpha enablesGO:0004957 prostaglandin E receptor activity MGI_ref:64071; PMID:8381413