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Protein Ontology report - prostaglandin E2 receptor EP3 subtype
PR:000001659 - http://purl.obolibrary.org/obo/PR_000001659
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001659   
  PRO nameprostaglandin E2 receptor EP3 subtype 
  Synonyms
PRO-Short-label: EXACT:PTGER3
Gene-based: RELATED:Ptgerep3
Other: EXACT:PGE receptor EP3 subtype | PGE2 receptor EP3 subtype | PGE2-R | prostaglandin E2 receptor EP3 | prostanoid EP3 receptor
  Definition"A prostanoid receptor that is a translation product of the human PTGER3 gene or a 1:1 ortholog thereof. The preferred ligand is prostaglandin E2 (PGE2). This receptor is the most ubiquitous of the prostaglandin E2 receptors, mediating contraction of gastrointestinal, uterine, and vascular smooth muscle, inhibition of neurotransmitter release from autonomic nerves, inhibition of lipolysis in adipocytes, inhibition of acid secretion from gastric mucosa, and inhibition of water reabsorption in kidney." [PMID:7938166, PRO:WCB] 
  PRO Categorygene 
  ParentPR:000001549 prostanoid receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 18                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:342
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001659 prostaglandin E2 receptor EP3 subtype
PTGER3

organism-gene


PR:P30557 prostaglandin E2 receptor EP3 subtype (mouse)
mPTGER3

organism-sequence


PR:P30557-1 prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)
mPTGER3/iso:Alpha
Yes
organism-sequence


PR:P30557-2 prostaglandin E2 receptor EP3 subtype isoform Beta (mouse)
mPTGER3/iso:Beta

organism-sequence


PR:P30557-3 prostaglandin E2 receptor EP3 subtype isoform Gamma (mouse)
mPTGER3/iso:Gamma

organism-gene


PR:P34980 prostaglandin E2 receptor EP3 subtype (rat)
rPTGER3

organism-sequence


PR:P34980-1 prostaglandin E2 receptor EP3 subtype isoform Alpha (rat)
rPTGER3/iso:Alpha

organism-sequence


PR:P34980-2 prostaglandin E2 receptor EP3 subtype isoform Beta (rat)
rPTGER3/iso:Beta

organism-sequence


PR:P34980-3 prostaglandin E2 receptor EP3 subtype isoform Gamma (rat)
rPTGER3/iso:Gamma

organism-gene


PR:P43115 prostaglandin E2 receptor EP3 subtype (human)
hPTGER3

organism-sequence


PR:P43115-1 prostaglandin E2 receptor EP3 subtype isoform hEP3A (human)
hPTGER3/iso:hEP3A

organism-sequence


PR:P43115-10 prostaglandin E2 receptor EP3 subtype isoform hEP3-V (human)
hPTGER3/iso:hEP3-V

organism-sequence


PR:P43115-11 prostaglandin E2 receptor EP3 subtype isoform hEP3E2 (human)
hPTGER3/iso:hEP3E2

organism-sequence


PR:P43115-12 prostaglandin E2 receptor EP3 subtype isoform h12 (human)
hPTGER3/iso:h12

organism-sequence


PR:P43115-2 prostaglandin E2 receptor EP3 subtype isoform hEP3C (human)
hPTGER3/iso:hEP3C

organism-sequence


PR:P43115-3 prostaglandin E2 receptor EP3 subtype isoform hEP3B (human)
hPTGER3/iso:hEP3B

organism-sequence


PR:P43115-4 prostaglandin E2 receptor EP3 subtype isoform hEP3D (human)
hPTGER3/iso:hEP3D

organism-sequence


PR:P43115-5 prostaglandin E2 receptor EP3 subtype isoform hEP3E (human)
hPTGER3/iso:hEP3E

organism-sequence


PR:P43115-6 prostaglandin E2 receptor EP3 subtype isoform hEP3F (human)
hPTGER3/iso:hEP3F

organism-sequence


PR:P43115-7 prostaglandin E2 receptor EP3 subtype isoform hEP3G (human)
hPTGER3/iso:hEP3G

organism-sequence


PR:P43115-8 prostaglandin E2 receptor EP3 subtype isoform hEP3-III (human)
hPTGER3/iso:hEP3-III

organism-sequence


PR:P43115-9 prostaglandin E2 receptor EP3 subtype isoform hEP3-IV (human)
hPTGER3/iso:hEP3-IV

sequence


PR:000039252 prostaglandin E2 receptor EP3 subtype isoform 1
PTGER3/iso:1

organism-sequence


PR:P30557-1 prostaglandin E2 receptor EP3 subtype isoform Alpha (mouse)
mPTGER3/iso:Alpha
Yes
organism-sequence


PR:P34980-1 prostaglandin E2 receptor EP3 subtype isoform Alpha (rat)
rPTGER3/iso:Alpha

sequence


PR:000039253 prostaglandin E2 receptor EP3 subtype isoform 2
PTGER3/iso:2

organism-sequence


PR:P30557-2 prostaglandin E2 receptor EP3 subtype isoform Beta (mouse)
mPTGER3/iso:Beta

organism-sequence


PR:P34980-2 prostaglandin E2 receptor EP3 subtype isoform Beta (rat)
rPTGER3/iso:Beta

sequence


PR:000039254 prostaglandin E2 receptor EP3 subtype isoform 3
PTGER3/iso:3

organism-sequence


PR:P30557-3 prostaglandin E2 receptor EP3 subtype isoform Gamma (mouse)
mPTGER3/iso:Gamma

organism-sequence


PR:P34980-3 prostaglandin E2 receptor EP3 subtype isoform Gamma (rat)
rPTGER3/iso:Gamma

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P30557-1 mPTGER3/iso:Alpha enablesGO:0004957 prostaglandin E receptor activity MGI_ref:64071; PMID:8381413