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Protein Ontology report - glycoprotein hormone receptor
PR:000001463 - http://purl.obolibrary.org/obo/PR_000001463
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001463   
  PRO nameglycoprotein hormone receptor 
  Definition"A rhodopsin-like G-protein coupled receptor that is a translation product of the human FSHR, LHCGR, or TSHR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds glycoprotein hormones (thyrotropin, follitropin, lutropin, choriogonadotropin)." [PRO:WCB, PRO:XQ] 
  PRO Categoryfamily 
  ParentPR:000001094 rhodopsin-like G-protein coupled receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 12                                        
         Sequence3                                                  Organism-Sequence 26                                        
         Modification2                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF002408;IUPHARfam:30
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001463

glycoprotein hormone receptor

GYPC


"A rhodopsin-like G-protein coupled receptor that is a translation product of the human FSHR, LHCGR, or TSHR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds glycoprotein hormones (thyrotropin, follitropin, lutropin, choriogonadotropin)." [PRO:WCB, PRO:XQ]


gene



PR:000001581

follitropin receptor

FSHR


"A glycoprotein hormone receptor that is a translation product of the human FSHR gene or a 1:1 ortholog thereof. The preferred ligand is follitropin (follicle-stimulating hormone)." [PRO:WCB]


organism-gene



PR:P20395

follicle-stimulating hormone receptor (rat)

rFSHR


"A follitropin receptor that is encoded in the genome of rat." [OMA:P20395, PRO:DNx]


organism-sequence



PR:P20395-1

follicle-stimulating hormone receptor isoform 1 (rat)

rFSHR/iso:1


"A follitropin receptor isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P23945

follicle-stimulating hormone receptor (human)

hFSHR


"A follitropin receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P23945]


organism-sequence



PR:P23945-1

follicle-stimulating hormone receptor isoform Long (human)

hFSHR/iso:Long


"A follicle-stimulating hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23945-1." [PRO:DNx, UniProtKB:P23945]


organism-sequence



PR:P23945-2

follicle-stimulating hormone receptor isoform Short (human)

hFSHR/iso:Short


"A follicle-stimulating hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23945-2." [PRO:DNx, UniProtKB:P23945]


organism-sequence



PR:P23945-3

follicle-stimulating hormone receptor isoform h3 (human)

hFSHR/iso:h3


"A follicle-stimulating hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23945-3." [PRO:DNx, UniProtKB:P23945]


organism-sequence



PR:P23945-4

follicle-stimulating hormone receptor isoform h4 (human)

hFSHR/iso:h4


"A follicle-stimulating hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23945-4." [PRO:DNx, UniProtKB:P23945]


organism-modification



PR:000026866

follitropin receptor, signal peptide removed form (human)

hFSHR/SigPep-


"A follitropin receptor, signal peptide removed form in human. Example: UniProtKB:P23945-1, 18-695." [PRO:CNA, Reactome:R-HSA-391380]


organism-modification



PR:000068999

follicle-stimulating hormone receptor deaminated 1 (human)

hFSHR/Deam:1


"A follicle-stimulating hormone receptor (human) that has been deaminated on the residue at the position equivalent to Asn-93 of the amino acid sequence represented by UniProtKB:P23945-1. Example: UniProtKB:P23945-1, Asn-93, MOD:00684." [IEDB_epitope:929352, PRO:DNx]


organism-modification



PR:000075711

follicle-stimulating hormone receptor cysteinylated 1 (human)

hFSHR/Cyst:1


"A follicle-stimulating hormone receptor (human) that has been cysteinylated on the residue at the position equivalent to Cys-410 of the amino acid sequence represented by UniProtKB:P23945-1. Example: UniProtKB:P23945-1, Cys-410, MOD:00765." [IEDB_epitope:1855322, PRO:DNx]


organism-gene



PR:P35378

follicle-stimulating hormone receptor (mouse)

mFSHR


"A follitropin receptor that is encoded in the genome of mouse." [OMA:P35378, PRO:WCB]


organism-sequence



PR:P35378-1

follicle-stimulating hormone receptor isoform 1 (mouse)

mFSHR/iso:1


"A follitropin receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P79763

follicle-stimulating hormone receptor (chicken)

chick-FSHR


"A follitropin receptor that is encoded in the genome of chicken." [PRO:WCB]


sequence



PR:000039335

follitropin receptor isoform 1

FSHR/iso:1


"A follitropin receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35378-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P20395-1

follicle-stimulating hormone receptor isoform 1 (rat)

rFSHR/iso:1


"A follitropin receptor isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P35378-1

follicle-stimulating hormone receptor isoform 1 (mouse)

mFSHR/iso:1


"A follitropin receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000026865

follitropin receptor, signal peptide removed form

FSHR/SigPep-


"A follitropin receptor that has had the signal peptide removed. Example: UniProtKB:P23945-1, 18-695." [PRO:CNx, Reactome:R-HSA-391380]


organism-modification



PR:000026866

follitropin receptor, signal peptide removed form (human)

hFSHR/SigPep-


"A follitropin receptor, signal peptide removed form in human. Example: UniProtKB:P23945-1, 18-695." [PRO:CNA, Reactome:R-HSA-391380]


gene



PR:000001596

lutropin-choriogonadotropic hormone receptor

LHCGR


"A glycoprotein hormone receptor that is a translation product of the human LHCGR gene or a 1:1 ortholog thereof. The preferred ligands are lutropin (luteinizing hormone) and choriogonadotropin (choriogonadotropic hormone)." [PRO:WCB]


organism-gene



PR:P16235

lutropin-choriogonadotropic hormone receptor (rat)

rLHCGR


"A lutropin-choriogonadotropic hormone receptor that is encoded in the genome of rat." [OMA:P16235, PRO:DNx]


organism-sequence



PR:P16235-1

lutropin-choriogonadotropic hormone receptor isoform 1 (rat)

rLHCGR/iso:1


"A lutropin-choriogonadotropic hormone receptor isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P16235-10

lutropin-choriogonadotropic hormone receptor isoform rB1 (rat)

rLHCGR/iso:rB1


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-10." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-11

lutropin-choriogonadotropic hormone receptor isoform rB3 (rat)

rLHCGR/iso:rB3


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-11." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-2

lutropin-choriogonadotropic hormone receptor isoform r1759 (rat)

rLHCGR/iso:r1759


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-2." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-3

lutropin-choriogonadotropic hormone receptor isoform r1834 (rat)

rLHCGR/iso:r1834


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-3." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-4

lutropin-choriogonadotropic hormone receptor isoform r1950 (rat)

rLHCGR/iso:r1950


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-4." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-5

lutropin-choriogonadotropic hormone receptor isoform r2075 (rat)

rLHCGR/iso:r2075


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-5." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-6

lutropin-choriogonadotropic hormone receptor isoform rC1 (rat)

rLHCGR/iso:rC1


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-6." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-7

lutropin-choriogonadotropic hormone receptor isoform rC2 (rat)

rLHCGR/iso:rC2


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-7." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-8

lutropin-choriogonadotropic hormone receptor isoform rEA2 (rat)

rLHCGR/iso:rEA2


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-8." [PRO:DNx, UniProtKB:P16235]


organism-sequence



PR:P16235-9

lutropin-choriogonadotropic hormone receptor isoform EB (rat)

rLHCGR/iso:EB


"A lutropin-choriogonadotropic hormone receptor (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16235-9." [PRO:DNx, UniProtKB:P16235]


organism-gene



PR:P22888

lutropin-choriogonadotropic hormone receptor (human)

hLHCGR


"A lutropin-choriogonadotropic hormone receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P22888]


organism-sequence



PR:P22888-1

lutropin-choriogonadotropic hormone receptor isoform Long (human)

hLHCGR/iso:Long


"A lutropin-choriogonadotropic hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22888-1." [PRO:DNx, UniProtKB:P22888]


organism-sequence



PR:P22888-2

lutropin-choriogonadotropic hormone receptor isoform Short (human)

hLHCGR/iso:Short


"A lutropin-choriogonadotropic hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22888-2." [PRO:DNx, UniProtKB:P22888]


organism-modification



PR:000048196

lutropin-choriogonadotropic hormone receptor, signal peptide removed form (human)

hLHCGR/SigPep-


"A lutropin-choriogonadotropic hormone receptor (human) that has had the signal peptide removed. UniProtKB:P22888, 27-699." [PRO:DNx, Reactome:R-HSA-391366]


organism-gene



PR:P30730

lutropin-choriogonadotropic hormone receptor (mouse)

mLHCGR


"A lutropin-choriogonadotropic hormone receptor that is encoded in the genome of mouse." [OMA:P30730, PRO:DNx]


organism-sequence



PR:P30730-1

lutropin-choriogonadotropic hormone receptor isoform 1 (mouse)

mLHCGR/iso:1


"A lutropin-choriogonadotropic hormone receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q90674

lutropin-choriogonadotropic hormone receptor (chicken)

chick-LHCGR


"A lutropin-choriogonadotropic hormone receptor that is encoded in the genome of chicken." [OMA:Q90674, PRO:DNx]


organism-sequence



PR:Q90674-1

lutropin-choriogonadotropic hormone receptor isoform 1 (chicken)

chick-LHCGR/iso:1


"A lutropin-choriogonadotropic hormone receptor (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q90674-1." [PRO:DNx, UniProtKB:Q90674]


organism-sequence



PR:Q90674-2

lutropin-choriogonadotropic hormone receptor isoform 2 (chicken)

chick-LHCGR/iso:2


"A lutropin-choriogonadotropic hormone receptor (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q90674-2." [PRO:DNx, UniProtKB:Q90674]


sequence



PR:000039261

lutropin-choriogonadotropic hormone receptor isoform 1

LHCGR/iso:1


"A lutropin-choriogonadotropic hormone receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P30730-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P16235-1

lutropin-choriogonadotropic hormone receptor isoform 1 (rat)

rLHCGR/iso:1


"A lutropin-choriogonadotropic hormone receptor isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P30730-1

lutropin-choriogonadotropic hormone receptor isoform 1 (mouse)

mLHCGR/iso:1


"A lutropin-choriogonadotropic hormone receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000001677

thyrotropin receptor

TSHR


"A glycoprotein hormone receptor that is a translation product of the human TSHR gene or a 1:1 ortholog thereof. The preferred ligand is thyrotropin (thyroid-stimulating hormone)." [PRO:WCB]


organism-gene



PR:F1NKT4

thyrotropin receptor (chicken)

chick-TSHR


"A thyrotropin receptor that is encoded in the genome of chicken." [OMA:F1NKT4, PRO:DNx]


organism-gene



PR:P16473

thyrotropin receptor (human)

hTSHR


"A thyrotropin receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P16473]


organism-sequence



PR:P16473-1

thyrotropin receptor isoform Long (human)

hTSHR/iso:Long


"A thyrotropin receptor isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P16473-2

thyrotropin receptor isoform Short (human)

hTSHR/iso:Short


"A thyrotropin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16473-2." [PRO:DNx, UniProtKB:P16473]


organism-sequence



PR:P16473-3

thyrotropin receptor isoform h3 (human)

hTSHR/iso:h3


"A thyrotropin receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16473-3." [PRO:DNx, UniProtKB:P16473]


organism-modification



PR:000049558

thyrotropin receptor, signal peptide removed form (human)

hTSHR/SigPep-


"A thyrotropin receptor (human) that has had the signal peptide removed. UniProtKB:P16473, 21-764." [PRO:DNx, Reactome:R-HSA-391371]


organism-gene



PR:P21463

thyrotropin receptor (rat)

rTSHR


"A thyrotropin receptor that is encoded in the genome of rat." [OMA:P21463, PRO:DNx]


organism-gene



PR:P47750

thyrotropin receptor (mouse)

mTSHR


"A thyrotropin receptor that is encoded in the genome of mouse." [OMA:P47750, PRO:DNx]


organism-sequence



PR:P47750-1

thyrotropin receptor isoform 1 (mouse)

mTSHR/iso:1


"A thyrotropin receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038957

thyrotropin receptor isoform 1

TSHR/iso:1


"A thyrotropin receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16473-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P16473-1

thyrotropin receptor isoform Long (human)

hTSHR/iso:Long


"A thyrotropin receptor isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P47750-1

thyrotropin receptor isoform 1 (mouse)

mTSHR/iso:1


"A thyrotropin receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000018515

thyrotropin receptor, signal peptide removed form

TSHR/SigPep-


"A thyrotropin receptor that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000049558

thyrotropin receptor, signal peptide removed form (human)

hTSHR/SigPep-


"A thyrotropin receptor (human) that has had the signal peptide removed. UniProtKB:P16473, 21-764." [PRO:DNx, Reactome:R-HSA-391371]