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Protein Ontology report - interleukin-2
PR:000001379 - http://purl.obolibrary.org/obo/PR_000001379
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001379   
  PRO nameinterleukin-2 
  Synonyms
PRO-Short-label: EXACT:IL2
Other: EXACT:aldesleukin | IL-2 | T-cell growth factor | TCGF
  Definition"A protein that is a translation product of the human IL2 gene or a 1:1 ortholog thereof. Interleukin-2 has a dual role in maintaining tolerance and contributing to immunity." [PMID:18062768, PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF001938
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001379

interleukin-2

IL2


"A protein that is a translation product of the human IL2 gene or a 1:1 ortholog thereof. Interleukin-2 has a dual role in maintaining tolerance and contributing to immunity." [PMID:18062768, PRO:CNA]


organism-gene



PR:P04351

interleukin-2 (mouse)

mIL2


"An interleukin-2 that is encoded in the genome of mouse." [OMA:P04351, PRO:DNx]


organism-gene



PR:P17108

interleukin-2 (rat)

rIL2


"An interleukin-2 that is encoded in the genome of rat." [OMA:P17108, PRO:DNx]


organism-gene



PR:P60568

interleukin-2 (human)

hIL2


"An interleukin-2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P60568]


organism-modification



PR:000048003

interleukin-2, signal peptide removed form (human)

hIL2/SigPep-


"An interleukin-2 (human) that has had the signal peptide removed. UniProtKB:P60568, 21-153." [PRO:DNx, Reactome:R-HSA-447099]


organism-modification



PR:000056666

interleukin-2 O-glycosylated 1 (human)

hIL2/OGlyco:1


"An interleukin-2 (human) that has been O-glycosylated at the residue equivalent to Thr-23 of the amino acid sequence represented by UniProtKB:P60568-1, in which the glycan structure is represented by GlyTouCan:G00031MO. Example: UniProtKB:P60568-1, Thr-23, MOD:00005~GNO:G00031MO." [GlyGen:P60568-1, PMID:10861392, PMID:2793860, PMID:3935432, PMID:8344280, PRO:DNx]


organism-modification



PR:000056667

interleukin-2 O-glycosylated 2 (human)

hIL2/OGlyco:2


"An interleukin-2 (human) that has been O-glycosylated at the residue equivalent to Thr-23 of the amino acid sequence represented by UniProtKB:P60568-1, in which the glycan structure is represented by GlyTouCan:G01614ZM. Example: UniProtKB:P60568-1, Thr-23, MOD:00005~GNO:G01614ZM." [GlyGen:P60568-1, PMID:10861392, PMID:2793860, PMID:3935432, PMID:8344280, PRO:DNx]


organism-modification



PR:000056668

interleukin-2 O-glycosylated 3 (human)

hIL2/OGlyco:3


"An interleukin-2 (human) that has been O-glycosylated at the residue equivalent to Thr-23 of the amino acid sequence represented by UniProtKB:P60568-1, in which the glycan structure is represented by GlyTouCan:G65562ZE. Example: UniProtKB:P60568-1, Thr-23, MOD:00005~GNO:G65562ZE." [GlyGen:P60568-1, PMID:10861392, PMID:2793860, PMID:3935432, PMID:8344280, PRO:DNx]


modification



PR:000018442

interleukin-2, signal peptide removed form

IL2/SigPep-


"An interleukin-2 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000048003

interleukin-2, signal peptide removed form (human)

hIL2/SigPep-


"An interleukin-2 (human) that has had the signal peptide removed. UniProtKB:P60568, 21-153." [PRO:DNx, Reactome:R-HSA-447099]