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Protein Ontology report - interferon lambda
PR:000001362 - http://purl.obolibrary.org/obo/PR_000001362
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001362   
  PRO nameinterferon lambda 
  Synonyms
Other: RELATED:interferon type III | type III interferon
  Definition"A type III interferon that is distantly related to type I interferons (IFNs) and the interleukin-10 family. It comprises the translation product of the IL28A, IL28B and IL29 genes. Generally induced by viral infection and exert their antiviral and immunomodulatory activities through a unique receptor complex composed of IFN-lambdaR1 and interleukin 10 receptor 2." [PMID:16618774] 
  CommentNote: Some references consider 'lambda' and 'type III' to be synonyms. This is likely because lambda is the only type III interferon identified. However, the classification criteria for each nomenclature system differ. 
  PRO Categoryfamily 
  ParentPR:000028205 type III interferon
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001362 interferon lambda
IFNGR1

gene


PR:000001469 interleukin-28A
IFNL2

organism-gene


PR:Q8IZJ0 interferon lambda-2 (human)
hIFNL2

organism-modification


PR:000047967 interferon lambda-2, signal peptide removed form (human)
hIFNL2/SigPep-

gene


PR:000001470 interleukin-28B
IFNL3

organism-gene


PR:B4ER10 interferon lambda-3 (chicken)
chick-IFNL3

organism-gene


PR:Q8IZI9 interferon lambda-3 (human)
hIFNL3

organism-modification


PR:000047968 interferon lambda-3, signal peptide removed form (human)
hIFNL3/SigPep-

gene


PR:000001476 interleukin-29
IFNL1

organism-gene


PR:Q8IU54 interferon lambda-1 (human)
hIFNL1

organism-modification


PR:000047966 interferon lambda-1, signal peptide removed form (human)
hIFNL1/SigPep-