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Protein Ontology report - granulocyte-macrophage colony-stimulating factor receptor subunit alpha
PR:000001354 - http://purl.obolibrary.org/obo/PR_000001354
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001354   
  PRO namegranulocyte-macrophage colony-stimulating factor receptor subunit alpha 
  Synonyms
PRO-Short-label: EXACT:CSF2RA
Gene-based: RELATED:CSF2R | CSF2RY | Csfgmra
Other: EXACT:CD116 | CDw116 | GM-CSF-R-alpha | GMCSFR-alpha | GMR-alpha
  Definition"A protein that is a translation product of the human CSF2RA gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 11                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1707
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001354

granulocyte-macrophage colony-stimulating factor receptor subunit alpha

CSF2RA


"A protein that is a translation product of the human CSF2RA gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:P15509

granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human)

hCSF2RA


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha that is encoded in the genome of human." [PRO:CNA, UniProtKB:P15509]


organism-sequence



PR:P15509-1

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h1 (human)

hCSF2RA/iso:h1


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-1." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-2

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h2 (human)

hCSF2RA/iso:h2


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-2." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-3

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h3 (human)

hCSF2RA/iso:h3


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-3." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-4

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h4 (human)

hCSF2RA/iso:h4


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-4." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-5

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h5 (human)

hCSF2RA/iso:h5


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-5." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-6

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h6 (human)

hCSF2RA/iso:h6


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-6." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-7

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h7 (human)

hCSF2RA/iso:h7


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-7." [PRO:DNx, UniProtKB:P15509]


organism-sequence



PR:P15509-8

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform h8 (human)

hCSF2RA/iso:h8


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15509-8." [PRO:DNx, UniProtKB:P15509]


organism-modification



PR:000047081

granulocyte-macrophage colony-stimulating factor receptor subunit alpha, signal peptide removed form (human)

hCSF2RA/SigPep-


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P15509, 23-400." [PRO:DNx, Reactome:R-HSA-913361]


organism-modification



PR:000061132

granulocyte-macrophage colony-stimulating factor receptor subunit alpha sequence variant T174R, signal peptide removed form (human)

hCSF2RA/var:T174R/SigPep-


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that has an Arg residue at the position equivalent to Thr-174 of the amino acid sequence represented by UniProtKB:P15509-1 and that has had the signal peptide removed. Example: UniProtKB:P15509-1, 23-400, Thr-174, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5688867]


organism-gene



PR:Q00941

granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse)

mCSF2RA


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha that is encoded in the genome of mouse." [OMA:Q00941, PRO:DNx]


organism-sequence



PR:A9P557

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 2 (mouse)

mCSF2RA/iso:2


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A9P557. This isoform lacks part of the Fibronectin type-III (PS50853) domain." [GenBank:EF114317, GenPept:ABO38428, PMID:17694571, PRO:HJD]

Yes

organism-sequence



PR:A9P558

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 3 (mouse)

mCSF2RA/iso:3


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A9P558. This isoform lacks the Fibronectin type-III (PS50853) domain and the region coding for the transmembrane domain." [GenBank:EF114318, GenPept:ABO38429, PMID:17694571, PRO:HJD]

Yes

organism-sequence



PR:Q00941-1

granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform 1 (mouse)

mCSF2RA/iso:1


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00941-1." [PMID:1533931, PRO:HJD]

Yes

modification



PR:000018424

granulocyte-macrophage colony-stimulating factor receptor subunit alpha, signal peptide removed form

CSF2RA/SigPep-


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000047081

granulocyte-macrophage colony-stimulating factor receptor subunit alpha, signal peptide removed form (human)

hCSF2RA/SigPep-


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that has had the signal peptide removed. UniProtKB:P15509, 23-400." [PRO:DNx, Reactome:R-HSA-913361]


organism-modification



PR:000061132

granulocyte-macrophage colony-stimulating factor receptor subunit alpha sequence variant T174R, signal peptide removed form (human)

hCSF2RA/var:T174R/SigPep-


"A granulocyte-macrophage colony-stimulating factor receptor subunit alpha (human) that has an Arg residue at the position equivalent to Thr-174 of the amino acid sequence represented by UniProtKB:P15509-1 and that has had the signal peptide removed. Example: UniProtKB:P15509-1, 23-400, Thr-174, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-5688867]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:A9P557 mCSF2RA/iso:2
This isoform lacks part of the Fibronectin type-III (PS50853) domain
acts_upstream_of_or_withinNOT GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus MGI_ref:3721369; PMID:17694571
PR:A9P558 mCSF2RA/iso:3
This isoform lacks the Fibronectin type-III (PS50853) domain and the region coding for the transmembrane domain
acts_upstream_of_or_withinNOT GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus MGI_ref:3721369; PMID:17694571
PR:Q00941-1 mCSF2RA/iso:1 acts_upstream_of_or_withinGO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus MGI_ref:3721369; PMID:17694571
enablesGO:0004902 granulocyte colony-stimulating factor receptor activity MGI_ref:3721369; PMID:17694571
GO:0051916 granulocyte colony-stimulating factor binding MGI_ref:3721369; PMID:17694571
located_inGO:0005886 plasma membrane MGI_ref:3721369; PMID:17694571