back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - discoidin domain-containing receptor
PR:000001342 - http://purl.obolibrary.org/obo/PR_000001342
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001342   
  PRO namediscoidin domain-containing receptor 
  Definition"A protein that has a core domain structure of an F5/8 type C (Pfam:PF00754) domain (or discoidin domain) followed by a Protein tyrosine kinase (Pfam:PF07714) domain. The discoidin domain receptors (DDRs) are distinguished from other members of the receptor tyrosine kinase family by a discoidin homology repeat in their extracellular domains that is also found in a variety of other transmembrane and secreted proteins." [PMID:10352148, PMID:9684896] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 5                                        
         Sequence0                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF038747
Back to top
Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
family


PR:000001342
discoidin domain-containing receptor
DPP4
"A protein that has a core domain structure of an F5/8 type C (Pfam:PF00754) domain (or discoidin domain) followed by a Protein tyrosine kinase (Pfam:PF07714) domain. The discoidin domain receptors (DDRs) are distinguished from other members of the receptor tyrosine kinase family by a discoidin homology repeat in their extracellular domains that is also found in a variety of other transmembrane and secreted proteins." [PMID:10352148, PMID:9684896]

gene


PR:000001445
discoidin domain-containing receptor 1
DDR1
"A discoidin domain-containing receptor that is a translation product of the human DDR1 gene or a 1:1 ortholog thereof." [PMID:15888913, PRO:CNA]

organism-gene


PR:Q03146
epithelial discoidin domain-containing receptor 1 (mouse)
mDDR1
"A discoidin domain-containing receptor 1 that is encoded in the genome of mouse." [OMA:Q03146, PRO:DNx]

organism-sequence


PR:Q03146-1
epithelial discoidin domain-containing receptor 1 isoform m1 (mouse)
mDDR1/iso:m1
"An epithelial discoidin domain-containing receptor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03146-1." [PRO:DNx, UniProtKB:Q03146]

organism-sequence


PR:Q03146-2
epithelial discoidin domain-containing receptor 1 isoform m2 (mouse)
mDDR1/iso:m2
"An epithelial discoidin domain-containing receptor 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03146-2." [PRO:DNx, UniProtKB:Q03146]

organism-gene


PR:Q08345
epithelial discoidin domain-containing receptor 1 (human)
hDDR1
"A discoidin domain-containing receptor 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q08345]

organism-sequence


PR:Q08345-1
epithelial discoidin domain-containing receptor 1 isoform h1 (human)
hDDR1/iso:h1
"An epithelial discoidin domain-containing receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08345-1." [PRO:DNx, UniProtKB:Q08345]

organism-sequence


PR:Q08345-2
epithelial discoidin domain-containing receptor 1 isoform h2 (human)
hDDR1/iso:h2
"An epithelial discoidin domain-containing receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08345-2." [PRO:DNx, UniProtKB:Q08345]

organism-sequence


PR:Q08345-4
epithelial discoidin domain-containing receptor 1 isoform h3 (human)
hDDR1/iso:h3
"An epithelial discoidin domain-containing receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08345-4." [PRO:DNx, UniProtKB:Q08345]

organism-sequence


PR:Q08345-5
epithelial discoidin domain-containing receptor 1 isoform h4 (human)
hDDR1/iso:h4
"An epithelial discoidin domain-containing receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08345-5." [PRO:DNx, UniProtKB:Q08345]

organism-sequence


PR:Q08345-6
epithelial discoidin domain-containing receptor 1 isoform h5 (human)
hDDR1/iso:h5
"An epithelial discoidin domain-containing receptor 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08345-6." [PRO:DNx, UniProtKB:Q08345]

organism-modification


PR:000047154
epithelial discoidin domain-containing receptor 1, signal peptide removed form (human)
hDDR1/SigPep-
"An epithelial discoidin domain-containing receptor 1 (human) that has had the signal peptide removed. UniProtKB:Q08345, 19-913." [PRO:DNx, Reactome:R-HSA-2327723]

organism-modification


PR:000075552
epithelial discoidin domain-containing receptor 1 citrullinated 1 (human)
hDDR1/Cit:1
"An epithelial discoidin domain-containing receptor 1 (human) that has been citrullinated on the residue at the position equivalent to Arg-862 of the amino acid sequence represented by UniProtKB:Q08345-1. Example: UniProtKB:Q08345-1, Arg-862, MOD:00219." [IEDB_epitope:912398, PRO:DNx]

organism-modification


PR:000078907
epithelial discoidin domain-containing receptor 1 deaminated 1 (human)
hDDR1/Deam:1
"An epithelial discoidin domain-containing receptor 1 (human) that has been deaminated on the residue at the position equivalent to Asn-564 of the amino acid sequence represented by UniProtKB:Q08345-1. Example: UniProtKB:Q08345-1, Asn-564, MOD:00684." [IEDB_epitope:2141282, PRO:DNx]

organism-modification


PR:000079013
epithelial discoidin domain-containing receptor 1 deaminated 2 (human)
hDDR1/Deam:2
"An epithelial discoidin domain-containing receptor 1 (human) that has been deaminated on the residue at the position equivalent to Asn-761 of the amino acid sequence represented by UniProtKB:Q08345-1. Example: UniProtKB:Q08345-1, Asn-761, MOD:00684." [IEDB_epitope:1823370, PRO:DNx]

gene


PR:000001446
discoidin domain-containing receptor 2
DDR2
"A discoidin domain-containing receptor that is a translation product of the human DDR2 gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:Q16832
discoidin domain-containing receptor 2 (human)
hDDR2
"A discoidin domain-containing receptor 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q16832]

organism-modification


PR:000047155
discoidin domain-containing receptor 2, signal peptide removed form (human)
hDDR2/SigPep-
"A discoidin domain-containing receptor 2 (human) that has had the signal peptide removed. UniProtKB:Q16832, 22-855." [PRO:DNx, Reactome:R-HSA-211419]

organism-gene


PR:Q62371
discoidin domain-containing receptor 2 (mouse)
mDDR2
"A discoidin domain-containing receptor 2 that is encoded in the genome of mouse." [OMA:Q62371, PRO:DNx]

organism-gene


PR:Q95ZV7
discoidin domain-containing receptor tyrosine kinase B (worm)
DDR2 (worm)
"A discoidin domain-containing receptor 2 that is encoded in the genome of worm." [PRO:CNA]

organism-sequence


PR:Q95ZV7-1
discoidin domain-containing receptor tyrosine kinase B isoform a (worm)
DDR2/iso:a (worm)
"A discoidin domain-containing receptor tyrosine kinase B (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q95ZV7-1." [PRO:DNx, UniProtKB:Q95ZV7]

organism-sequence


PR:Q95ZV7-2
discoidin domain-containing receptor tyrosine kinase B isoform b (worm)
DDR2/iso:b (worm)
"A discoidin domain-containing receptor tyrosine kinase B (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q95ZV7-2." [PRO:DNx, UniProtKB:Q95ZV7]