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Protein Ontology report - B7-related protein
PR:000001290 - http://purl.obolibrary.org/obo/PR_000001290
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001290   
  PRO nameB7-related protein 
  Definition"A protein that is a member of a family that includes translation products of genes CD86, CD276, ICOSLG, and others. These are membrane-anchored proteins with a small intracellular domain and an extracellular domain with signal sequence, an Immunoglobulin V-set domain (Pfam:PF07686), and a CD80-like C2-set immunoglobulin domain (Pfam:PF08205)." [PRO:WCB] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene6                                                  Organism-Gene 13                                        
         Sequence1                                                  Organism-Sequence 31                                        
         Modification3                                                  Organism-Modification 12                                        
  Term Hierarchy
  Visualization
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001290

B7-related protein

MS4A1


"A protein that is a member of a family that includes translation products of genes CD86, CD276, ICOSLG, and others. These are membrane-anchored proteins with a small intracellular domain and an extracellular domain with signal sequence, an Immunoglobulin V-set domain (Pfam:PF07686), and a CD80-like C2-set immunoglobulin domain (Pfam:PF08205)." [PRO:WCB]


gene



PR:000001411

CD276 molecule

CD276


"A B7-related protein that is a translation product of the human CD276 gene or a 1:1 ortholog thereof. This gene has duplicated in the primate lineage, and the major isoforms expressed have tandemly repeated immunoglobulin-like V and C domains." [PRO:WCB]


organism-gene



PR:Q5ZPR3

CD276 antigen (human)

hCD276


"A CD276 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q5ZPR3]


organism-sequence



PR:Q5ZPR3-1

CD276 antigen isoform h1 (human)

hCD276/iso:h1


"A CD276 antigen (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5ZPR3-1." [PRO:DNx, UniProtKB:Q5ZPR3]


organism-sequence



PR:Q5ZPR3-2

CD276 antigen isoform 2 (human)

hCD276/iso:2


"A CD276 molecule isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q5ZPR3-3

CD276 antigen isoform h3 (human)

hCD276/iso:h3


"A CD276 antigen (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5ZPR3-3." [PRO:DNx, UniProtKB:Q5ZPR3]


organism-sequence



PR:Q5ZPR3-4

CD276 antigen isoform h4 (human)

hCD276/iso:h4


"A CD276 antigen (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5ZPR3-4." [PRO:DNx, UniProtKB:Q5ZPR3]


organism-modification



PR:000067160

CD276 antigen cysteinylated 1 (human)

hCD276/Cyst:1


"A CD276 antigen (human) that has been cysteinylated on the residue at the position equivalent to Cys-122 of the amino acid sequence represented by UniProtKB:Q5ZPR3-1. Example: UniProtKB:Q5ZPR3-1, Cys-122, MOD:00765." [IEDB_epitope:1046413, PRO:DNx]


organism-modification



PR:000075412

CD276 antigen methylated 1 (human)

hCD276/Me:1


"A CD276 antigen (human) that has been methylated on the residue at the position equivalent to Cys-122 of the amino acid sequence represented by UniProtKB:Q5ZPR3-1. Example: UniProtKB:Q5ZPR3-1, Cys-122, MOD:00660." [IEDB_epitope:1046414, PRO:DNx]


organism-gene



PR:Q7TPB4

CD276 antigen (rat)

rCD276


"A CD276 molecule that is encoded in the genome of rat." [PANTHER:PTHR24100:SF49, PRO:DNx]


organism-sequence



PR:Q7TPB4-1

CD276 antigen isoform 1 (rat)

rCD276/iso:1


"A CD276 molecule isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q8VE98

CD276 antigen (mouse)

mCD276


"A CD276 molecule that is encoded in the genome of mouse." [PRO:WCB]


organism-sequence



PR:Q8VE98-1

CD276 antigen isoform 1 (mouse)

mCD276/iso:1


"A CD276 molecule isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000041040

CD276 molecule isoform 2

CD276/iso:2


"A CD276 molecule that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q5ZPR3-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:Q5ZPR3-2

CD276 antigen isoform 2 (human)

hCD276/iso:2


"A CD276 molecule isoform 2 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q7TPB4-1

CD276 antigen isoform 1 (rat)

rCD276/iso:1


"A CD276 molecule isoform 2 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q8VE98-1

CD276 antigen isoform 1 (mouse)

mCD276/iso:1


"A CD276 molecule isoform 2 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000018471

CD276 molecule, signal peptide removed form

CD276/SigPep-


"A CD276 molecule that has had the signal peptide removed." [PRO:DNx]


gene



PR:000001412

CD86 molecule

CD86


"A B7-related protein that is a translation product of the human CD86 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P42081

T-lymphocyte activation antigen CD86 (human)

hCD86


"A CD86 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P42081]


organism-sequence



PR:P42081-1

T-lymphocyte activation antigen CD86 isoform h1 (human)

hCD86/iso:h1


"A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-1." [PRO:DNx, UniProtKB:P42081]


organism-sequence



PR:P42081-2

T-lymphocyte activation antigen CD86 isoform h3 (human)

hCD86/iso:h3


"A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-2." [PRO:DNx, UniProtKB:P42081]


organism-sequence



PR:P42081-3

T-lymphocyte activation antigen CD86 isoform h2 (human)

hCD86/iso:h2


"A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-3." [PRO:DNx, UniProtKB:P42081]


organism-sequence



PR:P42081-4

T-lymphocyte activation antigen CD86 isoform h4 (human)

hCD86/iso:h4


"A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-4." [PRO:DNx, UniProtKB:P42081]


organism-sequence



PR:P42081-5

T-lymphocyte activation antigen CD86 isoform h5 (human)

hCD86/iso:h5


"A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-5." [PRO:DNx, UniProtKB:P42081]


organism-sequence



PR:P42081-6

T-lymphocyte activation antigen CD86 isoform h6 (human)

hCD86/iso:h6


"A T-lymphocyte activation antigen CD86 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42081-6." [PRO:DNx, UniProtKB:P42081]


organism-modification



PR:000046652

T-lymphocyte activation antigen CD86, signal peptide removed form (human)

hCD86/SigPep-


"A T-lymphocyte activation antigen CD86 (human) that has had the signal peptide removed. UniProtKB:P42081, 24-329." [PRO:DNx, Reactome:R-HSA-179784]


organism-gene



PR:P42082

T-lymphocyte activation antigen CD86 (mouse)

mCD86


"A CD86 molecule that is encoded in the genome of mouse." [OMA:P42082, PRO:DNx]


organism-sequence



PR:P42082-1

T-lymphocyte activation antigen CD86 isoform m1 (mouse)

mCD86/iso:m1


"A T-lymphocyte activation antigen CD86 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42082-1." [PRO:DNx, UniProtKB:P42082]


organism-sequence



PR:P42082-2

T-lymphocyte activation antigen CD86 isoform m2 (mouse)

mCD86/iso:m2


"A T-lymphocyte activation antigen CD86 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42082-2." [PRO:DNx, UniProtKB:P42082]


gene



PR:000001425

ICOS ligand

ICOSLG


"A B7-related protein that is a translation product of the human ICOSLG gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:O75144

ICOS ligand (human)

hICOSLG


"An ICOS ligand that is encoded in the genome of human." [PRO:WCB, UniProtKB:O75144]


organism-sequence



PR:O75144-1

ICOS ligand isoform h1 (human)

hICOSLG/iso:h1


"An ICOS ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75144-1." [PRO:DNx, UniProtKB:O75144]


organism-sequence



PR:O75144-2

ICOS ligand isoform h2 (human)

hICOSLG/iso:h2


"An ICOS ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75144-2." [PRO:DNx, UniProtKB:O75144]


organism-sequence



PR:O75144-3

ICOS ligand isoform h3 (human)

hICOSLG/iso:h3


"An ICOS ligand (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75144-3." [PRO:DNx, UniProtKB:O75144]


organism-modification



PR:000047939

ICOS ligand, signal peptide removed form (human)

hICOSLG/SigPep-


"An ICOS ligand (human) that has had the signal peptide removed. UniProtKB:O75144, 19-302." [PRO:DNx, Reactome:R-HSA-197910]


organism-modification



PR:000050819

ICOS ligand N-glycosylated 1 (human)

hICOSLG/NGlyco:1


"An ICOS ligand (human) that has been N-glycosylated at the residue equivalent to Asn-225 of the amino acid sequence represented by UniProtKB:O75144-1, in which the glycan composition is represented by GlyTouCan:G60743GT. Example: UniProtKB:O75144-1, Asn-225, MOD:00160~GNO:G60743GT." [GlyGen:O75144-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000050820

ICOS ligand N-glycosylated 2 (human)

hICOSLG/NGlyco:2


"An ICOS ligand (human) that has been N-glycosylated at the residue equivalent to Asn-225 of the amino acid sequence represented by UniProtKB:O75144-1, in which the glycan composition is represented by GlyTouCan:G87139BK. Example: UniProtKB:O75144-1, Asn-225, MOD:00160~GNO:G87139BK." [GlyGen:O75144-1, PMID:23345538, PRO:DNx]


organism-modification



PR:000082047

ICOS ligand methylated 1 (human)

hICOSLG/Me:1


"An ICOS ligand (human) that has been methylated on the residue at the position equivalent to Cys-113 of the amino acid sequence represented by UniProtKB:O75144-1. Example: UniProtKB:O75144-1, Cys-113, MOD:00660." [IEDB_epitope:1004857, PRO:DNx]


organism-gene



PR:Q9JHJ8

ICOS ligand (mouse)

mICOSLG


"An ICOS ligand that is encoded in the genome of mouse." [OMA:Q9JHJ8, PRO:DNx]


organism-sequence



PR:Q9JHJ8-1

ICOS ligand isoform m1 (mouse)

mICOSLG/iso:m1


"An ICOS ligand (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JHJ8-1." [PRO:DNx, UniProtKB:Q9JHJ8]


organism-sequence



PR:Q9JHJ8-2

ICOS ligand isoform m2 (mouse)

mICOSLG/iso:m2


"An ICOS ligand (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JHJ8-2." [PRO:DNx, UniProtKB:Q9JHJ8]


gene



PR:000001438

CD80 molecule

CD80


"A B7-related protein that is a translation product of the human CD80 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P33681

T-lymphocyte activation antigen CD80 (human)

hCD80


"A CD80 molecule that is encoded in the genome of human." [PRO:WCB, UniProtKB:P33681]


organism-sequence



PR:P33681-1

T-lymphocyte activation antigen CD80 isoform h1 (human)

hCD80/iso:h1


"A T-lymphocyte activation antigen CD80 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33681-1." [PRO:DNx, UniProtKB:P33681]


organism-sequence



PR:P33681-2

T-lymphocyte activation antigen CD80 isoform h2 (human)

hCD80/iso:h2


"A T-lymphocyte activation antigen CD80 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33681-2." [PRO:DNx, UniProtKB:P33681]


organism-sequence



PR:P33681-3

T-lymphocyte activation antigen CD80 isoform h3 (human)

hCD80/iso:h3


"A T-lymphocyte activation antigen CD80 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P33681-3." [PRO:DNx, UniProtKB:P33681]


organism-modification



PR:000046650

T-lymphocyte activation antigen CD80, signal peptide removed form (human)

hCD80/SigPep-


"A T-lymphocyte activation antigen CD80 (human) that has had the signal peptide removed. UniProtKB:P33681, 35-288." [PRO:DNx, Reactome:R-HSA-179789]


organism-gene



PR:Q00609

T-lymphocyte activation antigen CD80 (mouse)

mCD80


"A CD80 molecule that is encoded in the genome of mouse." [OMA:Q00609, PRO:DNx]


organism-sequence



PR:Q00609-1

T-lymphocyte activation antigen CD80 isoform m1 (mouse)

mCD80/iso:m1


"A T-lymphocyte activation antigen CD80 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00609-1." [PRO:DNx, UniProtKB:Q00609]


organism-sequence



PR:Q00609-2

T-lymphocyte activation antigen CD80 isoform m2 (mouse)

mCD80/iso:m2


"A T-lymphocyte activation antigen CD80 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00609-2." [PRO:DNx, UniProtKB:Q00609]


modification



PR:000018477

CD80 molecule, signal peptide removed form

CD80/SigPep-


"A CD80 molecule that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000046650

T-lymphocyte activation antigen CD80, signal peptide removed form (human)

hCD80/SigPep-


"A T-lymphocyte activation antigen CD80 (human) that has had the signal peptide removed. UniProtKB:P33681, 35-288." [PRO:DNx, Reactome:R-HSA-179789]


gene



PR:000001543

programmed cell death 1 ligand 1

CD274


"A B7-related protein that is a translation product of the human CD274 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:Q9EP73

programmed cell death 1 ligand 1 (mouse)

mCD274


"A programmed cell death 1 ligand 1 that is encoded in the genome of mouse." [OMA:Q9EP73, PRO:DNx]


organism-gene



PR:Q9NZQ7

programmed cell death 1 ligand 1 (human)

hCD274


"A programmed cell death 1 ligand 1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9NZQ7]


organism-sequence



PR:Q9NZQ7-1

programmed cell death 1 ligand 1 isoform h1 (human)

hCD274/iso:h1


"A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-1." [PRO:DNx, UniProtKB:Q9NZQ7]


organism-sequence



PR:Q9NZQ7-2

programmed cell death 1 ligand 1 isoform h2 (human)

hCD274/iso:h2


"A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-2." [PRO:DNx, UniProtKB:Q9NZQ7]


organism-sequence



PR:Q9NZQ7-3

programmed cell death 1 ligand 1 isoform h3 (human)

hCD274/iso:h3


"A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-3." [PRO:DNx, UniProtKB:Q9NZQ7]


organism-sequence



PR:Q9NZQ7-4

programmed cell death 1 ligand 1 isoform h4 (human)

hCD274/iso:h4


"A programmed cell death 1 ligand 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NZQ7-4." [PRO:DNx, UniProtKB:Q9NZQ7]


organism-modification



PR:000046626

programmed cell death 1 ligand 1, signal peptide removed form (human)

hCD274/SigPep-


"A programmed cell death 1 ligand 1 (human) that has had the signal peptide removed. UniProtKB:Q9NZQ7, 19-290." [PRO:DNx, Reactome:R-HSA-3211776]


organism-modification



PR:000078498

programmed cell death 1 ligand 1 deaminated 1 (human)

hCD274/Deam:1


"A programmed cell death 1 ligand 1 (human) that has been deaminated on the residue at the position equivalent to Asn-192 of the amino acid sequence represented by UniProtKB:Q9NZQ7-1. Example: UniProtKB:Q9NZQ7-1, Asn-192, MOD:00684." [IEDB_epitope:633218, IEDB_epitope:633220, PRO:DNx]


gene



PR:000001544

programmed cell death 1 ligand 2

PDCD1LG2


"A B7-related protein that is a translation product of the human PDCD1LG2 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:Q9BQ51

programmed cell death 1 ligand 2 (human)

hPDCD1LG2


"A programmed cell death 1 ligand 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q9BQ51]


organism-sequence



PR:Q9BQ51-1

programmed cell death 1 ligand 2 isoform h1 (human)

hPDCD1LG2/iso:h1


"A programmed cell death 1 ligand 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ51-1." [PRO:DNx, UniProtKB:Q9BQ51]


organism-sequence



PR:Q9BQ51-2

programmed cell death 1 ligand 2 isoform h2 (human)

hPDCD1LG2/iso:h2


"A programmed cell death 1 ligand 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ51-2." [PRO:DNx, UniProtKB:Q9BQ51]


organism-sequence



PR:Q9BQ51-3

programmed cell death 1 ligand 2 isoform h3 (human)

hPDCD1LG2/iso:h3


"A programmed cell death 1 ligand 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ51-3." [PRO:DNx, UniProtKB:Q9BQ51]


organism-modification



PR:000048714

programmed cell death 1 ligand 2, signal peptide removed form (human)

hPDCD1LG2/SigPep-


"A programmed cell death 1 ligand 2 (human) that has had the signal peptide removed. UniProtKB:Q9BQ51, 20-273." [PRO:DNx, Reactome:R-HSA-3211774]


organism-modification



PR:000071332

programmed cell death 1 ligand 2 deaminated 1 (human)

hPDCD1LG2/Deam:1


"A programmed cell death 1 ligand 2 (human) that has been deaminated on the residue at the position equivalent to Asn-37 of the amino acid sequence represented by UniProtKB:Q9BQ51-1. Example: UniProtKB:Q9BQ51-1, Asn-37, MOD:00684." [IEDB_epitope:1981765, IEDB_epitope:2000246, PRO:DNx]


organism-gene



PR:Q9WUL5

programmed cell death 1 ligand 2 (mouse)

mPDCD1LG2


"A programmed cell death 1 ligand 2 that is encoded in the genome of mouse." [OMA:Q9WUL5, PRO:DNx]


modification



PR:000018512

programmed cell death 1 ligand 2, signal peptide removed form

PDCD1LG2/SigPep-


"A programmed cell death 1 ligand 2 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000048714

programmed cell death 1 ligand 2, signal peptide removed form (human)

hPDCD1LG2/SigPep-


"A programmed cell death 1 ligand 2 (human) that has had the signal peptide removed. UniProtKB:Q9BQ51, 20-273." [PRO:DNx, Reactome:R-HSA-3211774]