back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - ADAM 17 endopeptidase
PR:000001279 - http://purl.obolibrary.org/obo/PR_000001279
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001279   
  PRO nameADAM 17 endopeptidase 
  Synonyms
PRO-Short-label: EXACT:ADAM17
Gene-based: RELATED:CSVP | TACE
Other: EXACT:ADAM 17 | CD156b | snake venom-like protease | TNF-alpha convertase | TNF-alpha-converting enzyme
  Definition"A protein that is a translation product of the human ADAM17 gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification1                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:1662
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000001279

ADAM 17 endopeptidase

ADAM17


"A protein that is a translation product of the human ADAM17 gene or a 1:1 ortholog thereof." [PRO:WCB]


organism-gene



PR:P78536

disintegrin and metalloproteinase domain-containing protein 17 (human)

hADAM17


"An ADAM 17 endopeptidase that is encoded in the genome of human." [PRO:WCB, UniProtKB:P78536]


organism-sequence



PR:P78536-1

disintegrin and metalloproteinase domain-containing protein 17 isoform A (human)

hADAM17/iso:A


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78536-1." [PRO:DNx, UniProtKB:P78536]


organism-sequence



PR:P78536-2

disintegrin and metalloproteinase domain-containing protein 17 isoform B (human)

hADAM17/iso:B


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P78536-2." [PRO:DNx, UniProtKB:P78536]


organism-modification



PR:000045859

disintegrin and metalloproteinase domain-containing protein 17 phosphorylated 1 (human)

hADAM17/Phos:1


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been phosphorylated on the residue at the position equivalent to Thr-735 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Thr-735, MOD:00047." [iPTMnet:P78536, PMID:12058067, PMID:18722532]


organism-modification



PR:000056691

disintegrin and metalloproteinase domain-containing protein 17 N-glycosylated 1 (human)

hADAM17/NGlyco:1


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been N-glycosylated at the residue equivalent to Asn-264 of the amino acid sequence represented by UniProtKB:P78536-1, in which the glycan composition is represented by GlyTouCan:G37399XV. Example: UniProtKB:P78536-1, Asn-264, MOD:00160~GNO:G37399XV." [GlyGen:P78536-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000056692

disintegrin and metalloproteinase domain-containing protein 17 N-glycosylated 2 (human)

hADAM17/NGlyco:2


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been N-glycosylated at the residue equivalent to Asn-264 of the amino acid sequence represented by UniProtKB:P78536-1, in which the glycan composition is represented by GlyTouCan:G83633GK. Example: UniProtKB:P78536-1, Asn-264, MOD:00160~GNO:G83633GK." [GlyGen:P78536-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000074459

disintegrin and metalloproteinase domain-containing protein 17 methylated 1 (human)

hADAM17/Me:1


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been methylated on the residue at the position equivalent to Cys-469 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Cys-469, MOD:00660." [IEDB_epitope:1009153, PRO:DNx]


organism-modification



PR:000076090

disintegrin and metalloproteinase domain-containing protein 17 deaminated 1 (human)

hADAM17/Deam:1


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been deaminated on the residue at the position equivalent to Asn-103 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Asn-103, MOD:00684." [IEDB_epitope:1343685, PRO:DNx]


organism-modification



PR:000078552

disintegrin and metalloproteinase domain-containing protein 17, mature form (human)

hADAM17/mature


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P78536-1, 215-824." [PRO:DNx, Reactome:R-HSA-179878, Reactome:R-HSA-9662839, Reactome:R-HSA-9663048]


organism-modification



PR:000081164

disintegrin and metalloproteinase domain-containing protein 17 methylated 2 (human)

hADAM17/Me:2


"A disintegrin and metalloproteinase domain-containing protein 17 (human) that has been methylated on the residue at the position equivalent to Cys-333 of the amino acid sequence represented by UniProtKB:P78536-1. Example: UniProtKB:P78536-1, Cys-333, MOD:00660." [IEDB_epitope:1019927, PRO:DNx]


organism-gene



PR:Q5QHR9

tumor necrosis factor alpha converting enzyme (chicken)

chick-ADAM17


"An ADAM 17 endopeptidase that is encoded in the genome of chicken." [OMA:Q5QHR9, PRO:DNx]


organism-gene



PR:Q94316

disintegrin and metalloproteinase domain-containing protein 17 homolog (worm)

ADAM17 (worm)


"An ADAM 17 endopeptidase that is encoded in the genome of worm." [PANTHER:PTHR11905:SF3, PRO:DNx]


organism-gene



PR:Q9VAC5

ADAM 17-like protease (fruit fly)

fly-ADAM17


"An ADAM 17 endopeptidase that is encoded in the genome of fruit fly." [OMA:Q9VAC5, PRO:DNx]


organism-sequence



PR:Q9VAC5-1

ADAM 17-like protease isoform A (fruit fly)

fly-ADAM17/iso:A


"An ADAM 17-like protease (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9VAC5-1." [PRO:DNx, UniProtKB:Q9VAC5]


organism-sequence



PR:Q9VAC5-2

ADAM 17-like protease isoform B (fruit fly)

fly-ADAM17/iso:B


"An ADAM 17-like protease (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9VAC5-2." [PRO:DNx, UniProtKB:Q9VAC5]


organism-gene



PR:Q9Z0F8

disintegrin and metalloproteinase domain-containing protein 17 (mouse)

mADAM17


"An ADAM 17 endopeptidase that is encoded in the genome of mouse." [OMA:Q9Z0F8, PRO:DNx]


organism-sequence



PR:Q9Z0F8-1

disintegrin and metalloproteinase domain-containing protein 17 isoform Long (mouse)

mADAM17/iso:Long


"A disintegrin and metalloproteinase domain-containing protein 17 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z0F8-1." [PRO:DNx, UniProtKB:Q9Z0F8]


organism-sequence



PR:Q9Z0F8-2

disintegrin and metalloproteinase domain-containing protein 17 isoform Short (mouse)

mADAM17/iso:Short


"A disintegrin and metalloproteinase domain-containing protein 17 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z0F8-2." [PRO:DNx, UniProtKB:Q9Z0F8]


organism-gene



PR:Q9Z1K9

disintegrin and metalloproteinase domain-containing protein 17 (rat)

rADAM17


"An ADAM 17 endopeptidase that is encoded in the genome of rat." [OMA:Q9Z1K9, PRO:DNx]


modification



PR:000018362

ADAM 17 endopeptidase proteolytic cleavage product

ADAM17/ClvPrd


"An ADAM 17 endopeptidase that has been processed by proteolytic cleavage." [PRO:DNx]