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Protein Ontology report - adhesion G protein-coupled receptor L1
PR:000001233 - http://purl.obolibrary.org/obo/PR_000001233
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001233   
  PRO nameadhesion G protein-coupled receptor L1 
  Synonyms
PRO-Short-label: EXACT:ADGRL1
Gene-based: RELATED:KIAA0821 | LEC2 | LPHN1
Other: EXACT:calcium-independent alpha-latrotoxin receptor 1 | CIRL-1 | latrophilin-1 | lectomedin-2
RELATED:Cirl | Cirl1 | Cl1
  Definition"A calcium-independent alpha-latrotoxin receptor that is a translation product of the human ADGRL1 gene or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorygene 
  ParentPR:000001124 calcium-independent alpha-latrotoxin receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence4                                                  Organism-Sequence 8                                        
         Modification7                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:206
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001233
adhesion G protein-coupled receptor L1
ADGRL1
"A calcium-independent alpha-latrotoxin receptor that is a translation product of the human ADGRL1 gene or a 1:1 ortholog thereof." [PRO:CNA]

organism-gene


PR:O88917
adhesion G protein-coupled receptor L1 (rat)
rADGRL1
"An adhesion G protein-coupled receptor L1 that is encoded in the genome of rat." [OMA:O88917, PRO:DNx]

organism-sequence


PR:O88917-1
adhesion G protein-coupled receptor L1 isoform 1 (rat)
rADGRL1/iso:1
"An adhesion G protein-coupled receptor L1 isoform 1 that is encoded in the genome of rat." [PRO:CNA]

organism-sequence


PR:O88917-2
adhesion G protein-coupled receptor L1 isoform 2 (rat)
rADGRL1/iso:2
"An adhesion G protein-coupled receptor L1 isoform 2 that is encoded in the genome of rat." [PRO:CNA]
Yes
organism-sequence


PR:O88917-3
adhesion G protein-coupled receptor L1 isoform 3 (rat)
rADGRL1/iso:3
"An adhesion G protein-coupled receptor L1 isoform 3 that is encoded in the genome of rat." [PRO:CNA]
Yes
organism-sequence


PR:O88917-4
adhesion G protein-coupled receptor L1 isoform 4 (rat)
rADGRL1/iso:4
"An adhesion G protein-coupled receptor L1 isoform 4 that is encoded in the genome of rat." [PRO:CNA]
Yes
organism-modification


PR:000036603
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat)
rADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 in rat. UniProtKB:O88917-4, 25-837." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
organism-modification


PR:000036604
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat)
rADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 in rat. UniProtKB:O88917-4, 838-1471." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
organism-gene


PR:O94910
adhesion G protein-coupled receptor L1 (human)
hADGRL1
"An adhesion G protein-coupled receptor L1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:O94910]

organism-sequence


PR:O94910-1
adhesion G protein-coupled receptor L1 isoform h1 (human)
hADGRL1/iso:h1
"An adhesion G protein-coupled receptor L1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O94910-1." [PRO:DNx, UniProtKB:O94910]

organism-sequence


PR:O94910-2
adhesion G protein-coupled receptor L1 isoform h2 (human)
hADGRL1/iso:h2
"An adhesion G protein-coupled receptor L1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O94910-2." [PRO:DNx, UniProtKB:O94910]

organism-modification


PR:000050889
adhesion G protein-coupled receptor L1 O-glycosylated 1 (human)
hADGRL1/OGlyco:1
"An adhesion G protein-coupled receptor L1 (human) that has been O-glycosylated at the residue equivalent to Thr-464 of the amino acid sequence represented by UniProtKB:O94910-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O94910-1, Thr-464, MOD:00005~GNO:G43417UB." [GlyGen:O94910-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000070362
adhesion G protein-coupled receptor L1 phosphorylated 1 (human)
hADGRL1/Phos:1
"An adhesion G protein-coupled receptor L1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-731 of the amino acid sequence represented by UniProtKB:O94910-1. Example: UniProtKB:O94910-1, Tyr-731, MOD:00048." [IEDB_epitope:2149158, PRO:DNx]

organism-modification


PR:000070591
adhesion G protein-coupled receptor L1 phosphorylated 2 (human)
hADGRL1/Phos:2
"An adhesion G protein-coupled receptor L1 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-326 of the amino acid sequence represented by UniProtKB:O94910-1. Example: UniProtKB:O94910-1, Tyr-326, MOD:00048." [IEDB_epitope:850209, PRO:DNx]

organism-modification


PR:000083806
adhesion G protein-coupled receptor L1 cysteinylated 1 (human)
hADGRL1/Cyst:1
"An adhesion G protein-coupled receptor L1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-83 of the amino acid sequence represented by UniProtKB:O94910-1. Example: UniProtKB:O94910-1, Cys-83, MOD:00765." [IEDB_epitope:1570891, PRO:DNx]

organism-gene


PR:Q80TR1
adhesion G protein-coupled receptor L1 (mouse)
mADGRL1
"An adhesion G protein-coupled receptor L1 that is encoded in the genome of mouse." [OMA:Q80TR1, PRO:DNx]

organism-sequence


PR:Q80TR1-1
adhesion G protein-coupled receptor L1 isoform 1 (mouse)
mADGRL1/iso:1
"An adhesion G protein-coupled receptor L1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

organism-sequence


PR:Q80TR1-2
adhesion G protein-coupled receptor L1 isoform m2 (mouse)
mADGRL1/iso:m2
"An adhesion G protein-coupled receptor L1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80TR1-2." [PRO:DNx, UniProtKB:Q80TR1]

organism-modification


PR:000029940
adhesion G protein-coupled receptor L1 phosphorylated 1 (mouse)
mADGRL1/Phos:1
"An adhesion G protein-coupled receptor L1 phosphorylated 1 in mouse. UniProtKB:Q80TR1, Ser-1369, MOD:00046." [PMID:17114649, PRO:HJD]

sequence


PR:000001263
adhesion G protein-coupled receptor L1 isoform 1
ADGRL1/iso:1
"An adhesion G protein-coupled receptor L1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88917-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:O88917-1
adhesion G protein-coupled receptor L1 isoform 1 (rat)
rADGRL1/iso:1
"An adhesion G protein-coupled receptor L1 isoform 1 that is encoded in the genome of rat." [PRO:CNA]

modification


PR:000026615
adhesion G protein-coupled receptor L1 isoform 1, signal peptide removed form
ADGRL1/iso:1/SigPep-
"An adhesion G protein-coupled receptor L1 isoform 1 that has had the signal peptide removed." [PRO:DNx]

sequence


PR:000001264
adhesion G protein-coupled receptor L1 isoform 2
ADGRL1/iso:2
"An adhesion G protein-coupled receptor L1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88917-2 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:O88917-2
adhesion G protein-coupled receptor L1 isoform 2 (rat)
rADGRL1/iso:2
"An adhesion G protein-coupled receptor L1 isoform 2 that is encoded in the genome of rat." [PRO:CNA]
Yes
organism-sequence


PR:Q80TR1-1
adhesion G protein-coupled receptor L1 isoform 1 (mouse)
mADGRL1/iso:1
"An adhesion G protein-coupled receptor L1 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]

sequence


PR:000001265
adhesion G protein-coupled receptor L1 isoform 3
ADGRL1/iso:3
"An adhesion G protein-coupled receptor L1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88917-3 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:O88917-3
adhesion G protein-coupled receptor L1 isoform 3 (rat)
rADGRL1/iso:3
"An adhesion G protein-coupled receptor L1 isoform 3 that is encoded in the genome of rat." [PRO:CNA]
Yes
sequence


PR:000001266
adhesion G protein-coupled receptor L1 isoform 4
ADGRL1/iso:4
"An adhesion G protein-coupled receptor L1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88917-4 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:O88917-4
adhesion G protein-coupled receptor L1 isoform 4 (rat)
rADGRL1/iso:4
"An adhesion G protein-coupled receptor L1 isoform 4 that is encoded in the genome of rat." [PRO:CNA]
Yes
organism-modification


PR:000036603
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat)
rADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 in rat. UniProtKB:O88917-4, 25-837." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
organism-modification


PR:000036604
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat)
rADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 in rat. UniProtKB:O88917-4, 838-1471." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000021918
adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form
ADGRL1/iso:4/SigPep-
"An adhesion G protein-coupled receptor L1 isoform 4 that has had the signal peptide removed. Example: UniProtKB:O88917-4, 25-1471." [PRO:DNx]

modification


PR:000001274
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1
ADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form that is the N-terminal product of the cleavage upstream of a Thr residue within the GPS domain, corresponding to Thr-838 in the rat sequence UniProtKB:O88917-4. This form remains non-covalently bound to the C-terminal product. Example: UniProtKB:O88917-4, 25-837." [PMID:12270923]

organism-modification


PR:000036603
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat)
rADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 in rat. UniProtKB:O88917-4, 25-837." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000001275
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2
ADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form that is the C-terminal product of the cleavage upstream of a Thr residue within the GPS domain, corresponding to Thr-838 in the rat sequence UniProtKB:O88917-4. Example: UniProtKB:O88917-4, 838-1471." [PMID:12270923]

organism-modification


PR:000036604
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat)
rADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 in rat. UniProtKB:O88917-4, 838-1471." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000021934
adhesion G protein-coupled receptor L1 proteolytic cleavage product
ADGRL1/ClvPrd
"An adhesion G protein-coupled receptor L1 that has been processed by proteolytic cleavage." [PRO:DAN]

modification


PR:000001274
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1
ADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form that is the N-terminal product of the cleavage upstream of a Thr residue within the GPS domain, corresponding to Thr-838 in the rat sequence UniProtKB:O88917-4. This form remains non-covalently bound to the C-terminal product. Example: UniProtKB:O88917-4, 25-837." [PMID:12270923]

organism-modification


PR:000036603
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat)
rADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 in rat. UniProtKB:O88917-4, 25-837." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000001275
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2
ADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form that is the C-terminal product of the cleavage upstream of a Thr residue within the GPS domain, corresponding to Thr-838 in the rat sequence UniProtKB:O88917-4. Example: UniProtKB:O88917-4, 838-1471." [PMID:12270923]

organism-modification


PR:000036604
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat)
rADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 in rat. UniProtKB:O88917-4, 838-1471." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000026614
adhesion G protein-coupled receptor L1, signal peptide removed form
ADGRL1/SigPep-
"An adhesion G protein-coupled receptor L1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000021918
adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form
ADGRL1/iso:4/SigPep-
"An adhesion G protein-coupled receptor L1 isoform 4 that has had the signal peptide removed. Example: UniProtKB:O88917-4, 25-1471." [PRO:DNx]

modification


PR:000001274
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1
ADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form that is the N-terminal product of the cleavage upstream of a Thr residue within the GPS domain, corresponding to Thr-838 in the rat sequence UniProtKB:O88917-4. This form remains non-covalently bound to the C-terminal product. Example: UniProtKB:O88917-4, 25-837." [PMID:12270923]

organism-modification


PR:000036603
adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 (rat)
rADGRL1/iso:4/Clv:1
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 1 in rat. UniProtKB:O88917-4, 25-837." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000001275
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2
ADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4, signal peptide removed form that is the C-terminal product of the cleavage upstream of a Thr residue within the GPS domain, corresponding to Thr-838 in the rat sequence UniProtKB:O88917-4. Example: UniProtKB:O88917-4, 838-1471." [PMID:12270923]

organism-modification


PR:000036604
adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 (rat)
rADGRL1/iso:4/Clv:2
"An adhesion G protein-coupled receptor L1 isoform 4 cleaved 2 in rat. UniProtKB:O88917-4, 838-1471." [PMID:12270923, PMID:12270924, PMID:9208860, PRO:CNA]
Yes
modification


PR:000026615
adhesion G protein-coupled receptor L1 isoform 1, signal peptide removed form
ADGRL1/iso:1/SigPep-
"An adhesion G protein-coupled receptor L1 isoform 1 that has had the signal peptide removed." [PRO:DNx]

modification


PR:000029939
adhesion G protein-coupled receptor L1 phosphorylated 1
ADGRL1/Phos:1
"An adhesion G protein-coupled receptor L1 that has been phosphorylated on the residue at the position equivalent to Ser-1369 of the amino acid sequence represented by UniProtKB:Q80TR1. Example: UniProtKB:Q80TR1, Ser-1369, MOD:00046." [PMID:17114649, PRO:HJD]

organism-modification


PR:000029940
adhesion G protein-coupled receptor L1 phosphorylated 1 (mouse)
mADGRL1/Phos:1
"An adhesion G protein-coupled receptor L1 phosphorylated 1 in mouse. UniProtKB:Q80TR1, Ser-1369, MOD:00046." [PMID:17114649, PRO:HJD]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036603 rADGRL1/iso:4/Clv:1
UniProtKB:O88917-4, 25-837		 enablescontributes_to GO:0016524 latrotoxin receptor activity PMID:12270924; PMID:9208860
located_inGO:0016020 membrane PMID:12270923
GO:0043235 receptor complex PMID:12270924; PMID:9208860
PR:000036604 rADGRL1/iso:4/Clv:2
UniProtKB:O88917-4, 838-1471		 enablescontributes_to GO:0016524 latrotoxin receptor activity PMID:12270924; PMID:9208860
located_inGO:0043235 receptor complex PMID:12270924; PMID:9208860
PR:O88917-2 rADGRL1/iso:2 enablesGO:0016524 latrotoxin receptor activity PMID:9208860
PR:O88917-3 rADGRL1/iso:3 enablesGO:0016524 latrotoxin receptor activity PMID:9208860
PR:O88917-4 rADGRL1/iso:4 enablesGO:0016524 latrotoxin receptor activity PMID:9208860