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Protein Ontology report - endothelin receptor
PR:000001133 - http://purl.obolibrary.org/obo/PR_000001133
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000001133   
  PRO nameendothelin receptor 
  Definition"A rhodopsin-like G-protein coupled receptor that is a translation product of the human EDNRA or EDNRB genes, 1:1 orthologs thereof, or pro-orthologs thereof. The active form binds endothelins." [PRO:WCB, PRO:XQ] 
  CommentPro-orthology refers to, in this case, after-speciation gene duplication in the non-human species (aka 1:many orthology). 
  PRO Categoryfamily 
  ParentPR:000001094 rhodopsin-like G-protein coupled receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 10                                        
         Sequence2                                                  Organism-Sequence 11                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF001842;IUPHARfam:21
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000001133

endothelin receptor

ACKR1


"A rhodopsin-like G-protein coupled receptor that is a translation product of the human EDNRA or EDNRB genes, 1:1 orthologs thereof, or pro-orthologs thereof. The active form binds endothelins." [PRO:WCB, PRO:XQ]


gene



PR:000001221

endothelin-1 receptor

EDNRA


"An endothelin receptor that is a translation product of the human EDNRA gene or a 1:1 ortholog thereof. The active form binds endothelin 1 (ET-1) and ET-2 with much higher affinity than ET-3." [PMID:12037137, PRO:WCB]


organism-gene



PR:P21450

endothelin-1 receptor (cow)

cow-EDNRA


"An endothelin-1 receptor that is encoded in the genome of cow." [OMA:P21450, PRO:DNx]


organism-gene



PR:P25101

endothelin-1 receptor (human)

hEDNRA


"An endothelin-1 receptor that is encoded in the genome of human." [PRO:WCB, UniProtKB:P25101]


organism-sequence



PR:P25101-1

endothelin-1 receptor isoform 1 (human)

hEDNRA/iso:1


"An endothelin-1 receptor isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P25101-2

endothelin-1 receptor isoform h2 (human)

hEDNRA/iso:h2


"An endothelin-1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25101-2." [PRO:DNx, UniProtKB:P25101]


organism-sequence



PR:P25101-3

endothelin-1 receptor isoform h3 (human)

hEDNRA/iso:h3


"An endothelin-1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25101-3." [PRO:DNx, UniProtKB:P25101]


organism-sequence



PR:P25101-4

endothelin-1 receptor isoform h4 (human)

hEDNRA/iso:h4


"An endothelin-1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25101-4." [PRO:DNx, UniProtKB:P25101]


organism-sequence



PR:P25101-5

endothelin-1 receptor isoform h5 (human)

hEDNRA/iso:h5


"An endothelin-1 receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25101-5." [PRO:DNx, UniProtKB:P25101]


organism-modification



PR:000047245

endothelin-1 receptor, signal peptide removed form (human)

hEDNRA/SigPep-


"An endothelin-1 receptor (human) that has had the signal peptide removed. UniProtKB:P25101, 21-427." [PRO:DNx, Reactome:R-HSA-388549]


organism-gene



PR:P26684

endothelin-1 receptor (rat)

rEDNRA


"An endothelin-1 receptor that is encoded in the genome of rat." [OMA:P26684, PRO:DNx]


organism-gene



PR:Q29010

endothelin-1 receptor (pig)

pig-EDNRA


"An endothelin-1 receptor that is encoded in the genome of pig." [OMA:Q29010, PRO:DNx]


organism-gene



PR:Q61614

endothelin-1 receptor (mouse)

mEDNRA


"An endothelin-1 receptor that is encoded in the genome of mouse." [OMA:Q61614, PRO:DNx]


organism-sequence



PR:Q61614-1

endothelin-1 receptor isoform 1 (mouse)

mEDNRA/iso:1


"An endothelin-1 receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000039131

endothelin-1 receptor isoform 1

EDNRA/iso:1


"An endothelin-1 receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P25101-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P25101-1

endothelin-1 receptor isoform 1 (human)

hEDNRA/iso:1


"An endothelin-1 receptor isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q61614-1

endothelin-1 receptor isoform 1 (mouse)

mEDNRA/iso:1


"An endothelin-1 receptor isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000001222

endothelin receptor type B

EDNRB


"An endothelin receptor that is a translation product of the human EDNRB gene or a 1:1 ortholog thereof. The active form binds endothelin 1 (ET-1), ET-2, and ET-3 with equal affinity." [PMID:12037137, PRO:WCB]


organism-gene



PR:P21451

endothelin receptor type B (rat)

rEDNRB


"An endothelin receptor type B that is encoded in the genome of rat." [OMA:P21451, PRO:DNx]


organism-sequence



PR:P21451-1

endothelin receptor type B isoform 1 (rat)

rEDNRB/iso:1


"An endothelin receptor type B isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P24530

endothelin receptor type B (human)

hEDNRB


"An endothelin receptor type B that is encoded in the genome of human." [PRO:WCB, UniProtKB:P24530]


organism-sequence



PR:P24530-1

endothelin receptor type B isoform A (human)

hEDNRB/iso:A


"An endothelin receptor type B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24530-1." [PRO:DNx, UniProtKB:P24530]


organism-sequence



PR:P24530-2

endothelin receptor type B isoform B (human)

hEDNRB/iso:B


"An endothelin receptor type B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24530-2." [PRO:DNx, UniProtKB:P24530]


organism-sequence



PR:P24530-3

endothelin receptor type B isoform C (human)

hEDNRB/iso:C


"An endothelin receptor type B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24530-3." [PRO:DNx, UniProtKB:P24530]


organism-modification



PR:000047246

endothelin B receptor, signal peptide removed form (human)

hEDNRB/SigPep-


"An endothelin receptor type B (human) that has had the signal peptide removed. UniProtKB:P24530, 27-442." [PRO:DNx, Reactome:R-HSA-388550]


organism-modification



PR:000074542

endothelin receptor type B methylated 1 (human)

hEDNRB/Me:1


"An endothelin receptor type B (human) that has been methylated on the residue at the position equivalent to Cys-420 of the amino acid sequence represented by UniProtKB:P24530-1. Example: UniProtKB:P24530-1, Cys-420, MOD:00660." [IEDB_epitope:1008256, PRO:DNx]


organism-modification



PR:000084663

endothelin receptor type B methylated 2 (human)

hEDNRB/Me:2


"An endothelin receptor type B (human) that has been methylated on the residue at the position equivalent to Cys-8 of the amino acid sequence represented by UniProtKB:P24530-1. Example: UniProtKB:P24530-1, Cys-8, MOD:00660." [IEDB_epitope:1049684, PRO:DNx]


organism-gene



PR:P28088

endothelin receptor type B (cow)

cow-EDNRB


"An endothelin receptor type B that is encoded in the genome of cow." [OMA:P28088, PRO:DNx]


organism-gene



PR:P35463

endothelin receptor type B (pig)

pig-EDNRB


"An endothelin receptor type B that is encoded in the genome of pig." [OMA:P35463, PRO:DNx]


organism-gene



PR:P48302

endothelin receptor type B (mouse)

mEDNRB


"An endothelin receptor type B that is encoded in the genome of mouse." [OMA:P48302, PRO:DNx]


organism-sequence



PR:P48302-1

endothelin receptor type B isoform 1 (mouse)

mEDNRB/iso:1


"An endothelin receptor type B isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000039536

endothelin receptor type B isoform 1

EDNRB/iso:1


"An endothelin receptor type B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P48302-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P21451-1

endothelin receptor type B isoform 1 (rat)

rEDNRB/iso:1


"An endothelin receptor type B isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P48302-1

endothelin receptor type B isoform 1 (mouse)

mEDNRB/iso:1


"An endothelin receptor type B isoform 1 that is encoded in the genome of mouse." [PRO:DNx]